Abstract: A class of indole compounds is provided, their preparation methods and use thereof, which belong to the technical field of pharmaceutical chemistry. The compounds represented by formula I have a well therapeutic effect on atopic dermatitis.

Abstract: An agent for navigating a mobile automated system is disclosed herein. The navigation agent receives a navigation instruction and visual information for one or more observed images. The navigation agent is provided or equipped with self-awareness, which provides or supports the following abilities: identifying which direction to go or proceed by determining the part of the instruction that corresponds to the observed images (visual grounding), and identifying which part of the instruction has been completed or ongoing and which part is potentially needed for the next action selection (textual grounding). In some embodiments, the navigation agent applies regularization to ensures that the grounded instruction can correctly be used to estimate the progress made towards the navigation goal (progress monitoring).

Abstract: The invention relates, in particular, to a quantum-enabled server (S) comprising an enclave (SE), a qubit source (SS), and quantum-computing means (SM), this enclave comprising means for: receiving information from a remote client through a secured communication channel; determining transformation data from said information; transforming at least one qubit received from said qubit source, according to transformation data; providing the at least one transformed qubits to said quantum-computing means.

Abstract: Provided are a gamepad and a cooling method thereof, which relate to the technical field of electronic gaming devices. The gamepad includes a gamepad body, a cooling assembly, and a power interface. A main PCB and a cooling PCB that are selectively electrically connected to each other are disposed in the gamepad body, the gamepad does not include a power supply apparatus, and the main PCB is selectively electrically connected to an external electronic device. The cooling assembly is electrically connected to the cooling PCB.

Abstract: The disclosed embodiments are directed to a modular autonomous vehicle system comprising a blended wing body module, at least two high speed long range wing panel modules configured to interchangeably mount to the blended wing body module, at least two low speed high endurance wing panel modules configured to interchangeably mount to the blended wing body module, a vertical tails module configured to interchangeably mount to the blended wing body module, a vertical takeoff and landing fin module configured to interchangeably mount to the blended wing body module, a power train, and a wheels module with a plurality of wheels operably connected to the power train.

Abstract: Disclosed are a deuterated 1,4-benzodiazepine-2,5-dione compound and the use thereof. Provided is a compound as represented by formula I or a pharmaceutically acceptable salt thereof. The disclosed 1,4-benzodiazepine-2,5-dione active compound maintains the activity of inhibiting tumor cells and tumor stem cells, and prolongs the degradation function of in-vitro human liver microsomes on the compound, such that the half-life period is significantly prolonged, which provides a safer and more reliable candidate for developing new anti-tumor drugs.

Abstract: Methods and systems are described herein for a malware detection system that detects whether an on-chain program associated with a cryptographic token is malicious based on output of a machine learning model. The malware detection system may retrieve or generate attributes associated with an on-chain program and input those into a plurality of scripts within a malware detection script database to determine whether the on-chain program is malicious. The scripts may be generated based on an output of a machine learning model indicating whether the on-chain program is malicious.

Abstract: In some aspects, a computing system may use time series data and machine learning to determine an efficient time to send data to a blockchain. A machine learning model may use a variety of blockchain related data to predict a network usage costs for different times in the future. The predicted network usage costs may be used to determine when data should be sent for storing on the blockchain to reduce network resource costs for a computing system. For example, based on inputting the blockchain data into the machine learning model, a computing system may generate output indicating network usage costs for a future time period, with each network usage cost corresponding to a timestamp within the future time period. The computing system may determine a minimum network usage cost of the network usage costs and send data to a node in the blockchain network at the corresponding timestamp.

Abstract: Disclosed herein are carbon molecular sieves and methods of making the same through the pyrolysis of a polymer precursor in the presence of a reactive gas stream including a hydrogen source.

Abstract: A scooter including a frame and a casing. The casing covers an outer peripheral side of the frame and is made of plastics.

