Patents by Inventor Yi Xia

Yi Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210137938
    Abstract: The present invention relates to the treatment of a tumor selected from the group consisting of pancreatic cancer, liver cancer, melanoma, colon cancer, glioblastoma, osteosarcoma, prostate cancer and breast cancer, more particularly pancreatic cancer. The inventors found a novel family compounds of formula (I) able to treat a variety of cancers by inhibiting NUPR1, a stress-inducible 82-amino-acid-long, intrinsically disordered member of the AT-hook family of chromatin proteins. Thus, the present invention relates to a compound of formula (I) for its use in the treatment of a tumor selected from the group consisting of pancreatic cancer, liver cancer, melanoma, colon cancer, glioblastoma, osteosarcoma, prostate cancer and breast cancer. In particular, the inventors tested compounds of formula (I) on four well characterized primary pancreatic cancer-derived cells 02.
    Type: Application
    Filed: May 31, 2019
    Publication date: May 13, 2021
    Inventors: Olga ABIAN FRANCO, Patricia SANTOFIMIA, Yi XIA, Jose Luis NEIRA, Bruno RIZZUTI, Adrian VELAZQUEZ CAMPOY, Ling PENG, Juan IOVANNA
  • Publication number: 20210120703
    Abstract: An apparatus is described. The apparatus includes a liquid cooling system having multiple heat-exchangers and multiple valves. The multiple valves are to enable/disable participation of individual ones of the heat-exchangers within the liquid cooling system. The apparatus includes an information keeping device to store information that correlates a number of the multiple heat exchangers to be enabled to realize one or more semiconductor chips' target temperature for a power consumption of the one or more semiconductor chips for a plurality of combinations of target temperature and power consumption.
    Type: Application
    Filed: December 26, 2020
    Publication date: April 22, 2021
    Inventors: Prabhakar SUBRAHMANYAM, Arun KRISHNAMOORTHY, Victor POLYANKO, Ying-Feng PANG, Yi XIA, Pooya TADAYON, Muhammad AHMAD, Rahima K. MOHAMMED
  • Publication number: 20210116391
    Abstract: An apparatus is described. The apparatus includes an electronic system having a printed circuit board with electronic components mounted thereon. At least some of the electronic components are coupled to components of a liquid cooling system. The electronic system has a light source and a photosensitive element. The light source is to illuminate an illuminated region of the printed circuit board and/or at least one of the electronic components. The photosensitive element is to detect a change in reflection from the illuminated region in response to the presence of coolant that has leaked from the liquid cooling system within the illuminated region.
    Type: Application
    Filed: December 23, 2020
    Publication date: April 22, 2021
    Inventors: Prabhakar SUBRAHMANYAM, Ying-Feng PANG, Yi XIA, Mark BIANCO, Victor POLYANKO
  • Patent number: 10919916
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: February 16, 2021
    Assignee: Bill & Melinda Gates Foundation
    Inventors: Xianfeng Li, Christopher S Lunde, Robert T Jacobs, Vincent S Hernandez, Yi Xia, Jacob J Plattner, Kathy Jingyuan Cao, Yong-Kang Zhang, Matthew Perry
  • Patent number: 10904137
    Abstract: Embodiments of the invention relate to virtual link aggregation. One embodiment includes forming one or more virtual links using physical links connecting a first networking element, a second networking element and a third networking element. A first trigger status indication is used for blocking network traffic for avoiding traffic loops occurring over the one or more virtual links.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: January 26, 2021
    Assignee: International Business Machines Corporation
    Inventors: Tamanna Z. Sait, Venkatesan Selvaraj, Shoou J. Yiu, Yi Xia
  • Publication number: 20200323051
    Abstract: The present invention provides a microwave-based high-throughput material processing device with a concentric rotary chassis. The device includes a microwave source generator, a microwave reaction chamber, and a temperature acquisition device. The microwave reaction chamber is provided with a rotary table, a thermal insulation barrel and a crucible die. The thermal insulation barrel is disposed on the rotary table, and the crucible die is disposed in the thermal insulation barrel. The crucible die is provided with a plurality of first grooves, and the first grooves are evenly distributed on a first circumference. A plurality of first fixing holes are disposed on a top of the thermal insulation barrel, and the first fixing holes are disposed corresponding to the first grooves. A first acquisition hole is disposed on the top of the microwave reaction chamber, and the first acquisition hole is located right above the first circumference.
