Abstract: Hierarchical network operation and resource control system and method for a mega satellite constellation, belonging to the field of spatial information technology, are provided. The hierarchical network operation and resource control system includes a service layer, a global organization layer, a local coordination layer and a resource layer. The service layer is used as an input to drive operation of whole system. The global organization layer is to realize “operation, measurement and control” integrated control and decision of whole network. The local coordination layer is to realize local management decision and management slice generation. The resource layer is to provide physical resource and physical device and realize resource virtualization.

Abstract: Lightweight inter-satellite handover device and method for a mega LEO satellite network are provided. An attribute extraction sub-module extracts attributes of handover users in a user information storage unit. Based on the attributes of the handover users, a cluster sub-module clusters the handover users into user clusters. A decision set generator sub-module generates target satellite sets of the user clusters, determines each target satellite of the target satellite sets of the user clusters of each LEO satellite whether belongs to LEO satellites in a management domain of a handover decision point of managing the LEO satellite based on management domain information in a LEO satellite information storage unit, and if YES, performing inter-satellite handover by a centralized decision unit, otherwise performing inter-satellite handover by a distributed decision unit.

Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: An ultrasonic diagnostic imaging system produces an image of shear wave velocities by transmitting push pulses to generate shear waves. A plurality of tracking lines are transmitted and echoes received by a focusing beamformer adjacent to the location of the push pulses. The tracking lines are sampled in a time-interleaved manner. The echo data acquired along each tracking line is processed to determine the time of peak tissue displacement caused by the shear waves at points along the tracking line, and the times of peaks at adjacent tracking lines compared to compute a local shear wave velocity. The resultant map of shear wave velocity values is color-coded and displayed over an anatomical image of the region of interest.

Abstract: A method for preparing artificial graphite includes (A) preparing heavy oil, and forming coke from the heavy oil through continuous coking reaction such that the coke has a plurality of mesophase domains, wherein a size of the mesophase domains ranges between 1 and 30 ?m by polarizing microscope analysis; and (B) processing the coke formed by step (A) sequentially by pre-burning carbonization treatment, grinding classification, high-temperature carbonization treatment and graphitization treatment to form polycrystalline artificial graphite from the coke. The method for preparing artificial graphite of the present invention and the polycrystalline artificial graphite prepared thereby are applicable to batteries.

Abstract: The present invention provides compounds of Formula (Ia) and (Ib): (Ia) or (Ib), or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I): (I), or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I), or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: Disclosed herein is a series of helical sulfono-?-AApeptides that mimic the binding mode of the ?-helical HD2 domain of B-Cell Lymphoma 9 (BCL9). As disclosed herein, sulfono-?-AApeptides can structurally and functionally mimic the ?-helical domain of BCL9, and selectively disrupt ?-catenin/BCL9 PPIs with even higher potency. More intriguingly, these sulfono-?-AApeptides can enter cancer cells, bind with ?-catenin and disrupt ?-catenin/BCL PPI, and exhibit excellent cellular activity, which is much more potent than the BCL9 peptide. Furthermore, enzymatic stability studies demonstrated the remarkable stability of the helical sulfono-?-AApeptides, with no degradation in the presence of pronase for 24 h, augmenting their biological potential.

Abstract: The present invention provides compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein X1, X2, X3, and X4 are each independently CR6 or N; provided that no more than two of X1, X2, X3, or X4 are N; Q2 is N or NR5a; one of Q1 and Q3 is CR5, and the other is N or NR5a; and the dashed circle denotes optional bonds forming an aromatic ring; Y1 is O or NR3; Y2 is —CO—, —SO2—, or —S(O(NH)—; Y3 is O or NR4a; provided that (1) Y1 and Y3 are not both O, and (2) when Y2 is C(O), Y1 is not O; L is a covalent bond or C1-4 alkylene substituted with 0 to 4 R7; R1 is (—CH2)aR9; a is an integer of 0 or 1; R2 is each independently halo, cyano, hydroxyl, amino, C1-6 alkyl, C3-6 cycloalkyl, C4-6 heterocyclyl, alkylamino, haloalkyi, hydroxyalkyi, aminoalkyi, alkoxy, alkoxyalkyl, haloalkoxyalkyl, or haloalkoxy; n is an integer of 0, 1, or 2; R3 and R4a are independently hydrogen, C1-6 alkyl, haloalkyi, hydroxyalkyi, aminoalkyi, alkoxyalkyl, haloalkoxyalkyl, alkoxy, or

Abstract: The invention relates to an automated driving control system, including: a data exchange unit configured to obtain video data streams and distribute the video data streams to at least one computing unit; the at least one computing unit configured to compute perception result data based on the video data streams; a sensor fusion unit configured to fuse the perception result data and sensor data, to obtain fusion result data; and a planning control unit configured to generate a driving control instruction based on the fusion result data, where the planning control unit or the sensor fusion unit is configured to provide a bypass of the data exchange unit. When anomalies occur in any of the units, the automated driving control system may provide a corresponding bypass to keep an automated driving function going.

Abstract: Introduced here are risk management platforms able to implement an automated framework designed to manage, parse, and analyze data for purposes of facilitating compliance with relevant policies in a distributed computer environment. By implementing the technology described herein, an entity can ensure that it complies with the latest regulatory policies, recognizes emerging risks, and conducts more efficient operational planning. A risk management platform can generate interfaces through which an individual (also referred to as a “user”) can interact with the risk management platform. Through these interfaces, the user can apply programmed models to financial data associated with an entity to predict the performance of the entity under various economic scenarios.

Abstract: The present invention provides compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: A method for preparing artificial graphite includes (A) preparing heavy oil, and forming coke from the heavy oil through continuous coking reaction such that the coke has a plurality of mesophase domains, wherein a size of the mesophase domains ranges between 1 and 30 ?m by polarizing microscope analysis; and (B) processing the coke formed by step (A) sequentially by pre-burning carbonization treatment, grinding classification, high-temperature carbonization treatment and graphitization treatment to form polycrystalline artificial graphite from the coke. The method for preparing artificial graphite of the present invention and the polycrystalline artificial graphite prepared thereby are applicable to batteries.

Abstract: The present invention provides compounds of Formula (Ia) or (Ib): (Ia) or (Ib), or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I): Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: The present invention provides compounds of Formula (I): or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.

Abstract: A method for enhancing network coverage based on adaptive generation of resource cell. A traditional cell in a network is taken as an initial state of the network. A correlation matrix in a current network state is generated. Whether |?i,jt??i,jt-1|/?i,jt-1>? is determined. Each access point is divided into a plurality of resource cells. A CU-DU network mapping table is generated. A middlehaul link of each of the plurality of resource cells is constructed according to the CU-DU network mapping table.