Patents by Inventor Yi-Hsing Chen

Yi-Hsing Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240216496
    Abstract: A recombinant lactic acid bacterium and a method thereof for simultaneous treatment and/or prevention of dust mite and cockroach allergies. The recombinant lactic acid bacterium has a gene fragment with nucleotide coded as SEQ ID No: 1 to be capable of expressing the D2P2 protein with amino acid sequence of SEQ ID No: 2. Therefore, by administering an effective amount of the recombinant lactic acid bacterium to an individual is capable of effectively causing the individual's body to produce antibodies against dust mite and/or cockroach allergens, thereby achieving an efficacy of preventing and/or treating an allergic disease caused by dust mite and/or cockroach allergens.
    Type: Application
    Filed: June 7, 2023
    Publication date: July 4, 2024
    Inventors: Mey Fann LEE, Yi-Hsing CHEN
  • Patent number: 11889835
    Abstract: The present invention relates to a plant growth regulator of elevating anti-stress ability and use thereof. The plant growth regulator, which is consisted of Lactobacillus fermenting culture solution, has excellent thermostability and safety without any side effect, significantly elevating ability against biotic and abiotic stresses. Therefore, the Lactobacillus fermenting culture solution can be applied as the plant growth regulator or a use in preparation of a composition for elevating anti-stress ability of a plant.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: February 6, 2024
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Tsuei-Yin Huang, Hsiang-En Huang, Yu-Jen Hsu
  • Patent number: 11541084
    Abstract: A composition having Lactobacillus Plantarum strain GMNL-662 for promoting bone regrowth is provided. The Lactobacillus Plantarum strain GMNL-662 has an ability to promote the expression of osteogenic genes, inhibit the expression of osteoclast related genes, and promote the expression of osteogenesis-related cytokine TGF-?, so that the bone loss is improved.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: January 3, 2023
    Assignee: .GENMONT BIOTECH INC
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Chi Chien Lin
  • Patent number: 11318176
    Abstract: The present invention relates to a topical composition of facilitating wound healing and reducing scars, which includes an inactivated culture of Lactobacillus species as an effective ingredient and can significantly facilitate wound healing as well as reducing scars, thereby can be applied to a method of facilitating wound healing and reducing scars.
    Type: Grant
    Filed: August 13, 2019
    Date of Patent: May 3, 2022
    Assignee: GenMont Biotech Incorporation
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Wei Chang, Chia-Hsuan Chou
  • Publication number: 20220105141
    Abstract: Present invention discloses a Lactobacillus composition comprising Lactobacillus reuteri GMNL-263 which is a strain of heat-killed dead bacteria and has the effect of lowering blood pressure by inhibition of proinflammatory cytokine IL-1? and enhancement the growth of Bifidobacterium, and said Lactobacillus composition is a pharmaceutical composition, nutritional supplement, health food or a combination thereof.
    Type: Application
    Filed: December 15, 2021
    Publication date: April 7, 2022
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai
  • Patent number: 11007137
    Abstract: The present invention provides a use for probiotic preparing skin care composition, wherein the probiotic comprises Lactobacillus plantarum (GMNL-6) with preservation number of BCRC 910777 or CCTCC M 2017765. The composition may be externally-coating drug, pharmaceuticals for external use, care products for external use or cosmetics, and may achieve the effects of improving the skin conditions or aesthetic appearance by promoting secretion of collagen or expression of ceramide synthase.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: May 18, 2021
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Ying-Ju Chiang
  • Publication number: 20200368298
    Abstract: A composition having Lactobacillus Plantarum strain GMNL-662 for promoting bone regrowth is provided. The Lactobacillus Plantarum strain GMNL-662 has an ability to promote the expression of osteogenic genes, inhibit the expression of osteoclast related genes, and promote the expression of osteogenesis-related cytokine TGF-?, so that the bone loss is improved.
