Patents by Inventor Yi Xia

Yi Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gram-positive bacteria specific binding compounds
    Patent number: 8617556
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: December 31, 2013
    Assignees: Genentech, Inc., AIMM Therapeutics B.V.
    Inventors: Tim Beaumont, Mark Jeroen Kwakkenbos, Eric J. Brown, John Hiroshi Morisaki, Wouter L. W. Hazenbos, Sanjeev Mariathasan, Kimberly Kajihara, Yi Xia
  • Triazole derivatives, their preparation and their application in therapeutics
    Patent number: 8563526
    Abstract: The present invention relates to novel compounds of formula (A): in the form of a free base or of an addition salt with an acid. The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: October 22, 2013
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Ling Peng, Palma Rocchi, Juan Iovanna, Yi Xia, Fanqi Qu, Jinqiao Wan, Yang Liu, Menghua Wang
  • GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS
    Publication number: 20130261293
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: March 5, 2013
    Publication date: October 3, 2013
    Applicant: GENENTECH, INC.
    Inventors: Tim BEAUMONT, Mark Jeroen KWAKKENBOS, Eric J. BROWN, John Hiroshi MORISAKI, Wouter L.W. HAZENBOS, Sanjeev MARIATHASAN, Kimberly KAJIHARA, Yi XIA
  • GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS
    Publication number: 20130253175
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: March 5, 2013
    Publication date: September 26, 2013
    Applicant: GENENTECH, INC.
    Inventors: Tim BEAUMONT, Mark Jeroen KWAKKENBOS, Eric J. BROWN, John Hiroshi MORISAKI, Wouter L.W. HAZENBOS, Sanjeev MARIATHASAN, Kimberly KAJIHARA, Yi XIA
  • Boron-containing small molecules as anti-inflammatory agents
    Patent number: 8461135
    Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.
    Type: Grant
    Filed: September 19, 2011
    Date of Patent: June 11, 2013
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Yong-Kang Zhang, Charles Z. Ding, Jacob J. Plattner, Kirk R. Maples, Yvonne Freund, Virginia Sanders, Yi Xia, Stephen J. Baker, James A. Nieman, Xiaosong Lu, Marcelo Sales, Rashmi Sharma, Rajeshwar Singh, Robert T. Jacobs, Daitao Chen, Michael Richard Kevin Alley
  • Trisubstituted boron-containing molecules
    Patent number: 8343944
    Abstract: This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 1, 2013
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Yi Xia, Michael Richard Kevin Alley, Yasheen Zhou, Rajeshwar Singh, Charles Ding, Kathy Cao, Jacob J. Plattner, Ligong Ou, Guofeng Jia, Neerja Saraswat, Sreekanth Ramachandran, Ding Zhou
  • Method for repairing motherboard
    Patent number: 8250722
    Abstract: A method is utilized for repairing a motherboard with a defective dual inline memory module (DIMM) socket mounted thereon be surface mounted technology (SMT). The method includes following steps. Repair tools including a ball grid array (BGA) rework device, a steel bar, a nozzle, and a steel sheet are provided. The BGA rework device, the nozzle are align with the defective DIMM on the motherboard for heating up solder balls between the defective DIMM and the motherboard until the solder balls are melted. The defective DIMM is removed from the motherboard. The steel bar is installed on a replacement DIMM to detect a planarity of a bottom face of the replacement DIMM. The replacement DIMM is mounted on the motherboard to replace the defective DIMM if the replacement DIMM is qualified.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: August 28, 2012
    Assignees: Hong Fu Jin Precision Industry (ShenZhen) Co., Ltd., Hon Hai Precision Industry Co., Ltd.
    Inventor: Yi Xia
  • BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS
    Publication number: 20120214765
    Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.
    Type: Application
    Filed: September 19, 2011
    Publication date: August 23, 2012
    Applicant: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Yong-Kang Zhang, Charles Z. Ding, Jacob J. Plattner, Kirk R. Maples, Yvonne Freund, Virginia Sanders, Yi Xia, Stephen J. Baker, James A. Nieman, Xiaosong Lu, Marcelo Sales, Rashmi Sharma, Rajeshwar Singh, Robert T. Jacobs, Daitao Chen, Michael Richard Kevin Alley
  • GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS
    Publication number: 20120157665
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 21, 2012
    Inventors: TIM BEAUMONT, MARK J. KWAKKENBOS, ERIC J. BROWN, JOHN H. MORISAKI, WOUTER L.W. HAZENBOS, SANJEEV MARIATHASAN, KIMBERLY KAJIHARA, YI XIA
  • Substituted pyrazole and triazole compounds as KSP inhibitors
    Patent number: 8129358
    Abstract: Disclosed are new substituted pyrazole and triazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof:
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: March 6, 2012
    Assignee: Novartis AG
    Inventors: Yi Xia, Kris G. Mendenhall, Paul A. Barsanti, Annette O. Walter, David Duhl, Paul A. Renhowe
  • Boron-containing small molecules as anti-inflammatory agents
    Patent number: 8039450
    Abstract: Compounds and methods of treating anti-inflammatory conditions are disclosed.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: October 18, 2011
    Assignee: Anacor Pharmaceuticals, Inc.
    Inventors: Tsutomu Akama, Yong-Kang Zhang, Charles Z. Ding, Jacob J. Plattner, Kirk R. Maples, Yvonne Freund, Virginia Sanders, Yi Xia, Stephen J. Baker, James A. Nieman, Xiaosong Lu, Marcelo Sales, Rashmi Sharma, Rajeshwar Singh, Robert Jacobs, Daitao Chen, Michael Richard Kevin Alley
  • Indole and benzimidazole derivatives
    Patent number: 8008335
    Abstract: The present invention relates to new indole and benzimidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula (I).
