Abstract: The present invention provides methods for analyzing compositions of polypeptides such as antibodies by ionic strength-mediated pH gradient ion exchange chromatography. In some aspects, the methods use a combination of pH gradients and ionic strength gradients to separate the polypeptide from charge variants of the polypeptide. In some aspects, the methods use a stable ionic strength to optimize the pH gradient separation window to separate the polypeptide from charge variants. Such methods are useful for analyzing polypeptide, e.g. antibodies, with a pI greater than 9 or a pI less than 7. In some aspects, the invention provides a multiproduct method for the analysis of polypeptides of varying pI's.

Abstract: Method and apparatus of an optical routing system (“ORS”) capable of automatically discovering intra-nodal fiber connections using a test channel transceiver (“TCT”) are disclosed. ORS, in one embodiment, includes a set of reconfigurable optical add-drop multiplexer (“ROADM”) modules, intra-nodal fiber connections, add-drop modules, and a test module. The ROADM modules are able to transmit or receive optical signals via optical fibers. The intra-nodal fiber connections are configured to provide optical connections. The add-drop modules are able to selectively make connections between input ports and output ports. The test module containing TCT is configured to identify at least a portion of intra-nodal connections of the ROADM via a test signal operating with a unique optical frequency.

Abstract: An intranodal reconfigurable optical add/drop multiplexer (ROADM) fiber management apparatus, and a system employing the apparatus. The apparatus comprises a plurality of ingress optical ports, a plurality of egress optical ports, and a plurality of optical interconnections interposed between ones of the plurality of ingress optical ports and ones of the plurality of egress optical ports. Each of the plurality of ingress optical ports corresponds to one of the plurality of egress optical ports. Each one of the plurality of ingress optical ports is optically coupled by way of the optical interconnections to at least one of the plurality of egress optical ports. Each one of the plurality of egress optical ports is optically coupled by way of the optical interconnections to at least one of the plurality of ingress optical ports.

Abstract: A method for three-dimensional (3D) shape measurement includes generating fringe patterns using a dithering technique, projecting the fringe patterns onto an object using a projector, capturing the fringe patterns distorted by surface geometry of the object using an imaging device, and performing a fringe analysis to reconstruct a 3D shape of the object using the fringe patterns and the fringe patterns distorted by the surface geometry of the object. The step of generating the fringe patterns using the dithering technique may include binarizing sinuisoidal fringe patterns with the dithering technique. The step of generating the fringe patterns using the dithering technique may include applying an optimization algorithm.

Abstract: A method includes obtaining three-dimensional range data, using a computer graphics rendering pipeline to encode the three-dimensional range data into two-dimensional images, retrieving depth information for each sampled pixel in the two-dimensional images, and encoding the depth information into red, green and blue color channels of the two-dimensional images. The two-dimensional images may be compressed using two-dimensional techniques including dithering. The step of obtaining the three-dimensional range data may be performed using a three-dimensional range scanning device. The method may further include storing the two-dimensional images on a computer readable storage medium. The method may further include setting up the viewing angle for the three-dimensional range data. The viewing angle for the three-dimensional range data is a viewing angle of a camera used in obtaining the three-dimensional range data.

Abstract: A method for three-dimensional (3D) shape measurement includes generating fringe patterns using a dithering technique, projecting the fringe patterns onto an object using a projector, capturing the fringe patterns distorted by surface geometry of the object using an imaging device, and performing a fringe analysis to reconstruct a 3D shape of the object using the fringe patterns and the fringe patterns distorted by the surface geometry of the object. The step of generating the fringe patterns using the dithering technique may include binarizing sinuisoidal fringe patterns with the dithering technique. The step of generating the fringe patterns using the dithering technique may include applying an optimization algorithm.

Abstract: An optical connector system having a first optical connector, a plurality of second optical connectors, and a mounting system hosting the first optical connector and the second optical connectors. The mounting system can be formed integrally with at least one pluggable optical device. The system also has a mechanism arranged to connect the first optical connector to the second optical connectors. The system also includes at least one further pluggable optical device having at least one optical interface optically coupled to the first optical connector of the at least one pluggable optical device. In one example, the pluggable optical device is a CFP device, and the further pluggable optical device is a QSFP+. With this configuration, the QSFP+ can accommodate at least one of a 40 G and 10 G interface capability. Also provided is a connector system and an apparatus (e.g., pluggable optical device) that enable such a capability.

