Abstract: A system includes a control module and a local server. The server is programmed to transmit a command to perform an operation to a plurality of vehicles including a vehicle including the control module. The command including a digital signature that is common across the vehicles. The control module is programmed to receive a temporary value; receive the command; decrypt the digital signature in the command with the temporary value; upon verifying the decrypted digital signature, perform the operation; and upon a metric incrementing to a threshold value, prevent decryption of the digital signature with the temporary value.

Abstract: Provided is a method for processing data, which belongs to the field of Internet technologies. The method includes: providing an item identification function in a live streaming room; acquiring item information based on the item identification function; triggering a server to query a matched target item based on the item information; receiving the target item returned by the server; displaying the target item and a post control in the live streaming room; and adding the target item into an item list of the live streaming room in response to a trigger operation on the post control.

Abstract: Cells in a given population often display heterogeneity that may affect how each cell responds to a particular treatment or growth condition. The methods described herein allow determination of which cells from an initial population survive a treatment or condition, and how surviving cells evolve over time. For example, the methods described herein may be used to model drug resistance, response and/or adaptation in a cell population.

Abstract: Biological research requires isolation and analysis of material, for example, RNA, DNA and protein, from tissue samples. The methods and compositions described herein allow for high resolution imaging of large and intact tissue samples, and subsequent isolation of material in a precise and location dependent-manner. The methods and compositions described herein may be used, for example, for biomarker discovery, identification of cell populations, pathology analysis, and generation of expression data in specific regions of interest.

Abstract: A sewage treatment device includes a fluidized bed body, a reflux device and a chemical feeding device. The fluidized bed body is sequentially provided with a sedimentation zone, a transition zone and a fluidization zone from top to bottom. The reflux device is connected to the fluidized bed body through a reflux pipe. The reflux pipe extends into the fluidized bed body from the sedimentation zone, and the granularity of a crystal product can be controlled by changing the height of a reflux inlet at the bottom end of the reflux pipe in the fluidized bed body. By controlling the position of the reflux inlet of the reflux pipe in the fluidized bed body, combining product granularity requirements, and adjusting an insertion depth of the reflux pipe, the granularity of a final product can be flexibly regulated and controlled, and meanwhile, a product recovery rate is improved.

Abstract: The invention provides certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic double stranded siRNA to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).

Abstract: Provided are a bifunctional fusion protein and pharmaceutical use thereof. Specifically, provided are a bifunctional fusion protein comprising an SIRP? peptide variant and an anti-human PD-L1 antibody, an SIRP? peptide variant, and pharmaceutical use thereof. The bifunctional fusion protein can specifically bind PD-L1 and CD47 to block the binding of PD-L1 or CD47 to a receptor or ligand thereof. In addition, also provided are preparation and application of the bifunctional fusion protein, and treatment of cancers and immune-related diseases.

Abstract: Systems and methods described herein provide for assigning classifications to signals and corresponding messages for prioritization and transmission across a vehicle CAN bus. The assigned classifications are used to select authentication keys specific to each classification of message. Nodes of the CAN bus can include different sets of keys based on the classifications of messages handled at the nodes. Keys are distributed and localized to reduce any potential impact on critical functions of the vehicle system that may result from compromise of an authentication key.

Abstract: Techniques for using a trip flag to detect desynchronization of trip counter values in a vehicle system. Techniques include a first electronic control unit (ECU) receiving a synchronization message including a trip counter and receiving a message from a second ECU including a trip flag. The trip flag includes a single bit of data generated by the second ECU. The first ECU compares the trip flag to a last bit of the trip counter stored at the first electronic control unit and processes the message in response to the trip flag matching the trip counter. The first ECU compares the trip counter to a previous trip counter based on the trip flag differing from the trip counter. The first ECU processes the message using the previous trip counter or increments the trip counter to process the message based on the comparison with the previous trip counter.

Abstract: Provided herein are certain nucleic acids (e.g., double stranded siRNA molecules), as well as conjugates that comprise a targeting moiety, a double stranded siRNA, and optional linking groups. Certain embodiments also provide synthetic methods useful for preparing the conjugates. The conjugates are useful to treat certain diseases, such as liver fibrosis, e.g., in the setting of NASH or ASH.

Abstract: Systems and methods for social networking using augmented reality are disclosed. A network may receive, from a plurality of client devices, a request to connect to a server. The server may be associated with an object, such as a landmark or a product. The server may serialize an AR world including the object and content associated with the object and send, to the plurality of client devices, data indicative of the AR world. The server via network may receive, from a first client device among the plurality of client devices, an indication of user input associated with the AR world. The indication of user input may comprise text data, digital image data, or user feedback. The indication of user input may be broadcast to the plurality of client devices.

