Abstract: Provided is a reaction cup, comprising cup walls and a cup bottom. The cup walls are provided with clamping portions, the clamping portions can allow a membrane strip to stand upright in the reaction cup, and the connecting area of the two opposite clamping portions forms an upright placement position for the membrane strip. The present invention further provides a molecular hybridization instrument used with the reaction cup, and an analyte testing method. The reaction cup can allow the membrane strip to stand upright therein, and can be opened for operation, thereby reducing the area occupied by the reaction cup on the molecular hybridization instrument, and reducing the area of the molecular hybridization instrument. A plurality of reaction cups can be placed on the molecular hybridization instrument at the same time, which increases the number of tests and improves the utilization and working efficiency of the molecular hybridization instrument.

Abstract: A sound-generating device, a display device, a sound-generating controlling method, and a sound-generating controlling device are provided. The sound-generating device includes: a reflection plate which includes a first sound wave reflection face arranged towards a first direction; a plurality of main loudspeakers, the plurality of main loudspeakers are distributed in an array in a preset three-dimensional space, and the preset three-dimensional space is located at one side of the first sound wave reflection face towards a first direction; the plurality of main loudspeakers include first main loudspeakers with a sound-generating direction towards the first direction, and second main loudspeakers with a sound-generating direction towards a second direction, the second direction is an opposite direction of the first direction; and the sound waves emitted by the second main loudspeakers are transmitted to the first sound wave reflection face and can be reflected by the first sound wave reflection face.

Abstract: Provided herein are antibodies, masked antibodies (e.g., activatable antibodies), and antigen-binding fragments that target human CD47, polynucleotides encoding the same, therapeutic compositions thereof, and their use to treat CD47-positive diseases such as cancer. The masked antibodies described herein may comprise an IgG1 Fc region.

Abstract: A display substrate and a manufacturing method thereof, and a display device are provided. The display substrate includes: a base substrate, a plurality of sub-pixels, a pixel defining layer, and a planarization layer. The pixel defining layer includes a main body portion, the main body portion includes a first main body sub-portion and a second main body sub-portion, the second main body sub-portion protrudes relative to the first main body sub-portion to form a separation structure, at least one of the plurality of film layers is broken at the separation structure, an orthographic projection of a part of the light-emitting functional layer in the opening on the base substrate at least partially overlaps with an orthographic projection of a part of the light-emitting functional layer located on a side of the main body portion away from the base substrate on the base substrate.

Abstract: A display method comprises: acquiring multiple frames of images to be displayed, one frame of two adjacent frames of the images to be displayed being an image in an odd-numbered row, the other frame being an image in an even-numbered row, the resolution of the image in the odd-numbered row being M*(a*N), the resolution of the image in the even-numbered row being M*(a*N) or (M?1)*(a*N), and a being 1 or 2; and causing an odd-numbered display group to display the image in the odd-numbered row, and causing an even-numbered display group to display the image in the even-numbered row, the odd-numbered display group comprising M*(a*N) odd-numbered display units, the even-numbered display group comprising (M?1)*(a*N) even-numbered display units, the odd-numbered display unit in the i-th row comprising a first sub-pixel, a second sub-pixel, and a third sub-pixel in a pixel unit in the i-th row.

Abstract: Methods, systems, and computer-readable storage media for receiving, through a set of user interfaces (UIs), user input including job configuration information and deployment information for an application, providing a CI/CD job for the application with a CI/CD service using the job configuration information and the deployment information, and triggering, in response to a commit of changes to the application in a repository, automated build of the application, and in response, automatically: generating a development descriptor file at least partially based on the user input, providing an archive file including the development descriptor file, and processing, by the CI/CD job executed by the CI/CD service, the archive file to deploy the application within the target environment.

Abstract: An electromagnetic actuator comprises a housing, front and rear magnetic poles, and a guide sleeve. The front magnetic pole is fixed to the housing, the housing has a cavity, the cavity has a closed end and an open end, the open end is closed by the front magnetic pole, and the rear magnetic pole and the guide sleeve are mounted in the cavity; the guide sleeve has a first end facing the open end, a second end facing the closed end, an elastically deformable flange at the first end, and a radially stepped surface at an axially middle portion facing the closed end; the rear magnetic pole is axially abutted between the radially stepped surface and the closed end; and the flange is elastically abutted against the front magnetic pole, such that the guide sleeve and the rear magnetic pole are axially positioned with respect to the housing.

Abstract: A method for computing an estimated data availability for UCI (Uplink Control Information) in an LTE or 5G system enables a base station (e.g., eNodeB or gNodeB) to estimate how much data is available within its allocated PUSCH (Physical Uplink Shared Channel) data for the UCI data. The method enables a UE to insert a sufficient amount of UCI data without consuming resources required for the PUSCH data, thereby preventing decode failures.

Abstract: The present invention relates to the field of new materials technology, in particular to carbon nitride composite ceramic tool materials, preparation method and cutting tools thereof. The raw materials comprise carbon nitride, titanium carbonitride, molybdenum, nickel and cobalt, carbon nitride as the matrix phase, titanium carbonitride as the reinforcing phase are added to the carbon nitride based composite ceramic materials, with molybdenum, nickel and cobalt as a suitable sintering aid, dense composite tool material is obtained with vacuum hot press sintering method. The prepared carbon nitride based composite ceramic tool materials boast the advantages of low cost, high hardness, high bending strength and high fracture toughness, which is an important way to promote the innovation, development and popularization of carbon nitride materials.

