Patents by Inventor Yanggu Shi

Yanggu Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serine proteases
    Publication number: 20020119925
    Abstract: The present invention relates to novel human serine protease polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human serine protease polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human serine protease polypeptides.
    Type: Application
    Filed: September 6, 2001
    Publication date: August 29, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Yanggu Shi, Steven M. Ruben
  • Extracellular matrix polynucleotides, polypeptides, and antibodies
    Publication number: 20020106780
    Abstract: The present invention relates to novel human extracellular matrix polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human extracellular matrix polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human extracellular matrix polypeptides.
    Type: Application
    Filed: October 17, 2001
    Publication date: August 8, 2002
    Inventors: Michele Fiscella, Reinhard Ebner, Yanggu Shi, Steven M. Ruben
  • 186 human secreted proteins
    Patent number: 6420526
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: September 8, 1998
    Date of Patent: July 16, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel P. Soppet, Kenneth C. Carter, Daniel R. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. Lafleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • Four disulfide core domain-containing (FDCD) polynucleotides, polypeptides, and antibodies
    Publication number: 20020081607
    Abstract: The present invention relates to novel human FDCD polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human FDCD polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human FDCD polypeptides.
    Type: Application
    Filed: June 6, 2001
    Publication date: June 27, 2002
    Inventors: Steven M. Ruben, Yanggu Shi
  • ADAM polynucleotides, polypeptides, and antibodies
    Publication number: 20020077465
    Abstract: The present invention relates to novel human ADAM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ADAM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human ADAM polypeptides.
    Type: Application
    Filed: September 5, 2001
    Publication date: June 20, 2002
    Inventors: Yanggu Shi, Steven M. Ruben
  • 31 human secreted proteins
    Publication number: 20020076705
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 30, 2001
    Publication date: June 20, 2002
    Inventors: Steven M. Ruben, Craig A. Rosen, Roxanne D. Duan, Yanggu Shi, David W. LaFleur, Paul E. Young, Jian Ni, George Komatsoulis, Gregory A. Endress, Daniel R. Soppet
  • Transferrin polynucleotides, polypeptides, and antibodies
    Publication number: 20020072596
    Abstract: The present invention relates to novel human transferrin polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human transferrin polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human transferrin polypeptides.
    Type: Application
    Filed: June 26, 2001
    Publication date: June 13, 2002
    Inventors: Steven M. Ruben, Yanggu Shi
  • Serine protease polynucleotides, polypeptides, and antibodies
    Publication number: 20020068320
    Abstract: The present invention relates to novel human serine protease polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human serine protease polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human serine protease polypeptides.
    Type: Application
    Filed: March 13, 2001
    Publication date: June 6, 2002
    Inventors: Yanggu Shi, Steven M. Ruben, Jian Ni
  • Human protein tyrosine phosphatase polynucleotides, polypeptides, and antibodies
    Publication number: 20020064844
    Abstract: The present invention relates to novel human PTPase polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human PTPase polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human PTPase polypeptides.
    Type: Application
    Filed: July 18, 2001
    Publication date: May 30, 2002
    Inventors: Yanggu Shi, Steven M. Ruben
  • 52 human secreted proteins
    Publication number: 20020064818
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: February 22, 2001
    Publication date: May 30, 2002
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Michele Fiscella, George A. Komatsoulis, Craig A. Rosen, Daniel R. Soppet, Paul E. Young, Reinhard Ebner, D. Roxanne Duan, Henrik S. Olsen, David W. LaFleur, Paul A. Moore, Yanggu Shi, Ping Wei, Kimberly A. Florence
  • Cytokine receptor-like polynucleotides, polypeptides, and antibodies
    Publication number: 20020064826
    Abstract: The present invention relates to novel human cytokine receptor-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human cytokine receptor-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human cytokine receptor-like polypeptides.
    Type: Application
    Filed: June 6, 2001
    Publication date: May 30, 2002
    Inventors: Steven M. Ruben, Jian Ni, Paul E. Young, Yanggu Shi
  • Immunoglobulin superfamily polynucleotides, polypeptides, and antibodies
    Publication number: 20020065220
    Abstract: The present invention relates to novel human Ig-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human Ig-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human Ig-like polypeptides.
    Type: Application
    Filed: March 7, 2001
    Publication date: May 30, 2002
    Inventors: Paul E. Young, Jain Ni, Steven M. Ruben, Yanggu Shi
  • IL-6-like polynucleotides, polypeptides, and antibodies
    Publication number: 20020037523
    Abstract: The present invention relates to novel human IL-6-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human IL-6-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human IL-6-like polypeptides.
    Type: Application
    Filed: June 7, 2001
    Publication date: March 28, 2002
    Inventors: Steven M. Ruben, Yanggu Shi
  • 26 Human secreted proteins
    Publication number: 20020028449
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 1, 2000
    Publication date: March 7, 2002
    Inventors: Steven M. Ruben, Charles E. Birse, Roxanne D. Duan, Daniel R. Soppet, Craig A. Rosen, Yanggu Shi, David W. LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly A. Florence, Jian Ni, Paul Young
  • 49 human secreted proteins
    Publication number: 20020026040
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 16, 2001
    Publication date: February 28, 2002
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. LaFleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • 18 Human secreted proteins
    Publication number: 20020012966
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 25, 2001
    Publication date: January 31, 2002
    Inventors: Yanggu Shi, Paul E. Young, Reinhard Ebner, Daniel R. Soppet, Steven M. Ruben
  • Retinoid receptor interacting polynucleotides, polypeptides, and antibodies
    Publication number: 20020004489
    Abstract: The present invention relates to novel human RIP polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human RIP polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human RIP polypeptides.
    Type: Application
    Filed: February 21, 2001
    Publication date: January 10, 2002
    Inventors: Yanggu Shi, Steven M. Ruben
  • 49 human secreted proteins
    Publication number: 20010021700
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 19, 2000
    Publication date: September 13, 2001
    Inventors: Paul A. Moore, Steven M. Ruben, Henrik S. Olsen, Yanggu Shi, Craig A. Rosen, Kimberly A. Florence, Daniel R. Soppet, David W. Lafleur, Gregory A. Endress, Reinhard Ebner, George Komatsoulis, Roxanne D. Duan
  • Polynucleotides encoding a cardiotrophin-like cytokine
    Patent number: 6046035
    Abstract: The present invention relates to a novel CLC protein which is a member of the IL-6 cytokine family. In particular, isolated nucleic acid molecules are provided encoding the human CLC protein. CLC polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of CLC activity. Also provided are diagnostic methods for detecting cardiac and immune system-related disorders and therapeutic methods for treating cardiac and immune system-related disorders.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: April 4, 2000
    Assignee: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben