Abstract: A method and an apparatus for predicting a progression trend of a rare disease, an electronic device, and a medium are provided. The method includes: partitioning all medical examination data based on data characteristics of all the medical examination data in a current time period, so as to obtain medical examination data in multiple target time periods; inputting the medical examination data in each target time period into a disease index determination model corresponding to the rare disease type, respectively, so as to obtain a disease index corresponding to each target time period; generating a target trend polyline by taking the target time period as abscissa, and corresponding disease index as ordinate; calculating a similarity between the target trend polyline and each reference trend polyline; and determining the progression trend for the rare disease type in the rare disease patient based on the similarity.

Abstract: Provided a display panel and a display device. The display panel has a first display region including a light-transmitting region. The display panel includes a display function layer including light-emitting elements, a color filter layer arranged on a side of the display function layer facing towards a display surface of the display panel, and auxiliary structures that are nonopaque and arranged on the side of the display function layer facing towards the display surface of the display panel. The color filter layer includes color resists corresponding to the light-emitting elements. The auxiliary structure is at least located between adjacent color resists, and overlaps with the light-transmitting region. The display device includes the display panel.

Abstract: The present disclosure provides a medical image semantic segmentation method and apparatus, an electronic device, and a storage medium. The method includes: extracting, through a feature extraction network, a first image feature corresponding to a first image and multiple second image features corresponding to at least one second image, respectively; performing feature cross-alignment between the first image feature and a mean of the multiple second image features, so as to obtain multiple cross features; performing optimization on the multiple cross features, respectively, based on a similarity between the first image feature and the multiple second image features, so as to acquire multiple optimized features; fusing, through a decoder, the first image feature, the multiple optimized features, and masks matching each optimized feature, so as to obtain a mask result corresponding to the first image.

Abstract: Drive circuit and method, scanning circuit and method, and display device are provided. The drive circuit includes a shift register sub-circuit and an output sub-circuit. The shift register sub-circuit outputs a first level from a first level terminal based on an effective level of a second control clock signal, outputs an ineffective level of a first control clock signal based on effective levels of a third control clock signal and a turn-on control signal and subsequently outputs an effective level of the first control clock signal. The output sub-circuit outputs the first level based on the effective level of the first control clock signal output by the shift register sub-circuit, and outputs a second level based on an effective level of an interval clock signal.

Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.

Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.

Abstract: A processing system and method for rare-disease medical data are provided, where a server, based on a medical data analysis request initiated by a target client, generates global model parameters and an initial analysis model, and sends the global model parameters and the initial analysis model to a plurality of clients; each client trains the initial analysis model based on client-side medical data of the client, and sends local model parameters and loss function values of the local analysis model to the server; the server inputs a plurality of the local model parameters and the loss function values received in a current round into a particle swarm optimization model, so as to obtain optimized model parameters output by the particle swarm optimization model; the server determines whether the optimized model parameters meet a preset condition, wherein if no, the optimized model parameters are sent to each client.

Abstract: The present disclosure belongs to the field of biotechnology, and specifically relates to a seven-component antigen African swine fever subunit vaccine. The present disclosure first provides an African swine fever virus antigen protein combination composed of the African swine fever virus P34 protein, P30 protein, P54 protein, A104R protein, C129R protein, X protein, and Y protein. This African swine fever virus antigen protein combination can induce a strong immune response in the host. Furthermore, the present disclosure provides a seven-component antigen African swine fever subunit vaccine including the aforementioned African swine fever virus antigen protein combination.

Abstract: The present disclosure belongs to the field of biotechnology, and specifically relates to a nine-component antigen African swine fever subunit vaccine. The present disclosure first provides an African swine fever virus antigen protein combination composed of the African swine fever virus P34 protein, P30 protein, P54 protein, A104R protein, E165R protein, C129R protein, P72 protein, X protein, and Y protein. This African swine fever virus antigen protein combination can induce a strong immune response in the host. Furthermore, the present disclosure provides a nine-component antigen African swine fever subunit vaccine including the aforementioned African swine fever virus antigen protein combination.

Abstract: A display panel includes a transparent display area, a wiring area, a transitional display area, and a regular display area, where the transitional display area at least partially surrounds the transparent display area, the wiring area is located between the transparent display area and the transitional display area and between the transitional display area and the regular display area, the regular display area at least partially surrounds the transitional display area and the transparent display area, and a light transmittance of the transparent display area is greater than that of the regular display area. Along a first direction, the transitional display area is located between the first regular display area and the transparent display area. Along a second direction, a difference between the numbers of levels of the pixel-driving circuit in the first regular display area and the transitional display area is less than a predefined number of levels.

Abstract: A genetically engineered live bacterium comprising at least one effector gene that encodes a medical effector and at least one gene modification that shortens the bacterium's lifespan. After being administered to a subject, the bacterium survives within a time sufficient to allow the medical effector to exert at least one medical action and dies within a time sufficient to minimize pathogenesis to the subject. The bacterium provides an effective treatment of diseases or improving conditions while ensuring the biosafety for medical use.

Abstract: Methods and systems for real-time identification of media trends at a content sharing platform are provided. Embeddings representing features of a media item identified during a current time window are generated. Based on these embeddings, the system determines whether the similarity between the features of the media item and those of one or more additional media items identified during the same time window meets predefined similarity criteria. If the similarity criteria are satisfied, the media item and the additional media items are determined to correspond to an emerging media trend on the platform. An indication of this emerging media trend is then provided to a user of the platform via a client device during the current time window.

Abstract: A semiconductor device includes a die pad, a bond post, a die disposed over the die pad, a wire coupled between the die and the bond post and having a first portion bonded to the die at a first bond area and a second portion bonded to the bond post at a second bond area, a first bonding cover disposed over the first portion, and a second bonding cover disposed over the second portion. A method includes bonding a first portion of a wire to a die at a first bond area, bonding a second portion of the wire to a first bond post of a lead frame at a second bond area, applying a bonding material over the first bond area to form a first bonding cover, and applying the bonding material over the second bond area to form a second bonding cover.

Abstract: The present application discloses a display panel and a display device. The driver assembly is disposed in a bonding region and includes a first output unit. The multiplex circuit is disposed in a circuit region and includes a first circuit unit. The connection line is connected between the driver assembly and the multiplex circuit and includes a first connection line is connected between the first circuit unit and the first output unit. A plurality of pixel units are disposed in a display region and is connected to the multiplex circuit. The first connection line includes winding line segments distributed in the display region.

Abstract: Methods and systems for media trend identification of content sharing platforms are provided herein. A set of audiovisual embeddings that represent audiovisual features of a media item is obtained. A set of textual embeddings that represent textual features of the media item is obtained. The obtained set of audiovisual embeddings and the obtained set of textual embeddings are provided as an input to an artificial intelligence (AI) model trained to predict whether a respective media item is associated with one or more media trends of a platform based on given embeddings for the media item. One or more outputs of the AI model are obtained. A determination is made, based on the one or more outputs of the AI model, whether the media item is associated with the one or more media trends of the platform.

Abstract: Methods and systems for media trend detection and maintenance are provided herein. A set of media items each having common media characteristics is identified. A set of pose values is determined for each respective media item of the set of media items. Each pose value is associated with a particular predefined pose for objects depicted by the set of media items. A set of distance scores is calculated. Each distance score represents a distance between the respective set of pose values determined for a media item and a respective set of pose values determined for an additional media item. A coherence score is determined for the set of media items based on the calculated set of distance scores. Responsive to a determination that the coherence score satisfies one or more coherence criteria, a determination is made that the set of media items corresponds to a media trend of a platform.

Abstract: Methods and systems for visualizing media trends at a content sharing platform are provided herein. A request of a client device is received for media items of a platform. A graphical user interface (GUI) including audiovisual content of one or more media items and an indication that the media items are associated with a media trend of the platform is provided for presentation on the client device. The media trend is associated with a set of media items, where content of the set of media items share common audiovisual characteristics in accordance with a concept of the media trend A user interaction with a GUI element associated with the media items is detected. Responsive to the detection, an additional GUI is provided for presentation on to the client device, the additional GUI including audiovisual content of a set of media items associated with the media trend.

Abstract: A method for piloting from bypass in a network based on a satellite load platform can unify the influence of distance change and Doppler frequency shift of satellite ground stations in the whole network, and realize accurate quasi synchronization between the clock of the whole network and the clock of the satellite. The method includes transmitting a pilot signal from bypass based on a satellite load platform in a satellite communication system, taking a spaceborne high stability timing clock source as a reference, and transmitting the pilot signal to all downlink beams to provide the pilot signal for all satellite stations covered by the satellite.

Abstract: A method for quasi-synchronous code division multiple access based on synchronization clock by piloting can make CDMA operate in quasi-synchronous conditions, so it is suitable for open wireless channels with relay nodes, such as satellite communication systems, and open wireless channels without relay nodes. The method includes: adopting a mode of CDMA spread spectrum transmission to share power resources to transmit signals at multiple transmitting stations in open wireless channels; adopting an external pilot signal to provide synchronization clock for the CDMA signals transmitted by multiple terminal stations in the open wireless channels, eliminating path delay differences from the multiple terminal stations to a relay node or receiving station, and making multi-channel CDMA signals received at the relay node or receiving station clock synchronized and phase aligned. The method can realize the quasi-synchronous reception of multi-channel CDMA signals.

Abstract: An example method for rewarming a cryopreserved material includes identifying a parameter indicating a state of a container enclosing a single-mode electromagnetic field. The method further includes maintaining the single-mode electromagnetic field by adjusting, based on the parameter, a frequency and/or a power of the electromagnetic waves.