Patents by Inventor Yanggu Shi

Yanggu Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 17 human secreted proteins
    Publication number: 20050032168
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 23, 2004
    Publication date: February 10, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig Rosen, George Komatsoulis, Kevin Baker, Charles Birse, Daniel Soppet, Henrik Olsen, Paul Moore, Ping Wei, Reinhard Ebner, D. Duan, Yanggu Shi, Gil Choi, Michele Fiscella, Jian Ni, Steven Ruben, Steven Barash
  • Antibody to an IL-17 receptor like protein
    Patent number: 6849719
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating, diagnosing, detecting, and/or preventing immune system-related disorders.
    Type: Grant
    Filed: March 2, 2001
    Date of Patent: February 1, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • 52 Human secreted proteins
    Publication number: 20050019866
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 6, 2004
    Publication date: January 27, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Kevin Baker, Charles Birse, Michele Fiscella, George Komatsoulis, Craig Rosen, Daniel Soppet, Paul Young, Reinhard Ebner, D. Duan, Henrik Olsen, David La Fleur, Paul Moore, Yanggu Shi, Ping Wei, Kimberly Florence
  • 26 human secreted proteins
    Publication number: 20050010042
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 17, 2004
    Publication date: January 13, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Charles Birse, Roxanne Duan, Daniel Soppet, Craig Rosen, Yanggu Shi, David LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly Florence, Jian Ni, Paul Young
  • 44 Human secreted proteins
    Publication number: 20050009085
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: August 16, 2004
    Publication date: January 13, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • 47 human secreted proteins
    Publication number: 20040253684
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 7, 2004
    Publication date: December 16, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Reinhard Ebner, Craig A. Rosen, Gregory A. Endress, Daniel R. Soppet, Jian Ni, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Henrik S. Olsen, Kimberly A. Florence
  • 18 human secreted proteins
    Publication number: 20040235113
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 24, 2004
    Publication date: November 25, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Paul E. Young, Reinhard Ebner, Daniel R. Soppet, Steven M. Ruben
  • 125 human secreted proteins
    Publication number: 20040185440
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 28, 2001
    Publication date: September 23, 2004
    Inventors: Ping Feng, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Henrik S. Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter
  • Polynucleotides encoding a novel interleukin receptor termed interleukin-17 receptor-like protein
    Publication number: 20040175790
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
    Type: Application
    Filed: October 17, 2003
    Publication date: September 9, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • 101 human secreted proteins
    Publication number: 20040157258
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 15, 2004
    Publication date: August 12, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Roxanne Duan, Steven M. Ruben, Kimberly A. Florence, John M. Greene, Craig A. Rosen, Paul Young, Ann M. Ferrie, Guo-Liang Yu, Fouad Janat, Jian Ni, Kenneth C. Carter, Gregory A. Endress, Ping Feng, David W. Lafleur, Yanggu Shi
  • 62 human secreted proteins
    Publication number: 20040152164
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 12, 2004
    Publication date: August 5, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, George Komatsoulis, Craig A. Rosen, Daniel R. Soppet, Yanggu Shi, David W. LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Paul Young
  • Human protein tyrosine phosphatase polynucleotides, polypeptides, and antibodies
    Patent number: 6770466
    Abstract: The present invention relates to novel human PTPase polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human PTPase polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human PtPase polypeptides.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: August 3, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • 94 human secreted proteins
    Publication number: 20040146930
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • 19 human secreted proteins
    Publication number: 20040126801
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 12, 2003
    Publication date: July 1, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, D. Roxanne Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • Nucleic acids encoding human serpin polypeptide HMCIS41
    Patent number: 6753164
    Abstract: The present invention relates to novel human Serpin polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human Serpin polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human Serpin polypeptides.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: June 22, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, Yanggu Shi
  • Interleukin 17 receptor-like protein
    Publication number: 20040115698
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating, diagnosing, detecting, and/or preventing immune system-related disorders.
    Type: Application
    Filed: August 22, 2003
    Publication date: June 17, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • Lysyl-oxidase HOHEC84 polynucleotides
    Patent number: 6743613
    Abstract: The present invention relates to novel human BMP polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human BMP polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human BMP polypeptides.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: June 1, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, Yanggu Shi
  • ANTIBODIES AGAINST INTERLEUKIN-17 RECEPTOR LIKE PROTEIN
    Publication number: 20040096935
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating, diagnosing, detecting, and/or preventing immune system-related disorders.
    Type: Application
    Filed: March 2, 2001
    Publication date: May 20, 2004
    Inventors: Yanggu Shi, Steven M. Ruben
  • 31 human secreted proteins
    Publication number: 20040048294
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 27, 2003
    Publication date: March 11, 2004
    Applicant: Human Genome Sciences,Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Roxanne D. Duan, Yanggu Shi, David W. LaFleur, Paul E. Young, Jian Ni, George Komatsoulis, Gregory A. Endress, Daniel R. Soppet
  • 95 human secreted proteins
    Publication number: 20040048304
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: September 3, 2003
    Publication date: March 11, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Guo-Liang Yu, Paul Young, Ping Feng, Daniel R. Soppet, Ying-Fei Wei, Gregory A. Endress, Roxanne Duan, Hla Kyaw, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore