Patents by Inventor Yao Ma

Yao Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9785677
    Abstract: Disclosed is a micro-blog sorting method, in which micro-blog information requested by a micro-blog requesting user is acquired, micro-blog posting user information and content information are extracted from the micro-blog information to score the micro-blog information, the micro-blog information is sorted according to the score and the micro-blog information is presented according to a sorted result. With the above micro-blog sorting method, the micro-blog posting user information as well as the content information in the micro-blog information are extracted to score the micro-blog information, the micro-blog information is sorted according to the score, and the micro-blog information related to the user is sorted close to the top, and thus it is convenient for the user to view the micro-blog information. In addition, a micro-blog sorting system and a micro-blog searching and presenting method and system are also provided.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: October 10, 2017
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventor: Yao Ma
  • Publication number: 20170283960
    Abstract: The present teachings relate to a methods for drug discovery. In one particular example, the method includes providing a substrate, modifying the substrate by using an electrochemical fluorination, screening a reaction mixture of the electrochemical fluorination, and identifying a fluorinated compound in the reaction mixture.
    Type: Application
    Filed: June 20, 2017
    Publication date: October 5, 2017
    Applicant: SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD.
    Inventors: Yao MA, Qing LIANG, Weilin LI, Yu TANG, Weidong WEN
  • Patent number: 9678675
    Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: June 13, 2017
    Assignee: International Business Machines Corporation
    Inventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
  • Publication number: 20160231931
    Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.
    Type: Application
    Filed: April 15, 2016
    Publication date: August 11, 2016
    Inventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
  • Patent number: 9389798
    Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: July 12, 2016
    Assignee: International Business Machines Corporation
    Inventors: Hui Xiang Gu, Yao Ma, Shu Yang, Jun Wei Zhang
  • Patent number: 9361216
    Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: June 7, 2016
    Assignee: International Business Machines Corporation
    Inventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
  • Publication number: 20160077763
    Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 17, 2016
    Inventors: Hu Xiang Gu, Yao Ma, Shu Yang, Jun Wei Zhang
  • Patent number: 9229849
    Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: January 5, 2016
    Assignee: International Business Machines Corporation
    Inventors: Shu Yang, Yao Ma, Hui Xiang Gu, Jun Wei Zhang
  • Patent number: 9085605
    Abstract: The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as shown by formula I. Specifically, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: July 21, 2015
    Assignee: Shenzhen Salubris Pharmaceuticals Co., Ltd.
    Inventors: Gang Liu, Nan Zhao, Yao Ma
  • Patent number: 9062071
    Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: June 23, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Yao Ma, Manami Shizuka, Timothy J. Guzi, Yuan Liu, Yuan Tian, Brian R. Lahue, Craig R. Gibeau, Gerald W. Shipps, Jr., Yaolin Wang, Stephane L. Bogen, Latha G. Nair, Weidong Pan, Mark A. McCoy, Matthew E. Voss, Margarita Kirova-Snover, W. Bent Clayton
  • Patent number: 8987274
    Abstract: The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: March 24, 2015
    Assignee: Merck Sharp & Dohme Corp
    Inventors: Latha G. Nair, Stephane L. Bogen, Ronald J. Doll, Yao Ma, Yuan Tian
  • Publication number: 20140336222
    Abstract: The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
    Type: Application
    Filed: July 24, 2014
    Publication date: November 13, 2014
    Inventors: Stephane L. Bogen, Yao Ma, Yaolin Wang, Brian Robert Lahue, Latha G. Nair, Manami Shizuka, Matthew E. Voss, Margarita Kirova-Snover, Weidong Pan, Yuan Tian, Bheemashankar A. Kulkarni, Craig R. Gibeau, Yuan Liu, Giovanna Scapin, Diane Rindgen, Ronald J. Doll, Timothy J. Guzi, Danny J. Hicklin, Amin Nomeir, Cynthia Seidel-Dugan, Gerald W. Shipps, JR., Malcolm MacCoss
