Abstract: A luminaire for architectural, industrial and warehouse applications can be assembled using an extruded housing having curved sides connected by a cross member. Windows in the curved sides can allow light to exit toward the sides of the luminaire while most of the light exits through a lens on the bottom. The extrusion can have channels and slots such that optical elements and an LED array can be slid into the housing and retained by end caps. A housing cover can overlie a wireway while being held in place by screws creating a clamping force between the housing cover and fixture brackets retained within the housing. The luminaire can be suspended by the fixture brackets or by elements attached to the fixture brackets.

Abstract: A luminaire for architectural, industrial and warehouse applications can be assembled using an extruded housing having curved sides connected by a cross member. Windows in the curved sides can allow light to exit toward the sides of the luminaire while most of the light exits through a lens on the bottom. The extrusion can have channels and slots such that optical elements and an LED array can be slid into the housing and retained by end caps. A housing cover can overlie a wireway while being held in place by screws creating a clamping force between the housing cover and fixture brackets retained within the housing. The luminaire can be suspended by the fixture brackets or by elements attached to the fixture brackets.

Abstract: A luminaire a small number of carefully designed extrusions is easily manufactured. The housing is formed by joining four pieces having a first extrusion profile. A second extrusion profile is used for the side and end covers. A third profile is used for access covers. The housing frames a lens, such as an acrylic sheet, and long lines of LEDs are positioned to shine directly into the side of the lens. A reflective layer on the lens directs all or some of the LED light out the luminaire's front, perhaps directing some light out the back. Strategically positioned diffusors ensure a pleasing lighting effect. The result is a very thin and light weight luminaire having a large surface area. The luminaire can be suspended by threaded nipples, by cables threaded through holes in the back, or by brackets screwed to threaded inserts.

Abstract: A peptide that binds specifically to neuropilin-1 (NRP1) without binding to neuropilin-2 (NRP2) is provided. A fusion protein, a fusion antibody, small-molecule drug, a nanoparticle, or a liposome, which comprises the peptide, and a pharmaceutical composition for treating or preventing cancer or angiogenesis-related diseases, and a composition for diagnosing cancer or angiogenesis-related diseases are provided. A polynucleotide encoding the peptide that binds specifically to NRP1 and a method for screening the peptide that binds specifically to NRP1 are provided. An antibody heavy-chain constant region Fc-fused peptide binding specifically to NRP1 has the property of binding specifically to NRP1, and thus when it is administered in vivo, it accumulates selectively in tumor tissue, and widens the intercellular space between tumor-associated endothelial cells to promote its extravasation and increases its tumor tissue penetration.

Abstract: Luminaire housings for architectural, industrial and warehouse applications have extrusions with parallel flat sides connected by a cross member. The wireway can be enclosed by the extrusion's roof or by cover segments clamped over an open top extrusion. Wireway openings provide access to the wireway. Nuts slid into T-channels in the roof or cover segments provide for mounting or suspension via wall brackets, cables, and housing brackets. Threaded nipples accessible through the roof or cover segments provide for pendant stem mounting. Continuous run brackets can join housings end to end. Optical elements slid into slots and channels in the housing can be retained by end caps. A housing cover over the wireway can be clamped in place by screws threaded into fixture brackets retained within the housing. The housing grooves in the cover segments can slidably engage the extrusion until the cover segments are clamped in place.

Abstract: A heterodimeric Fc-fused protein and a pharmaceutical composition comprising the heterodimeric Fc-fused protein are disclosed. The heterodimeric Fc-fused protein comprises first and second Fc regions of an immunoglobulin heavy chain constant region (Fc) pair and in which IL-21 is bound to at least one of the N-terminus or the C-terminus of the first Fc region and/or the second Fc region, wherein CH3 domains of the first Fc region and the second Fc region are mutated such that the formation of a heterodimer is promoted. When the heterodimeric Fc-fused protein according to the present invention is used, an in vivo half-life of IL-21 included in the heterodimeric Fc-fused protein may be significantly increased.

Abstract: The present invention relates to an ethylene/alpha-olefin copolymer having excellent processability. The ethylene/alpha-olefin copolymer according to the present invention has excellent processability and is therefore suitable for producing products by an injection molding method.

Abstract: A composition for solar cell electrodes and a solar cell electrode prepared using the same, the composition including a conductive powder; a glass frit; an organic vehicle; a slip agent; and a thixotropic agent, wherein the composition has an angular velocity of 0.1 rad/sec to 80 rad/sec, as measured for tan ? max under conditions of 23 ° C. and 0.1 rad/sec to 1,000 rad/sec.

Abstract: Described herein are antimicrobial compounds identified via a high-throughput inhibitor screen of the in vitro activity of MipZ, which is an ATPase that regulates division site placement in Caulobacter crescentus. The compounds and their analogs are active against bacterial membranes and thus represent a novel class of antimicrobial compounds. The antimicrobial compounds are effective against both actively growing bacterial cells as well as bacterial cells in the stationary phase. The antimicrobial compounds are also effective against bacteria in biofilms.