    Type: Application
    Filed: August 3, 2020
    Publication date: November 26, 2020
    Inventors: Yi-Hsing CHEN, Wan-Hua Tsai, Chia-Hsuan Chou, Chi Chien Lin
  • Patent number: 10646522
    Abstract: The present invention is related to a Lactobacillus strain, composition and use thereof for treating autoimmune disease and related complications. The composition comprises at least one isolate of Lactobacillus paracasei strain GMNL-32, L. reuteri strain GMNL-89 or L. reuteri strain GMNL-263, and a pharmaceutical carrier, for treating syndromes and related complications of the autoimmune diseases.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: May 12, 2020
    Assignee: GenMont Biotech Incorporation
    Inventors: Chih-Yang Huang, Wei-Wen Kuo, Bor-Show Tzang, Yi-Hsing Chen
  • Patent number: 10639336
    Abstract: The present invention provides a composition for preventing stroke and ameliorating the severity of stroke and comprises an effective dose of Lactobacillus reuteri GMNL-89 and Lactobacillus paracasei GMNL-133; the accession number of Lactobacillus reuteri GMNL-89 is CCTCC M207154 and the accession number of Lactobacillus paracasei GMNL-133 is CCTCC M2011331. The composition can be taken as a dietary supplement and be given continuously after a stroke, and said composition has the effects of ameliorating cerebral infarction, motor function, and intestinal microbiota after a stroke.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: May 5, 2020
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Shiang-Suo Huang, Yi-Hsin Wang
  • Patent number: 10638784
    Abstract: The present invention provides a pharmaceutical composition and a food product for inhibiting gastritis induced by gastric Helicobacter pylori, comprising Lactobacillus selected from a group composed of Lactobacillus rhamnosus GM-020 (also known as GMNL-74) with deposited number CCTCC M203098; Lactobacillus acidophilus GMNL-185 with deposited number CCTCC M2017764; and Lactobacillus plantarum GMNL-662 with deposited number CCTCC M2016571; and any two of the above bacteria.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: May 5, 2020
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Ya-Hui Chen, Chih-Ho Lai, Yu-Hsin Lin
  • Patent number: 10632160
    Abstract: The present invention relates to a probiotic composition for preventing, improving or alleviating pancreatic cancer and a method for preventing, improving or alleviating the pancreatic cancer and its complications using the probiotic composition. The probiotic composition, which is consisted of specific strains and specific ratio of Lactobacillus paracasei to Lactobacillus reuteri, can significantly improve or alleviate various symptomatic indicators and severity of pancreatic cancer, thereby being applied on a method for preventing, improving or alleviating the pancreatic cancer and its complications using an oral composition including the Lactobacillus strains.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: April 28, 2020
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh, Ming-Shiou Jan, Yen-Wan Hsiao, Li-Jin Hsu, Junko Sugawara
  • Publication number: 20200077692
    Abstract: The present invention provides a pharmaceutical composition and a food product for inhibiting gastritis induced by gastric Helicobacter pylori, comprising Lactobacillus selected from a group composed of Lactobacillus rhamnosus GM-020 (also known as GMNL-74) with deposited number CCTCC M203098; Lactobacillus acidophilus GMNL-185 with deposited number CCTCC M2017764; and Lactobacillus plantarum GMNL-662 with deposited number CCTCC M2016571; and any two of the above bacteria.
    Type: Application
    Filed: September 12, 2018
    Publication date: March 12, 2020
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Ya-Hui Chen, Chih-Ho Lai, Yu-Hsin Lin
  • Publication number: 20200054694
    Abstract: The present invention relates to a topical composition of facilitating wound healing and reducing scars, which includes an inactivated culture of Lactobacillus species as an effective ingredient and can significantly facilitate wound healing as well as reducing scars, thereby can be applied to a method of facilitating wound healing and reducing scars.
