Patents by Inventor Yao Ma

Yao Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3D DISPLAY PANEL AND PIXEL BRIGHTNESS CONTROL METHOD THEREOF
    Publication number: 20120320097
    Abstract: A 3D display panel includes a plurality of first and second viewing angle pixels arranged along a first direction for displaying first and second viewing angle images respectively. The first viewing angle pixels and the second viewing angle pixels are interlacedly arranged along a second direction. A method for controlling pixel brightness of the 3D display panel includes determining a brightness value of a first block of a first viewing angle pixel according to a brightness value of the first viewing angle pixel and a brightness value of a second viewing angle pixel next to the first viewing angle pixel along the second direction, and determining a brightness value of a second block of the first viewing angle pixel according to the brightness value of the first block of the first viewing angle pixel and the brightness value of the first viewing angle pixel.
    Type: Application
    Filed: October 30, 2011
    Publication date: December 20, 2012
    Inventors: Chih-Yao Ma, Yu-Cheng Chang, Yi-Pai Huang, Cheng-Han Tsao, Chao-Yuan Chen
  • SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF
    Publication number: 20120208844
    Abstract: The present invention provides a compound of Formula (1) as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
    Type: Application
    Filed: October 5, 2010
    Publication date: August 16, 2012
    Inventors: Stephane L. Bogen, Yao Ma, Yaolin Wang, Brian Robert Lahue, Latha G. Nair, Manami Shizuka, Matthew Ernst Voss, Margarita Kirova-Snover, Weidong Pan, Yuan Tian, Bheemashankar A. Kulkarni, Craig R. Gibeau, Yuan Liu, Giovanna Scapin, Diane Rindgen, Ronald J. Doll, Timothy J. Guzi, Danny J. Hicklin, Amin Nomeir, Cynthia Seidel-Dugan, Gerald W. Shipps, JR., Malcolm MacCoss
  • HDM2 polypeptides
    Patent number: 7888474
    Abstract: The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: February 15, 2011
    Assignee: Schering Corporation
    Inventors: Thomas E. Hesson, Hung V. Le, Yao Ma, Vincent S. Madison, Anthony F. Mannarino, Paul Reichert, Gerald W. Shipps, Jr., Corey O. Strickland, Shahriar Shane Taremi, Yaolin Wang, Rumin Zhang, Jose Duca
  • Substituted piperidines that increase P53 activity and the uses thereof
    Patent number: 7884107
    Abstract: In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: June 27, 2007
    Date of Patent: February 8, 2011
    Assignee: Merck
    Inventors: Yao Ma, Brian Robert Lahue, Gerald W. Shipps, Jr., Yaolin Wang, Stephane L. Bogen, Matthew Ernst Voss, Latha G. Nair, Yuan Tian, Ronald J. Doll, Zhuyan Guo, Corey O. Strickland, Rumin Zhang, Mark A. McCoy, Weidong Pan, Elise M. Siegel, Craig R. Gibeau
  • HDM2 POLYPEPTIDES
    Publication number: 20100267150
    Abstract: The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors.
    Type: Application
    Filed: March 12, 2010
    Publication date: October 21, 2010
    Inventors: THOMAS E. HESSON, HUNG V. LE, YAO MA, VINCENT S. MADISON, ANTHONY F. MANNARINO, PAUL REICHERT, GERALD W. SHIPPS, JR., COREY O. STRICKLAND, SHAHRIAR SHANE TAREMI, YAOLIN WANG, RUMIN ZHANG, JOSE DUCA
  • HDM2 Polypeptides
    Patent number: 7705127
    Abstract: The present invention relates to HDM2 polypeptides and mutants thereof which are complexed with various compounds, e.g., HDM2 inhibitors.
    Type: Grant
    Filed: October 10, 2008
    Date of Patent: April 27, 2010
    Assignee: Schering Corporation
    Inventors: Thomas E. Hesson, Hung V. Le, Yao Ma, Vincent S. Madison, Anthony F. Mannarino, Paul Reichert, Gerald W. Shipps, Jr., Corey O. Strickland, Shahriar Shane Taremi, Yaolin Wang, Rumin Zhang, Jose Duca
  • Method of Using Substituted Piperidines that Increase P53 Activity
    Publication number: 20080004286
    Abstract: The present invention discloses a method of using compounds, which have HDM2 protein antagonist activity, to treat or prevent cancer, other diseases caused by abnormal cell proliferation, diseases associated with HDM2, or diseases caused by inadequate P53 activity.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Inventors: Yaolin Wang, Rumin Zhang, Yao Ma, Brian Robert Lahue, Gerald W. Shipps
  • Substituted Piperidines that Increase P53 Activity and the Uses Thereof
    Publication number: 20080004287
    Abstract: In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 3, 2008
    Inventors: Yao Ma, Brian Lahue, Gerald Shipps, Yaolin Wang, Stephane Bogen, Matthew Voss, Latha Nair, Yuan Tian, Ronald Doll, Zhuyan Guo, Corey Strickland, Rumin Zhang, Mark McCoy, Weidong Pan, Elise Siegel, Craig Gibeau