Abstract: A sewage treatment device includes a fluidized bed body, a reflux device and a chemical feeding device. The fluidized bed body is sequentially provided with a sedimentation zone, a transition zone and a fluidization zone from top to bottom. The reflux device is connected to the fluidized bed body through a reflux pipe. The reflux pipe extends into the fluidized bed body from the sedimentation zone, and the granularity of a crystal product can be controlled by changing the height of a reflux inlet at the bottom end of the reflux pipe in the fluidized bed body. By controlling the position of the reflux inlet of the reflux pipe in the fluidized bed body, combining product granularity requirements, and adjusting an insertion depth of the reflux pipe, the granularity of a final product can be flexibly regulated and controlled, and meanwhile, a product recovery rate is improved.

Abstract: A computer includes a processor and a memory storing instructions executable by the processor to, upon receiving an authorization message, transmit a plurality of new authentication keys to a respective plurality of control modules, the memory including an expiration time for the authorization message; update a listing of the control modules with respective statuses of the transmissions of the respective new authentication keys to the respective control modules, wherein each status is one of successful or unsuccessful; upon at least one status being unsuccessful, prevent the authorization message from expiring at the expiration time; after preventing the authorization message from expiring, retransmit the respective new authentication keys to each control module for which the respective status is unsuccessful; and then expire the authorization message.

Abstract: A display device and a flexible OLED panel. The flexible OLED panel includes: a flexible substrate, and OLED light emitting elements on the substrate. The OLED light emitting elements include pixel circuits and functional layers including anodes disposed above the pixel circuits. The flexible OLED panel further includes pixel unit regions and non-pixel unit regions. The pixel unit regions are arranged in an array, the non-pixel unit regions are disposed between adjacent pixel unit regions. At least one of the anodes, and corresponding transistors in the pixel circuits are located in one pixel unit region, respective transistors in the adjacent pixel unit regions are connected via electrical connection lines, so that the electrical connection lines pass through at least one non-pixel unit region, and a portion of the electrical connection lines in the at least one non-pixel unit region is coated by an organic film layer.

Abstract: Systems and methods for handling a variety of sample and preparatory fluids in a rack specifically configured for compatibility with predetermined liquid handlers such as automated pipettors or multi-channel manual pipettors and set up for magnetic based sample preparation. The rack can hold all of the necessary sample and reagent vials, and present them to the pipettor in some embodiments in a way that allows for parallel operation. The rack includes slidable magnets that in some embodiments are actuatable directly by the pipettor, eliminating a layer of complexity. Combined with a suitable pipettor the magnet enabled rack supports a multistep magnetic based sample preparation capability in a high throughput manner at one station that enhances sample purity throughout magnetic separation processes.

Abstract: The invention relates to a hot-melt pressure sensitive adhesive composition comprising at least one styrenic block copolymer, at least one tackifying resin, at least one mineral oil and from 4 to 15% by weight of at least one wax selected from the group consisting of paraffin waxes, Fischer-Tropsch waxes, ethylene-vinyl acetate waxes and any mixture thereof, based on the total weight of the hot-melt pressure sensitive adhesive composition. The invention also relates to an article comprising a surface coated with such a hot-melt pressure sensitive adhesive composition, to a use of such a hot-melt pressure sensitive adhesive composition and to a process for preparing such a hot-melt pressure sensitive adhesive composition.

Abstract: Authorization of a user device is suspended based on determining, for a first predetermined time, a distance between the user device and a vehicle is greater than a threshold distance. Then a user input specifying a vehicle parameter is requested. Upon receiving the user input, the user input is validated based on the user input matching a stored vehicle parameter. The user device is deauthorized based on a) failing to receive a valid user input within a second predetermined time, or b) receiving a number of invalid user inputs equal to a threshold number.

Abstract: An onboard communication network of a vehicle is monitored to detect a plurality of available messages that include respective cipher-based message authentication codes (CMAC) and that were identified as eligible messages based on having an information entropy greater than a specified threshold. A first message is selected from the plurality of available messages. The CMAC of the selected message is input into a random number generator that outputs a random number seeded by the CMAC of the selected message. Then the random number is provided.

Abstract: Systems and techniques are described that provide for generalizable approach policy learning and implementation for robotic object approaching. Described techniques provide fast and accurate approaching of a specified object, or type of object, in many different environments. The described techniques enable a robot to receive an identification of an object or type of object from a user, and then navigate to the desired object, without further control from the user. Moreover, the approach of the robot to the desired object is performed efficiently, e.g., with a minimum number of movements. Further, the approach techniques may be used even when the robot is placed in a new environment, such as when the same type of object must be approached in multiple settings.

Abstract: The present application provides an anti-CD38 antibody, an antigen-binding fragment thereof, and pharmaceutical use. Specifically, the present application provides a murine-derived antibody, a chimeric antibody or a humanized antibody comprising a CDR region of the anti-CD38 antibdoy, a pharmaceutical composition comprising the anti-CD38 antibody or the antigen-binding fragment thereof, and an application thereof as a drug. In particular, the present application provides an application of a humanized anti-CD38 antibody in preparing a drug for treating a CD38 positive disease or disorder.