Abstract: Provided herein is a heavy chain constant region comprising a CH1 domain, a hinge region, a CH2 domain and a CH3 domain, wherein the sequences of said CH1 domain and hinge region derive from the sequences of CH1 domain and hinge region in human IgG2, the sequences of said CH2 domain and CH3 domain derive from the sequences of CH2 domain and CH3 domain in human IgGs; and wherein, said antibody heavy chain constant region has an affinity to human Fc?RIIB equal to or higher than the affinity of human IgG1 to human Fc?RIIB, said antibody heavy chain constant region has an I/A ratio equal to or higher than human IgG1 has. Also provided are antibodies or fusion proteins based on a heavy chain constant region according to the above, wherein the antibody heavy chain constant region significantly enhances agonistic activity of the antibodies or fusion proteins and improves efficacy of the antibodies or fusion proteins in treating diseases like tumors and autoimmune diseases.

Abstract: Disclosed is a compound of formula (I), and a stereoisomer, a pharmaceutically acceptable salt, a solvate, a co-crystal or a deuterated product thereof, or a pharmaceutical composition containing same, and the use thereof as a CD73 antagonist in the preparation of a drug for treating related diseases, wherein the definition of each group in formula (I) is consistent with the definition in the description.

Abstract: A method for quickly determining the rotor position of a permanent magnet motor using the N-division approach is provided. The method involves converting the motor's three-phase stator current coordinates into the dq two-phase synchronous rotation coordinate system and identifying the initial rotor position area. By establishing a stator current cost model and utilizing the d-axis stator current, the initial rotor position can be obtained. Subsequently, the N-division approach is employed for iterative optimization to obtain the estimated rotor position and the final position region, leading to a rapid estimation of the permanent magnet motor's rotor position. This method incorporates the finite set model predictive control concept into a phase-locked loop based on stator current, eliminating the need for additional rotor position polarity judgment and invalid rotor position control variables.

Abstract: A display device, a sound producing control method, a method and device for determining parameters. The display device includes a plurality of exciters arranged on the display panel, the display panel producing sound on a screen through the plurality of exciters; wherein, the plurality of the exciters are formed as at least one sound producing unit, each sound producing unit includes at least two exciters, and each exciter in the same sound producing unit is connected to a same audio signal input end, in one sound producing unit, a signal filter is provided on an audio transmission line from the audio signal input end to at least one exciter, and used for low frequency compensation of a sound produced by the entire sound producing unit.

Abstract: A method, a device, and a computer-readable storage medium for managing processes are disclosed. The method includes (i) determining a trigger frequency at which a process is activated due to receipt of data within a preset duration, (ii) adjusting a current trust value corresponding to the process based on the trigger frequency, wherein the current trust value is used to indicate the degree of trustworthiness when the process is currently in the normal state, and (iii) managing the state of the process based on the adjusted result of the trust value.

Abstract: A compound of formula (I) and a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, or a pharmaceutical composition containing same, and the use thereof as an AAK1 inhibitor in the preparation of a drug for treating related diseases.

Abstract: A metro rail corrugation measurement method based the Seq2Seq model and vibration and noise data fusion comprises the following steps: Constructing a time series data set corresponding to floor longitudinal acceleration and train speed based on historical data of metro trains; Constructing the metro train mileage matching prediction model based on the Seq2Seq model, training the metro train mileage matching prediction model by time series data sets, and inputting the inside floor longitudinal acceleration of the metro train to be detected into the trained metro train mileage matching prediction model to obtain the running speed of the metro train to be detected. According to the vibration and noise data of the metro train to be detected, the vibration and noise composite index of the rail corrugation is calculated to determine the wavelength and amplitude information corresponding to the rail corrugation.

Abstract: Provided herein are heterocyclic compounds of Formula (I), pharmaceutical compositions containing such a compound and their therapeutic uses, methods for their preparation, intermediate compounds, pharmaceutical compositions containing such a compound, and their therapeutic uses.

Abstract: An insulated gate bipolar transistor, comprising an anode second conductivity-type region and an anode first conductivity-type region provided on a drift region; the anode first conductivity-type region comprises a first region and a second region, and the anode second conductivity-type region comprises a third region and a fourth region, the dopant concentration of the first region being less than that of the second region, the dopant concentration of the third region being less than that of the fourth region, the third region being provided between the fourth region and a body region, the first region being provided below the fourth region, and the second region being provided below the third region and located between the first region and the body region.

Abstract: Hierarchical network operation and resource control system and method for a mega satellite constellation, belonging to the field of spatial information technology, are provided. The hierarchical network operation and resource control system includes a service layer, a global organization layer, a local coordination layer and a resource layer. The service layer is used as an input to drive operation of whole system. The global organization layer is to realize “operation, measurement and control” integrated control and decision of whole network. The local coordination layer is to realize local management decision and management slice generation. The resource layer is to provide physical resource and physical device and realize resource virtualization.

Abstract: A method for enhancing network coverage based on adaptive generation of resource cell. A traditional cell in a network is taken as an initial state of the network. A correlation matrix in a current network state is generated. Whether |?i,jt??i,jt-1|/?i,jt-1>? is determined. Each access point is divided into a plurality of resource cells. A CU-DU network mapping table is generated. A middlehaul link of each of the plurality of resource cells is constructed according to the CU-DU network mapping table.