Patents by Inventor Xin Ye

Xin Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210164772
    Abstract: A two-degree-of-freedom heterodyne grating interferometry measurement system, comprising: a single-frequency laser device for emitting a single-frequency laser, and the single-frequency laser can be split into a beam of reference light and a beam of measurement light; an interferometer mirror group and a measurement grating for forming a reference interference signal and a measurement interference signal from the reference light and the measurement light; and a receiving optical fiber for receiving the reference interference signal and the measurement interference signal, wherein a core diameter of the receiving optical fiber is smaller than a width of an interference fringe of the reference interference signal and the measurement interference signal, so that the receiving optical fiber receives a part of the reference interference signal and the measurement interference signal.
    Type: Application
    Filed: June 26, 2019
    Publication date: June 3, 2021
    Inventors: Yu ZHU, Ming ZHANG, Leijie WANG, Fuzhong YANG, Rong CHENG, Xin LI, Weinan YE, Jinchun HU
  • Patent number: 10996153
    Abstract: The present invention relates to a corrosion-fatigue-coupled test method and device for a steel bridge deck. The method includes: 1) installing an orthotropic steel bridge deck (OSBD) and pasting filter paper; 2) installing a sodium chloride solution delivery pipe; 3) installing an infrared (IR) lamp; 4) preparing a corrosive solution; 5) coupling corrosion and fatigue; and 6) acquiring test data. A device constructed by using the method includes a to-be-tested OSBD, a support device, a pressure pump, a water tank, a monitoring device, an IR lamp, a plastic water pipe, a thermostat and a rotary sprayer. The present invention solves the problem of laboratory accelerated corrosion of the OSBD. The present invention fully considers a coupling effect of a corrosive medium and an alternating stress, so that the created simulation environment is close to a service environment of the OSBD, and the test data are effective and reliable.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: May 4, 2021
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Xiaowei Ye, Zhiwen Chen, Xin Qian, Yuliang He
  • Publication number: 20210127268
    Abstract: A method is disclosed; the method may comprise: receiving, at each of a plurality of network computers, a security message from a gateway computer, wherein the security message identifies a current mode of the vehicle, wherein the current mode is indicative of a vehicle state; storing the current mode; receiving a data message; and based on the current mode, determining whether to accept the data message.
    Type: Application
    Filed: October 24, 2019
    Publication date: April 29, 2021
    Applicant: Ford Global Technologies, LLC
    Inventors: Humberto Eduardo Franyie Quintana, Daniel Aaron Zajac, Jiguo Song, Xin Ye
  • Publication number: 20210119271
    Abstract: Embodiments of this application relate to the field of circuit technologies. A wake-up circuit and a rechargeable device are disclosed. The wake-up circuit includes an input control module, a drive module, and an output control module. The input control module, the drive module, and the output control module each are connected to an auxiliary power supply. The input control module is configured to output a first level signal when an external voltage signal is received. The drive module is configured to, when the first level signal is received, output a second level signal that lasts for a first preset time. The output control module is configured to, when the second level signal is received, output a wake-up signal that lasts for the first preset time to a battery management system. According to this application, the wake-up circuit and the BMS consume less power of the auxiliary power supply.
    Type: Application
    Filed: December 24, 2020
    Publication date: April 22, 2021
    Inventors: Xin He, Zhiwei Yan, Fupeng Cai, Lidan Yan, Fuming Ye, Fangjie Zhou
  • Publication number: 20210106655
    Abstract: An interleukin 15 (IL-15) protein complex is provided. The IL-15 protein complex includes soluble fusion proteins (I) and (II), wherein the fusion protein (I) is an IL-15 polypeptide or a functional fragment thereof, and the soluble fusion protein (II) is an IL-15R? polypeptide or a functional fragment thereof. The soluble fusion protein (I) has at least one amino acid residue mutated to a cysteine (Cys) residue, which pairs with a corresponding mutated Cys residue on the soluble fusion protein (II), or vice versa, to form one or more disulfide bonds. The IL-15 protein complex can be used for tumor therapy.
