Abstract: Described herein are biomimetic Janus particles useful as artificial antigen presenting cells capable of activating T cells in vitro. “Bull's eye” ligand patterns mimicking either the native or reverse organization of the T cell immunological synapse are provided on the surface of nano- or micro-sized particles. Methods for activating T cells in vitro using biomimetic Janus particles described herein are also provided. T cells activated by the biomimetic Janus particles can be used in adoptive immunotherapies for treating cancer, tolerance induction in autoimmune disease, autologous immune enhancement therapy, and viral infection immunotherapy. Also described herein are methods for producing a biomimetic Janus particle.

Abstract: A chassis includes a housing, a partition, a movable member and a tray. The housing includes a top plate and a bottom plate, and the top plate is opposite to the bottom plate. An accommodating space is located between the top plate and the bottom plate. The bottom plate has a through hole. The partition is disposed in the accommodating space. The movable member is connected to the partition. The movable member is configured to move between a first position and a second position. The tray includes a latch member. When the movable member is located at the first position and the tray is placed into the accommodating space, the movable member is embedded into the through hole and the latch member engages with the movable member. When the movable member is located at the second position, the movable member disengages from the through hole.

Abstract: A computer program product has a computer-readable storage medium having computer program instructions embodied therein for performing a method for implementing a privacy policy for a user. The method may include the user developing rules that determine whether another user (requester) can access information related to the user. The rules may be stored in a database coupled to a server and evaluated when a request is received from the requester to access the information. If a rule is satisfied by the requester, the server can return the information to the requester. The information can be returned at a level of granularity specified by the user in the satisfied rule. A privacy level can be set by the user to allow access to requesters based on the rules or to deny access to any requesters.

Abstract: The instant disclosure relates to microemulsion compositions comprising polydatin, which are useful as cosmetic and/or pharmaceutical compositions for application to the skin and/or hair. The microemulsion compositions comprise: (a) polydatin; (b) optionally, niacinamide; (c) optionally, baicalin; (d) one or more oils; (e) water; and (f) one or more emulsifiers. Furthermore, the ratio of the total amount of the one or more emulsifiers to the total amount of the one or more oils is typically 1.7 to 2.5.

Abstract: Lookup-table hardware search engine belongs to the field of information technology, and is used to improve the traditional TCAM hardware search engine to make the circuit performance higher. The technical points are: including SL decoder, TL-TCAM array, the data stored in the TL-TCAM hardware search engine is obtained by performing lookup table operation in the corresponding TCAM hardware search engine, the decoder is used to decode the search word and send it to the TL-TCAM hardware search engine array, the decoding is to convert a search word SL corresponding to data in a TCAM hardware search engine table into a search word LSL corresponding to TL-TCAM hardware search engine table data, the effect is that TCAM adds a decoder, cooperates with the decoder and by lookup table method converts the TCAM table data to a new circuit unit that can be adapted to the added search line.

Abstract: Systems and methods according to aspects of the invention verify requests for information over a network. Computing devices communicating over a network transmit numerous signals with various types of information including spatial information, temporal information, device-specific information, and transmission specific information. This information may be used to generate statistical records of valid request for information. Various combinations of these signals may be used to determine whether a request for information is a valid request based on the statistical records associated with the signals. Where a request for information has been verified, the system and method may provide the information. Where the request for information has not been verified, the system and method may deny the request for information. Thus the system and method may be used to prevent and block scraping and spamming attacks.

Abstract: A system, method, and apparatus are provided for visualizing quotas on resources within a computing environment (e.g., a data center, a computing cluster) that includes multiple brokers, gateway servers, or other entities that control access to the resource(s). Through a visualization interface, an operator of a quota system can set, change, and/or delete quotas on resources and/or sub-resources for any number of clients or consumers of the resources. The visualization interface may also enable access to a log of changes to quotas and/or graphs or other displays of statuses of any selected quotas for any selected clients and resources/sub-resources.

Abstract: In one embodiment, a method includes, by one or more server computing devices, receiving state data of a client computing device. The state data includes event data indicating events generated by or occurring at the client computing device and context data associated with the event data. The context data indicates device states of the client computing device that each coincide with one or more of the events and indicate a context of the one or more of the events. The method also includes, by one or more server computing devices, ordering the events and the device states in the event and context data into a state-data-review structure and analyzing the state-data-review structure to generate one or more recommendations on operation of the client computing device.

Abstract: Provided is a pyridone or pyrimidone derivative(s) represented by general formula (I) and its preparation method and use. Substituents of the compound of general formula (I) are defined the same as in the specification.

Abstract: A wave-dissipating float for a swimming pool lane rope includes a cylindrical body composed of a first casing and a second casing. The cylindrical body is provided with a fixing hole and at least one perforation. For installation, it is not necessary to disassemble one end of the swimming pool lane rope. The rope of the lane rope is placed in a first semicircular fixing hole of the first casing and a second semicircular fixing hole of the second casing, and then the first casing and the second casing are coupled to each other so that the rope of the lane rope is surrounded by the cylindrical body to complete the assembly.

Abstract: A system, method, and apparatus are provided for identifying clients or consumers of one or more controlled resources within a computing environment (e.g., a data center, a computing cluster). The resources may be controlled via the enforcement of quotas, wherein different clients have different quotas for the controlled resource(s). A client associated with a given call to a resource is identified using a tuple formed from identifiers of multiple services in the call stack, such as a first service (e.g., a front-end or user-facing service) and an immediate service (e.g., a final service in the stack prior to receipt of the call at a gateway, broker, or other entity that manages access to the controlled resources).