    Type: Application
    Filed: April 3, 2020
    Publication date: October 8, 2020
    Applicant: Kunming University of Science and Technology
    Inventors: Lei Xu, Jinhui Peng, Shenghui Guo, Libo Zhang, Zhaohui Han, Yi Xia, Shaohua Ju, Shanju Zheng, Shiwei Li, Zemin Wang, Zhang Xu
  • Patent number: 10768085
    Abstract: The present disclosure relates to, inter alia, systems and methods for measuring contact-line mobility of a liquid on a solid substrate. The system includes a motion-generation component, a motion-measurement component, and a computer component. The motion-generation component can include an actuator and a controller, the actuator being adapted to mount a solid substrate and effective to impart periodic forcing to the solid substrate when a test droplet of the liquid is deposited thereon, and the controller being adapted to tune frequency and amplitude of the forcing to induce measurable contact-line displacement of the test droplet on the solid substrate. The motion-measurement component includes an image acquisition device adapted for capturing images of the test droplet.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: September 8, 2020
    Assignee: CORNELL UNIVERSITY
    Inventors: Paul H. Steen, Yi Xia
  • Patent number: 10740543
    Abstract: A plurality of objects associated with respective footnote reference information within a document are generated. An overflow object associated with overflow footnote reference information corresponding to a previous footnote marker appearing on a previous page is invoked to lay out the overflow footnote reference information, generating overflow layout data. A current page object associated with current page footnote reference information that corresponds to a current page footnote marker appearing on the page is invoked to lay out the current page footnote reference information, generating current page footnote reference information layout data, if an available footnote height is sufficient to lay out the current page footnote reference information. The page is displayed based on the overflow layout data and the current page footnote reference information layout data.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: August 11, 2020
    Assignee: GOOGLE LLC
    Inventors: Luiz Do Amaral De Franca Pereira Filho, Edgard Lindner, Venkat Ganesan, Kevin Markman, Lily Shu-Yi Xia
  • Publication number: 20200247827
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: April 3, 2020
    Publication date: August 6, 2020
    Applicant: Bill & Melinda Gates Foundation
    Inventors: Xianfeng LI, Christopher S LUNDE, Robert T JACOBS, Vincent S HERNANDEZ, Yi XIA, Jacob J PLATTNER, Kathy Jingyuan CAO, Yong-Kang ZHANG, Matthew PERRY
  • Patent number: 10611780
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: April 7, 2020
    Assignee: Bill and Melinda Gates Foundation
    Inventors: Xianfeng Li, Christopher S. Lunde, Robert T. Jacobs, Vincent S. Hernandez, Yi Xia, Jacob J. Plattner, Kathy Jingyuan Cao, Yong-Kang Zhang, Matthew Perry
  • Publication number: 20200053001
    Abstract: Embodiments of the invention relate to virtual link aggregation. One embodiment includes forming one or more virtual links using physical links connecting a first networking element, a second networking element and a third networking element. A first trigger status indication is used for blocking network traffic for avoiding traffic loops occurring over the one or more virtual links.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 13, 2020
    Inventors: Tamanna Z. Sait, Venkatesan Selvaraj, Shoou J. Yiu, Yi Xia
  • Patent number: 10511519
    Abstract: Embodiments of the invention relate to virtual link aggregation. One embodiment includes forming one or more virtual links using physical links connecting a first networking element, a second networking element and a third networking element. A first trigger status indication is used for blocking network traffic for avoiding traffic loops occurring over the one or more virtual links.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: December 17, 2019
    Assignee: International Business Machines Corporation
    Inventors: Tamanna Z. Sait, Venkatesan Selvaraj, Shoou J. Yiu, Yi Xia
  • Publication number: 20190316434
    Abstract: A downhole tool having a mandrel, and a bottom slip disposed around the mandrel. The bottom slip includes a circular body having a one-piece configuration characterized by a plurality of slip segments by at least partial material connectivity therearound. The bottom slip is made of a filament wound composite material, which means the bottom slip has a plurality of layers joined by respective interface layers. An outer slip surface of at least one of the plurality of slip segments is defined in cross-section by a plane P that intersects a longitudinal axis of the downhole tool at an angle a1 in a range of 10 degrees to 20 degrees when the bottom slip is in an unset position.