    Type: Application
    Filed: December 21, 2020
    Publication date: April 15, 2021
    Inventors: Xiangdong QU, Xin YE, Qiyue HU, Dongbing CUI, Weikang TAO, Lianshan ZHANG, Piaoyang SUN
  • Publication number: 20210101984
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventors: Jinming GU, Xiaohua WANG, Xin YE, Liuqing YANG, Ting ZHANG, Weikang TAO, Lianshan ZHANG
  • Patent number: 10905743
    Abstract: An interleukin 15 (IL-15) protein complex is provided. The IL-15 protein complex includes soluble fusion proteins (I) and (II), wherein the fusion protein (I) is an IL-15 polypeptide or a functional fragment thereof, and the soluble fusion protein (II) is an IL-15R? polypeptide or a functional fragment thereof. The soluble fusion protein (I) has at least one amino acid residue mutated to a cysteine (Cys) residue, which pairs with a corresponding mutated Cys residue on the soluble fusion protein (II), or vice versa, to form one or more disulfide bonds. The IL-15 protein complex can be used for tumor therapy.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: February 2, 2021
    Inventors: Xiangdong Qu, Xin Ye, Qiyue Hu, Dongbing Cui, Weikang Tao, Lianshan Zhang, Piaoyang Sun
  • Patent number: 10899837
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: January 26, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Jinming Gu, Xiaohua Wang, Xin Ye, Liuqing Yang, Ting Zhang, Weikang Tao, Lianshan Zhang
  • Publication number: 20210008543
    Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.
    Type: Application
    Filed: July 14, 2019
    Publication date: January 14, 2021
    Applicant: Zhuhai Sanmed Biotech LTD
    Inventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
  • Publication number: 20210008566
    Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.
    Type: Application
    Filed: July 14, 2019
    Publication date: January 14, 2021
    Applicant: Zhuhai Sanmed Biotech LTD
    Inventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
  • Publication number: 20210008565
    Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.
    Type: Application
    Filed: July 14, 2019
    Publication date: January 14, 2021
    Applicant: Zhuhai Sanmed Biotech LTD
    Inventors: Behrad Vahidi, William M. Strauss, Mike Trejo, Xin Ye, Dongwen Li
  • Publication number: 20200407724
    Abstract: The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
    Type: Application
    Filed: April 10, 2018
    Publication date: December 31, 2020
    Applicant: ARBUTUS BIOPHARMA CORPORATION
    Inventors: James HEYES, Richard J. HOLLAND, Adam JUDGE, Amy C. H. LEE, Alan D. MARTIN, Nicholas Michael SNEAD, Emily P. THI, Mark WOOD, Xin YE
  • Patent number: 10834199
    Abstract: A vehicle includes a controller, programmed to responsive to receiving a command from a non-customer party, send an authorization request based on the command and a predefined vehicle parameter to a server; and responsive to receiving a signed command from the server, execute the signed command.
    Type: Grant
    Filed: September 18, 2018
    Date of Patent: November 10, 2020
    Assignee: Ford Global Technologies, LLC
    Inventors: Karl Nathan Clark, Jason Michael Miller, Xin Ye, James Michael Weinfurther, Vijayababu Jayaraman
  • Patent number: 10832475
    Abstract: The present disclosure provides a method for constructing a three-dimensional solid model with a geometric error and a computer-readable storage medium. The method includes: S10: obtaining an ideal geometric solid model of a component; S20: constructing a geometric error model for a surface of the component by use of geometric error data of the surface of the component; and S30: replacing a corresponding surface in the ideal geometric solid model with the geometric error model to obtain a three-dimensional solid model with a geometric error. The method for constructing a three-dimensional solid model provided by examples of the present disclosure integrates a geometric error of a component with a CAD model, so as to obtain a three-dimensional solid model with a geometric error, which describes a regular appearance characteristic of a real surface of the component macroscopically, and also reflects an irregular geometric error shape characteristic of the surface of the component microscopically.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: November 10, 2020
    Assignee: BEIJING INSTITUTE OF TECHNOLOGY
    Inventors: Zhijing Zhang, Xin Jin, Zhongqing Zhang, Xin Ye, Qiushuang Zhang
  • Patent number: 10793643
    Abstract: The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and a medicinal application thereof. Provided in the invention is a chimeric antibody and a humanized antibody, both comprising a CDR of the PCSK9 antibody, and a pharmaceutical composition comprising the PCSK9 antibody and an antigen-binding fragment thereof, and an application of the PCSK9 antibody as a lipid-lowering agent. The invention specifically relates to an application of a humanized PCSK9 antibody for preparing a pharmaceutical drug to treat a PCSK9-induced disease or symptom.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: October 6, 2020
