Abstract: The present disclosure relates to a method of preparing a display substrate. The method may include forming a pattern layer on a base substrate; forming a planarization layer on the pattern layer, the planarization layer comprising a host material and a hydrophilic material and a hydrophobic material mixed in the host material; treating the planarization layer so that the host material reacts with the hydrophilic material to form a hydrophilic polymer, the host material reacts with the hydrophobic material to form a hydrophobic polymer, and the planarization layer is delaminated to form a first sub-planarization layer and a second sub-planarization layer; and cleaning the planarization layer with a cleaning solution that reacts with the hydrophobic polymer to remove at least part of the first sub-planarization layer. The first sub-planarization layer includes the hydrophobic polymer, and the second sub-planarization layer includes the hydrophilic polymer.

Abstract: The present application discloses a traffic monitoring method, an apparatus, a device, and a storage medium, relates to fields of autonomous driving, intelligent transportation, big data. The specific implementation is: acquiring road condition information and/or vehicle state information collected by a terminal device, where the terminal device is at least one of an unmanned vehicle and an unmanned aerial vehicle; performing a data analysis on the road condition information and/or the vehicle state information, and identifying a traffic event. Through the above procedure, monitoring efficiency of the traffic state is improved.

Abstract: A color filter substrate, a method of manufacturing the color filter substrate and a display device. The color filter substrate includes a base substrate, and a plurality of color resists on the base substrate, the plurality of color resists having at least two different heights. Roughness of top surfaces of the plurality of color resists is inversely proportional to the heights of the plurality of color resists.

Abstract: Devices, methods, and systems for encoding data as DNA are provided. An encoder device can include an encoder engine configured to encode a data file having a bit sequence encoding data and further configured to generate a virtual DNA (VDNA) sequence of virtual nucleotide bases (Vnb) that reversibly encodes the bit sequence of the data file, divide the VDNA sequence into a plurality of VDNA fragments, associate each VDNA fragment with an archive library sequence (Arc_SEQ), and generate a read instruction (READ) sequence of differences between each VDNA fragment and each associated Arc_SEQ including sufficient instruction to facilitate regeneration of each VDNA fragment from each associated Arc_SEQ. A codeword sequence (Code_SEQ) is additionally generated for each VDNA fragment comprising a codename identifying the associated Arc_SEQ, the READ sequence associated with the VDNA fragment, and an index sequence (Idx_SEQ) including an index mapping of the VDNA fragment in the VDNA sequence.

Abstract: A data interface processing method, device, server and medium are disclosed. The method includes: loading a configuration file when installing the user application, where the configuration file includes a configuration file of a combination relationship between at least one third-party application programming interface and at least one connector, and the connector is used to implement different data conversions between the third-party application programming interfaces. The combination relationship is set according to the requirements of the user application; obtaining, through the user application, user inputs as input parameters; converting, by the user application, the input parameters according to the combination relationship defined in the configuration file and outputting the converted input parameters.

Abstract: Disclosed are a method and an apparatus for analyzing a data flow, a device, and a medium, relating to data processing techniques. The method includes: acquiring, from a resource file corresponding to a web application to be analyzed, javascript code; determining code logic of the javascript code; inserting a probe into the javascript code according to the code logic, wherein the probe is a piece of code; running the resource file with the inserted probe, acquiring, according to the probe, data in a process that the web application implements the code logic through a browser, and recording the data; and analyzing the web application based on the recorded data.

Abstract: An embodiment relates to system comprising: (i) a reaction mixture comprises: a) a target nucleic acid molecule; b) a forward primer complementary to a strand of the target nucleic acid molecule, the forward primer comprises a first molecular moiety at a 3? end, wherein the first molecular moiety is non-complementary to the strand of the target nucleic acid molecule; c) a reverse primer complementary to a complementary sequence of the strand of the target nucleic acid molecule, the reverse primer comprises a second molecular moiety at a 3? end, wherein the second molecular moiety is non-complementary to the complementary sequence of the strand of the target nucleic acid molecule; d) a polymerase with 3?-5? exonuclease activity; and (ii a device suitable of detecting an amplification products.

Abstract: The disclosure provides compositions and methods for amplifying nucleic acids.

Abstract: The invention relates to an integrated tubular reaction device, which comprises a reaction vessel, a reaction vessel including at least two tubular chambers, a channel connecting at least two tubular chambers and an opening; a cover body, which can be worked with the opening, and a cover body including a through hole; a seal, which includes a sealing plug which can be worked with the through hole. The integrated tubular reaction device solves the problem of contamination of reaction products in the process of multiple or multi-step biological enzyme reaction, and can realize multiple or multi-step biological enzyme reactions in the same device.

Abstract: The invention relates to a method and device for amplifying non-purified nucleic acid, where the method comprises the following steps: Providing a reaction device in which an amplification reaction reagent is placed; Sampling with a sampler: the sampler includes a sealing block and a sample needle connected with the sealing block. The end of the sample needle is provided with a hydrophilic surface, which contacts the non-purified nucleic acid sample for sampling; the hydrophilic surface is inserted into the amplification reaction reagent, and the reaction device is sealed by the sealing block; The temperature of the reaction device is controlled by the temperature control instrument to carry out the amplification reaction. The device of the invention is used for realizing the method. The invention can save the process of sample preparation and purification, directly amplify the non-purified sample, reduce the operation difficulty, save the time and reduce the cost.

