Abstract: Antibodies and antigen-binding fragments thereof that bind type II transmembrane serine protease 6 (TMPRSS6) on the surface of a cell and increase hepcidin expression, and methods for treating disorders of iron metabolism using anti TMPRSS6 antibodies and fragments, are provided.

Abstract: Disclosed herein, in certain embodiments, are compositions, solutions, and soft gelatin capsules comprising 17-alpha hydroxyprogesterone caproate (17-HPC). In certain embodiments, also disclosed herein are methods, dosing regimens, and kits for use in the treatment of a disease or condition.

Abstract: A prediction method for charging loads of electric vehicles with consideration of data correlation includes: collecting historical data of the charging loads of the electric vehicles; carrying out data correlation analysis on the historical data of the charging loads of the electric vehicles, and real-time data, and calculating correlation coefficients between the historical data of the charging loads of the electric vehicles and the real-time data; based on the correlation coefficients, selecting historical data of the charging loads of the electric vehicles, which has high correlation, as data of the charging loads of the electric vehicles, which is used for prediction; and predicting the historical data of the charging loads of the electric vehicles, serving as the data of the charging loads of the electric vehicles, which is used for prediction, by adopting an LSTM algorithm, to obtain prediction results.

Abstract: A method for optimizing dispatching of charging loads of electric vehicles to promote wind power consumption includes: acquiring blocked electric quantity of wind power at a peak down-regulation period; acquiring a curve of disorderly charging loads of the electric vehicles; establishing a model for optimizing the charging loads of the electric vehicles to promote wind power consumption, wherein an objective function of the model refers to that the electric vehicles participate in wind power consumption to minimize the remaining blocked quantity of the wind power, and the total charging cost of the electric vehicles is lowest, and acquiring constraint conditions of the model; and solving the optimization model by adopting an adaptive mutation particle swarm optimization algorithm, to obtain the target charging/discharging electric quantity and the target charging/discharging power of the electric vehicles.

Abstract: Antibodies and antigen-binding fragments thereof that bind C1s and inhibit C1s activity and modulate the activity of at least one component in the classical pathway (CP) of complement activation, and methods for treating complement-mediated disorders using anti-C1s antibodies and fragments, are provided.

Abstract: The present application provides a use of hydroxyprogesterone caproate for treating multiple diseases that cause a cytokine storm, such as novel coronavirus pneumonia, various virulent virus infections, side effects after monoclonal antibody treatment, side effects after CAR-T treatment, inflammatory bowel disease, and acute pancreatitis. Moreover, the present application also provides a method for treating the diseases by using a corresponding pharmaceutical composition. Experimental results show that progestin hydroxyprogesterone caproate can effectively inhibit the cytokine storm and is expected to be an effective drug for treating diseases such as novel coronavirus pneumonia.

Abstract: A sealing method for a drilled hole in three zones of overburden comprises: blocking the fissure zone and the caving zone with at least one filling bag; and transporting prepared cement slurry to the drilled hole through a hollow drill pipe, so as to block the curved subsidence zone. The three zones of overburden comprise a fissure zone, a caving zone and a curved subsidence zone.

Abstract: A quadrifilar helix antenna may comprise a cylindrical body with a conductive layer. The antenna may further comprise a first slot disposed on the cylindrical body, wherein a length of the first slot is proportional to a first wavelength of a first signal. The antenna may further comprise a second slot disposed on the cylindrical body. The antenna may further comprise a first feed line crossing the first slot. The antenna may further comprise a second feed line crossing the second slot.

Abstract: A quadrifilar helix antenna may comprise a cylindrical body with a conductive layer. The antenna may further comprise a first slot disposed on the cylindrical body, wherein a length of the first slot is proportional to a first wavelength of a first signal. The antenna may further comprise a second slot disposed on the cylindrical body. The antenna may further comprise a first feed line crossing the first slot. The antenna may further comprise a second feed line crossing the second slot.

Abstract: Disclosed is a method and a composition for inhibiting cytokine storm in a subject in need thereof, in particular cytokine release from PBMCs induced by anti-CD28 antibody and/or anti-CD3 antibody, comprising administering progestogen to the subject. The results show that hydroxyprogesterone caproate could inhibit various cytokines release from PBMC induced by anti-CD28 antibody and/or anti-CD3 antibody in a concentration-dependent manner, and could be a potential drug for the treatment of cytokine storm.