    Type: Application
    Filed: August 13, 2019
    Publication date: February 20, 2020
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Wei Chang, Chia-Hsuan Chou
  • Patent number: 10555979
    Abstract: Use of Lactobacillus paracasei for preparing for a combination for alleviating axillary osmidrosis is provided in the present invention, wherein Lactobacillus paracasei refers in particular to Lactobacillus paracasei GMNL-653, featuring abilities of aggregating and inhibiting pathogens of axillary osmidrosis for alleviation of armpit odors and presented as a topical medication or a combination of cosmetics in which fragrance is added.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: February 11, 2020
    Assignee: GENMONT BIOTECH INCORPORATION
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Tsuei-Yin Huang
  • Publication number: 20190388484
    Abstract: Present invention discloses a Lactobacillus composition comprising Lactobacillus reuteri GMNL-263 which is a strain of heat-killed dead bacteria and has the effect of lowering blood pressure by inhibition of proinflammatory cytokine IL-1? and enhancement the growth of Bifidobacterium, and said Lactobacillus composition is a pharmaceutical composition, nutritional supplement, health food or a combination thereof.
    Type: Application
    Filed: June 26, 2018
    Publication date: December 26, 2019
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai
  • Publication number: 20190381118
    Abstract: Use of Lactobacillus paracasei for preparing for a combination for alleviating axillary osmidrosis is provided in the present invention, wherein Lactobacillus paracasei refers in particular to Lactobacillus paracasei GMNL-653, featuring abilities of aggregating and inhibiting pathogens of axillary osmidrosis for alleviation of armpit odors and presented as a topical medication or a combination of cosmetics in which fragrance is added.
    Type: Application
    Filed: October 4, 2018
    Publication date: December 19, 2019
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Tsuei-Yin Huang
  • Patent number: 10456430
    Abstract: A composition is used for prevention or treatment of bacterial vaginosis (BV) and regulation of vaginal immunity and said composition with effective amount is selected from the groups comprising Lactobacillus rhamnosus GMNL-680 and Lactobacillus plantarum GMNL-682; the composition of the present invention is used to prevent and treat bacterial vaginosis by inhibition of the growth of pathogens and regulation of the expression of immunoregulators and is prepared in the forms of pharmaceutical compositions, food or other combinations thereof.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: October 29, 2019
    Assignee: Genmont Biotech Incorporation
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh
  • Patent number: 10456428
    Abstract: A method and a composition having the Lactobacillus paracasei strain GMNL-653 for treating psoriasis is provided. The Lactobacillus paracasei strain GMNL-653 has anti-inflammation properties, and inhibits the secretion of cytokine IL-6 and IL-17, so that the psoriasis symptoms caused by over-inflammation are improved/relieved.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: October 29, 2019
    Assignee: GENMONT BIOTECH INC.
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Chia-Hsuan Chou, Pei-Jane Tsai, Tsuei Yin Huang
  • Publication number: 20190320659
    Abstract: The present invention relates to a plant growth regulator of elevating anti-stress ability and use thereof. The plant growth regulator, which is consisted of Lactobacillus fermenting culture solution, has excellent thermostability and safety without any side effect, significantly elevating ability against biotic and abiotic stresses. Therefore, the Lactobacillus fermenting culture solution can be applied as the plant growth regulator or a use in preparation of a composition for elevating anti-stress ability of a plant.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 24, 2019
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Tsuei-Yin Huang, Hsiang-En Huang, Yu-Jen Hsu
  • Publication number: 20190290707
    Abstract: The present invention relates to a probiotic composition for preventing, improving or alleviating pancreatic cancer and a method for preventing, improving or alleviating the pancreatic cancer and its complications using the probiotic composition. The probiotic composition, which is consisted of specific strains and specific ratio of Lactobacillus paracasei to Lactobacillus reuteri, can significantly improve or alleviate various symptomatic indicators and severity of pancreatic cancer, thereby being applied on a method for preventing, improving or alleviating the pancreatic cancer and its complications using an oral composition including the Lactobacillus strains.
    Type: Application
    Filed: March 22, 2019
    Publication date: September 26, 2019
    Inventors: Yi-Hsing Chen, Wan-Hua Tsai, Wen-Ling Yeh, Ming-Shiou Jan, Yen-Wan Hsiao, Li-Jin Hsu, Junko Sugawara