Abstract: The invention relates to a nucleic acid determination method, which is implemented by the sealed reaction vessel including a tubular chamber and a channel connecting the tubular chamber; the first tubular chamber is provided with the sample and the first set reaction reagent, and the nth tubular chamber is provided with the nth set reaction reagent; the method comprises the following steps: sealing the reaction vessel, conducting the first set of reactions in the first tubular chamber, and the products in the first tubular chamber are transported to the latter tubular chamber through a channel; after the product of the former tubular chamber is transported to the nth tubular chamber, the nth set reaction is carried out in the nth tubular chamber. The nucleic acid determination method provided by the invention can ensure the sealed closed system and convenient and simple operation.

Abstract: DNA synthesis devices, systems, and methods are disclosed. An apparatus can include a synthesizer chip having an array of reaction units in a predetermined pattern, each reaction unit including a reaction surface and a reaction electrode of an IC array of reaction electrodes, and a synthesizer chip controller coupled to the IC array of reaction electrodes configured to address each reaction electrode individually. The apparatus can also include a reagent delivery chip positionable above the synthesizer chip, comprising an array of reagent delivery units arranged in the predetermined pattern, each reagent delivery unit including a reagent electrode of an IC array of reagent electrodes and each reagent delivery unit configured to receive and deliver a droplet of reagent fluid having a volume of 1 picoliter or less, and a reagent delivery chip controller coupled to the IC array of reagent electrodes configured to address each reagent electrode individually.

Abstract: An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

Abstract: Apparatus and methods are disclosed for electrically active combinatorial-chemical (EACC) chips for biochemical analyte detection. An apparatus includes a substrate that has an array of regions defining multiple cells, wherein each of the cells includes a reaction cavity that contains multiple functional binding groups. A method of detecting an analyte providing the reaction cavity between a source and a drain or a pair of electrodes, applying a voltage and monitoring a parameter indicative of an analyte characteristic. A process of fabricating an EACC include bonding an analyte to the multiple functional binding groups of each reaction cavity, and forming an analyte sensing structure including the substrate.

Abstract: A method for matching compound orders from a group of market participants includes receiving, via a communication network, compound order data, the compound order data specifying a maximum amount of a financial instrument of a plurality of financial instruments to be bought or sold by each market participant, accessing a memory in which price data is stored, the price data indicating a current price of each financial instrument, implementing, with a processor, a linear solver to maximize fulfillment of the compound orders via order matching for execution at the current prices in accordance with the maximum amounts specified in the compound order data and in accordance with a maximum net risk exposure level for each market participant arising from the fulfillment of the compound orders, and transmitting trade data indicative of the order matching for execution of trades among the market participants at the current prices.

Abstract: Devices and methods for detecting, identifying, and sequencing, compounds, complexes, and molecules are described. Electronic detection is combined with optical excitation to determine the presence or identity of an analyte of interest. Embodiments of the invention additionally provide devices and methods that allow highly parallel nucleic acid sequence determination.

Abstract: A method for matching compound orders from a group of market participants includes receiving, via a communication network, compound order data, the compound order data specifying a maximum amount of a financial instrument of a plurality of financial instruments to be bought or sold by each market participant, accessing a memory in which price data is stored, the price data indicating a current price of each financial instrument, implementing, with a processor, a linear solver to maximize fulfillment of the compound orders via order matching for execution at the current prices in accordance with the maximum amounts specified in the compound order data and in accordance with a maximum net risk exposure level for each market participant arising from the fulfillment of the compound orders, and transmitting trade data indicative of the order matching for execution of trades among the market participants at the current prices.

Abstract: A color filter substrate, a method of manufacturing the color filter substrate and a display device are provided. The color filter substrate includes a base substrate, and a plurality of color resists on the base substrate, the plurality of color resists having at least two different heights. Roughness of top surfaces of the plurality of color resists is inversely proportional to the heights of the plurality of color resists.

Abstract: Methods, systems, and devices for detecting an analyte are disclosed and described. In one embodiment, a Metal Oxide Semiconductor (MOS) sensor pixel with a MOS active material is exposed to the analyte in the gas environment. The MOS sensor pixel is heated to a sequence of different predetermined temperatures via a heating element wherein the heating occurs for a period of time for each of the different predetermined temperatures. Response signals are detected, via an electrode, generated by the MOS sensor at each of the different predetermined temperatures. The response signals are assembled into sample data with data features for machine learning. The sample data is compared with data in a standards database. A composition of the analyte is identified based on the data features.

Abstract: Devices, methods, and systems for encoding data as DNA are provided. An encoder device can include an encoder engine configured to encode a data file having a bit sequence encoding data and further configured to generate a virtual DNA (VDNA) sequence of virtual nucleotide bases (Vnb) that reversibly encodes the bit sequence of the data file, divide the VDNA sequence into a plurality of VDNA fragments, associate each VDNA fragment with an archive library sequence (Arc_SEQ), and generate a read instruction (READ) sequence of differences between each VDNA fragment and each associated Arc_SEQ including sufficient instruction to facilitate regeneration of each VDNA fragment from each associated Arc_SEQ. A codeword sequence (Code_SEQ) is additionally generated for each VDNA fragment comprising a codename identifying the associated Arc_SEQ, the READ sequence associated with the VDNA fragment, and an index sequence (Idx_SEQ) including an index mapping of the VDNA fragment in the VDNA sequence.