Abstract: A hybrid antenna structure with a ground plane; a supporting body coupled to the ground plane. The supporting body provided with four helical filar extending from the ground plane, ends of each of the filar coupled at a connection point to a periphery of a patch. The filar each having a length of approximately ½ wavelength of a desired operating frequency. Further, the hybrid antenna structure may be configured for self-diplexing by adding a high-band patch upon the patch, spaced apart by a dielectric spacer.

Abstract: Provided herein are antibodies that specifically bind to MICA/B having heavy chain, light chain, variable heavy chain domains (VH), variable light chain domains (VL), and complementarity determining regions (CDRs) disclosed herein, as well as methods and uses thereof.

Abstract: A hybrid antenna structure with a ground plane; a supporting body coupled to the ground plane. The supporting body provided with four helical filar extending from the ground plane, ends of each of the filar coupled at a connection point to a periphery of a patch. The filar each having a length of approximately ½ wavelength of a desired operating frequency. Further, the hybrid antenna structure may be configured for self-diplexing by adding a high-band patch upon the patch, spaced apart by a dielectric spacer.

Abstract: Provided herein are antibodies that specifically bind to MICA/B having variable heavy chain domains (VH), variable light chain domains (VL), and complementarity determining regions disclosed herein, as well as methods and uses thereof

Abstract: The disclosure relates to 433 MHz solid state microwave heating cavity and industrial defrosting system. The 433 MHz solid state microwave heating cavity and industrial defrosting system includes a sample conveying device, a metal detector, a microwave processing system, and a motor, provided on a machine frame. An upper part and a bottom part of a microwave processing module are provided with a microwave source separately. Microwave sources are connected to bell mouths through wave guide tubes. Two bell mouths are connected to a heating cavity through microwave windows. The microwave source is a 433 MHz solid-state microwave source. The high-power-density 433 MHz microwave is used to penetrate meat products to make a uniform temperature inside and outside after defrosting, the defrosting takes only 2-4 minutes from ?18° C. to ?2° C., color and nutrients of the meat products after the defrosting are basically the same as those of fresh meat.

Abstract: An energy harvesting system can comprise an actuator comprising a translationally displaceable surface, the translationally displaceable surface being configured to transition from a first position to a second position upon contact by a movable unit; a vertical rack in contact with the actuator, and configured to be translationally displaced in response to translational displacement of the actuator; a pinion configured to engage with the vertical rack and to rotate in response to translational displacement of the vertical rack; a main shaft coupled to the pinion and configured to rotate with rotation of the pinion; and a flywheel and a generator coupled to the main shaft, wherein rotation of the main shaft generates mechanical energy stored by the flywheel, and wherein the generator is configured to generate electrical energy from the mechanical energy stored by the flywheel.

Abstract: Provided herein are ERFE fusion polypeptides, compositions and methods of use for treatment, for example in treatment of iron metabolism disorders.

Abstract: Provided herein are ERFE specific antibodies, compositions and methods of use for detection of ERFE polypeptides.

Abstract: A calibration method includes forming an external optical path, forming an internal optical path, and conducting a phase comparison between the second part of signals of the internal and external optical paths sequentially received by a second receiving device and the first part of signals of the internal and external optical paths sequentially received by a first receiving device. Two-way phase signals are outputted with part of a base reference being eliminated. Phase comparison is conducted again between the two-way signals with part of the base reference being eliminated, and the final phase signal is outputted with the base reference being eliminated. The distance-measuring device includes a transmitting device, first reflective surface, first and second receiving devices, first and second filters, and a phase detector.

Abstract: Embodiments of the present invention disclose a radial distortion parameter acquiring method and apparatus. The method includes: randomly selecting a plane as a first plane; making an optical axis of a digital image capture device perpendicular to the first plane, and photographing the first plane to obtain a distorted image of the first plane; acquiring n arcs from the distorted image; and obtaining, by calculation, a radial distortion parameter of the digital image capture device according to the arcs. The apparatus includes: a selecting unit, a photographing unit, an acquiring unit, and a calculating unit. By applying the embodiments of the present invention, only one distorted image needs to be photographed to acquire a radial distortion parameter of a digital image capture device, and the distorted image can be acquired depending on a natural environment.