Abstract: A method for reinforcing soft ground by post-grouting combined with pressurized vacuum preloading is proposed, by pre-burying prefabricated vertical drains and air-boosted pipes in granular material piles, and the air-boosted pipes are used as grouting pipes to reduce the number of times of piling, which not only improves the construction efficiency, but also reduces the structural disturbance of the soil and the influence of smear effect, thus reducing the impact on the radial permeability and the radial consolidation coefficients. The method does not use geotextile bags for granular materials, which can avoid the problem of forming a localized clogging area around the geotextile bags, and the method not only improves the efficiency of vacuum transfer in a pre-consolidation stage, but also improves the grouting effect in the later stage, effectively enhances the strength of soft soil and makes granular material piles and the surrounding soil form composite ground.

Abstract: The present disclosure provides a kit and method for constructing a long-acting depression animal model. The present disclosure adopts Bacille Calmette-Guerin (BCG) (or Mycobacterium bovis (M bovis)) and low-dose pertussis toxin (PTX) for combined induction, which greatly reduces modeling cost. A mouse model constructed by the method of the present disclosure can clearly distinguish a time interval of pathological behaviors from a time interval of depression-like behaviors and has prominent face validity and predictive validity. The method of the present disclosure is simple and convenient and does not require a large number of tedious daily operations as the depression model construction by chronic unpredictable stress, chronic restraint stress, social defeat, mother-child separation, or the like. The mouse model of the present disclosure can provide a valuable long-term intervention window for research on antidepressant therapy.

Abstract: An array substrate (100) and a display device. The array substrate (100) includes a bonding area (102). The array substrate (100) includes a substrate (10), a first conductive layer (20) on the substrate (10), a first insulating layer (30) on one side of the first conductive layer (20) away from the substrate (10), and a second conductive layer (40) on one side of the first insulating layer (30) away from the substrate (10). The bonding area (102) is provided with bonding pins (201), and the bonding pin (201) includes a first conductive portion (21) and a second conductive portion (41) located on the side of the first conductive portion (21) away from the substrate (10), the first conductive portion (21) is located in the first conductive layer (20), the second conductive portion (41) is located in the second conductive layer (40), and the first conductive portion (21) is in direct contact with the second conductive portion (41).

Abstract: A ripple push method for a graph cut includes: obtaining an excess flow ef(v) of a current node v; traversing four edges connecting the current node v in top, bottom, left and right directions, and determining whether each of the four edges is a pushable edge; calculating, according to different weight functions, a maximum push value of each of the four edges by efw=ef(v)*W, where W denotes a weight function; and traversing the four edges, recording a pushable flow of each of the four edges, and pushing out a calculated flow. The ripple push method explores different push weight functions, and significantly improves the actual parallelism of the push-relabel algorithm.

Abstract: Provided is a weakly supervised pathological image tissue segmentation method based on an online noise suppression strategy, including: acquiring a hematoxylin-eosin (H&E) stained graph, processing the H&E stained graph to obtain a data set, dividing the data set, training a classification network based on a divided data set, and generating a pseudo-label; suppressing a noise existing in the pseudo-label based on the online noise suppression strategy, and training a semantic segmentation network through the pseudo-label after noise suppression and a training set corresponding to the pseudo-label to obtain a prediction result of the semantic segmentation network after the training, and taking the prediction result as a final segmentation result.

Abstract: Provided are a compound of formula (I), a stereoisomer, a deuterated compound, a solvate, a prodrug, a metabolite, a pharmaceutically acceptable salt or a eutectic thereof, or a pharmaceutical composition comprising same, and use thereof as a ketohexokinase inhibitor in the preparation of drugs for treating related diseases. Each group in formula (I) is as defined in the description.

Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.

Abstract: Coherent optical multiplexing 1+1 protection disclosed herein uses multiplexers, each having multiplexing and demultiplexing sub-units. Relay ports of a node are connected with the multiplexers, and each relay port is configured to input and output optical signals with the corresponding multiplexer. Two transmission ports of the node are connected with disjoint paths and are configured to input and output optical signals therewith. The node includes: a first optical splitter having input ports connected with the relay ports and two output ports connected with the two transmission ports; an optical switch connected with the transmission ports respectively via two input interfaces; a second optical splitter, which is a 1×N optical splitter, having one input port connected with an output interface of the optical switch and having output ports connected with the relay ports. The solution is reliable in implementation, has low insertion loss, and has good transmission performance.

Abstract: The present disclosure provides a substrate, a maintenance method thereof and a display device. The substrate includes a base substrate, the base substrate is provided with at least one conductive pattern, and at least one of the at least one conductive pattern is interrupted and divided into a first conductive sub-pattern and a second conductive sub-pattern. The maintenance method includes: coating a conductive material in an interruption region in such a manner as to cover both the first conductive sub-pattern and the second conductive sub-pattern; and coating an organic insulation material at a side of the conductive material away from the base substrate, and curing the organic insulation material to form an organic protection film covering the conductive material.

Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.

