Abstract: The present invention is directed to methods of fabricating novel cross-linked membranes and to cross-linked membranes produced by the disclosed methods. Specifically, methods of fabricating cross-linked membranes according to the present invention may comprise direct crosslinking, crosslinking by addition of a small molecule, interfacial crosslinking of free-standing film, and interfacial crosslinking on a solid support.

Abstract: The present teachings relate to a fluoro-containing compound, a composition thereof, a method of using the compound or the composition in treating a disease, and a method of preparing the compound. In a particular example, the compound is chosen from Formulae 4, 4f, 7, 8, 9, 10, 11, or 12, or a salt thereof, or a solvate of any of the foregoing.

Abstract: Disclosed herein are carbon molecular sieves and methods of making the same through the pyrolysis of a polymer precursor in the presence of a reactive gas stream including a hydrogen source.

Abstract: An agent for navigating a mobile automated system is disclosed herein. The navigation agent receives a navigation instruction and visual information for one or more observed images. The navigation agent is provided or equipped with self-awareness, which provides or supports the following abilities: identifying which direction to go or proceed by determining the part of the instruction that corresponds to the observed images (visual grounding), and identifying which part of the instruction has been completed or ongoing and which part is potentially needed for the next action selection (textual grounding). In some embodiments, the navigation agent applies regularization to ensures that the grounded instruction can correctly be used to estimate the progress made towards the navigation goal (progress monitoring).

Abstract: Systems and methods for improving video understanding tasks based on higher-order object interactions (HOIs) between object features are provided. A plurality of frames of a video are obtained. A coarse-grained feature representation is generated by generating an image feature for each of for each of a plurality of timesteps respectively corresponding to each of the frames and performing attention based on the image features. A fine-grained feature representation is generated by generating an object feature for each of the plurality of timesteps and generating the HOIs between the object features. The coarse-grained and the fine-grained feature representations are concatenated to generate a concatenated feature representation.

Abstract: The present invention is directed to methods of fabricating novel cross-linked membranes and to cross-linked membranes produced by the disclosed methods. Specifically, methods of fabricating cross-linked membranes according to the present invention may comprise direct crosslinking, crosslinking by addition of a small molecule, interfacial crosslinking of free-standing film, and interfacial crosslinking on a solid support.

Abstract: Systems and methods for improving video understanding tasks based on higher-order object interactions (HOIs) between object features are provided. A plurality of frames of a video are obtained. A coarse-grained feature representation is generated by generating an image feature for each of for each of a plurality of timesteps respectively corresponding to each of the frames and performing attention based on the image features. A fine-grained feature representation is generated by generating an object feature for each of the plurality of timesteps and generating the HOIs between the object features. The coarse-grained and the fine-grained feature representations are concatenated to generate a concatenated feature representation.

Abstract: Disclosed is a micro-blog sorting method, in which micro-blog information requested by a micro-blog requesting user is acquired, micro-blog posting user information and content information are extracted from the micro-blog information to score the micro-blog information, the micro-blog information is sorted according to the score and the micro-blog information is presented according to a sorted result. With the above micro-blog sorting method, the micro-blog posting user information as well as the content information in the micro-blog information are extracted to score the micro-blog information, the micro-blog information is sorted according to the score, and the micro-blog information related to the user is sorted close to the top, and thus it is convenient for the user to view the micro-blog information. In addition, a micro-blog sorting system and a micro-blog searching and presenting method and system are also provided.

Abstract: The present teachings relate to a methods for drug discovery. In one particular example, the method includes providing a substrate, modifying the substrate by using an electrochemical fluorination, screening a reaction mixture of the electrochemical fluorination, and identifying a fluorinated compound in the reaction mixture.

Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.

Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.

Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.

Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.

Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.

Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.

Abstract: The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as shown by formula I. Specifically, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.

Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.

Abstract: The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.

Abstract: The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.

Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.