Patents by Inventor Yi Yan
Yi Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11690380Abstract: Antimicrobial cationic polycarbonates and polyurethanes have been prepared comprising one or more pendent guanidinium and/or isothiouronium groups. Additionally, antimicrobial particles were prepared having a silica core linked to surface groups comprising a guanidinium and/or isothiouronium group. The cationic polymers and cationic particles can be potent antimicrobial agents against Gram-negative microbes, Gram-positive microbes, and/or fungi.Type: GrantFiled: November 16, 2019Date of Patent: July 4, 2023Assignees: Coral Bay II, LLC, Agency For Science, Technology And ResearchInventors: Willy Chin, James L. Hedrick, Nor Lizawati Ibrahim, Ashlynn L. Z. Lee, Robert J. Ono, Qingxing Xu, Yi Yan Yang
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Publication number: 20230187540Abstract: The present disclosure describes a semiconductor structure and a method for forming the same. The semiconductor structure can include a substrate, a fin structure over the substrate, a gate structure over the fin structure, an epitaxial region formed in the fin structure and adjacent to the gate structure. The epitaxial region can embed a plurality of clusters of dopants.Type: ApplicationFiled: February 6, 2023Publication date: June 15, 2023Applicant: Taiwan Semiconductor Manufacturing Co., Ltd.Inventors: Chien-Wei Lee, Chii-Horng Li, Heng-Wen Ting, Yee-Chia Yeo, Yen-Ru Lee, Chih-Yun Chin, Chih-Hung Nien, Jing-Yi Yan
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Publication number: 20230122378Abstract: A water-soluble polymer having an aliphatic polycarbonate backbone, a first carbonate monomer with at least one hydrophilic functionality, and a second carbonate monomer with at least one hydrophobic functionality is able to completely and quickly eliminate a virus from a human and/or animal cell. The at least one hydrophilic functionality is a sulfate, a sulfonate, a carboxylate, and/or a phosphate and the at least one hydrophobic functionality is an alkyl. The hydrophilic/hydrophobic functionalities of the polymer may be tuned to enhance the antiviral properties of the polymer and/or to decrease any cytotoxicity associated with the application of the polymer to a human and/or animal cell. The antiviral polymer is biocompatible and biodegradable.Type: ApplicationFiled: October 5, 2021Publication date: April 20, 2023Inventors: James L. Hedrick, Yi Yan Yang, Agnes Mari Kuroki, Jiayu Eunice Leong, Wei Ping Eddy Tan
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Patent number: 11631745Abstract: A semiconductor structure includes a semiconductor substrate; fin active regions protruded above the semiconductor substrate; and a gate stack disposed on the fin active regions; wherein the gate stack includes a high-k dielectric material layer, and various metal layers disposed on the high-k dielectric material layer. The gate stack has an uneven profile in a sectional view with a first dimension D1 at a top surface, a second dimension D2 at a bottom surface, and a third dimension D3 at a location between the top surface and the bottom surface, and wherein each of D1 and D2 is greater than D3.Type: GrantFiled: April 2, 2021Date of Patent: April 18, 2023Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.Inventors: Chi-Sheng Lai, Yu-Fan Peng, Li-Ting Chen, Yu-Shan Lu, Yu-Bey Wu, Wei-Chung Sun, Yuan-Ching Peng, Kuei-Yu Kao, Shih-Yao Lin, Chih-Han Lin, Pei-Yi Liu, Jing Yi Yan
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Patent number: 11617367Abstract: Techniques regarding chemical compounds with antimicrobial functionality are provided. For example, one or more embodiments describe herein can comprise a monomer that can comprise a molecular backbone. The molecular backbone can comprise a bis(urea)guanidinium structure covalently bonded to a functional group, which can comprise a radical. Also, the monomer can have supramolecular assembly functionality.Type: GrantFiled: March 29, 2021Date of Patent: April 4, 2023Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: James L. Hedrick, Mareva B. Fevre, Nathaniel H. Park, Victoria A. Piunova, Yi Yan Yang, Pang Kern Jeremy Tan
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Patent number: 11575026Abstract: The present disclosure describes a semiconductor structure and a method for forming the same. The semiconductor structure can include a substrate, a fin structure over the substrate, a gate structure over the fin structure, an epitaxial region formed in the fin structure and adjacent to the gate structure. The epitaxial region can embed a plurality of clusters of dopants.Type: GrantFiled: March 19, 2021Date of Patent: February 7, 2023Assignee: Taiwan Semiconductor Manufacturing Co., Ltd.Inventors: Chien-Wei Lee, Chii-Horng Li, Heng-Wen Ting, Yee-Chia Yeo, Yen-Ru Lee, Chih-Yun Chin, Chih-Hung Nien, Jing-Yi Yan
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Patent number: 11572477Abstract: Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.Type: GrantFiled: November 8, 2019Date of Patent: February 7, 2023Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, Institute of Bioengineering and NanotechnologyInventors: Amos Cahan, Hariklia Deligianni, Xin Ding, Mareva B. Fevre, James L. Hedrick, Pei-Yun S. Hsueh, Zhen Chang Liang, Nathaniel H. Park, Theodore G. van Kessel, Rudy J. Wojtecki, Yi Yan Yang
