Abstract: A low-dropout regulator, including: a dynamic pole tracking circuit having an active load, a voltage-to-current converter, a current amplifier, a bias circuit, a regulating transistor, a first feedback resistor, a second feedback resistor, and a first capacitor. The dynamic pole tracking circuit includes: a first PMOS, a second PMOS, a first resistor, and a second resistor. The voltage-to-current converter includes: a first NMOS, a second NMOS, a third NMOS, a fourth NMOS, a fifth NMOS, a sixth NMOS, a seventh NMOS, an eighth NMOS, a third PMOS, a fourth PMOS, a seventh PMOS, an eighth PMOS. The current amplifier includes: a fifth PMOS, a sixth PMOS, a ninth NMOS, a tenth NMOS, and a third resistor. The bias circuit includes: a ninth PMOS, a tenth PMOS, an eleventh PMOS, an eleventh NMOS, a twelfth NMOS, a thirteenth NMOS, and a fourth resistor.

Abstract: A low-dropout regulator, including: a dynamic pole tracking circuit having an active load, a voltage-to-current converter, a current amplifier, a bias circuit, a regulating transistor, a first feedback resistor, a second feedback resistor, and a first capacitor. The dynamic pole tracking circuit includes: a first PMOS, a second PMOS, a first resistor, and a second resistor. The voltage-to-current converter includes: a first NMOS, a second NMOS, a third NMOS, a fourth NMOS, a fifth NMOS, a sixth NMOS, a seventh NMOS, an eighth NMOS, a third PMOS, a fourth PMOS, a seventh PMOS, an eighth PMOS. The current amplifier includes: a fifth PMOS, a sixth PMOS, a ninth NMOS, a tenth NMOS, and a third resistor. The bias circuit includes: a ninth PMOS, a tenth PMOS, an eleventh PMOS, an eleventh NMOS, a twelfth NMOS, a thirteenth NMOS, and a fourth resistor.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: Methods of administering an oligonucleotide of interest into a cell in vitro or in vivo are described. In the methods, a small organic compound active agent is concurrently administered to the cell in an amount effective to increase the delivery of the oligonucleotide into the cell, and/or increase the activity of said oligonucleotide in the cell. Compositions useful for carrying out the method are also described.

Abstract: Drug carriers, methods of synthesizing, and methods of use thereof are provided. The drug carriers are liposomes comprising at least one functionalized cholesterol of the formula: Chol-X-T, wherein X is a linker domain, T is at least one targeting moiety which binds hard tissue and/or medical implants, and Chol is cholesterol or a derivative or analog thereof. The liposomes may encapsulate at least one therapeutic agent for the treatment of an oral disease or disorder.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: Compositions and methods for targeting agents to hard tissue are provided.

Abstract: The present invention provides compositions and methods for the delivery of antivirals to a cell or subject.

Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.

Abstract: Tunable nanoparticles and methods of use thereof are provided. In accordance with the instant invention, tunable nanoparticles comprising a metal nanoparticle core (e.g., a paramagnetic particle (e.g., USPIO) or a quantum dot) and a polymer linked to a metal binding moiety are provided. The polymer of the nanoparticle is bound to the metal nanoparticle core by the metal binding moiety and coats the metal nanoparticle core. In a particular embodiment, the metal binding moiety comprises bisphosphonate, pyrophosphate, or a derivative thereof. In a particular embodiment, the polymer is a hydrophilic polymer, an amphiphilic block copolymer or an ionic block copolymer.

Abstract: An arc surface milling machine includes a worktable, a base and a backup plate. The worktable is assembled adjacent to the base. The backup plate is adjustably mounted on the base and positioned adjacent to the worktable. The worktable includes a work surface, an opposite bottom surface, and a mounting end. The base is assembled to the mounting end of the worktable. The work surface defines a concave wedge-shaped receiving space adjacent to the mounting end and forms a milling opening communicating with the work surface and the mounting end.

Abstract: The present invention provides a driving circuit, a backlight module and a display apparatus using the same. The driving circuit comprises a first inductor, a second inductor, a first power switch, a second power switch, a driving circuit unit and a push-pull circuit. The first inductor and the second inductor are connected between the light-emitting diodes and a power supply. The first power switch is connected between the first inductor and the light-emitting diodes. The second power switch is connected between the second inductor and the light-emitting diodes. The push-pull circuit is connected to the first power switch and the second power switch. The driving circuit unit is connected to the push-pull circuit. An electrolytic capacitor or a capacitor having high capacitance can be omitted in this invention.

Abstract: A boost circuit for an LED (Light Emitting Diode) backlight driver circuit is disclosed; said boost circuit includes a PWM (Pulse Width Modulation) chip, a second capacitor, and a signal processing circuit. A VCC pin of the PWM chip is coupled to the input node, and the PWM chip is utilized to generate a PWM signal. One end of the second capacitor is coupled to an output pin of the PWM chip, and the second capacitor is utilized to filter out a direct current component of the PWM signal. One terminal of the signal processing circuit is coupled to the second capacitor, and another terminal thereof is coupled to a gate of the switch. The signal processing circuit is used to adjust the filtered PWM signal for generating corresponding high levels and low levels. A regulator is omitted in the present invention, therefore reducing costs.

Abstract: The present invention provides a self-driven synchronous rectification boost converter having high step-up ratio. The self-driven synchronous rectification boost converter having high step-up ratio has a first switch receiving a pulse driving signal, a first winding, a second winding and a synchronous rectification circuit constructed by an auxiliary winding and a second switch. The first winding inducts a reverse voltage when the first switch is repeatedly switched on and off. The reverse voltage then is raised via the second winding, and the auxiliary winding cooperates with a switch circuit to switch on/off the second switch according to an inducted voltage, so as to achieve an object of synchronous rectification. Under a condition of outputting high current, the present invention can greatly reduce power-consumption of rectifying and enhance efficiency.

Abstract: The present invention provides a self-driven synchronous rectification boost converter. The self-driven synchronous rectification boost converter has a first switch receiving a pulse driving signal, a first winding and a synchronous rectification circuit constructed by an auxiliary winding and a second switch. The first winding stores energy when the first switch is switched on and releases energy when the first switch is switched off to achieve boosting. In the meantime, the auxiliary winding cooperates with a switch circuit to switch on/off the second switch according to a voltage inducted from the first winding, so as to achieve an object of synchronous rectification. Under a condition of outputting high current, the present invention can greatly reduce power-consumption of rectifying and enhance efficiency.

Abstract: The present invention provides a display device and an LED backlight driving circuit thereof. The LED backlight driving circuit includes a plurality of LED light strings connected in parallel; a switch module including switches; a power module, and a switching control module. The switching control module includes: a driving unit connected to the switches; a current detection unit connected to the switches; an ON time detection unit connected to the driving unit; a reference unit, the reference unit supplying a reference value; multipliers, each of which has two input terminals respectively connected to the ON time detection unit and the current detection unit to receive a ON time value of a corresponding one of the switches and a voltage signal indicating the current of the switch; and comparison units, each of which has two input terminals respectively connected to the reference unit and an output terminal of a corresponding one of the multipliers.

Abstract: The present invention provides compositions and methods for the delivery of therapeutics to a cell or subject.