Patents by Inventor Yao Ma
Yao Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9785677Abstract: Disclosed is a micro-blog sorting method, in which micro-blog information requested by a micro-blog requesting user is acquired, micro-blog posting user information and content information are extracted from the micro-blog information to score the micro-blog information, the micro-blog information is sorted according to the score and the micro-blog information is presented according to a sorted result. With the above micro-blog sorting method, the micro-blog posting user information as well as the content information in the micro-blog information are extracted to score the micro-blog information, the micro-blog information is sorted according to the score, and the micro-blog information related to the user is sorted close to the top, and thus it is convenient for the user to view the micro-blog information. In addition, a micro-blog sorting system and a micro-blog searching and presenting method and system are also provided.Type: GrantFiled: December 17, 2013Date of Patent: October 10, 2017Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITEDInventor: Yao Ma
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Publication number: 20170283960Abstract: The present teachings relate to a methods for drug discovery. In one particular example, the method includes providing a substrate, modifying the substrate by using an electrochemical fluorination, screening a reaction mixture of the electrochemical fluorination, and identifying a fluorinated compound in the reaction mixture.Type: ApplicationFiled: June 20, 2017Publication date: October 5, 2017Applicant: SHANXI CHEMICAL RESEARCH INSTITUTE CO., LTD.Inventors: Yao MA, Qing LIANG, Weilin LI, Yu TANG, Weidong WEN
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Patent number: 9678675Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.Type: GrantFiled: April 15, 2016Date of Patent: June 13, 2017Assignee: International Business Machines CorporationInventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
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Publication number: 20160231931Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.Type: ApplicationFiled: April 15, 2016Publication date: August 11, 2016Inventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
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Patent number: 9389798Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.Type: GrantFiled: November 25, 2015Date of Patent: July 12, 2016Assignee: International Business Machines CorporationInventors: Hui Xiang Gu, Yao Ma, Shu Yang, Jun Wei Zhang
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Patent number: 9361216Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.Type: GrantFiled: August 7, 2013Date of Patent: June 7, 2016Assignee: International Business Machines CorporationInventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
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Publication number: 20160077763Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.Type: ApplicationFiled: November 25, 2015Publication date: March 17, 2016Inventors: Hu Xiang Gu, Yao Ma, Shu Yang, Jun Wei Zhang
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Patent number: 9229849Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.Type: GrantFiled: March 29, 2013Date of Patent: January 5, 2016Assignee: International Business Machines CorporationInventors: Shu Yang, Yao Ma, Hui Xiang Gu, Jun Wei Zhang
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Patent number: 9085605Abstract: The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as shown by formula I. Specifically, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.Type: GrantFiled: May 27, 2011Date of Patent: July 21, 2015Assignee: Shenzhen Salubris Pharmaceuticals Co., Ltd.Inventors: Gang Liu, Nan Zhao, Yao Ma
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Patent number: 9062071Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.Type: GrantFiled: December 17, 2012Date of Patent: June 23, 2015Assignee: Merck Sharp & Dohme Corp.Inventors: Yao Ma, Manami Shizuka, Timothy J. Guzi, Yuan Liu, Yuan Tian, Brian R. Lahue, Craig R. Gibeau, Gerald W. Shipps, Jr., Yaolin Wang, Stephane L. Bogen, Latha G. Nair, Weidong Pan, Mark A. McCoy, Matthew E. Voss, Margarita Kirova-Snover, W. Bent Clayton
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Patent number: 8987274Abstract: The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.Type: GrantFiled: October 23, 2012Date of Patent: March 24, 2015Assignee: Merck Sharp & Dohme CorpInventors: Latha G. Nair, Stephane L. Bogen, Ronald J. Doll, Yao Ma, Yuan Tian
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Publication number: 20140336222Abstract: The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.Type: ApplicationFiled: July 24, 2014Publication date: November 13, 2014Inventors: Stephane L. Bogen, Yao Ma, Yaolin Wang, Brian Robert Lahue, Latha G. Nair, Manami Shizuka, Matthew E. Voss, Margarita Kirova-Snover, Weidong Pan, Yuan Tian, Bheemashankar A. Kulkarni, Craig R. Gibeau, Yuan Liu, Giovanna Scapin, Diane Rindgen, Ronald J. Doll, Timothy J. Guzi, Danny J. Hicklin, Amin Nomeir, Cynthia Seidel-Dugan, Gerald W. Shipps, JR., Malcolm MacCoss
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Publication number: 20140323482Abstract: The present invention provides a compound of Formula I (The formula should be inserted here) as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.Type: ApplicationFiled: December 17, 2012Publication date: October 30, 2014Inventors: Yao Ma, Manami Shizuka, Timothy J. Guzi, Yuan Liu, Yuan Tian, Brian R. Lahue, Craig R. Gibeau, Gerald W. Shipps, JR., Yaolin Wang, Stephane L. Bogen, Latha G. Nair, Weidong Pan, Mark A. McCoy, Matthew E. Voss, Margarita Kirova-Snover, W. Bent Clayton
