Patents by Inventor Yan Shi

Yan Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170129794
    Abstract: A method of operating a waste water treatment facility to prevent bulking in which growth of floc forming bacteria is promoted within a selector aeration tank by controlling absorption and bio-oxidation of biodegradable soluble chemical oxygen demand by the bacteria. Absorption is controlled through measurement of a percentage removal of biodegradable soluble chemical oxygen demand and bio-oxidation is controlled through measurement of temperature corrected specific oxygen uptake rate. Both the absorption and bio-oxidation levels are controlled by decreasing the degree to which wastewater influent flow bypasses the selector aeration tank in favor of the main aeration tank when either of absorption or bio-oxidation are below targeted ranges and increasing flow rate of recycle activated sludge from the clarifier to the main aeration tank while decreasing recycle activated sludge flow rate to the selector aeration tank when absorption and bio-oxidation are above such targeted ranges.
    Type: Application
    Filed: July 4, 2014
    Publication date: May 11, 2017
    Inventors: Randall B. Marx, Malcolm E. Fabiyi, Yan Shi
  • Publication number: 20170081640
    Abstract: The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing pluripotency.
    Type: Application
    Filed: November 30, 2016
    Publication date: March 23, 2017
    Inventors: Yan Shi, Caroline Desponts, Sheng Ding, Hongyan Zhou, Tongxiang Lin, Wenlin Li, Saiyong Zhu
  • Patent number: 9598390
    Abstract: The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 21, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yan Shi, Hao Zhang, Peter T. W. Cheng, Shiwei Tao
  • Patent number: 9601826
    Abstract: Disclosed are an MIMO antenna, a terminal and a method for improving MIMO antenna isolation. The MIMO antenna comprises at least two single antennas arranged on a printed circuit board (PCB); the single antenna comprising: an antenna support, a feeding grounding branch node used for shielding low-frequency coupling between the single antennas, a feeding point, a grounding point and an antenna radiation part, wherein the antenna support is arranged on the PCB, and the antenna radiation part is arranged on the antenna support; and the feeding grounding branch node is connected with the antenna radiation part via the feeding point and the grounding point.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: March 21, 2017
    Assignee: ZTE CORPORATION
    Inventors: Hao Ai, Yan Shi, Long Li, Lu Zhang, Jun Xing, Hao Sun
  • Patent number: 9540615
    Abstract: The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing pluripotency.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: January 10, 2017
    Assignee: The Scripps Research Institute
    Inventors: Yan Shi, Caroline Desponts, Sheng Ding, Hongyan Zhou, Tongxiang Lin, Wenlin Li, Saiyong Zhu
  • Patent number: 9534205
    Abstract: The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing pluripotency.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: January 3, 2017
    Assignee: The Scripps Research Institute
    Inventors: Yan Shi, Caroline Desponts, Sheng Ding, Hongyan Zhou, Tongxiang Lin, Wenlin Li, Saiyong Zhu
  • Publication number: 20160369244
    Abstract: The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing pluripotency.
    Type: Application
    Filed: June 10, 2016
    Publication date: December 22, 2016
    Inventors: Yan Shi, Caroline Desponts, Tongxiang Lin, Wenlin Li, Saiyong Zhu, Sheng Ding
  • Patent number: 9518000
    Abstract: The present invention provides compounds of Formula (I): (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: December 13, 2016
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yan Shi, Peter T. W. Cheng, Ying Wang, Shung C. Wu, Hao Zhang
  • Publication number: 20160275116
    Abstract: A computer-implemented method for analyzing free and open source software (FOSS) data related to FOSS components in source or binary codebase include receiving, by a computer, FOSS data. Each data record in the FOSS data includes identification of a FOSS component in source or binary codebase and data on one or more attributes of the FOSS component. The computer-implemented method further includes storing the FOSS data in a column-based database and querying the FOSS data stored in the database to extract information to put in a FOSS compliance, quality or security report or bill of materials (BoM) for the source or binary codebase.
