Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: A manufacturing method of an attraction plate for electromagnetic door locks has an attraction plate positioned on a mounted body with a positioning hole at the center thereof. The attraction plate further has an arch portion at the center thereof which is reversely proportional to a thickness thereof and the thickness thereof is pre-determined for manufacturing a different height of the arch portion thereof for better effects. With an internal stress from the curved design, a tensile value of a door lock is increased for better operation of a door lock.

Abstract: The present invention is a battery rescue activating reset device, used for powering a preset battery, the reset device including: a power supplier, a control circuit, an anode connection line, a cathode connection line and a connection line used for resetting. The control circuit includes an electric switch used for switch the power supplier to power the battery, when the anode connection line is connected to the anode end of the battery, or the cathode connection line is connected to the cathode end of the battery, then the connection line used for resetting is connected to both the anode end or the cathode end of the battery, and when the anode connection line is not connected to the anode end of the battery, or the cathode connection line is not connected to the cathode end of the battery, then meanwhile the connection line used for resetting is not connected to the anode end or the cathode end of the battery, making the electric switch closed.

Abstract: A spectro-colorimeter system for imaging pipeline is provided, the system including a camera system; a spectrometer system; and a controller coupling the camera system and the spectrometer system. In some embodiments the camera system is configured to provide a color image with the first portion of the incident light. Also, in some embodiments the spectrometer system is configured to provide a tristimulus signal from the second portion of the incident light. Furthermore, in some embodiments the controller is configured to correct the color image from the camera system using the tristimulus signal from the spectrometer. An imaging pipeline method for using a system as above is also provided. Further, a method for color selection in an imaging pipeline calibration is provided.

Abstract: A display device includes a substrate, a light source, a reflecting structure, and an optical film set. The light source and the reflecting structure are disposed on the substrate. The reflecting structure has an opening, and the light source is correspondingly disposed in the opening. The optical film set is disposed on the reflecting structure, and at least part of the optical film set overlaps with the light source. The optical film set includes a semi-transmissive film disposed on the reflecting structure, a diffuser film disposed on the semi-transmissive film, and a conversion film disposed on the diffuser film.

Abstract: Embodiment described herein provide a thermal treatment process following a high-pressure anneal process to keep hydrogen at an interface between a channel region and a gate dielectric layer in a field effect transistor while removing hydrogen from the bulk portion of the gate dielectric layer. The thermal treatment process can reduce the amount of threshold voltage shift caused by a high-pressure anneal. The high-pressure anneal and the thermal treatment process may be performed any time after formation of the gate dielectric layer, thus, causing no disruption to the existing process flow.

Abstract: A method of forming a semiconductor device includes depositing a flowable dielectric layer on a substrate and annealing the flowable dielectric layer. The method further includes performing a high temperature (HT) doping process on the flowable dielectric layer. The HT doping process may include implanting dopant ions into the flowable dielectric layer and heating the substrate during the implanting of the dopant ions. The heating of the substrate may include heating a substrate holder upon which the substrate is disposed and maintaining the substrate at a temperature above 100° C. An example benefit reduced the wet etch rate (WER) of the flowable dielectric layer.

Abstract: The present invention discloses an encapsulation layer structure including a first organic layer, an inorganic thin film, and a second organic layer. The first organic layer has a bottom surface and a first wavy surface opposite to the bottom surface. The first wavy surface has a plurality of peak portions and a plurality of valley portions, and the peak portions and valley portions are alternately arranged with each other. The inorganic thin film is conformally disposed on the first wavy surface of the first organic layer, and the inorganic thin film has a second wavy surface opposite to the first wavy surface. The second organic layer is over the second wavy surface of the inorganic thin film. This encapsulation layer structure may prevent the penetration of oxygen and moisture effectively.