Abstract: The present invention relates to a heterodimeric Fc-fused protein comprising a first Fc region and a second Fc region of an immunoglobulin Fc pair and a physiologically active protein composed of two or more different subunits, wherein one or more subunits of the physiologically active protein are linked separately to one or more ends of the N-terminus or C-terminus of the first Fc region and/or the second Fc region, and CH3 domains of the first Fc region and the second Fc region are mutated so as to promote the heterodimeric Fc formation. Moreover, the present invention relates to a pharmaceutical composition comprising the heterodimeric Fc-fused protein.

Abstract: The present disclosure provides a folding device for manufacturing an electrode assembly having a structure in which plate type unit cells are wound with a separator film, including: a mandrel configured to rotate and wind a web in which plate type unit cells are arranged on an upper surface of the separator film at predetermined intervals so that the unit cells are sequentially stacked with the separator film interposed therebetween; and a pair of rollers configured to horizontally bend a surplus winding end portion of the separator film, which is formed by arranging a first unit cell at a winding start portion of the web in a state of being spaced apart from a winding end portion of the separator film, in a direction covering an upper surface of the first unit cell, wherein the mandrel includes one or more grippers composed of one or more upper legs configured to fix an upper surface portion of the first unit cell and one or more lower legs configured to fix a lower surface portion of the separator fil

Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.

Abstract: The present invention relates to a method for predicting the physical properties of polymers. More specifically, the present invention relates to a method for predicting long-term stability of polymers using a molecular weight distribution curve.

Abstract: The present invention relates to methods of overcoming the resistance to an EGFR (Epidermal Growth Factor Receptor)-targeting antibody through a peptide that binds specifically to neuropilin-1 (NRP1). Moreover, the present invention relates to a fusion antibody in which a peptide that binds specifically to NRP1 is fused to an EGFR-targeting antibody, and to a composition of overcoming the resistance to an EGFR-targeting antibody alone by co-administration of the EGFR-targeting antibody and an NRP1-binding peptide-fused Fc. In addition, the fusion antibody according to the present invention, in which the NRP1-specific binding peptide is fused to an EGFR-targeting antibody, overcomes the resistance to the EGFR-targeting antibody alone in pancreatic cancer. Furthermore, the fusion antibody, in which the NRP1-specific binding peptide is fused to the EGFR-targeting antibody, also overcomes resistance to the EGFR-targeting antibody alone even in lung cancer.

Abstract: The present invention relates to a supported hybrid catalyst system for ethylene slurry polymerization and a method for preparing ethylene polymer therewith. The supported hybrid catalyst system according to the present invention may exhibit high activity during ethylene slurry polymerization, and enables preparation of an ethylene polymer having a narrow molecular weight distribution but excellent processability.

Abstract: A composition for solar cell electrodes includes a conductive powder, a glass frit, and an organic vehicle. The glass frit contains about 20 mol % to about 40 mol % of an alkali metal, about 20 mol % to about 30 mol % of zinc (Zn), and about 7 mol % to about 20 mol % of magnesium (Mg) in terms of oxide content.

Abstract: Provided is a method for preparing a novel benzocoumarin-based two-photon absorbing fluorescent dye, such as a pyridinium-benzocoumarin (Py+BC) derivative compound and its precursor compound (pyridyl-benzocoumarin, PyBC), an aryl-benzocoumarin (ArBC) derivative compound, a benzothiazolyl-benzocoumarin (BtBC) derivative compound or a keto-benzocoumarin (KetoBC) derivative compound. The Py+BC derivative compound of the present invention is a two-photon absorbing near-infrared fluorescent dye, which may minimize interference of autofluorescence compared to conventional two-photon absorbing fluorescent dyes such as acedan and naphthalimide, thereby obtaining a high-definition image, and therefore is expected to be effectively used in imaging studies. In addition, when the two-photon absorbing near-infrared fluorescent dye of the present invention is used, it is expected to be suitable for high resolution imaging of deep tissue.

Abstract: Described herein is a descriptive framework to facilitate error detection in recognition data. In accordance with one aspect of the framework, at least one erroneous record is detected in a first set of recognition data. The framework may determine a correction of a first recognized identifier in the erroneous record by searching a second set of recognition data for a matching record with a second recognized identifier substantially similar to the first recognized identifier. A report may then be generated to present the detected erroneous record and the determined correction.

Abstract: This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin ? complexed with heparin and/or heparin-like structure (AT?H). These AT?H binding proteins can block the anti-coagulant activity of AT? to induce coagulation. Therapeutic uses of these antibodies and binders are described herein as are methods of panning and screening specific antibodies.

Abstract: Provided is a composition for preventing, improving or treating obesity, which includes a Platycodon grandiflorum extract as an active ingredient and a method for preparing the extract with an improved anti-obesity effect. The extract shows an effect of inhibiting increases in body weight and fat mass caused by a high-fat diet for normalization, an increase in fasting blood glucose and a decrease in energy expenditure in a diet-induced obesity mouse model. Further, compared to an extract prepared by a conventional extraction method, the Platycodon grandiflorum extract shows a more excellent effect of inhibiting increases in body weight and fat mass, fasting blood glucose, and blood lipid and adipokine contents in experiments, resulting in an excellent anti-obesity effect. Therefore, the Platycodon grandiflorum extract prepared is expected to be useful for preventing obesity and treating obesity-related complications that can be caused by an increase in fat mass as well as obesity.