Abstract: In today's reconfigurable optical add/drop multiplexer (ROADM) based optical node, ROADMs multiplex (and demultiplex) colored optical signals to form wavelength-division multiplexed (WDM) signals. Transponders connected to the ROADMs' add/drop ports convert noncolored optical signals to colored optical signals (and vice versa). Dedicating transponders to given ports degrades the node's ability to route around network failures. Example embodiments of the invention include an optical node and corresponding method for routing optical signals within an optical node that compensate for this inflexibility. The optical node may include two ROADMs to transmit respective WDM signals onto at least two internode network paths and a routing module that can direct channels of the same wavelength along different internode network paths.

Abstract: Techniques for providing advertisements in association with electronic content are provided. The advertisements may be provided with electronic content that satisfies a content request made by a particular individual. The advertisements provided in association with the electronic content may depend on the results of an auction between advertisers submitting bids to have their respective advertisements provided in association with the electronic content. The bids may be submitted with respect to different value groups. Each value group includes individuals that may provide an estimated amount of value to a respective advertiser as a customer.

Abstract: Social networks have become platforms to disseminate and market information and ideas. A social network, users, and interactions of users may be modeled by graphs, which may be analyzed to determine influential users. In one example, nodes within a graph may be concurrently grouped into node groupings. Influence values corresponding to node counts within node groupings may be assigned to nodes within node groupings. Influential nodes may be determined based upon the assigned influence values. In another example, degrees of nodes (e.g., an edge count of a node) may be used to determine influential nodes within the graph. Upon selecting a node, degrees of neighboring nodes of the selecting node may be discounted because the node was selected. In another example, trees corresponding to a current node and (e.g., maximum) influential paths from other nodes to the current node may be constructed and evaluated to determine a group of nodes.

Abstract: In today's reconfigurable optical add/drop multiplexer (ROADM) based optical node, ROADMs multiplex (and demultiplex) colored optical signals to form wavelength-division multiplexed (WDM) signals. Transponders connected to the ROADMs' add/drop ports convert noncolored optical signals to colored optical signals (and vice versa). Dedicating transponders to given ports degrades the node's ability to route around network failures. Example embodiments of the invention include an optical node and corresponding method for routing optical signals within an optical node that compensate for this inflexibility. The optical node may include two ROADMs to transmit respective WDM signals onto at least two internode network paths and a routing module that can direct channels of the same wavelength along different internode network paths.

Abstract: The present invention relates to porous polyelectrolyte materials, particularly nanoporous polyelectrolyte materials and to methods of making such materials. In a preferred embodiment, the invention relates to nanoporous polyelectrolyte spheres. In a preferred form of the invention, the materials are manufactured with the use of mesoporous silica spheres as templates. The invention also relates to a method of manufacturing such materials, and in particular, to a method of manufacturing such materials by a layer-by-layer process.

Abstract: A hinged electronic device (100) includes housing hinge mechanism (130) holding together a first housing section (110) with a first screen portion (160) of a hinged screen (150) and a second housing section (120) with a recess (184) for a second screen portion (170) of the hinged screen (150). The first screen portion (160) and the second screen portion (170) are held together by a screen hinge mechanism (480). When the hinged electronic device (100) is closed, the hinged screen (150) is in a stowed position. When the hinged electronic device (100) is fully opened, the hinged screen (150) is in a fully deployed position, which has the first screen portion (160) and the second screen portion (170) within a single plane.

Abstract: A method for testing a test component connected to a high-speed electrical component includes connecting a golden optical component to a high-frequency probe, connecting the high-frequency probe to the high-speed electrical component, operating the test component in an application environment to cause a transmission of a high-speed electrical signal from the high-speed electrical component to the golden optical component, and determining if the golden optical component responds to the high-speed electrical signal.