Abstract: Disclosed is a compound of formula (I), and a stereoisomer, a pharmaceutically acceptable salt, a solvate, a co-crystal or a deuterated product thereof, or a pharmaceutical composition containing same, and the use thereof as a CD73 antagonist in the preparation of a drug for treating related diseases, wherein the definition of each group in formula (I) is consistent with the definition in the description.

Abstract: A method for quickly determining the rotor position of a permanent magnet motor using the N-division approach is provided. The method involves converting the motor's three-phase stator current coordinates into the dq two-phase synchronous rotation coordinate system and identifying the initial rotor position area. By establishing a stator current cost model and utilizing the d-axis stator current, the initial rotor position can be obtained. Subsequently, the N-division approach is employed for iterative optimization to obtain the estimated rotor position and the final position region, leading to a rapid estimation of the permanent magnet motor's rotor position. This method incorporates the finite set model predictive control concept into a phase-locked loop based on stator current, eliminating the need for additional rotor position polarity judgment and invalid rotor position control variables.

Abstract: A display device, a sound producing control method, a method and device for determining parameters. The display device includes a plurality of exciters arranged on the display panel, the display panel producing sound on a screen through the plurality of exciters; wherein, the plurality of the exciters are formed as at least one sound producing unit, each sound producing unit includes at least two exciters, and each exciter in the same sound producing unit is connected to a same audio signal input end, in one sound producing unit, a signal filter is provided on an audio transmission line from the audio signal input end to at least one exciter, and used for low frequency compensation of a sound produced by the entire sound producing unit.

Abstract: A method, a device, and a computer-readable storage medium for managing processes are disclosed. The method includes (i) determining a trigger frequency at which a process is activated due to receipt of data within a preset duration, (ii) adjusting a current trust value corresponding to the process based on the trigger frequency, wherein the current trust value is used to indicate the degree of trustworthiness when the process is currently in the normal state, and (iii) managing the state of the process based on the adjusted result of the trust value.

Abstract: A metro rail corrugation measurement method based the Seq2Seq model and vibration and noise data fusion comprises the following steps: Constructing a time series data set corresponding to floor longitudinal acceleration and train speed based on historical data of metro trains; Constructing the metro train mileage matching prediction model based on the Seq2Seq model, training the metro train mileage matching prediction model by time series data sets, and inputting the inside floor longitudinal acceleration of the metro train to be detected into the trained metro train mileage matching prediction model to obtain the running speed of the metro train to be detected. According to the vibration and noise data of the metro train to be detected, the vibration and noise composite index of the rail corrugation is calculated to determine the wavelength and amplitude information corresponding to the rail corrugation.

Abstract: A compound of formula (I) and a stereoisomer, deuterated compound, solvate, prodrug, metabolite, pharmaceutically acceptable salt or co-crystal thereof, or a pharmaceutical composition containing same, and the use thereof as an AAK1 inhibitor in the preparation of a drug for treating related diseases.

Abstract: Provided herein are heterocyclic compounds of Formula (I), pharmaceutical compositions containing such a compound and their therapeutic uses, methods for their preparation, intermediate compounds, pharmaceutical compositions containing such a compound, and their therapeutic uses.

Abstract: An insulated gate bipolar transistor, comprising an anode second conductivity-type region and an anode first conductivity-type region provided on a drift region; the anode first conductivity-type region comprises a first region and a second region, and the anode second conductivity-type region comprises a third region and a fourth region, the dopant concentration of the first region being less than that of the second region, the dopant concentration of the third region being less than that of the fourth region, the third region being provided between the fourth region and a body region, the first region being provided below the fourth region, and the second region being provided below the third region and located between the first region and the body region.

Abstract: Hierarchical network operation and resource control system and method for a mega satellite constellation, belonging to the field of spatial information technology, are provided. The hierarchical network operation and resource control system includes a service layer, a global organization layer, a local coordination layer and a resource layer. The service layer is used as an input to drive operation of whole system. The global organization layer is to realize “operation, measurement and control” integrated control and decision of whole network. The local coordination layer is to realize local management decision and management slice generation. The resource layer is to provide physical resource and physical device and realize resource virtualization.

Abstract: A method for enhancing network coverage based on adaptive generation of resource cell. A traditional cell in a network is taken as an initial state of the network. A correlation matrix in a current network state is generated. Whether |?i,jt??i,jt-1|/?i,jt-1>? is determined. Each access point is divided into a plurality of resource cells. A CU-DU network mapping table is generated. A middlehaul link of each of the plurality of resource cells is constructed according to the CU-DU network mapping table.

Abstract: A pixel structure, a driving method thereof, a display panel, and a display apparatus are provided. The pixel structure includes: a plurality of pixel rows and a plurality of pixel columns. Each pixel row includes: sub-pixels of four different colors. The plurality of pixel columns include: a plurality of first pixel columns and a plurality of second pixel columns arranged alternately. Each of the first pixel columns includes: sub-pixels of three of the four different colors. Each of the second pixel columns includes: sub-pixels of another color other than the three of the four different colors.