    Type: Application
    Filed: August 21, 2018
    Publication date: October 17, 2019
    Inventors: Evan Lloyd Davies, Yi Xia, Luis Miguel Avila, David Hughes, Gabriel Slup, Ashton E. Diaz
  • Publication number: 20190114295
    Abstract: Techniques for improving complex database queries are provided. A determination is made whether to adopt a static or dynamic query execution plan for a received database query based on metrics. When a dynamic query execution plan is adopted, the database query is separated into query fragments. A plan fragment is generated for each query fragment and executed to generate feedback for the plan fragment. The feedback from the execution of each plan fragment is used to initiate query rewrite rules to simplify the corresponding query fragments. The rewritten query fragments are combined to generate the dynamic query plan.
    Type: Application
    Filed: December 12, 2018
    Publication date: April 18, 2019
    Applicant: Teradata US, Inc.
    Inventors: Bin Cao, Yi Xia, Sanjib Mishra, Rama Krishna Korlapati, Tri Minh Tran, Mohammed Al-Kateb, Paul Laurence Sinclair, Chengyang Zhang
  • Publication number: 20190077814
    Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.
    Type: Application
    Filed: February 27, 2017
    Publication date: March 14, 2019
    Inventors: Xianfeng Li, Christopher S. Lunde, Robert T. Jacobs, Vincent S. Hernandez, Yi Xia, Jacob J. Plattner, Kathy Jingyuan Cao, Yong-Kang Zhang, Matthew Perry
  • Publication number: 20190025177
    Abstract: The present disclosure relates to, inter alia, systems and methods for measuring contact-line mobility of a liquid on a solid substrate. The system includes a motion-generation component, a motion-measurement component, and a computer component. The motion-generation component can include an actuator and a controller, the actuator being adapted to mount a solid substrate and effective to impart periodic forcing to the solid substrate when a test droplet of the liquid is deposited thereon, and the controller being adapted to tune frequency and amplitude of the forcing to induce measurable contact-line displacement of the test droplet on the solid substrate. The motion-measurement component includes an image acquisition device adapted for capturing images of the test droplet.
    Type: Application
    Filed: July 18, 2018
    Publication date: January 24, 2019
    Applicant: CORNELL UNIVERSITY
    Inventors: Paul H. STEEN, Yi XIA
  • Publication number: 20180292391
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: February 20, 2018
    Publication date: October 11, 2018
    Inventors: Tim BEAUMONT, Mark Jeroen KWAKKENBOS, Eric J. BROWN, John Hiroshi MORISAKI, Wouter L.W. HAZENBOS, Sanjeev MARIATHASAN, Kimberly KAJIHARA, Yi XIA
  • Publication number: 20180125995
    Abstract: The invention provides rF1 antibody antibiotic conjugates and methods of using same.
    Type: Application
    Filed: June 2, 2017
    Publication date: May 10, 2018
    Applicant: Genentech, Inc.
    Inventors: Eric Brown, Wouter Hazenbos, Isidro Hotzel, Kimberly Kajihara, Sophie M. Lehar, Sanjeev Mariathasan, Thomas Pillow, Leanna Staben, Vishal Verma, Binqing Wei, Yi Xia, Min Xu
  • Patent number: D877216
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: March 3, 2020
    Assignee: The WellBoss Company, LLC
    Inventors: Evan Lloyd Davies, Yi Xia, Luis Miguel Avila, David Hughes, Gabriel Slup
  • Patent number: D877217
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: March 3, 2020
    Assignee: The WellBoss Company, LLC
    Inventors: Evan Lloyd Davies, Yi Xia, Luis Miguel Avila, David Hughes, Gabriel Slup