Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Abstract: The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

Abstract: A clutch driving mechanism, comprising a motor, a worm, a torsion spring and a clutch rotating arm, wherein the motor is rotationally coupled with the worm, wherein the worm is operably coupled to at least a portion of the torsion spring, and the torsion spring is operably coupled to at least a portion of the clutch rotation arm.

Abstract: The present invention relates to bicyclic himbacine derivatives of the formula or a pharmaceutically acceptable salt thereof, wherein: X is —O—, —N(R), —C(R8)(R9) or —C(O)—; and Y is —O—, —N(R), —C(R8)(R9) or —C(O)— and the remaining variables are described herein. The compounds of the invention are effective inhibitors of the PAR-1 receptor. The inventive compounds may be used for the treatment or prophylaxis of disease states such as ACS, secondary prevention of myocardial infarction or stroke, or PAD.

Abstract: An electronic device with a storable keyboard includes an electronic device, a casing enclosing the electronic device, and a keyboard. The keyboard is couplable to the electronic device to provide electronic input to the electronic device. The casing includes a defined space for storing the keyboard.

Abstract: Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

Abstract: This invention relates to a cardanol modified epoxy resin composition, especially, relates to a cardanol and/or dihydric phenol modified epoxy resin composition, a process making thereof and its application in a low VOC high solids coating, and a low VOC waterborne coating.

Abstract: This invention relates to compounds of Formula I-VI having the following general structure: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure.

Abstract: A multimedia redirection method, a multimedia server, and a computer system. The method includes: receiving a virtual-desktop login request of a user, where the virtual-desktop login request includes an identifier of the user; acquiring, according to the identifier of the user, metadata of a multimedia instance that is not shut down by the user before a last disconnection, where the metadata includes path information of a multimedia file corresponding to the multimedia instance; and sending the metadata to a client of the user so that the client acquires, according to the metadata, multimedia data corresponding to the metadata and plays the multimedia data. The adoption of technical solutions of the present invention can implement that multimedia that is not closed before a last disconnection may be automatically played when a user logs in again, thereby improving experience of multimedia application of the user.

Abstract: The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.

Abstract: A low dropout linear regulator, a starting method, an electronic device, and a chip are provided. The starting method includes the steps of beginning a soft-starting process of the low dropout linear regulator and providing a first current; when an output voltage of the low dropout linear regulator reaches a starting voltage, providing a second current; and dynamically adjusting a threshold of an over current during the soft-starting process of the low dropout linear regulator, wherein the over current includes at least one of the first current and the second current. Through the low dropout linear regulator, the starting method, the electronic device, and the chip, there is short starting time and less overshoot of the output voltage, thereby achieving a fast and safe starting process. Moreover, the circuit is protected, and the usage quality and life is enhanced.

Abstract: The present invention relates to bicyclic himbacine derivatives of the formula or a pharmaceutically acceptable salt thereof, wherein: X is —O—, —N(R), —C(R8)(R9) or —C(O)—; and Y is —O—, —N(R), —C(R8)(R9) or —C(O)— and the remaining variables are described herein. The compounds of the invention are effective inhibitors of the PAR-1 receptor. The inventive compounds may be used for the treatment or prophylaxis of disease states such as ACS, secondary prevention of myocardial infarction or stroke, or PAD.

Abstract: A lock system, comprising a stationary member, a hand operated member, and a coupling member, wherein the stationary member and the hand operated member are configured to be operably coupled by the coupling member, and wherein the connection member is configured to remain within the stationary member and to extend into or retract from the hand operated member.

Abstract: This invention relates to compounds of Formula I-VI having the following general structure: Z1—Y1—(CH2)n1—R—(CH2)n2—Y2—Z2 wherein R is a 6-8 membered saturated heterocyclic ring having 2 Nitrogen atoms connected with —(CH2)n1— and —(CH2)n2—, respectively, and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure.

Abstract: A freestanding ultrasonic probe or transducer position relative to the inspected object is remotely tracked with a wireless transmitter/receiver or an optically based positioning system. Either type of positioning system generates a time stamped or commonly clocked positional data set that are sent to a post data processing module. The post data processing module creates a 3-D model of the inspected object, including location and size of indications in the inspected object, utilizing the positional data and inspection data generated by an ultrasonic testing instrument coupled to the freestanding probe/transducer.

Abstract: A method for probabilistic fatigue life prediction using nondestructive testing data considering uncertainties from nondestructive examination (NDE) data and fatigue model parameters. The method utilizes uncertainty quantification models for detection, sizing, fatigue model parameters and inputs. A probability of detection model is developed based on a log-linear model coupling an actual flaw size with a nondestructive examination (NDE) reported size. A distribution of the actual flaw size is derived for both NDE data without flaw indications and NDE data with flaw indications by using probabilistic modeling and Bayes theorem. A turbine rotor example with real world NDE inspection data is presented to demonstrate the overall methodology.

Abstract: The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.

Abstract: A resource scheduling method and apparatus. The method includes: determining at least one candidate destination physical machine and a physical machine on which a to-be-scheduled virtual machine is located; calculating a candidate communication cost required after the to-be-scheduled virtual machine is scheduled in a simulative way to each candidate destination physical machine; determining a destination physical machine among the at least one candidate destination physical machine according to the communication cost; and scheduling the to-be-scheduled virtual machine to the destination physical machine. In the solutions provided in the embodiments of the present invention, a destination physical machine is determined by calculating a candidate communication cost required after the to-be-scheduled virtual machine is scheduled in a simulative way to each candidate destination physical machine, and then resource scheduling is performed.

Abstract: The present invention is directed to certain oxazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzheimer Disease, and Parkinson's Disease.

Abstract: Embodiments of apparatuses, systems and methods relating to a mixer having high second- and third-order intercept points are disclosed. Other embodiments may be described and claimed.