Patents by Inventor Yanggu Shi

Yanggu Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

50 human secreted proteins

Publication number: 20030166906

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: April 11, 2003

Publication date: September 4, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Paul A. Moore, Steven M. Ruben, David W. LaFleur, Yanggu Shi, Craig A. Rosen, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer
Trefoil domain-containing polynucleotides, polypeptides, and antibodies

Publication number: 20030166911

Abstract: The present invention relates to novel human TDC polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human TDC polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human TDC polypeptides.

Type: Application

Filed: October 9, 2002

Publication date: September 4, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Reinhard Ebner, Yanggu Shi, Steven M. Ruben
NK cell receptor polynucleotides, polypeptides, and antibodies

Publication number: 20030162175

Abstract: The present invention relates to novel human NKCR polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human NKCR polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human NKCR polypeptides.

Type: Application

Filed: June 27, 2001

Publication date: August 28, 2003

Inventors: Steven M. Ruben, Yanggu Shi
Human secreted proteins

Publication number: 20030152933

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Application

Filed: February 12, 2002

Publication date: August 14, 2003

Inventors: Steven C. Barash, Jian Ni, Steven M. Ruben, Craig A. Rosen, Yanggu Shi
Transferrin polynucleotides, polypeptides, and antibodies

Publication number: 20030149256

Abstract: The present invention relates to novel human transferrin polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human transferrin polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human transferrin polypeptides.

Type: Application

Filed: October 9, 2002

Publication date: August 7, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Steven M. Ruben, Yanggu Shi
101 human secreted proteins

Publication number: 20030144492

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: July 16, 2002

Publication date: July 31, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Roxanne Duan, Steven M. Ruben, Kimberly A. Florence, John M. Greene, Craig A. Rosen, Paul Young, Ann M. Ferrie, Guo-Liang Yu, Fouad Janat, Jian Ni, Kenneth C. Carter, Gregory A. Endress, Ping Feng, David W. Lafleur, Yanggu Shi
Secreted protein HODAZ50

Patent number: 6590075

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Grant

Filed: September 4, 1998

Date of Patent: July 8, 2003

Assignee: Human Genome Sciences, Inc.

Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Yanggu Shi
27 human secreted proteins

Publication number: 20030104400

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Application

Filed: January 18, 2002

Publication date: June 5, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Steven M. Ruben, Jian Ni, Reinhard Ebner, Craig A. Rosen, Yanggu Shi, Charles E. Birse, Kimberly A. Florence, George Komatsoulis, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Paul E. Young
97 human secreted proteins

Publication number: 20030100051

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Application

Filed: September 10, 2001

Publication date: May 29, 2003

Inventors: Steven M. Ruben, Kimberly A. Florence, Jian Ni, Craig A. Rosen, Kenneth C. Carter, Paul A. Moore, Henrik S. Olsen, Yanggu Shi, Paul E. Young, Ying-Fei Wei, Laurie A. Brewer, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, Charles E. Birse
Protein HLQDR48

Patent number: 6569992

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Grant

Filed: August 5, 1999

Date of Patent: May 27, 2003

Assignee: Human Genome Sciences, Inc.

Inventors: David W. LaFleur, Steven M. Ruben, Craig A. Rosen, Paul A. Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
44 human secreted proteins

Publication number: 20030096982

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: February 5, 2002

Publication date: May 22, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: David W. LaFleur, Steven M. Ruben, Craig A. Rosen, Paul A. Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
49 human secreted proteins

Patent number: 6566325

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Grant

Filed: July 16, 2001

Date of Patent: May 20, 2003

Assignee: Human Genome Sciences, Inc.

Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
Secreted protein HEMAE80

Publication number: 20030092893

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: December 20, 2001

Publication date: May 15, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Paul Young, John M. Greene, Ann M. Ferrie, Steven M. Ruben, Craig A. Rosen, Jing-Shan Hu, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, Charles Florence, Kimberly Florence, David W. Lafleur, Jian Ni, Ping Fan, Ying-Fei Wei, Carrie L. Fischer, Daniel R. Soppet, Yi Li, Zhizhen Zeng, Hla Kyaw, Guo-Liang Yu, Ping Feng, Patrick J. Dillon, Gregory A. Endress, Kenneth C. Carter
Cardiotrophin-like cytokine

Publication number: 20030087395

Abstract: The present invention relates to a novel CLC protein which is a member of the IL-6 cytokine family. In particular, isolated nucleic acid molecules are provided encoding the human CLC protein. CLC polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of CLC activity. Also provided are diagnostic methods for detecting cardiac and immune system-related disorders and therapeutic methods for treating cardiac and immune system-related disorders.

Type: Application

Filed: August 7, 2002

Publication date: May 8, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Yanggu Shi, Steven M. Ruben
125 HUMAN SECRETED PROTEINS

Publication number: 20030088078

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: May 5, 1999

Publication date: May 8, 2003

Inventors: STEVEN M. RUBEN, CRAIG A. ROSEN, YANGGU SHI
49 human secreted proteins

Publication number: 20030087341

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Application

Filed: January 25, 2002

Publication date: May 8, 2003

Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
97 human secreted proteins

Publication number: 20030077809

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: June 28, 2001

Publication date: April 24, 2003

Inventors: Steven M. Ruben, Kimberly Florence, Jian Ni, Craig A. Rosen, Kenneth C. Carter, Paul A. Moore, Henrik Olsen, Yanggu Shi, Paul Young, Ying-Fei Wei, Laurie A. Brewer, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner
47 human secreted proteins

Publication number: 20030078405

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.

Type: Application

Filed: July 2, 2001

Publication date: April 24, 2003

Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
70 human secreted proteins

Publication number: 20030069405

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: May 15, 2002

Publication date: April 10, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Steven M. Ruben, Paul E. Young, Laurie A. Brewer, Reinhard Ebner, Henrik S. Olsen, Kimberly A. Florence, Craig A. Rosen, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Charles Florence, Daniel R. Soppet, Gregory A. Endress, Ping Feng, George A. Komatsoulis
87 human secreted proteins

Publication number: 20030069406

Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.

Type: Application

Filed: May 13, 2002

Publication date: April 10, 2003

Applicant: Human Genome Sciences, Inc.

Inventors: Paul Young, John M. Greene, Ann M. Ferrie, Steven M. Ruben, Craig A. Rosen, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. Lafleur, Jian Ni

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