Patents by Inventor Yan Guo

Yan Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED DIAZEPINE SULFONAMIDES AS BOMBESIN RECEPTOR SUBTYPE-1 MODULATORS
    Publication number: 20100317645
    Abstract: Certain novel substituted diazepine sulfonamides are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.
    Type: Application
    Filed: December 7, 2007
    Publication date: December 16, 2010
    Inventors: Robert K. Baker, Linda L. Chang, Marc Chioda, Harry R. Chobanian, Ying-Duo Gao, Yan Guo, Linus S. Lin, Ping Liu, Ravi P. Nargund, Kathleen M. Rupprecht, Shouwu Miao
  • Dynamic Schema Creation
    Publication number: 20100083092
    Abstract: In a database application executing on a computer system, a database table view is represented by a structured object located on a storage device coupled to the computer system. Responsive to a user pasting content (e.g., spreadsheet data) onto the view of the table, the database application determines if the content to be pasted extends beyond the number of rows (records in a database) or columns (database fields) currently displayed in the table view. If the content extends beyond the number of rows or columns currently displayed, the database application automatically adds one or more records or fields to the structured object on the storage device, and updates the table view to display one or more rows or columns corresponding to the records or fields added to the structured object.
    Type: Application
    Filed: September 30, 2008
    Publication date: April 1, 2010
    Applicant: APPLE INC.
    Inventors: Geoff Schuller, Yan Guo
  • Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
    Patent number: 7560552
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: July 14, 2009
    Assignee: Abbott Laboratories
    Inventors: Michael R. Michaelides, Lee D. Arnold, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji, Neil Wishart
  • Multi-Stage RF Amplifier Including MMICs and Discrete Transistor Amplifiers in a Single Package
    Publication number: 20090039966
    Abstract: A MMIC amplifier stage and a discrete transistor amplifier stage are housed in a single package. In one aspect, a multi-stage RF amplifier includes a package with an RF input lead and an RF output lead. The signal path from the RF input lead to the RF output lead includes one or more MMIC amplifier stages followed by one or more discrete transistor amplifier stages. Each MMIC amplifier stage includes a MMIC with at least one amplifier, and each discrete transistor amplifier stage includes at least one discrete transistor amplifier. All of the MMIC amplifier stages and discrete transistor amplifier stages are housed in the same package.
    Type: Application
    Filed: August 7, 2007
    Publication date: February 12, 2009
    Inventors: Tao Chow, Yan Guo, Eric G. Casida
  • Aperture matched polyrod antenna
    Publication number: 20080252541
    Abstract: A dielectric polyrod having at least one tapered section, where a section exposed outside of the waveguide is tapered a long a curve that depends on the dielectric constant of the material used. The invention also relates to an aperture matched polyrod antenna which includes the same and an inductive tuning element used to achieve wideband impedance match and to create a Gaussian beam in the radiating near field of the antenna, suitable to mimic a small region plane wave.
    Type: Application
    Filed: December 21, 2007
    Publication date: October 16, 2008
    Inventors: Rodolfo Diaz, Jeffrey Peebles, Yan Guo
  • Transgenic evaluation of activated mutant alleles of SOS2 reveals a critical requirement for its kinase activity and C-terminal regulatory domain for salt tolerance in
    Patent number: 7265266
    Abstract: The present invention provides a method of increasing salt tolerance in a plant by overexpressing a gene encoding a mutant SOS2 protein in at least one cell type in the plant. The present invention also provides for transgenic plants expressing the mutant SOS2 proteins.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: September 4, 2007
    Assignees: Arizona Board of Regents/Behalf of University of Arizona, Consejo Superior de Investigaciones Cientificas
    Inventors: Jian-Kang Zhu, Francisco Javier Quintero-Toscano, Jose Manuel Pardo-Prieto, Quansheng Qiu, Karen Sue Schumaker, Masaru Ohta, Changqing Zhang, Yan Guo
  • Thiopyrimidine and isothiazolopyrimidine Kinase Inhibitors
    Publication number: 20060276490
    Abstract: Compounds having the formula are useful for inhibiting protein tyrosine kinases. The present invention also discloses methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.