  • Publication number: 20140323482
    Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
    Type: Application
    Filed: December 17, 2012
    Publication date: October 30, 2014
    Inventors: Yao Ma, Manami Shizuka, Timothy J. Guzi, Yuan Liu, Yuan Tian, Brian R. Lahue, Craig R. Gibeau, Gerald W. Shipps, JR., Yaolin Wang, Stephane L. Bogen, Latha G. Nair, Weidong Pan, Mark A. McCoy, Matthew E. Voss, Margarita Kirova-Snover, W. Bent Clayton
  • Patent number: 8872866
    Abstract: A 3D display panel includes a plurality of first and second viewing angle pixels arranged along a first direction for displaying first and second viewing angle images respectively. The first viewing angle pixels and the second viewing angle pixels are interlacedly arranged along a second direction. A method for controlling pixel brightness of the 3D display panel includes determining a brightness value of a first block of a first viewing angle pixel according to a brightness value of the first viewing angle pixel and a brightness value of a second viewing angle pixel next to the first viewing angle pixel along the second direction, and determining a brightness value of a second block of the first viewing angle pixel according to the brightness value of the first block of the first viewing angle pixel and the brightness value of the first viewing angle pixel.
    Type: Grant
    Filed: October 30, 2011
    Date of Patent: October 28, 2014
    Assignee: AU Optronics Corp.
    Inventors: Chih-Yao Ma, Yu-Cheng Chang, Yi-Pai Huang, Cheng-Han Tsao, Chao-Yuan Chen
  • Publication number: 20140315916
    Abstract: The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
    Type: Application
    Filed: October 23, 2012
    Publication date: October 23, 2014
    Inventors: Latha G. Nair, Stephane L. Bogen, Ronald J. Doll, Yao Ma, Yuan Tian
  • Patent number: 8859776
    Abstract: The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: October 14, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Stephane L. Bogen, Yao Ma, Yaolin Wang, Brian Robert Lahue, Latha G. Nair, Manami Shizuka, Matthew Ernst Voss, Margarita Kirova-Snover, Weidong Pan, Yuan Tian, Bheemashankar A. Kulkarni, Craig R. Gibeau, Yuan Liu, Giovanna Scapin, Diane Rindgen, Ronald J. Doll, Timothy J. Guzi, Danny J. Hicklin, Amin Nomeir, Gerald W. Shipps, Jr., Malcolm MacCoss
  • Publication number: 20140108388
    Abstract: Disclosed is a micro-blog sorting method, in which micro-blog information requested by a micro-blog requesting user is acquired, micro-blog posting user information and content information are extracted from the micro-blog information to score the micro-blog information, the micro-blog information is sorted according to the score and the micro-blog information is presented according to a sorted result. With the above micro-blog sorting method, the micro-blog posting user information as well as the content information in the micro-blog information are extracted to score the micro-blog information, the micro-blog information is sorted according to the score, and the micro-blog information related to the user is sorted close to the top, and thus it is convenient for the user to view the micro-blog information. In addition, a micro-blog sorting system and a micro-blog searching and presenting method and system are also provided.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Inventor: Yao Ma
  • Publication number: 20140068221
    Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.
    Type: Application
    Filed: August 7, 2013
    Publication date: March 6, 2014
    Applicant: International Business Machines Corporation
    Inventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
  • Publication number: 20130297905
    Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.
    Type: Application
    Filed: March 29, 2013
    Publication date: November 7, 2013
    Inventors: Shu Yang, Yao Ma, Hu Xiang Gu, Jun Wei Zhang
  • Publication number: 20130143826
    Abstract: The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as shown by formula I. Specifically, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.
    Type: Application
    Filed: May 27, 2011
    Publication date: June 6, 2013
    Inventors: Gang Liu, Nan Zhao, Yao Ma