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Patent number: 8872866Abstract: A 3D display panel includes a plurality of first and second viewing angle pixels arranged along a first direction for displaying first and second viewing angle images respectively. The first viewing angle pixels and the second viewing angle pixels are interlacedly arranged along a second direction. A method for controlling pixel brightness of the 3D display panel includes determining a brightness value of a first block of a first viewing angle pixel according to a brightness value of the first viewing angle pixel and a brightness value of a second viewing angle pixel next to the first viewing angle pixel along the second direction, and determining a brightness value of a second block of the first viewing angle pixel according to the brightness value of the first block of the first viewing angle pixel and the brightness value of the first viewing angle pixel.Type: GrantFiled: October 30, 2011Date of Patent: October 28, 2014Assignee: AU Optronics Corp.Inventors: Chih-Yao Ma, Yu-Cheng Chang, Yi-Pai Huang, Cheng-Han Tsao, Chao-Yuan Chen
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Publication number: 20140315916Abstract: The present invention provides a compound of Formula (1): as described herein or a pharmaceutically acceptable salt or solvate thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.Type: ApplicationFiled: October 23, 2012Publication date: October 23, 2014Inventors: Latha G. Nair, Stephane L. Bogen, Ronald J. Doll, Yao Ma, Yuan Tian
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Patent number: 8859776Abstract: The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.Type: GrantFiled: October 5, 2010Date of Patent: October 14, 2014Assignee: Merck Sharp & Dohme Corp.Inventors: Stephane L. Bogen, Yao Ma, Yaolin Wang, Brian Robert Lahue, Latha G. Nair, Manami Shizuka, Matthew Ernst Voss, Margarita Kirova-Snover, Weidong Pan, Yuan Tian, Bheemashankar A. Kulkarni, Craig R. Gibeau, Yuan Liu, Giovanna Scapin, Diane Rindgen, Ronald J. Doll, Timothy J. Guzi, Danny J. Hicklin, Amin Nomeir, Gerald W. Shipps, Jr., Malcolm MacCoss
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Publication number: 20140108388Abstract: Disclosed is a micro-blog sorting method, in which micro-blog information requested by a micro-blog requesting user is acquired, micro-blog posting user information and content information are extracted from the micro-blog information to score the micro-blog information, the micro-blog information is sorted according to the score and the micro-blog information is presented according to a sorted result. With the above micro-blog sorting method, the micro-blog posting user information as well as the content information in the micro-blog information are extracted to score the micro-blog information, the micro-blog information is sorted according to the score, and the micro-blog information related to the user is sorted close to the top, and thus it is convenient for the user to view the micro-blog information. In addition, a micro-blog sorting system and a micro-blog searching and presenting method and system are also provided.Type: ApplicationFiled: December 17, 2013Publication date: April 17, 2014Inventor: Yao Ma
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Publication number: 20140068221Abstract: A mechanism is provided for thin provisioning. An original time-domain sequence of a load parameter of storage resources already allocated to an application program is collected. A future load peak time period of the storage resources already allocated to the application program is determined based on the collected original time-domain sequence of the load parameter. A new storage resource unit from a high-speed storage is allocated in response to receipt of a request to allocate the new storage resource unit to the application program in the future load peak time period. On an occasion of thin provisioning, whether the physical storage resources newly allocated to the application program are located in a low-speed storage or a high-speed storage is determined according to the accesses of the application program to the already-allocated physical storage resources.Type: ApplicationFiled: August 7, 2013Publication date: March 6, 2014Applicant: International Business Machines CorporationInventors: Kuan Feng, Hui X. Gu, Yao Ma, Shu Yang, Jun W. Zhang
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Publication number: 20130297905Abstract: A storage system is dynamically reconfigured. The storage system includes storage pools that each include one or more storage disks. Storage pools to be expanded are determined as target storage pools. For the target storage pools, source storage disks to be moved into the target storage pools are determined from other storage pools than the target storage pools in the storage system. The source storage disks are migrated to the respective target storage pools.Type: ApplicationFiled: March 29, 2013Publication date: November 7, 2013Inventors: Shu Yang, Yao Ma, Hu Xiang Gu, Jun Wei Zhang
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Publication number: 20130143826Abstract: The present invention discloses chemical synthesis, anti-tumor and anti-metastatic effects of a dual functional conjugate as shown by formula I. Specifically, paclitaxel or docetaxol is linked with muramyl dipeptide derivative to form a conjugate, thus dual anti-tumor and anti-metastatic effects are achieved by combination of chemotherapy and immunotherapy. The present invention also discloses that paclitaxel or docetaxol and muramyl dipeptide derivative conjugate is synthesized by combination of solid-phase and solution-phase synthesis, and said conjugate can be used in manufacture of anti-tumor medicaments as proved by reliable bioassays.Type: ApplicationFiled: May 27, 2011Publication date: June 6, 2013Inventors: Gang Liu, Nan Zhao, Yao Ma