    Type: Application
    Filed: August 16, 2006
    Publication date: December 7, 2006
    Inventors: Michael Michaelides, Lee Arnold, Michael Curtin, Yujia Dai, Steven Davidsen, Robin Frey, Yan Guo, Zhiqin Ji, Neil Wishart
  • Transgenic evaluation of activated mutant alleles of SOS2 reveals a critical requirement for its kinase activity and C-terminal regulatory domain for salt tolerance in arabidoposis thaliana
    Publication number: 20060168698
    Abstract: The present invention provides a method of increasing salt tolerance in a plant by overexpressing a gene encoding a mutant SOS2 protein in at least one cell type in the plant. The present invention also provides for transgenic plants expressing the mutant SOS2 proteins.
    Type: Application
    Filed: January 24, 2005
    Publication date: July 27, 2006
    Applicants: Arizona Bd of Regents/Behalf of Univ. of Arizona, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
    Inventors: Jian-Kang Zhu, Francisco Quintero-Toscano, Jose Pardo-Prieto, Quansheng Qiu, Karen Shumaker, Masaru Ohta, Changqing Zhang, Yan Guo
  • Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
    Publication number: 20040014756
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 20, 2003
    Publication date: January 22, 2004
    Inventors: Michael R. Michaelides, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji
  • Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
    Publication number: 20030225273
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 3, 2003
    Publication date: December 4, 2003
    Inventors: Michael R. Michaelides, Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji
  • Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
    Publication number: 20030181468
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: March 21, 2002
    Publication date: September 25, 2003
    Inventors: Michael R. Michaelides, Yujia Dai, Steven K. Davidsen, Robin R. Frey, Yan Guo, Zhiqin Ji, Lee D. Arnold, Neil Wishart
  • Inhibitors of histone deacetylase
    Publication number: 20020177594
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: October 26, 2001
    Publication date: November 28, 2002
    Inventors: Michael L. Curtin, Yujia Dai, Steven K Davidsen, Robin R. Frey, Yan Guo, Howard R. Heyman, James H. Holms, Zhiqin Ji, Michael R. Michaelides, Anil Vasudevan, Carol K. Wada
  • 3-substituted indole antiproliferative angiogenesis inhibitors
    Publication number: 20020091148
    Abstract: 3-Substituted indole carbohydrazides having the formula 1
    Type: Application
    Filed: September 14, 2001
    Publication date: July 11, 2002
    Inventors: Nwe Y. BaMaung, Richard A. Craig, Megumi Kawai, Jieyi Wang, Yujia Dai, Yan Guo, George Sheppard, Mary K. Verzal, Anil Vasudevan, Michael Michaelides
  • Reverse hydroxamate inhibitors of matrix metalloproteinases
    Publication number: 20020007060
    Abstract: Compounds having the formula 1
    Type: Application
    Filed: July 16, 2001
    Publication date: January 17, 2002
    Inventors: Steven K. Davidsen, Michael L. Curtin, Joseph F. Dellaria, Alan S. Florjancic, Jamie Giesler-Stacy, Jianchung Gong, Yan Guo, H. Robin Heyman, James H. Holms, Michael R. Michaelides, Douglas Steinman, Carol K. Wada, Lianhong Xu
  • Reverse hydroxamate inhibitors of matrix metalloproteinases
    Patent number: 6294573
    Abstract: Compounds having the formula are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
    Type: Grant
    Filed: January 27, 2000
    Date of Patent: September 25, 2001
    Assignee: Abbott Laboratories
    Inventors: Michael L. Curtin, Yujia Dai, Steven K. Davidsen, Joseph F. Dellaria, Jr., Alan S. Florjancic, Jianchun Gong, Yan Guo, Howard R. Heyman, James H. Holms, Michael R. Michaelides, Jamie R. Stacey, Douglas H. Steinman, Carol K. Wada, Lianhong Xu
  • Inhibitors of matrix metalloproteinases
    Patent number: 6288261
    Abstract: Compounds having the formula and pharmaceutically acceptable salts and prodrugs thereof are matrix metalloproteinase inhibitors. Also disclosed are matrix metalloproteinase-inhibiting compositions and methods of inhibiting matrix metalloproteinase in a mammal.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: September 11, 2001
    Assignee: Abbott Laboratories
    Inventors: David J. Augeri, David A. Betebenner, Richard Craig, Steven K. Davidsen, Stephen W. Fesik, Jamie R. Giesler-Stacey, Yan Guo, Philip J. Hajduk, Michael R. Michaelides, David G. Nettesheim
  • C-terminal ketone inhibitors of matrix metalloproteinases and TNF.alpha. secretion
    Patent number: 5985911
    Abstract: C-terminal compounds of formula ##STR1## are potent inhibitors of matrix metalloproteinase and are useful in the treatment of diseases in which matrix metalloproteinase play a role. Also disclosed are matrix metalloproteinase inhibiting compositions and a method of inhibiting matrix metalloproteinase in a mammal.