Abstract: An agent for navigating a mobile automated system is disclosed herein. The navigation agent receives a navigation instruction and visual information for one or more observed images. The navigation agent is provided or equipped with self-awareness, which provides or supports the following abilities: identifying which direction to go or proceed by determining the part of the instruction that corresponds to the observed images (visual grounding), and identifying which part of the instruction has been completed or ongoing and which part is potentially needed for the next action selection (textual grounding). In some embodiments, the navigation agent applies regularization to ensures that the grounded instruction can correctly be used to estimate the progress made towards the navigation goal (progress monitoring).

Abstract: An agent for navigating a mobile automated system is disclosed herein. The navigation agent receives a navigation instruction and visual information for one or more observed images. The navigation agent is provided or equipped with self-awareness, which provides or supports the following abilities: identifying which direction to go or proceed by determining the part of the instruction that corresponds to the observed images (visual grounding), and identifying which part of the instruction has been completed or ongoing and which part is potentially needed for the next action selection (textual grounding). In some embodiments, the navigation agent applies regularization to ensures that the grounded instruction can correctly be used to estimate the progress made towards the navigation goal (progress monitoring).

Abstract: The present invention is directed to methods of fabricating novel cross-linked membranes and to cross-linked membranes produced by the disclosed methods. Specifically, methods of fabricating cross-linked membranes according to the present invention may comprise direct crosslinking, crosslinking by addition of a small molecule, interfacial crosslinking of free-standing film, and interfacial crosslinking on a solid support.

Abstract: The present teachings relate to a fluoro-containing compound, a composition thereof, a method of using the compound or the composition in treating a disease, and a method of preparing the compound. In a particular example, the compound is chosen from Formulae 4, 4f, 7, 8, 9, 10, 11, or 12, or a salt thereof, or a solvate of any of the foregoing.

Abstract: Disclosed herein are carbon molecular sieves and methods of making the same through the pyrolysis of a polymer precursor in the presence of a reactive gas stream including a hydrogen source.

Abstract: An agent for navigating a mobile automated system is disclosed herein. The navigation agent receives a navigation instruction and visual information for one or more observed images. The navigation agent is provided or equipped with self-awareness, which provides or supports the following abilities: identifying which direction to go or proceed by determining the part of the instruction that corresponds to the observed images (visual grounding), and identifying which part of the instruction has been completed or ongoing and which part is potentially needed for the next action selection (textual grounding). In some embodiments, the navigation agent applies regularization to ensures that the grounded instruction can correctly be used to estimate the progress made towards the navigation goal (progress monitoring).

Abstract: Systems and methods for improving video understanding tasks based on higher-order object interactions (HOIs) between object features are provided. A plurality of frames of a video are obtained. A coarse-grained feature representation is generated by generating an image feature for each of for each of a plurality of timesteps respectively corresponding to each of the frames and performing attention based on the image features. A fine-grained feature representation is generated by generating an object feature for each of the plurality of timesteps and generating the HOIs between the object features. The coarse-grained and the fine-grained feature representations are concatenated to generate a concatenated feature representation.

Abstract: The present invention is directed to methods of fabricating novel cross-linked membranes and to cross-linked membranes produced by the disclosed methods. Specifically, methods of fabricating cross-linked membranes according to the present invention may comprise direct crosslinking, crosslinking by addition of a small molecule, interfacial crosslinking of free-standing film, and interfacial crosslinking on a solid support.

Abstract: Systems and methods for improving video understanding tasks based on higher-order object interactions (HOIs) between object features are provided. A plurality of frames of a video are obtained. A coarse-grained feature representation is generated by generating an image feature for each of for each of a plurality of timesteps respectively corresponding to each of the frames and performing attention based on the image features. A fine-grained feature representation is generated by generating an object feature for each of the plurality of timesteps and generating the HOIs between the object features. The coarse-grained and the fine-grained feature representations are concatenated to generate a concatenated feature representation.