    Type: Application
    Filed: March 19, 2015
    Publication date: September 22, 2016
    Inventors: Yan SHI, Navjot SINGH, Zifei SHI, Hamad ZAWAWI, Baljeet Singh MALHOTRA
  • Publication number: 20160254596
    Abstract: Disclosed are an MIMO antenna, a terminal and a method for improving MIMO antenna isolation. The MIMO antenna comprises at least two single antennas arranged on a printed circuit board (PCB); the single antenna comprising: an antenna support, a feeding grounding branch node used for shielding low-frequency coupling between the single antennas, a feeding point, a grounding point and an antenna radiation part, wherein the antenna support is arranged on the PCB, and the antenna radiation part is arranged on the antenna support; and the feeding grounding branch node is connected with the antenna radiation part via the feeding point and the grounding point.
    Type: Application
    Filed: November 26, 2013
    Publication date: September 1, 2016
    Inventors: Hao Ai, Yan Shi, Long Li, Lu Zhang, Jun Xing, Hao Sun
  • Publication number: 20160187740
    Abstract: The present invention relates to a display device having a plurality of sub-pixels wherein at least one of the sub-pixels has at least one reflection area and at least two transmission areas, comprising: a first substrate; a first electrode layer disposed over the first substrate; a second substrate; a second electrode layer disposed over the second substrate; a liquid crystal layer interposed between the first substrate and the second substrate; and a protrusion unit disposed on the second substrate; wherein the protrusion unit is disposed correspondingly to the reflection area, and the reflection area is interposed between the transmission areas.
    Type: Application
    Filed: November 30, 2015
    Publication date: June 30, 2016
    Inventors: Chao-Yin LIN, Yan-Shi CHEN, Chien-Hua LEE
  • Patent number: 9342388
    Abstract: Embodiments of the present invention provide methods, program products, and systems to increase efficiency in message oriented middleware. Embodiments of the present invention can, responsive to receiving from an application an open request for a queue alias of a queue manager, provide to the application target cache information which includes a target name and a change flag count associated with the queue alias. Embodiments of the present invention can, responsive to receiving a message from the application that includes respective target cache information including a target name and a change flag count, determine a target location, wherein if the change flag count of the received message matches a current change flag count of the queue alias, the determined target location is a target location associated with the received target name.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: May 17, 2016
    Assignee: International Business Machines Corporation
    Inventors: Qian Li Jin, Yan Shi, Fan Yang, Shan Yu, Yang Zhang
  • Publication number: 20160039780
    Abstract: The present invention provides compounds of Formula (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 11, 2016
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Yan Shi, Hao Zhang, Peter T.W. Cheng, Shiwei Tao
  • Publication number: 20160016880
    Abstract: The present invention provides compounds of Formula (I): (I) or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR120 G protein-coupled receptor modulators which may be used as medicaments.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 21, 2016
    Inventors: Yan Shi, Peter T.W. Cheng, Ying Wang, Shung C. Wu, Hao Zhang
  • Patent number: 9018018
    Abstract: The invention relates to a method and a device for determining the cell activation of a target cell by an activator, said method having the following steps: provision of a probe measuring device with a probe sample arrangement having a measuring probe and a sample holder; loading of the probe sample arrangement with a target cell and with an activator assigned to the target cell, the measuring probe being loaded with the activator, and the sample holder being loaded with the target cell, or vice versa; relative mutual displacement of the measuring probe and the sample holder until contact is made between the target cell and the activator by means of a displacement apparatus of the probe measuring device; recording of measurement values, indicating binding between the target cell and the activator, for the measuring probe with the probe measuring device during the relative displacement of the measuring probe and the sample holder; and determination of a dimension for the cell activation of the target cell from
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: April 28, 2015
    Assignee: JPK Instruments AG
    Inventors: Matthias Amrein, Yan Shi
  • Publication number: 20140088418
    Abstract: Functional imaging for localization in biological tissue entails measuring a response in the tissue (240) to electromagnetic radiation. A catheter (200) for real-time monitoring of cardiac ablation is employed to distinguish a hemorrhage zone (232) from the sandwiching necrotic and healthy tissue, or to distinguish exogenous photoacoustic contrast agent from bordering native tissue. A pair of wavelengths is selected for differential absorption (244) of the radiation in, correspondingly, the hemorrhage zone or where the contrast agent exists, and relatively similar absorption elsewhere. Near infrared laser or LED light may be used photoacoustically to serially acquire (S310, S320) the two datasets to be compared, each representative of a time waveform. Alternatively, acquisition is for a pair of wavelength bands of microwave-induced thermoacoustic data.
