Patents by Inventor Yanggu Shi

Yanggu Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serine proteases
    Publication number: 20020192800
    Abstract: The present invention relates to novel human serine protease polypeptides and isolated nucleic acids containin g the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human serine protease polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human serine protease polypeptides.
    Type: Application
    Filed: April 19, 2002
    Publication date: December 19, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Yanggu Shi, Steven M. Ruben
  • ADAM polynucleotides, polypeptides, and antibodies
    Publication number: 20020182702
    Abstract: The present invention relates to novel human ADAM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ADAM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human ADAM polypeptides.
    Type: Application
    Filed: September 19, 2001
    Publication date: December 5, 2002
    Inventors: Steven M. Ruben, Jian Ni, Gregg A. Hastings, Yanggu Shi, Ping Wei
  • 26 human secreted proteins
    Publication number: 20020183503
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 11, 2002
    Publication date: December 5, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Charles E. Birse, Roxanne D. Duan, Daniel R. Soppet, Craig A. Rosen, Yanggu Shi, David W. LaFleur, Henrik Olsen, Reinhard Ebner, Kimberly A. Florence, Jian Ni, Paul Young
  • Protein tyrosine kinase receptor polynucleotides, polypeptides, and antibodies
    Publication number: 20020173458
    Abstract: The present invention relates to novel human PTK polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human PTK polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human PTK polypeptides.
    Type: Application
    Filed: April 18, 2001
    Publication date: November 21, 2002
    Inventors: Steven M. Ruben, Yanggu Shi, Paul E. Young, Jian Ni
  • ADAM polynucleotides, polypeptides, and antibodies
    Publication number: 20020173640
    Abstract: The present invention relates to novel human ADAM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ADAM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human ADAM polypeptides.
    Type: Application
    Filed: April 19, 2002
    Publication date: November 21, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Gregg A. Hastings, Yanggu Shi, Ping Wei
  • Interleukin 17-like receptor protein
    Patent number: 6482923
    Abstract: The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: November 19, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steve M. Ruben
  • ADAM polynucleotides, polypeptides, and antibodies
    Publication number: 20020165377
    Abstract: The present invention relates to novel human ADAM polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human ADAM polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human ADAM polypeptides.
    Type: Application
    Filed: April 19, 2002
    Publication date: November 7, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Ping Wei, Jian Ni, Gregg A. Hastings, Yanggu Shi
  • Steroid hormone receptor polynucleotides, polypeptides, and antibodies
    Publication number: 20020165384
    Abstract: The present invention relates to novel human steroid hormone receptor polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human steroid hormone receptor polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human steroid hormone receptor polypeptides.
    Type: Application
    Filed: March 22, 2002
    Publication date: November 7, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Yanggu Shi, Steven M. Ruben
  • TM4SF receptor polynucleotides, polypeptides, and antibodies
    Publication number: 20020164693
    Abstract: The present invention relates to novel human TM4SF polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human TM4SF polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human TM4SF polypeptides.
    Type: Application
    Filed: October 10, 2001
    Publication date: November 7, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • Secreted protein HFEAF41
    Publication number: 20020165374
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 29, 2001
    Publication date: November 7, 2002
    Inventors: Paul Young, John M. Greene, Ann M. Ferrie, Steven M. Ruben, Craig A. Rosen, Roxanne Duan, Jing-Shan Hu, Kimberly Florence, Henrik S. Olsen, Reinhard Ebner, Lauie A. Brewer, Paul A. Moore, Yanggu Shi, David W. Lafleur, Jian Ni
  • Secreted protein HRGDF73
    Publication number: 20020164669
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: October 19, 2001
    Publication date: November 7, 2002
    Inventors: Steven M. Ruben, Craig A. Rosen, Carrie L. Fischer, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Reinhard Ebner, Laurie A. Brewer, Yanggu Shi
  • 94 Human Secreted Proteins
    Patent number: 6475753
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. Lafleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Secreted protein HNFGF20
    Patent number: 6476195
    Abstract: The present invention relates to novel human secreted protein (HNFGF20). Polypeptides of the invention are duseful in dianosis and treatment of disorders affecting the immune system.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: November 5, 2002
    Assignee: Human Genome Sciences, Inc.
    Inventors: George Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Ying-Fei Wei, Jian Ni, Kimberly A. Florence, Paul Young, Laurie A. Brewer, Daniel R. Soppet, Gregory A. Endress, Reinhard Ebner, Henrik Olsen, Michael Mucenski
  • Human Serpin polynucleotides, polypeptides, and antibodies
    Publication number: 20020160491
    Abstract: The present invention relates to novel human Serpin polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human Serpin polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human Serpin polypeptides.
    Type: Application
    Filed: July 26, 2001
    Publication date: October 31, 2002
    Inventors: Jian Ni, Steven M. Ruben, Yanggu Shi
  • Calcium channel polynucleotides, polypeptides, and antibodies
    Publication number: 20020155539
    Abstract: The present invention relates to novel human calcium channel polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human calcium channel polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human calcium channel polypeptides.
    Type: Application
    Filed: January 18, 2002
    Publication date: October 24, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Yanggu Shi
  • Human polynucleotides, polypeptides, and antibodies
    Publication number: 20020151009
    Abstract: The present invention relates to novel human polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human polypeptides.
    Type: Application
    Filed: August 28, 2001
    Publication date: October 17, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Yanggu Shi, Reinhard Ebner, Steven M. Ruben
  • Bone morphogenic protein (BMP) polynucleotides, polypeptides, and antibodies
    Publication number: 20020143170
    Abstract: The present invention relates to novel human BMP polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human BMP polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human BMP polypeptides.
    Type: Application
    Filed: February 7, 2002
    Publication date: October 3, 2002
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Steven M. Ruben, Yanggu Shi
  • Trefoil domain-containing polynucleotides, polypeptides, and antibodies
    Publication number: 20020119519
    Abstract: The present invention relates to novel human TDC polypeptides and isolated nucliec acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human TDC olypeptides. The invention further relates to diagnostic and therapeutic methods for diagnosing and treating disorders related to these novel human TDC polypeptides.
    Type: Application
    Filed: June 26, 2001
    Publication date: August 29, 2002
    Inventors: Reinhard Ebner, Yanggu Shi, Steven M. Ruben
  • 17 human secreted proteins
    Publication number: 20020120103
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 27, 2001
    Publication date: August 29, 2002
    Inventors: Craig A. Rosen, George A. Komatsoulis, Kevin P. Baker, Charles E. Birse, Daniel R. Soppet, Henrik S. Olsen, Paul A. Moore, Ping Wei, Reinhard Ebner, D. Roxanne Duan, Yanggu Shi, Gil H. Choi, Michele Fiscella, Jian Ni, Steven M. Ruben, Steven C. Barash
  • Steroid hormone receptor polynucleotides, polypeptides, and antibodies
    Publication number: 20020120110
    Abstract: The present invention relates to novel human steroid hormone receptor polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human steroid hormone receptor polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human steroid hormone receptor polypeptides.
    Type: Application
    Filed: March 14, 2001
    Publication date: August 29, 2002
    Inventors: Jian Ni, Yanggu Shi, Steven M. Ruben