    Type: Grant
    Filed: October 14, 2005
    Date of Patent: August 30, 2011
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Rustum S. Boyce, Yi Xia, Hongyan Guo, Kris G. Mendenhall, Annette O. Walter, Weibo Wang
  • NOVEL TRIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
    Publication number: 20110136754
    Abstract: The present invention relates to novel compounds of formula (A): in the form of a free base or of an addition salt with an acid. The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers.
    Type: Application
    Filed: April 29, 2009
    Publication date: June 9, 2011
    Inventors: Ling Peng, Palma Rocchi, Juan Iovanna, Yi Xia, Fanqi Qu, Jinqiao Wan, Yang Liu, Menghua Wang
  • TRISUBSTITUTED BORON-CONTAINING MOLECULES
    Publication number: 20110136763
    Abstract: This invention largely relates to 3,4,6-trisubstituted benzoxaborole compounds, and their use for treating bacterial infections.
    Type: Application
    Filed: July 27, 2010
    Publication date: June 9, 2011
    Applicants: Anacor Pharmaceuticals, Inc., GlaxoSmithKline LLC
    Inventors: Yi Xia, Michael Richard Kevin Alley, Yasheen Zhou, Rajeshwar Singh, Charles Ding, Kathy Cao, Jacob J. Plattner, Ligong Ou, Guofeng Jia, Neerja Saraswat, Sreekanth Ramachandran, Ding Zhou
  • Substituted pyrazole and triazole compounds as KSP inhibitors
    Patent number: 7902240
    Abstract: Disclosed are new substituted pyrazole and triazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof:
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: March 8, 2011
    Assignee: Novartis AG
    Inventors: Yi Xia, Kris Mendenhall, Paul A. Barsanti, Annette O. Walter, David Duhl, Paul A. Renhowe
  • Method of fabicating a microelectronic die having a curved surface
    Patent number: 7888188
    Abstract: Microelectronic devices and methods for manufacturing microelectronic devices are disclosed herein. In one embodiment, a device includes a support member and a flexed microelectronic die mounted to the support member. The flexed microelectronic die has a plurality of terminals electrically coupled to the support member and an integrated circuit operably coupled to the terminals. The die can be a processor, memory, imager, or other suitable die. The support member can be a lead frame, a plurality of electrically conductive leads, and/or an interposer substrate.
    Type: Grant
    Filed: November 18, 2009
    Date of Patent: February 15, 2011
    Assignee: Micron Technology, Inc.
    Inventors: Tongbi Jiang, Zhong-Yi Xia, Sandhya Sandireddy
  • GRAM-POSITIVE BACTERIA SPECIFIC BINDING COMPOUNDS
    Publication number: 20110020323
    Abstract: The present invention provides improved binding compounds capable of specifically binding Gram-positive bacteria. Binding compounds are provided that are fully human, enabling therapeutic applications in human individuals.
    Type: Application
    Filed: July 15, 2010
    Publication date: January 27, 2011
    Inventors: Tim BEAUMONT, Mark J. Kwakkenbos, Eric J. Brown, John H. Morisaki, Wouter L.W. Hazenbos, Sanjeev Mariathasan, Kimberly Kajihara, Yi Xia
  • METHOD FOR REPAIRING MOTHERBOARD
    Publication number: 20110016687
    Abstract: A method is utilized for repairing a motherboard with a defective dual inline memory module (DIMM) socket mounted thereon be surface mounted technology (SMT). The method includes following steps. Repair tools including a ball grid array (BGA) rework device, a steel bar, a nozzle, and a steel sheet are provided. The BAG rework device, the nozzle are align with the defective DIMM on the motherboard for heating up solder balls between the defective DIMM and the motherboard until the solder balls are melted. The defective DIMM is removed from the motherboard. The steel bar is installed on a replacement DIMM to detect a planarity of a bottom face of the replacement DIMM. The replacement DIMM is mounted on the motherboard to replace the defective DIMM if the replacement DIMM is qualified.
    Type: Application
    Filed: October 22, 2009
    Publication date: January 27, 2011
    Applicants: HONG FU JIN PRECISION INDUSTRY (SHENZHEN) CO., LTD., HON HAI PRECISION INDUSTRY CO., LTD.
    Inventor: YI XIA
  • Tetrahydrocarboline compounds as anticancer agents
    Patent number: 7855295
    Abstract: Tetrahydrocarboline compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.
    Type: Grant
    Filed: January 24, 2005
    Date of Patent: December 21, 2010
    Assignee: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Weibo Wang, Zhi-Jie Ni, Paul Barsanti, Sabina Pecchi, Yi Xia, Nathan Brammeier, Megan C. Phillips, Eliza Jazan, Kelly Wayman, David Dibble, Jie-Kai Cheng
  • BORON-CONTAINING SMALL MOLECULES
    Publication number: 20100256092
    Abstract: This invention relates to, among other items, 6-substituted benzoxaborole compounds and their use for treating bacterial infections.
    Type: Application
    Filed: May 12, 2009
    Publication date: October 7, 2010
    Applicants: Anacor Pharmaceuticals, Inc., GlaxoSmithKline
    Inventors: Yi Xia, Michael Richard Kevin Alley, Yasheen Zhou, Vincent S. Hernandez, Jacob J. Plattner, Charles Z. Ding, Kathy Cao, Yong-Kang Zhang, Andrew Benowitz, Tsutomu Akama, Jessica Sligar, Guofeng Jia, Ligong Ou, Neerja Saraswat, Sreekanth Ramachandran, Chris Diaper, Yanchen Zhang, Goverdhan Reddy Banda, James A. Nieman, Mehdi Keramane, Rahim Mohammed, Rajendra Subedi, Hong Liang, Rajeshwar Singh