Patents by Inventor Yanggu Shi

Yanggu Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 98 human secreted proteins
    Publication number: 20060079670
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 20, 2005
    Publication date: April 13, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig Rosen, Steven Ruben, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Ying-Fei Wei, Jian Ni, Kimberly Florence, Paul Young, Laurie Brewer, Daniel Soppet, Gregory Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • 157 human secreted proteins
    Publication number: 20060073561
    Abstract: The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
    Type: Application
    Filed: November 12, 2004
    Publication date: April 6, 2006
    Inventors: Craig Rosen, Steven Ruben, Henrik Olsen, Kevin Baker, Michele Fiscella, Ping Wei, Charles Birse, George Komatsoulis, Gil Choi, Paul Moore, Ram Gupta, Yanggu Shi
  • 33 human secreted proteins
    Publication number: 20060036089
    Abstract: The present invention relates to 33 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 3, 2005
    Publication date: February 16, 2006
    Applicant: Human Genome Sciences, Inc.
    Inventors: Daniel Soppet, Paul Moore, Yanggu Shi, Steven Ruben, Craig Rosen, David LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly Florence, Paul Young, George Komatsoulis, Jian Ni
  • 27 human secreted proteins
    Publication number: 20050239099
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 27, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Jian Ni, Reinhard Ebner, Craig Rosen, Yanggu Shi, Charles Birse, Kimberly Florence, George Komatsoulis, David LaFleur, Paul Moore, Henrik Olsen, Paul Young
  • Antibodies against human protein HUVDJ43
    Patent number: 6953667
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: January 25, 2002
    Date of Patent: October 11, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • 70 human secreted proteins
    Publication number: 20050215775
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: November 2, 2004
    Publication date: September 29, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Craig Rosen, Carrie Fischer, Daniel Soppet, Kenneth Carter, Daniel Bednarik, Gregory Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul Young, John Greene, Ann Ferrie, D. Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Yanggu Shi
  • 86 human secreted proteins
    Publication number: 20050214844
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: April 22, 2005
    Publication date: September 29, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Moore, Yanggu Shi, Craig Rosen, Steven Ruben, David Lafleur, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Paul Young, John Greene, Ann Ferrie, Guo-Liang Yu, Jian Ni, Ping Feng
  • 89 human secreted proteins
    Publication number: 20050208602
    Abstract: The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
    Type: Application
    Filed: February 9, 2004
    Publication date: September 22, 2005
    Inventors: Craig Rosen, Kevin Baker, Charles Birse, Gil Choi, Michele Fiscella, George Komatsoulis, Paul Moore, Jian Ni, Henrik Olsen, Steven Ruben, Ping Wei, D. Roxanne Duan, Yanggu Shi
  • 50 human secreted proteins
    Publication number: 20050208622
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 22, 2004
    Publication date: September 22, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Paul Moore, Steven Ruben, David LaFleur, Yanggu Shi, Craig Rosen, Henrik Olsen, Reinhard Ebner, Laurie Brewer
  • 29 human secreted proteins
    Publication number: 20050208619
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 29, 2004
    Publication date: September 22, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig Rosen, Steven Ruben, Reinhard Ebner, Roxanne Duan, Jian Ni, Daniel Soppet, Paul Moore, Yanggu Shi, David LaFleur, Henrik Olsen, Charles Birse, George Komatsoulis
  • Secreted protein HCE3C63
    Patent number: 6936691
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 30, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • 70 human secreted proteins
    Publication number: 20050181371
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 21, 2003
    Publication date: August 18, 2005
    Inventors: Craig Rosen, George Komatsoulis, Kevin Baker, Michele Fiscella, Paul Moore, Ping Wei, D. Duan, Yanggu Shi, Ram Gupta
  • Interleukin 17 receptor-like protein
    Publication number: 20050181372
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating, diagnosing, detecting, and/or preventing immune system-related disorders.
    Type: Application
    Filed: August 22, 2003
    Publication date: August 18, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven Ruben
  • 44 human secreted proteins
    Publication number: 20050153335
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 3, 2004
    Publication date: July 14, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • 70 human secreted proteins
    Publication number: 20050095612
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: June 15, 2004
    Publication date: May 5, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Paul Young, Laurie Brewer, Reinhard Ebner, Henrik Olsen, Kimberly Florence, Craig Rosen, Roxanne Duan, Paul Moore, Yanggu Shi, David LaFleur, Charles Florence, Daniel Soppet, Gregory Endress, Ping Feng, George Komatsoulis
  • 87 human secreted proteins
    Publication number: 20050089911
    Abstract: The present invention relates to 87 novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 8, 2004
    Publication date: April 28, 2005
    Inventors: Paul Young, John Greene, Ann Ferrie, Steven Ruben, Craig Rosen, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik Olsen, Reinhard Ebner, Laurie Brewer, Paul Moore, Yanggu Shi, David LaFleur, Jian Ni
  • 44 human secreted proteins
    Publication number: 20050079537
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 3, 2004
    Publication date: April 14, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • Protein HMAAD57
    Patent number: 6878687
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: April 12, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, George Komatsoulis, Yanggu Shi
  • 101 human secreted proteins
    Publication number: 20050069943
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: November 3, 2004
    Publication date: March 31, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Roxanne Duan, Steven Ruben, Kimberly Florence, John Greene, Craig Rosen, Paul Young, Ann Ferrie, Guo-Liang Yu, Fouad Janat, Jian Ni, Kenneth Carter, Gregory Endress, Ping Feng, David LaFleur, Yanggu Shi
  • 83 human secreted proteins
    Publication number: 20050037467
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 9, 2004
    Publication date: February 17, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Ping Feng, David LaFleur, Paul Moore, Yanggu Shi, Hla Kyaw, Yi Li, ZhiZhen Zeng, Kenneth Carter, Gregory Endress, Ying-Fei Wei, Ping Fan, Craig Rosen