    Type: Grant
    Filed: December 17, 1997
    Date of Patent: November 16, 1999
    Assignee: Abbott Laboratories
    Inventors: Steven K. Davidsen, Alan S. Florjancic, George S. Sheppard, Jamie R. Giesler, Lianhong Xu, Yan Guo, Michael L. Curtin, Michael R. Michaelides, Carol K. Wada, James H. Holms
  • Macrocyclic inhibitors of matrix metalloproteinases and TNF.alpha. secretion
    Patent number: 5952320
    Abstract: Macrocyclic compounds of formula ##STR1## are potent inhibitors of matrix metalloproteinase and are useful in the treatment of diseases in which matrix metalloproteinase play a role. Also disclosed are matrix metalloproteinase inhibiting compositions and a method of inhibiting matrix metalloproteinase in a mammal.
    Type: Grant
    Filed: December 17, 1997
    Date of Patent: September 14, 1999
    Assignee: Abbott Laboratories
    Inventors: Steven K. Davidsen, Douglas H. Steinman, George S. Sheppard, Lianhong Xu, James H. Holms, Yan Guo, James B. Summers, Alan S. Florjancic, Michael R. Michaelides
  • Method and apparatus for linear transmission by direct inverse modeling
    Patent number: 5923712
    Abstract: A system for linearly transmitting an amplified output signal using predistortion whereby a straight inverse modeling scheme is used to more easily and accurately determine the inverse of the distortion caused by a power amplifier of a RF transmitter. The "inverse" of the power amplifier is directly modeled by considering the power amplifier as a signal processing block with the input and output ports reversed. As a result, the computationally intensive inversion required by conventional schemes is avoided. The predistorter system stores complex coefficients in a predistorter LUT, which are then used as the tap weights of a digital filter implementing the predistorter. The predistortion is done by a non-linear filter which incorporates both instantaneous and average envelope power or magnitude effects. The predistortion LUT is addressed as a function of the instantaneous envelope power or magnitude and past power or magnitude envelopes.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: July 13, 1999
    Assignee: Glenayre Electronics, Inc.
    Inventors: Robert Richard Leyendecker, Jay Jui-Chieh Chen, Armando Cova Garrido, Yan Guo, Vladimir Pavlovic, Claudio Gustavo Rey, Desmond Wai Ming Yan
  • Compositions useful as a cannabinoid receptor probe
    Patent number: 5872148
    Abstract: A composition of matter, comprising a cannabinol compound having the structure ##STR1## wherein, Q is --C(R.sup.1)(Y.sup.1)--(CH.sub.2).sub.n --Z.sup.1 ; R.sup.1 is --H or --CH.sub.3 ;Y.sup.1 is --CH.sub.3 or Y.sup.2 ; Y.sup.2 is --N.sub.3 or --NCS; n is 4 or 6;Z.sup.1 is --H, when Y.sup.1 is Y.sup.2, or is Z.sup.2, when Y.sup.1 is --CH.sub.3 ; andZ.sup.2 is --N.sub.3 or --NCS.This composition has good binding affinity to the cannabinoid receptor and therefore, is useful as a receptor probe.
    Type: Grant
    Filed: August 8, 1995
    Date of Patent: February 16, 1999
    Assignee: University of Connecticut
    Inventors: Alexandros Makriyannis, Yan Guo, Vasiliki Abadji