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Publication number: 20230032345Abstract: Techniques regarding post polymerization modifications to polycarbonate polymers via a flow reactor are provided. For example, one or more embodiments described herein can comprise a cyclic carbonate monomer that can be employed to facilitate polymerization of one or more polycarbonate platforms susceptible to post polymerization modification. For instance, one or more embodiments can regard a cyclic carbonate molecular backbone covalently bonded to an aryl halide functional group via in accordance with a chemical structure selected from the group consisting of: In the chemical structures, “R1” can be selected from the group consisting of a hydrogen atom and a functional group comprising a first alkyl group; “L” can represent a linkage group, comprising: a second alkyl group and an end group having at least one member selected from the group consisting of an oxygen atom and a nitrogen atom; and “A” can represent the aryl halide functional group.Type: ApplicationFiled: September 23, 2022Publication date: February 2, 2023Inventors: Nathaniel H. Park, Victoria A. Piunova, Dmitry Zubarev, James L. Hedrick, Yi Yan Yang, Eddy Wei Ping Tan
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Patent number: 11559578Abstract: A method for formation of a vaccine comprising combining a cationic polymer adjuvant with an antigen to form first immunoparticles through charge interactions and producing a treatment formulation for the vaccine comprising the first immunoparticles.Type: GrantFiled: June 30, 2020Date of Patent: January 24, 2023Assignee: International Business Machines CorporationInventors: James L. Hedrick, Yi Yan Yang, Ashlynn Lee, Chuan Yang
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Patent number: 11560484Abstract: Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.Type: GrantFiled: November 8, 2019Date of Patent: January 24, 2023Assignees: International Business Machines Corporation, Institute of Bioengineering and NanotechnologyInventors: Amos Cahan, Hariklia Deligianni, Xin Ding, Mareva B. Fevre, James L. Hedrick, Pei-Yun S. Hsueh, Zhen Chang Liang, Nathaniel H. Park, Theodore G. van Kessel, Rudy J. Wojtecki, Yi Yan Yang
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Publication number: 20230018894Abstract: In examples, a method of manufacturing a transformer device comprises providing a first magnetic member and providing a laminate member containing primary and secondary transformer windings wound around an orifice extending through the laminate member. The method further comprises positioning a build up film abutting the laminate member. The method also comprises positioning at least a portion of a second magnetic member in the orifice. The method further comprises heat pressing at least one of the first and second magnetic members such that a distance between the first and second magnetic members decreases and such that the build-up film melts, thereby producing a transformer device.Type: ApplicationFiled: September 26, 2022Publication date: January 19, 2023Inventors: Zhemin ZHANG, Kenji OTAKE, Yi YAN, Jeffrey MORRONI, Yuki SATO, Takafumi ANDO
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Patent number: 11525036Abstract: Techniques regarding killing of a pathogen with one or more ionene compositions having antimicrobial functionality are provided. For example, one or more embodiments can comprise a method, which can comprise contacting a Mycobacterium tuberculosis microbe with a chemical compound. The chemical compound can comprise an ionene unit. Also, the ionene unit can comprise a cation distributed along a molecular backbone. The ionene unit can have antimicrobial functionality. The method can further comprise electrostatically disrupting a membrane of the Mycobacterium tuberculosis microbe in response to the contacting.Type: GrantFiled: October 16, 2020Date of Patent: December 13, 2022Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Mareva B. Fevre, James L. Hedrick, Nathaniel H. Park, Victoria A. Piunova, Pang Kern Jeremy Tan, Chuan Yang, Yi Yan Yang
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Publication number: 20220387596Abstract: The subject matter of this invention relates to hydrogel compositions and, more particularly, to hydrogel compositions comprising block copolymers (BCPs) capable of self-assembly into nanoparticles for the delivery and controlled release of therapeutic cargos.Type: ApplicationFiled: August 1, 2022Publication date: December 8, 2022Inventors: Mareva B. Fevre, James L. Hedrick, Ashlynn Lee, Nathaniel H. Park, Rudy J. Wojtecki, Yi Yan Yang, Zhi Xiang Voo
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Patent number: 11518849Abstract: Techniques regarding post polymerization modifications to polycarbonate polymers via a flow reactor are provided. For example, one or more embodiments described herein can comprise a cyclic carbonate monomer that can be employed to facilitate polymerization of one or more polycarbonate platforms susceptible to post polymerization modification. For instance, one or more embodiments can regard a cyclic carbonate molecular backbone covalently bonded to an aryl halide functional group via in accordance with a chemical structure selected from the group consisting of: In the chemical structures, “R1” can be selected from the group consisting of a hydrogen atom and a functional group comprising a first alkyl group; “L” can represent a linkage group, comprising: a second alkyl group and an end group having at least one member selected from the group consisting of an oxygen atom and a nitrogen atom; and “A” can represent the aryl halide functional group.Type: GrantFiled: May 22, 2020Date of Patent: December 6, 2022Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHInventors: Nathaniel H. Park, Victoria A Piunova, Dmitry Zubarev, James L. Hedrick, Yi Yan Yang, Eddy Wei Ping Tan
