Abstract: A method of controlling a secondary-side rectifier switch of a flyback converter, can include: detecting a slope parameter of a secondary-side detection voltage along a predetermined direction, where the secondary-side detection voltage is configured to represent a voltage across a secondary winding of the flyback converter; and controlling the secondary-side rectifier switch to turn on when the slope parameter is greater than a slope parameter threshold, and a relationship between the secondary-side detection voltage and the ON threshold meets a predetermined requirement.

Abstract: Crystals of pembrolizumab and structurally similar anti-PD-1 monoclonal antibodies are provided, as well as methods of producing such crystals, and uses of compositions comprising such antibody crystals, e.g. in treatment of cancers. The present invention satisfies these needs and more by providing pembrolizumab crystals and a method producing pembrolizumab crystals. One embodiment of the method of the invention produces crystals suitable for X-ray diffraction, and the inventors herein used such crystals to solve the three-dimensional structure of pembrolizumab to 2.3 A resolution.

Abstract: Example minimalist magnetic resonance imaging (MRI) radio frequency (RF) coils that are connected to off coil circuitry by capacitive coupling plates are described. A minimalist MRI RF coil may have some elements that form a traditional coil located off the coil in off coil circuitry. An MR procedure may involve a number of minimalist MRI RF coils that are moved through an excitation zone as a patient is moved through the excitation zone. Example minimalist MRI RF coils may be selectively connected to off coil circuitry while the coils are in the excitation zone. The coupling may be made by capacitive coupling plates. Unlike conventional systems, example systems have capacitive coupling plates with properties that facilitate maintaining a constant capacitance between a coupling plate associated with the coil and coupling plates associated with the off coil circuitry as the coupling plates move relative to each other.

Abstract: Apparatus associated with improved magnetic resonance imaging (MRI) guided needle biopsy procedures (e.g., breast needle biopsy) are described. One example apparatus includes a support structure configured to support a patient in a face-down prone position where a breast of the patient is positioned in a first free hanging pre-imaging position. The example apparatus includes an immobilization structure configured to reposition the breast into an immobilized position suitable for MRI and for medical instrument access. The immobilization structure may include a removable biopsy plate, a removable side coil, a pressure plate, and MRI coils. The MRI coils are configured to be repositioned from a first position associated with the free hanging pre-imaging position to a second position associated with the immobilized position to facilitate improving the signal to noise ratio associated with signal received from the breast through the MRI coils.

Abstract: A perpendicular magnetic recording (PMR) writer is configured to magnetically record data on a rotatable disk surface. The PMR writer including a pole tip, side shields, an air-bearing surface (ABS) region, a yoke region comprising Silicon Dioxide (SiO2), side gaps and a plurality of throat regions. The side gaps are arranged respectively between the pole tip and the side shields and include SiO2. A side gap width of the plurality of throat regions increases with a side shield throat height above the ABS region for each of the throat regions. The side gap width has a different width variation in each of the throat regions.

Abstract: Example magnetic resonance imaging (MRI) radio frequency (RF) coils are described. An MRI RF coil may include an LC circuit and an integrated decoupling circuit. The integrated decoupling circuit may include a wire or other conductor that is connected to the LC circuit and that is positioned within a defined distance of the LC circuit. The integrated decoupling circuit may include a PIN diode and a tunable element. The tunable element may be tunable with respect to resistance, capacitance, or inductance, and thus may control, at least in part, the frequency at which the LC circuit resonates during RF transmission. The example MRI RF coil has more than one point of high impedance, which facilitates reducing heating and operational issues associated with conventional coils.