    Type: Application
    Filed: March 27, 2012
    Publication date: March 27, 2014
    Applicant: KONINKLIJKE PHILIPS N.V.
    Inventors: Emil Radulescu, Sheng-Wen Huang, Ramon Erkamp, Ladislav Jankovic, Yan Shi, Khalid Shahzad
  • Patent number: 8614332
    Abstract: Compounds are provided which are phosphonate and phosphinate activators and thus are useful in treating diabetes and related diseases and have the structure is a heteroaryl ring; R4 is —(CH2)n—Z—(CH2)m—PO(OR7)(OR8), —(CH2)nZ—(CH2)m—PO(OR7)R9, —(CH2)n—Z—(CH2)m—OPO(OR7)R9, —(CH2)nZ—(CH2)m—OPO(R9)(R10), or —(CH2)nZ—(CH2)m—PO(R9)(R10); R5 and R6 are independently selected from H, alkyl and halogen; Y is R7(CH2)s or is absent; and X, n, Z, m, R4, R5, R6, R7, and s are as defined herein; or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: December 24, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Denis E. Ryono, Peter T. W. Cheng, Scott A. Bolton, Sean Chen, Yan Shi, Wei Meng, Joseph A. Tino, Richard B. Sulsky
  • Patent number: 8597664
    Abstract: Methods of modulating the immune response using pharmaceutical compositions containing crystalline adjuvants are described. In various embodiments the crystalline adjuvants are selected from the group consisting of monosodium urate (MSU), xanthine, basic calcium phosphate (BCP), calcium pyrophosphate dihydrate (CPPD), hydroxyapatite, calcium oxalate, cholesterol, lipid liquid, other crystalline lipids, lithium heparin, talc, and starch.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: December 3, 2013
    Assignee: University of Massachusetts
    Inventors: Kenneth L. Rock, Yan Shi
  • Publication number: 20130317362
    Abstract: The weighted-average-based position (244) in the temporal domain is computed based on the sampling of shear wave displacement (226) along the propagation path. The weighting is, for example, by displacement observed at times (230) corresponding to sampling and represents the time of arrival of the shear wave at the shear-wave propagation path location being sampled. In some embodiments, the computed shear-wave times of arrival at respective locations are functionally related to known inter-location distances (250) to derive shear-wave group velocity. The derived velocity can serve as input into known algorithms for estimating shear elasticity of the medium, such as body tissue, for purposes of clinical diagnosis and therapy assessment.
    Type: Application
    Filed: December 19, 2011
    Publication date: November 28, 2013
    Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.
    Inventors: Yan Shi, Hua Xie, Roy Peterson, Jean-Luc Robert, Vijay Shamdasani
  • Publication number: 20130273536
    Abstract: The present invention provides for identification and use of small molecules to induce pluripotency in mammalian cells as well as other methods of inducing pluripotency.
    Type: Application
    Filed: March 14, 2013
    Publication date: October 17, 2013
    Inventors: Yan Shi, Caroline Desponts, Sheng Ding, Hongyan Zhou, Tongxiang Lin, Wenlin Li, Saiyong Zhu