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Xiangdong Qu, Xin Ye, Shaoyu Xu, Bei Yuan, Dongbing Cui, Qiyue Hu, Lei Zhang, Zhibin Xu, Weikang Tao, Lianshan Zhang, Piaoyang Sun
  • Patent number: 10791125
    Abstract: A first electronic control unit (ECU) is in communication with a second ECU over a vehicle bus. The first ECU is configured to generate functional safety values and security protection values for a message, validate the security protection values for the message, and send the message to the second ECU including the security protection values but not the functional safety values.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: September 29, 2020
    Assignee: Ford Global Technologies, LLC
    Inventors: Majed Samhan Mohammed, Xin Ye, James Martin Lawlis, Stephen Robert Traicoff
  • Publication number: 20200296007
    Abstract: Systems and methods provide for enriching flow data to analyze network security, availability, and compliance. A network analytics system can capture flow data and metadata from network elements. The network analytics system can enrich the flow data by in-line association of the flow data and metadata. The network analytics system can generate multiple planes with each plane representing a dimension of enriched flow data. The network analytics system can generate nodes for the planes with each node representing a unique value or set of values for the dimensions represented by planes. The network analytics system can generate edges for the nodes of the planes with each edge representing a flow between endpoints corresponding to the nodes. The network analytics system can update the planes in response to an interaction with the planes or in response to a query.
    Type: Application
    Filed: March 14, 2019
    Publication date: September 17, 2020
    Inventors: Matthew Lawson Finn, II, Alok Lalit Wadhwa, Navindra Yadav, Jerry Xin Ye, Supreeth Rao, Prasannakumar Jobigenahally Malleshaiah, Tapan Shrikrishna Patwardhan, Umamaheswaran Arumugam, Aiyesha Ma, Darshan Shrinath Purandare
  • Patent number: 10761812
    Abstract: The present disclosure generally describes computer-implemented methods, program products, and systems for providing an integrated visual code editor that generates code snippets based on input received through the graphical user interface and simultaneously displaying the generated code snippets along with a real-time preview of the runtime behavior of the code snippet through a graphical user interface. The method and system includes a novel graphical user interface of the visual code editor that is connected to a repository and can retrieve information for concurrently display to a developer of the application. The visual code editor may concurrently display a code snippet in particular area of the graphical user interface and the runtime behavior of the code snippet within another area of the graphical user interface.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 1, 2020
    Assignee: SAP SE
    Inventors: Thomas Zang, Xin Ye
  • Publication number: 20200270365
    Abstract: The present invention provides a PCSK9 antibody, an antigen-binding fragment thereof, and medical uses thereof.
    Type: Application
    Filed: December 26, 2016
    Publication date: August 27, 2020
    Inventors: Xiangdong QU, Xin YE, Houcong JIN, Dongbing CUI, Qiyue HU, Weikang TAO, Lianshan ZHANG, Piaoyang SUN
  • Publication number: 20200259108
    Abstract: A display device and a flexible OLED panel. The flexible OLED panel includes: a flexible substrate, and OLED light emitting elements on the substrate. The OLED light emitting elements include pixel circuits and functional layers including anodes disposed above the pixel circuits. The flexible OLED panel further includes pixel unit regions and non-pixel unit regions. The pixel unit regions are arranged in an array, the non-pixel unit regions are disposed between adjacent pixel unit regions. At least one of the anodes, and corresponding transistors in the pixel circuits are located in one pixel unit region, respective transistors in the adjacent pixel unit regions are connected via electrical connection lines, so that the electrical connection lines pass through at least one non-pixel unit region, and a portion of the electrical connection lines in the at least one non-pixel unit region is coated by an organic film layer.
    Type: Application
    Filed: April 2, 2020
    Publication date: August 13, 2020
    Applicant: KunShan Go-Visionox Opto-Electronics Co., Ltd
    Inventors: Zhixiang WANG, Mengfan WANG, Jinku LI, Yang SHEN, Menghua KANG, Xin YE