Abstract: A magnetic resonance imaging (MRI) radio frequency (RF) coil array configured to operate in a transmit (Tx) mode or in a receive (Rx) mode, the MRI RF coil array comprising at least one single-layer RF coil element. The at least one RF coil element includes a resonant LC coil, a matching Tx/Rx switch circuit, and a preamplifier. The matching and Tx/Rx switch circuit, when operating in Tx mode, electrically isolates the LC coil from the preamplifier upon the LC coil resonating with a primary coil at the primary coil's working frequency. The LC coil, upon resonating with the primary coil at the working frequency, generates a local amplified Tx field based on an induced current in the LC coil. A magnitude or a phase of the induced current is independently adjustable. The matching and Tx/Rx switch circuit, when in Rx mode, electrically connects the LC coil with the preamplifier.

Abstract: Example embodiments include a radio frequency (RF) transmit system for a digital RF current source, the system including a magnetic resonance imaging (MRI) system control console operably connected to at least one digital RF current source amplifier. The at least one digital RF current source amplifier is operably connected to an RF transmission coil. The MRI system control console provides a digital control signal to the at least one digital RF current source amplifier. The MRI system control console provides a master RF current source clock signal to the at least one digital RF current source amplifier. The digital RF current source amplifier provides an alternating current to the RF transmission coil.

Abstract: Methods and other embodiments control a member of a plurality of MRI transmit (Tx)/receive (Rx) coil array elements to operate in a resonant Tx mode or in a non-resonant Tx mode. The member of the plurality of MRI Tx/Rx coil array elements, upon resonating with a primary coil at a working frequency, generates a local amplified Tx field based on an induced current in the member of the plurality of MRI Tx/Rx coil array elements. The member of the plurality of MRI Tx/Rx coil array elements includes at least one magnitude/phase control circuit connected in parallel. Upon detecting that the member of the plurality of MRI Tx/Rx coil array elements is operating in resonant Tx mode, embodiments randomly control a member of the at least one magnitude/phase control circuit to vary the magnitude or phase of the local amplified Tx field over a range of magnitudes or phases.

Abstract: A magnetic resonance imaging (MRI) radio frequency (RF) coil comprising an LC circuit including at least one series capacitor, and a decoupling circuit connected in parallel to the LC circuit. The decoupling circuit is configured to decouple the MRI RF coil from one or more other MRI RF coils using passive decoupling upon the production of an induced voltage in the decoupling circuit, or to actively decouple the MRI RF coil from one or more other MRI RF coils upon the insertion of a DC bias into the decoupling circuit. The decoupling circuit includes a pair of fast switching PIN diodes including a first PIN diode connected antiparallel with a second PIN diode, the second PIN diode connected in series with a first capacitor. The decoupling circuit further includes an inductor connected in series with the pair of fast switching PIN diodes and the capacitor.

Abstract: A method of controlling a secondary-side rectifier switch of a flyback converter, can include: detecting a slope parameter of a secondary-side detection voltage along a predetermined direction, where the secondary-side detection voltage is configured to represent a voltage across a secondary winding of the flyback converter; and controlling the secondary-side rectifier switch to turn on when the slope parameter is greater than a slope parameter threshold, and a relationship between the secondary-side detection voltage and the ON threshold meets a predetermined requirement.

Abstract: A magnetic write apparatus has a media-facing surface (MFS) and includes an auxiliary pole, coil(s) and a main pole having a pole tip and a yoke. The pole tip occupies part of the MFS. The yoke has a yoke length measured from the MFS in a yoke direction perpendicular to the MFS. The yoke length is less than four microns. The main pole has a total length in the yoke direction and a width in a cross-track direction. The main pole is continuous along the total length. The aspect ratio of the main pole is the total length divided by the width and exceeds one. The main pole includes surface(s) having a nonzero acute flare angle from the MFS. The auxiliary pole is adjacent to the main pole and recessed from the MFS by not more than 1.05 micron. The coil(s) energizes the main pole and have not more than two turns.

Abstract: A control circuit can include: an output current sampling circuit configured to sample a current through a power switch of a switching power supply operating in a quasi-resonant mode, and to generate an output current feedback signal that represents an output current of the switching power supply; and a valley locking circuit configured to receive the output current feedback signal and a plurality of valley switching threshold voltages, where the valley locking circuit is switched to a corresponding valley from a valley currently being locked when the output current feedback signal is increased or reduced to one of the plurality of valley switching threshold voltages.

