Patents by Inventor Xuejun Zhang
Xuejun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250136382Abstract: Embodiments of the present application provide a method, a system and an apparatus for impurity inspection in a product, a device, a storage medium, and a software product. The method includes: determining a product object to be inspected and placing the product object in an inspection state, performing video capture on the product object in the inspection state from a plurality of different preset capture angles to obtain captured videos of the product object at each of the preset capture angles, performing image processing on the captured video to obtain captured images corresponding to each of the preset capture angles, and performing impurity inspection on the product object according to the captured images corresponding to each of the preset capture angles to generate a corresponding inspection result.Type: ApplicationFiled: January 19, 2023Publication date: May 1, 2025Inventor: Xuejun ZHANG
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Publication number: 20250115613Abstract: The present invention provides a diaryl compound as a tubulin/Src dual target inhibitor. The present invention also provides a diaryl compound represented by formula I, a tautomer, a stereoisomer, a solvate, a pharmaceutically acceptable salt, or a prodrug thereof. The diaryl compound can be used as a dual target inhibitor against tubulin and Src kinase and can also be used as a mono-target inhibitor against tubulin or Src kinase. The compound of the present invention can significantly inhibit the polymerization of tubulin monomers and cell proliferation.Type: ApplicationFiled: January 13, 2023Publication date: April 10, 2025Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyInventors: Xuejun ZHANG, Yang ZANG, Hui YANG, Sijun LEI, Wenjun WEI, Zhiqiang WU, Lifei LIU, Xin ZHANG, Li'e LI, Jun YANG
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Patent number: 12273162Abstract: The present invention discloses a coevolution-based multi-beamforming optimizing method for space-based ADS-B, which belongs to the field of aviation technologies. According to this method, after initializing population and acquiring an initial optimal solution, optimization parameters are firstly grouped randomly so that all beams form several significant uncovered regions. Then, grouping is performed by an adaptive grouping strategy based on the relative orientation between the mean center of the largest uncovered region and the direction of each beam, so that the parameters quickly converge to a full-coverage state within the half angle of the satellite. Finally, grouping is performed by a grouping strategy based on the aircraft density covered by each beam to obtain optimally the minimal update time interval under a full-coverage constraint.Type: GrantFiled: January 17, 2023Date of Patent: April 8, 2025Assignee: Beihang UniversityInventors: Xuejun Zhang, Yuanhao Tan, Xueyuan Li
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Publication number: 20250085714Abstract: The present invention discloses a method for UAV path planning in urban airspace based on a safe reinforcement learning (RL) algorithm called shield-DDPG, which combines a shield model with a DDPG algorithm and pertains to the field of UAV technologies. The method takes an attractive force from the destination point into account when an action is selected, which improves the convergence speed of the algorithm and also improve the efficiency of UAV path planning. More importantly, the method provided by the present invention can effectively verify safety of an action in terms of the air collision risk and the ground impact risk, and ensure that a final output of the algorithm is a safe optimal solution. Therefore, the present invention can effectively solve the problem that when the RL algorithm is used for UAV path planning, it is difficult to ensure the safety of the learning or execution process due to the lack of hard constraints.Type: ApplicationFiled: February 23, 2023Publication date: March 13, 2025Inventors: Xuejun ZHANG, Yan LI, Yuanjun ZHU
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Patent number: 12248327Abstract: The present invention discloses a method for UAV path planning in urban airspace based on a safe reinforcement learning (RL) algorithm called shield-DDPG, which combines a shield model with a DDPG algorithm and pertains to the field of UAV technologies. The method takes an attractive force from the destination point into account when an action is selected, which improves the convergence speed of the algorithm and also improve the efficiency of UAV path planning. More importantly, the method provided by the present invention can effectively verify safety of an action in terms of the air collision risk and the ground impact risk, and ensure that a final output of the algorithm is a safe optimal solution. Therefore, the present invention can effectively solve the problem that when the RL algorithm is used for UAV path planning, it is difficult to ensure the safety of the learning or execution process due to the lack of hard constraints.Type: GrantFiled: February 23, 2023Date of Patent: March 11, 2025Assignee: Beihang UniversityInventors: Xuejun Zhang, Yan Li, Yuanjun Zhu
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Patent number: 12221449Abstract: Provided is a new compound capable of effectively inhibiting ATX. The compound is represented by formula I, or the compound is a tautomer, a stereoisomer, a hydrate, a solvate, a salt, or a prodrug of the compound represented by formula I. In formula (I), R1 and R2 are independently selected from —H or —CH3, provided that: R1 and R2 are not —H at the same time or are not —CH3 at the same time.Type: GrantFiled: January 22, 2020Date of Patent: February 11, 2025Assignee: WUHAN HUMANWELL INNOVATIVE DRUG RESEARCH AND DEVELOPMENT CENTER LIMITED COMPANYInventors: Xuejun Zhang, Dabing Ye, Lie Li, Jie Shen, Xiaohua Ding, Hongna Sun, Zhe Liu, Yang Zang, Yonggang Wei