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Patent number: 11488914Abstract: In examples, a method of manufacturing a transformer device comprises providing a first magnetic member and providing a laminate member containing primary and secondary transformer windings wound around an orifice extending through the laminate member. The method further comprises positioning a build up film abutting the laminate member. The method also comprises positioning at least a portion of a second magnetic member in the orifice. The method further comprises heat pressing at least one of the first and second magnetic members such that a distance between the first and second magnetic members decreases and such that the build-up film melts, thereby producing a transformer device.Type: GrantFiled: September 24, 2019Date of Patent: November 1, 2022Assignee: TEXAS INSTRUMENTS INCORPORATEDInventors: Zhemin Zhang, Kenji Otake, Yi Yan, Jeffrey Morroni, Yuki Sato, Takafumi Ando
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Patent number: 11485823Abstract: The present invention mainly relates to a polymer for delivery of biologically active materials, a complex and a method of synthesis thereof. The polymer comprises a poly(ethylene imine) and at least one monomer, each monomer comprising a modified sugar moiety, preferably galactose, comprising a sulphur atom or a nitrogen atom and a chemical moiety comprising a terminal epoxide for linking the polyethylene imine to the monomer, wherein the sulphur atom or the nitrogen atom links the modified sugar moiety to the chemical moiety. The biologically active material is preferably a gene, siRNA, mRNA or plasmid DNA. Further disclosed is the medical use of said complex in treating a disease caused by a genetic disorder, for example cancer.Type: GrantFiled: May 23, 2018Date of Patent: November 1, 2022Assignee: Agency for Science, Technology and ResearchInventors: Yi-Yan Yang, Chuan Yang, Wei Cheng, Ashlynn Lee
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Patent number: 11478550Abstract: The subject matter of this invention relates to hydrogel compositions and, more particularly, to hydrogel compositions comprising block copolymers (BCPs) capable of self-assembly into nanoparticles for the delivery and controlled release of therapeutic cargos.Type: GrantFiled: November 21, 2018Date of Patent: October 25, 2022Assignees: INTERNATIONAL BUSINESS MACHINES CORPORATION, INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGYInventors: Mareva B. Fevre, James L. Hedrick, Ashlynn Lee, Nathaniel H. Park, Rudy J. Wojtecki, Yi Yan Yang, Zhi Xiang Voo
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Publication number: 20220310302Abstract: A microelectronic device includes a magnetic component having a first magnetic core segment and a second magnetic core segment, with a winding lamina between them. The first magnetic core segment includes a winding support portion with ferromagnetic material. The winding lamina is attached to the winding support portion. The first magnetic core segment also includes an extension portion with ferromagnetic material extending from the winding support portion. The winding lamina has winding loops of electrically conductive material that surround ferromagnetic material. A filler material is formed between the winding lamina and the first magnetic core segment, contacting both the winding lamina and the first magnetic core segment. The second magnetic core segment is attached to the extension portion of the first magnetic core segment. The second magnetic core segment includes ferromagnetic material. The winding loops are electrically coupled to external leads through electrical connections.Type: ApplicationFiled: March 29, 2021Publication date: September 29, 2022Inventors: Yi Yan, Zhemin Zhang, Ken Pham, Vijaylaxmi Khanolkar, Dongbin Hou
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Publication number: 20220302281Abstract: The present disclosure describes a semiconductor structure and a method for forming the same. The semiconductor structure can include a substrate, a fin structure over the substrate, a gate structure over the fin structure, an epitaxial region formed in the fin structure and adjacent to the gate structure. The epitaxial region can embed a plurality of clusters of dopants.Type: ApplicationFiled: March 19, 2021Publication date: September 22, 2022Applicant: Taiwan Semiconductor Manufacturing Co., Ltd.Inventors: Chien-Wei LEE, Chii-Horng LI, Heng-Wen TING, Yee-Chia YEO, Yen-Ru LEE, Chih-Yun CHIN, Chih-Hung NIEN, Jing Yi YAN
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Publication number: 20220265702Abstract: Techniques regarding a chemical composition that can be utilized within one or more combination therapies to treat a microbial infection are provided. For example, one or more embodiments described herein can comprise a chemical composition that includes a first triblock polymer comprising a quaternary ammonium functionalized polycarbonate block and exhibiting anticancer activity via a lytic mechanism. The chemical composition can also include a second triblock polymer comprising a guanidinium functionalized polycarbonate block and exhibiting anticancer activity via a translocation mechanism.Type: ApplicationFiled: April 14, 2022Publication date: August 25, 2022Inventors: James L. Hedrick, Yi Yan Yang, Nathaniel H. Park, Jiayu Leong, Chuan Yang, Xin Ding, Yiran Zhen, Cherylette Anne Alexander, Jye Yng Teo