Abstract: An authorization method for a smart TV is provided. When an application is to be activated, it is determined whether machine authorization information is stored. When the machine authorization information is stored, a client certificate corresponding to the application is searched for. When the client certificate is found, it means the application is authorized. The application authorized by a server can then be activated.

Abstract: A magnetic write apparatus has a media-facing surface (MFS) and includes an auxiliary pole, coil(s) and a main pole having a pole tip and a yoke. The pole tip occupies part of the MFS. The yoke has a yoke length measured from the MFS in a yoke direction perpendicular to the MFS. The yoke length is less than four microns. The main pole has a total length in the yoke direction and a width in a cross-track direction. The main pole is continuous along the total length. The aspect ratio of the main pole is the total length divided by the width and exceeds one. The main pole includes surface(s) having a nonzero acute flare angle from the MFS. The auxiliary pole is adjacent to the main pole and recessed from the MFS by not more than 1.05 micron. The coil(s) energizes the main pole and have not more than two turns.

Abstract: A method for manufacturing an array substrate includes: forming a first conductive pattern and a second conductive pattern on a base substrate; forming a via hole on the base substrate formed with the first conductive pattern and the second conductive pattern, and a lateral side of the via hole being half opened; and forming a jumper wire film on the base substrate formed with the via hole.

Abstract: A method provides magnetic write apparatus. A side shield location layer having a location corresponding to the side shield(s) and back and side surfaces is provided. Part of the back surface corresponds to the back surface of the side shield. A nonmagnetic layer adjoining the back and side surface(s) of the side shield location layer is provided. A pole trench is formed in the layers using a first etch process. The nonmagnetic and side shield location layers have an etch selectivity of at least 0.9 and not more than 1.1 for the first etch. A pole is provided in the pole trench. A remaining portion of the side shield location layer is removed using a wet etch. The nonmagnetic layer is nonremovable by the wet etch. Side shield(s) having a back surface substantially the same as the back surface of the side shield location layer are provided.

Abstract: An embodiment of the present invention provides a manufacturing method of an array substrate comprising forming a gate detecting pattern on the array substrate with gate lines and common electrode lines formed thereon, the gate detecting pattern being arranged on one side of a pixel region of the array substrate and used to connect all the common electrode lines for pixel units; and performing a short circuit or a open circuit detection, wherein if the difference between a signal received by a receiving terminal for a gate line and a signal transmitted from a transmitting terminal for the gate line is larger than a predetermined detection threshold value, it is determined that short circuit between the gate line and a common electrode line or open circuit in the gate line occurs.

Abstract: Example magnetic resonance imaging (MRI) radio frequency (RF) coils are described. An MRI RF coil may include a first terminal and a second terminal that are connected by a coaxial cable. Rather than rely exclusively on two terminal passive components (e.g., resistor, inductor, capacitor), example coax MRI RF coils rely on the capacitance that can be created in the coax cable between the inner conductor and the outer conductor. The capacitance of the coil may be controlled by selectively disrupting (e.g., cutting, stripping) the outer conductor, the inner conductor, or the dielectric material disposed between the inner and outer conductor.

Abstract: An array substrate and manufacturing method thereof, a display device are provided. The array substrate includes a display region and a non-display region; the non-display region includes a first laminated structure and a second laminated structure that are separately disposed on a base substrate, a gap between the first laminated structure and the second laminated structure constitutes a connecting hole; the first laminated structure includes a first via hole provided for exposing a first metal layer, the second laminated structure includes a second via hole provided for exposing a second metal layer, the first via hole and the second via hole are connected to a connecting hole via breaches on corresponding walls, and the first metal layer and the second metal are electrically connected with a conductive film.