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Publication number: 20250034134Abstract: Provided are a 15-PGDH inhibitor and the use thereof. The 15-PGDH inhibitor is a heterocyclic compound as represented by formula I, a solvate thereof, a pharmaceutically acceptable salt thereof, a solvate of a pharmaceutically acceptable salt thereof, or a prodrug thereof. The compound has a good inhibitory effect on 15-PGDH.Type: ApplicationFiled: November 18, 2022Publication date: January 30, 2025Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyInventors: Xuejun ZHANG, Xueqiang LI, Hongqiang WANG, Dabing YE, Meng WANG, Dan AN, Zhenxing GAO, Xin ZHAO, Li'e LI, Jun YANG
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Publication number: 20250007571Abstract: The present invention discloses a coevolution-based multi-beamforming optimizing method for space-based ADS-B, which belongs to the field of aviation technologies. According to this method, after initializing population and acquiring an initial optimal solution, optimization parameters are firstly grouped randomly so that all beams form several significant uncovered regions. Then, grouping is performed by an adaptive grouping strategy based on the relative orientation between the mean center of the largest uncovered region and the direction of each beam, so that the parameters quickly converge to a full-coverage state within the half angle of the satellite. Finally, grouping is performed by a grouping strategy based on the aircraft density covered by each beam to obtain optimally the minimal update time interval under a full-coverage constraint.Type: ApplicationFiled: January 17, 2023Publication date: January 2, 2025Inventors: Xuejun ZHANG, Yuanhao TAN, Xueyuan LI
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Publication number: 20250007602Abstract: The present invention discloses a multi-beamforming optimization method for space-based ADS-B based on a coverage matrix. The method includes: calculating signal-to-noise ratios of received signals based on an ADS-B signal model and an air-space channel model; deriving the correct reception probability of ADS-B signals by a satellite with different signal-to-noise ratios and with different numbers of aircraft on the basis of analyzing a correct decoding probability and a collision probability; and in the case that the constraint of satellite coverage metric is satisfied, aiming at minimizing the update interval of position messages at the update probability of 95%, establishing a digital multi-beamforming optimization model for space-based ADS-B.Type: ApplicationFiled: January 17, 2023Publication date: January 2, 2025Inventors: Xuejun ZHANG, Xueyuan LI, Yuanhao TAN
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Patent number: 12145924Abstract: The present invention provides a compound of formula or a pharmaceutical salt thereof, use, methods for its preparation are described.Type: GrantFiled: May 18, 2022Date of Patent: November 19, 2024Assignee: ELI LILLY AND COMPANYInventors: Tianwei Ma, Liang Wu, Xuejun Zhang
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Publication number: 20240381108Abstract: A mining mobile communication system includes a first subsystem configured for communication in a licensed frequency band.Type: ApplicationFiled: February 7, 2023Publication date: November 14, 2024Inventors: Liya Zhang, Chenxin Li, Qingyong Meng, Wenzhen Wu, Liang Wen, Guowei Yang, Yufeng Jiang, Yuan Fu, Biao Li, Chunxian Wei, Kebing Wang, Yongwei Chen, Changjin Lian, Xuejun Zhang, Shouxin Kang, Zefang Li, Xiaodi Jia
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Publication number: 20240368088Abstract: An EP4 antagonist represented by formula I, which specifically comprises a crystal form thereof, a pharmaceutically acceptable salt or crystal form thereof, a preparation method therefor, a composition containing same, and a medical use of a related compound.Type: ApplicationFiled: September 2, 2022Publication date: November 7, 2024Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyInventors: Xuejun ZHANG, Yang YUE, Yang ZANG, Sijun LEI, Qingfeng XIA, Yuan LI, Zhe LIU, Jun YANG, Li'e LI
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Publication number: 20240356411Abstract: The present disclosure relates to an electric motor cooling arrangement including an end oil spray assembly arranged at both ends of a stator of an electric motor, being used to spray cooling oil towards a winding head of the stator to cool the winding head, and a water cooling assembly arranged to surround at least the core part of the stator, wherein cooling water circulates in the water cooling assembly to cool the core part of the stator.Type: ApplicationFiled: April 19, 2024Publication date: October 24, 2024Applicant: Valeo eAutomotive Germany GmbHInventors: Xuejun ZHANG, Wei ZHU, Pengcheng FAN