Abstract: A preparation method of soft carbon comprises heating heavy oil to raw coke under a condition of 480° C.-550° C., heating the raw coke to 850° C.-900° C. at a first heating rate of 3° C./min to 5° C./min and holding the temperature for 4 hours or more to obtain a carbon-containing material, grinding and grading the carbon-containing material to obtain a carbon-containing powder, heating the carbon-containing powder to 1030° C.-1220° C. at a second heating rate of 3° C./min to 10° C./min and holding the temperature for 4 hours or more to obtain a carbon material powder, and adding pitch to the carbon material powder, and then heating it to 1030° C.-1220° C. at a third heating rate of 0.90° C./min to 1.25° C./min and holding the temperature for 5 hours or more to obtain soft carbon.

Abstract: The present disclosure provides a gene editing nanocapsule and a preparation method and use thereof. The gene editing nanocapsule has a core-shell structure, wherein the inner core includes a Cas/sgRNA ribonucleoprotein complex, and the outer shell includes a polymer, the Cas/sgRNA ribonucleoprotein complex has a gene editing function, and the polymer acts as a carrier for the Cas/sgRNA ribonucleoprotein complex and protects it, because the polymer contains tumor microenvironment sensitive molecules, the nanocapsules can be efficiently released in tumor cells. Further, the surface of the outer shell can be modified with a targeting agent, so that the nanocapsule can specifically target tumor cells, which improves the endocytosis efficiency of the nanocapsule. The gene editing nanocapsule has good biocompatibility and biosafety, and is expected to become a safe and efficient gene therapy drug for tumors.

Abstract: Disclosed are a borate MWDC with a low dielectric constant and a preparation method thereof by cold sintering. The method for preparing a borate MWDC with a low dielectric constant by cold sintering, including: subjecting a boron source and a metal source to first mixing to obtain a first mixture; subjecting the first mixture to presintering to obtain a presintered material; subjecting the presintered material and a boron oxide solution to second mixing to obtain a second mixture; and subjecting the second mixture to cold sintering to obtain the borate MWDC with the low dielectric constant.

Abstract: Disclosed is a medium to large-sized cable peeling device, including a main component having a base, a cable support positioned on top of the base and a positioning frame positioned in the middle of the cable support; and a cutting assembly positioned below the positioning frame and in the middle of the cable support, the cutting assembly has an adjustment component positioned below the positioning frame, a cutting blade positioned at the bottom of the adjustment component, a locking component positioned inside the cutting blade and a rotating component positioned below the adjustment component and in the middle of the cable support. The invention achieves adjustment of cable peeling based on the thickness of the cable insulation by setting up a main component and a cutting assembly, which prevents damage to cable core during the cutting process and enables the blade to cut at an angle, thereby improving cutting efficiency.

Abstract: An image processing method based on a dither algorithm and a display device are disclosed. The method includes: obtaining a to-be-displayed image, and determining a first region and a second region of the to-be-displayed image, where the first region and the second region are determined according to a coverage range of a visual field of a user on a display screen; determining a first dither algorithm corresponding to the first region and a second dither algorithm corresponding to the second region, where parameter matrices the first dither algorithm and the second dither algorithm are different; and obtaining a rendered image of the to-be-displayed image by rendering the first region according to the first dither algorithm and rendering the second region according to the second dither algorithm, and displaying the rendered image on the display screen.

Abstract: An inter-layer link design method of multilayer constellations with enhanced service coverage capacity is provided, the method includes: establishing a multilayer satellite network spinning T time slot, and obtaining a coordinate of each satellite in the multilayer satellite network at each time slot under a geocentric coordinate system; establishing an adjacency matrix of each constellation in the multilayer satellite network; establishing a feasible set of inter-layer links between adjacent layers in the multilayer satellite network for each time slot; establishing a globally non-uniform service model according to geographical population distribution, and dividing an earth surface into multiple logical area; obtaining a weight of inter-layer link in the feasible set of inter-layer links at each time slot; establishing an assignment model of inter-layer link according to the weight of inter-layer link; and optimizing an inter-layer link set in the feasible set of inter-layer links to obtain a target inter-la

Abstract: The present disclosure provides a GGNMOS transistor structure, an ESD protection device, and an ESD protection circuit. The GGNMOS transistor structure can increase a capability of the ESD protection device to discharge an ESD current per unit size under the action of a P-N-P-N parasitic thyristor formed by an N-potential well, a P-type heavily doped region, and an N-type heavily doped region; the GGNMOS transistor structure can limit a transient peak current of ESD under the action of an equivalent resistor formed by an N-potential well, so that respective GGNMOS transistors of the ESD protection device can conduct uniformly, improving the reliability of the ESD protection circuit.

Abstract: A display compensating method, display compensating device, and display device are provided, which relates to field of display and addresses the issues of poor screen uniformity, grayscale relationship change of sub-pixel due to ambient temperature change, and display screen brightness affected by ageing offset of threshold voltage corresponding to the sub-pixel. The display compensating method is applied to the display device, including: converting a received grayscale signal into a brightness signal; performing an optical compensation on a display brightness of the display device based on the brightness signal; converting a corresponding brightness signal on which the optical compensation is performed into a voltage signal; compensating for a threshold voltage corresponding to each sub-pixel in the display device based on the voltage signal; and compensating for operating parameters of the display device for the display device at different operating temperatures.

Abstract: The present application provides a large-sized single crystal cutting device and a method of using the same. The device includes a cutting system, a commutation system, and a detection system. The cutting system includes a cutting line, a pay-off axis, a guide wheel, and a take-up axis. The commutation system is disposed between the pay-off axis and the take-up axis to adjust a tension and a line speed of the cutting line. The detection system is configured to detect the tension and the line speed of the cutting line.