Abstract: The present invention relates to a CPR posture monitoring model and system, the model being configured to: based on human skeleton point data extracted from CPR moves, at least compute arm-posture angle data and GC matching angle data related to the CPR moves, and determine whether the CPR moves are qualified by comparing arm-posture angle data and GC matching angle data to a CCP qualification threshold; wherein human skeleton point data are extracted from first move data collected by a first optical component and second move data collected by a second optical component simultaneously, wherein an included angle between collection directions of the two optical components ranges between 30 and 90 degrees. By constructing and applying a CPR posture monitoring model defined by data like GC matching angle, evaluation result has higher accuracy.

Abstract: Coherent optical multiplexing 1+1 protection disclosed herein uses multiplexers, each having multiplexing and demultiplexing sub-units. Relay ports of a node are connected with the multiplexers, and each relay port is configured to input and output optical signals with the corresponding multiplexer. Two transmission ports of the node are connected with disjoint paths and are configured to input and output optical signals therewith. The node includes: a first optical splitter having input ports connected with the relay ports and two output ports connected with the two transmission ports; an optical switch connected with the transmission ports respectively via two input interfaces; a second optical splitter, which is a 1×N optical splitter, having one input port connected with an output interface of the optical switch and having output ports connected with the relay ports. The solution is reliable in implementation, has low insertion loss, and has good transmission performance.

Abstract: The present disclosure discloses a wheel rim finishing device. A motor is fixedly mounted on a stand through a shaft sleeve I. A supporting body is arranged on the stand. The side, close to a locating disk, of the supporting body is provided with an outer roller. An inner driving roller body and an inner driven roller body are arranged at a position, close to the outer roller, on the inner side of the locating disk. The wheel rim finishing device is simple in structure and high in universality, and may adapt to wheel types with different rim structures.

Abstract: A drive circuit, a drive method, a shift register, and a display device are provided. The drive circuit includes a control module, an output module, and a protect module. The control module is electrically connected to a start signal line, first and second clock signal lines, first and second potential signal lines, and first and second nodes, and is configured to transmit a voltage signal to the first and the second nodes in response to first and second clock signals. The output module is electrically connected to the first and second potential signal lines, an output wire, and the first and second nodes. The protect module is configured to transmit an effective voltage signal to the first node in response to a control signal in a first state of the drive circuit such that the output module transmits an ineffective voltage signal to the output wire.

Abstract: Coherent optical multiplexing 1+1 protection disclosed herein uses multiplexers, each having multiplexing and demultiplexing sub-units. Relay ports of a node are connected with the multiplexers, and each relay port is configured to input and output optical signals with the corresponding multiplexer. Two transmission ports of the node are connected with disjoint paths and are configured to input and output optical signals therewith. The node includes: a first optical splitter having input ports connected with the relay ports and two output ports connected with the two transmission ports; an optical switch connected with the transmission ports respectively via two input interfaces; a second optical splitter, which is a 1×N optical splitter, having one input port connected with an output interface of the optical switch and having output ports connected with the relay ports. The solution is reliable in implementation, has low insertion loss, and has good transmission performance.

Abstract: Disclosed is a nitrile derivative compound represented by formula (I), a stereoisomer, a deuterated product, a co-crystal, a solvate or a pharmaceutically acceptable salt thereof, wherein each group is as defined in the description. The compound has dipeptidyl peptidase 1 inhibitory activity and can be used to prepare a drug for treating diseases including obstructive airway diseases, bronchiectasis, cystic fibrosis, asthma, emphysema, and chronic obstructive pulmonary diseases.

Abstract: A coal mining method is provided without coal-pillar leaving and without laneway excavation in a full mining area. The coal mining method includes drilling a main shaft, an auxiliary shaft and a return air shaft from a ground to a coal mining layer; by a coal mining machine, forming a first mining face with a first direction as an advance direction; by the coal mining machine, cutting out a first haulageway and a first return airway while cutting the coal wall at the first mining face, and preserving the first haulageway and the first return airway. In this method, the first haulageway and the first return airway are located on two sides of the first mining face, the first haulageway is in communication with both of the main and auxiliary shafts, and the first return airway is in communication with the return air shaft.

Abstract: An underground longwall mining method includes drilling a main shaft and an auxiliary shaft from a ground to a coal bed and exploiting in the coal bed first and second connection laneways. The first connection laneway is in communication with the main shaft, and the second connection laneway is in communication with the auxiliary shaft. The method further includes communicating the first and second connection laneways, and using a communication part between the first connection laneway and the second connection laneway as a first open-off cut; and by using a direction of the first open-off cut further away from the connecting line connecting the main shaft and the auxiliary shaft as a first direction, and exploiting by cutting a coal wall in the first direction using a coal mining machine.

Abstract: Coherent optical multiplexing 1+1 protection disclosed herein uses multiplexers, each having multiplexing and demultiplexing sub-units. Relay ports of a node are connected with the multiplexers, and each relay port is configured to input and output optical signals with the corresponding multiplexer. Two transmission ports of the node are connected with disjoint paths and are configured to input and output optical signals therewith. The node includes: a first optical splitter having input ports connected with the relay ports and two output ports connected with the two transmission ports; an optical switch connected with the transmission ports respectively via two input interfaces; a second optical splitter, which is a 1×N optical splitter, having one input port connected with an output interface of the optical switch and having output ports connected with the relay ports. The solution is reliable in implementation, has low insertion loss, and has good transmission performance.