Abstract: Methods and systems for audio content production are provided whereby expressive speech is generated via acoustic elements extracted from human input. One of the inputs to the system is a human designating an intonation to be applied onto text-to-speech (TTS) generated synthetic speech. The human intonation includes the pitch contour and other acoustic features extracted from the speech. The system is designed to be used for, and is capable of speech generation, speech analysis, speech transformation, and speech re-synthesis at the acoustic level.

Abstract: Implementations include systems and methods for scoring candidates for set recommendation problems. An example method includes repeating, for each code in code arrays for items in a set of items, determining a most common value for the code. In some implementations, the method includes determining that the most common value occurs with a frequency that meets an occurrence threshold and adding the code and the most common value to set-inclusion criteria. In other implementations, the method includes determining a value for the code from a code array for a seed item and adding the code and the most common value to set-inclusion criteria when the value for the code from the code array for the seed item matches the most common value. The method may also include evaluating a similarity with a candidate item based on the set-inclusion criteria and basing a recommendation regarding the candidate item on the similarity.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: Disclosed is a salt of a quinoline derivative, polymorphic forms thereof, preparation methods thereof, a composition, and applications. The SPH1772 ditartrate or crystal form A thereof expresses the following excellent properties: high stability, great bioavailability, excellent pharmacokinetic properties, and better in vivo efficacy than SPH1772 free base.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: An electronic computing device, a method for adjusting the trigger mechanism of a garbage collection function, and a non-transitory computer readable storage medium thereof are provided. A storage unit of the electronic computing device stores a whitelist. The whitelist records a plurality of data sets, wherein each of the data sets has a name of an application and an offset value of the application. A processor of the electronic computing device executes a system program. The system program loads the whitelist into a memory during a initialization procedure. The system program detects that a specific application is triggered and retrieves the offset value of the specific application from the whitelist in the memory according to the name of the specific application. The system program forks a process to the specific application and updates a threshold of a garbage collection function according to the offset value.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are liver X receptor modulators, and which are useful in the treatment of diseases and disorders associated with the liver X receptor. Also provided are the compounds of Formula (I) and pharmaceutical compositions thereof for treating atherosclerosis, cardiovascular disease, Alzheimer's disease, dermatitis, dyslipidemia, cancer and other diseases or disorders.

Abstract: Layering of initially mixed granular dissimilar material components deposited by surface flow is realized by varying the relative angle of the flowing layer periodically with respect to the bulk of the pile formed. Layer thickness and extent can be controlled by varying the timing and extent of the surface variations. Variation in surface flow rates may be realized by varying the feed rate from an inlet to a collection base at a fixed feed location, varying the feed location relative to the collection base, tilting the collection base that is supporting the material, and reducing the pile repose angle using vibration or fluid flow through the base.

Abstract: A catalog attribute and catalog program code containing the catalog attribute can be identified in a document object model (DOM) for a web page. The catalog program code can define a structure of a catalog for the web page. Responsive to identifying the catalog program code, the catalog for the web page can be generated by processing the catalog program code. The catalog can include a plurality of user selectable catalog items. At least a first portion of the catalog items can be configured to, in response to being selected by the user, navigate the user to a respective content of the web page. The catalog can be presented in a user interface.

Abstract: A method for fabricating semiconductor device includes the steps of: forming a fin-shaped structure on a substrate; forming a shallow trench isolation (STI) around the fin-shaped structure; forming a liner on the fin-shaped structure; and removing the liner and part of the fin-shaped structure so that a sidewall of the fin-shaped structure comprises a curve. Moreover, the method includes forming an epitaxial layer around the sidewall of the fin-shaped structure while a top surface of the fin-shaped structure is exposed.

Abstract: A semiconductor device preferably includes a substrate, a fin-shaped structure on the substrate, a buffer layer on the fin-shaped structure, and an epitaxial layer on the buffer layer. Preferably, the buffer layer is made of silicon germanium and including three or more than three elements. The buffer layer also includes dopants selected from the group consisting of P, As, Sb, Bi, C, and F.