Abstract: The instant disclosure relates to microemulsion compositions comprising polydatin, which are useful as cosmetic and/or pharmaceutical compositions for application to the skin and/or hair. The microemulsion compositions comprise: (a) polydatin; (b) optionally, niacinamide; (c) optionally, baicalin; (d) one or more oils; (e) water; and (f) one or more emulsifiers. Furthermore, the ratio of the total amount of the one or more emulsifiers to the total amount of the one or more oils is typically 1.7 to 2.5.

Abstract: A method for manufacturing thin strip continuously cast 700 Mpa grade high strength weather-resistant steel, the method comprising the following steps: 1) casting a 1-5 mm thick cast strip in a double roller continuous casting machine, the cast strip comprising the following chemical compositions by weight percent: C 0.03-0.1%, Si?0.4%, Mn 0.75-2.0%, P 0.07-0.22%, S?0.01%, N?0.012%, and Cu 0.25-0.8%, further comprising more than one of Nb, V, Ti and Mo: Nb 0.01-0.1%, V 0.01-0.1%, Ti 0.01-0.1%, and Mo 0.1-0.5%, and the balance being Fe and unavoidable impurities; 2) cooling the cast strip at a rate greater than 20° C./s; 3) hot rolling the cast strip under a temperature of 1050-1250° C. at a reduction rate of 20-50% and a deformation rate greater than 20 s?1; then conducting austenite online recrystallization, the thickness of the hot rolled strip being 0.5-3.0 mm; 4) cooling at a rate of 10-80° C./s; and 5) rolling up under a temperature of 500-650° C.

Abstract: An amplifier device includes an amplifier circuit, a feedback circuit, and a filter circuit. The amplifier circuit is configured to receive an input signal and a filtered signal, and to output a first output signal and a second output signal at a first output terminal and a second output terminal respectively. The first output signal and the second output signal are a pair of differential signals. The feedback circuit is configured to set direct current (DC) voltage levels of the first output signal and the second output signal to be at a predetermined voltage. The filter circuit is configured to low-pass filter the input signal or to low-pass filter the pair of differential signals so as to generate the filtered signal, and is configured to output the filtered signal to the amplifier circuit.

Abstract: Compositions comprising an isolate or extract comprising mangiferin, one or more of ferulic acid, Vitamin C, and baicalin, present in amounts sufficient to produce synergistic antioxidant activity and provided for cosmetic and other uses.

Abstract: An amplifier device includes an amplifier circuit, a feedback circuit, and a filter circuit. The amplifier circuit is configured to receive an input signal and a filtered signal, and to output a first output signal and a second output signal at a first output terminal and a second output terminal respectively. The first output signal and the second output signal are a pair of differential signals. The feedback circuit is configured to set direct current (DC) voltage levels of the first output signal and the second output signal to be at a predetermined voltage. The filter circuit is configured to low-pass filter the input signal or to low-pass filter the pair of differential signals so as to generate the filtered signal, and is configured to output the filtered signal to the amplifier circuit.

Abstract: Systems and methods according to aspects of the invention verify requests for information over a network. Computing devices communicating over a network transmit numerous signals with various types of information including spatial information, temporal information, device-specific information, and transmission specific information. This information may be used to generate statistical records of valid request for information. Various combinations of these signals may be used to determine whether a request for information is a valid request based on the statistical records associated with the signals. Where a request for information has been verified, the system and method may provide the information. Where the request for information has not been verified, the system and method may deny the request for information. Thus the system and method may be used to prevent and block scraping and spamming attacks.

Abstract: A method for continuous thin strip casting comprises: introducing molten steel through a long nozzle into a tundish from a ladle, the tundish is one strand tundish, and the molten steel flows below a weir, then passes a first dam and enters a channel with an induction heating device, and the heated molten steel then flows out from an outlet at the other side of the tundish to a nozzle also with an induction heating device for casting. The distances between the weirs of the tundish and the channel have optimal distance ranges. The present invention can improve the casting stability and the quality of the casting strip.

Abstract: A manufacturing method for strip casting 550 MPa-grade high strength atmospheric corrosion-resistant steel strip, comprising the following steps: 1) smelting, where the chemical composition of a molten steel is that: C is between 0.03-0.08%, Si?0.4%, Mn is between 0.6-1.5%, P is between 0.07-0.22%, S?0.01%, N?0.012%, Cu is between 0.25-0.8%, Cr is between 0.3-0.8%, and Ni is between 0.12-0.4%, additionally, also comprised is at least one micro-alloying element among Nb, V, Ti, and Mo, where Nb is between 0.01-0.08%, V is between 0.01-0.08%, Ti is between 0.01-0.08%, and Mo is between 0.1-0.4%, and where the remainder is Fe and unavoidable impurities; 2) strip casting, where a 1-5 mm-thick cast strip is casted directly; 3) cooling the strip, where the cooling rate is greater than 20° C./s; 4) online hot rolling the cast strip, where the hot rolling temperature is between 1050-1250° C.

Abstract: Described herein are biomimetic Janus particles useful as artificial antigen presenting cells capable of activating T cells in vitro. “Bull's eye” ligand patterns mimicking either the native or reverse organization of the T cell immunological synapse are provided on the surface of nano- or micro-sized particles. Methods for activating T cells in vitro using biomimetic Janus particles described herein are also provided. T cells activated by the biomimetic Janus particles can be used in adoptive immunotherapies for treating cancer, tolerance induction in autoimmune disease, autologous immune enhancement therapy, and viral infection immunotherapy. Also described herein are methods for producing a biomimetic Janus particle.