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Publication number: 20240301648Abstract: Disclosed is a movable foundation static load test apparatus, which includes a rack, a crawler traveling mechanism and a position adjusting mechanism. The rack is configured to place a balancing weight, the crawler traveling mechanism includes a frame fixedly connected with the rack and is configured to drive the rack to travel, the position adjusting mechanism has a movable stroke moving along the vertical direction, the rack has a movable stroke moving along the vertical direction, the position adjusting mechanism is configured to adjust the distance between the rack and a test object. The crawler traveling mechanism drives the rack to travel, after reaching a test point, the distance between the rack and the test object is adjusted by the position adjusting mechanism to carry out a static load test, the rack may be conveniently moved through the crawler traveling mechanism.Type: ApplicationFiled: January 30, 2024Publication date: September 12, 2024Applicant: Guangdong Construction Engineering Quality & Safety Testing Head Station Co., Ltd.Inventors: Shaoxiang CHEN, Wenlong LV, Chaohua LI, Zhonghua PANG, Guangping LI, Zuoping ZHANG, Xuejun ZHANG, Mei YANG, Ming XIAO, Shicong WEN, Sinan DAI, Yongqiao XIE
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Publication number: 20240287064Abstract: The present invention relates to a tricyclic compound used as a GPR84 antagonist, and in particular relates to a tricyclic compound having a structure shown in formula I, and tautomers, stereoisomers, hydrates, solvates, pharmaceutically acceptable salts or prodrugs thereof; the definitions of the ring Cy, L1, R1 are as described in the present invention; the tricyclic compound has significant GPR84 antagonism, good pharmaceutical developability and high safety.Type: ApplicationFiled: June 21, 2022Publication date: August 29, 2024Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyInventors: Xuejun ZHANG, Yang ZANG, Wenjun WEI, Qun LI, Xin ZHAO, Qing XU, Ping NI, Li'e LI, Jun YANG
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Publication number: 20240213836Abstract: A rotor includes a rotor shaft, having a rotation axis; a rotor body, fixed to the rotor shaft and formed of multiple stacked laminations. Magnet mounting grooves are provided in the rotor body, and multiple magnets are disposed in the magnet mounting grooves, with a gap formed between each magnet and an inner wall of the corresponding magnet mounting grooves. First and second end plates are respectively disposed at two ends of the rotor body along the rotation axis. A fluid cooling system includes a slot, disposed on one of the first end plate and second end plate, and located on a side of this end plate that faces towards the rotor body; a through-hole, disposed on the other of the first end plate and second end plate; and the gap. The slot, the gap and the through-hole are in fluid communication to form a cooling medium channel.Type: ApplicationFiled: December 20, 2023Publication date: June 27, 2024Applicant: Valeo eAutomotive Germany GmbHInventors: Pengcheng FAN, Wei ZHU, Xuejun ZHANG, Renlong YING
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Publication number: 20240166645Abstract: A pyridopyrimidinone derivative as represented by formula I, and a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt thereof or a prodrug thereof. The pyridopyrimidinone derivative has a good SOS1 inhibitory effect.Type: ApplicationFiled: February 8, 2022Publication date: May 23, 2024Applicant: Wuhan Humanwell Innovative Drug Research and Development Center Limited CompanyInventors: Xuejun ZHANG, Shaohua CHANG, Xueqiang LI, Dabing YE, Hongqiang WANG, Hongna SUN, Jun YANG, Li'e LI
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Publication number: 20240092046Abstract: The present invention relates to a product forming method, a product, and a shoe. The product forming method comprises the following steps: (1) placing a film on a bottom mold, and fixing the film between the bottom mold and a middle frame; (2) placing an outer housing material on the film, and suctioning the film, so that the film is internally recessed in the direction of the bottom mold, and then performing first curing molding to obtain a molded outer housing; and (3) placing an inner liner material on the molded outer housing, performing second curing molding to obtain a molded inner liner, and demolding to obtain the product.Type: ApplicationFiled: August 3, 2021Publication date: March 21, 2024Inventors: Wu CAI, Yongxin BAO, Wandong CAI, Yebao ZHAO, Xuejun ZHANG, Yu CHI
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Patent number: 11885827Abstract: A high anti-vibration gas density monitor is provided, including a monitor enclosure, a signal control mechanism, and an indication value display mechanism independent from the signal control mechanism which are provided in the monitor enclosure. The signal control mechanism includes at least one corrugated pipe, a sealed compensation chamber, a signal generator, and a signal regulation mechanism. The corrugated pipe is perpendicular to a side wall of a control casing. The monitor enclosure includes an independent sealed compartment used to mount the indication value display mechanism. The sealed compartment is filled with anti-vibration oil, or is hermetically filled with gas. The indication value display mechanism includes a Bourdon tube, a base, an end holder, a movement, a pointer, and a dial.Type: GrantFiled: March 2, 2021Date of Patent: January 30, 2024Assignee: SHANGHAI ROYE ELECTRIC CO., LTD.Inventors: Libo Luo, Xuejun Zhang, Min Chang, Bing He, Xiaoli Shen, Haiyong Jin
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Publication number: 20230399314Abstract: The present disclosure provides a novel compound for effectively inhibiting the activity of CD73, a preparation method thereof, and use thereof in the preparation of drugs, and the novel compound is a compound represented by formula I, or a tautomer, stereoisomer, hydrate, solvate, pharmaceutically acceptable salt, or prodrug thereof.Type: ApplicationFiled: November 5, 2021Publication date: December 14, 2023Applicant: WUHAN HUMANWELL INNOVATIVE DRUG RESEARCH AND DEVELOPMENT CENTER LIMITED COMPANYInventors: Xuejun ZHANG, Shaohua CHANG, Dabing YE, Sijun LEI, Yonggang WANG, Yong LIU, Hongna SUN, Jun YANG, Lie LI