Patents by Inventor Yih Chen

Yih Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9750844
    Abstract: The preset invention relates to a new method for wound healing, particularly in burns, comprising Epinecidin-1 (Epi-1) or Pardaxin (GE33), optionally in the incorporation into collagen.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: September 5, 2017
    Assignees: ACADEMIA SINICA, NATIONAL TAIWAN OCEAN UNIVERSITY
    Inventors: Jyh-Yih Chen, Chang-Jer Wu, Han-Ning Huang
  • Publication number: 20170170751
    Abstract: A piezoelectric energy harvesting apparatus includes a housing and a piezoelectric module disposed in the housing. The piezoelectric module includes a piezoelectric wafer unit and a clamp unit clamping the piezoelectric wafer unit. A resilient member is connected between the clamp unit and an inner wall of the housing to transmit an oscillation movement to the clamp unit, which in turn causes oscillation of the piezoelectric wafer unit for generating an electric power. An impact unit extends movably into the housing and is capable of pushing the clamp unit against the resilient member when being subjected to an ambient natural force such that the resilient member generates the oscillation movement.
    Type: Application
    Filed: September 30, 2016
    Publication date: June 15, 2017
    Inventors: Yang-Yih CHEN, Ray-Yeng YANG, Chia-Che WU, Jenn-Ming SONG
  • Publication number: 20170133793
    Abstract: A bidirectional access portable flash drive includes a casing, which defines therein a receiving space that receives a circuit board mounted therein. The circuit board has a surface on which a memory unit is mounted. The casing has an end to which a double-side pluggable micro-USB connector is mounted. The double-side pluggable micro-USB connector includes a frame and a plate mounted at a predetermined location in the frame. The plate has two surfaces each including a plurality of conductor elements mounted thereon. The plate has two ends at which at least one fixing element is mounted. The memory unit enables effective access and storage of data and the double-side pluggable micro-USB connector provides functions of double-side plugging and protection to achieve an effect of convenient transmission, access, and use of data.
    Type: Application
    Filed: November 6, 2015
    Publication date: May 11, 2017
    Inventors: Chang-Yih Chen, Chang-Lung Chen
  • Patent number: 9640912
    Abstract: A bidirectional access portable flash drive includes a casing, which defines therein a receiving space that receives a circuit board mounted therein. The circuit board has a surface on which a memory unit is mounted. The casing has an end to which a double-side pluggable micro-USB connector is mounted. The double-side pluggable micro-USB connector includes a frame and a plate mounted at a predetermined location in the frame. The plate has two surfaces each including a plurality of conductor elements mounted thereon. The plate has two ends at which at least one fixing element is mounted. The memory unit enables effective access and storage of data and the double-side pluggable micro-USB connector provides functions of double-side plugging and protection to achieve an effect of convenient transmission, access, and use of data.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: May 2, 2017
    Inventors: Chang-Yih Chen, Chang-Lung Chen
  • Patent number: 9623077
    Abstract: The present invention relates to a method for alleviating pain in a subject in need thereof, which comprises administering an effective amount of piscidin (PCD) peptide and a pharmaceutically acceptable carrier to the subject.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: April 18, 2017
    Assignees: ACADEMIA SINICA, NATIONAL SUN YAT-SEN UNIVERSITY
    Inventors: Zhi-Hong Wen, Jyh-Yih Chen
  • Publication number: 20170016894
    Abstract: The present invention relates to a method for detecting a target molecule, comprising forming a capturing complex comprising the target molecule; and binding the capturing complex with a signal amplifier, wherein the capturing complex has a net electrical charge; the signal amplifier has affinity to the capturing complex and has a like net electrical charge of the net electrical charge of the capturing complex. The invention improves the detection sensitivity and sensing limit of the detection.
    Type: Application
    Filed: July 14, 2016
    Publication date: January 19, 2017
    Inventors: Hardy Wai-Hong CHAN, Yuh-Shyong YANG, Wen-Yih CHEN
  • Publication number: 20170016051
    Abstract: The present invention relates to a method for detecting methylation of a target oligonucleotide molecule. The method comprises obtaining an electrical change occurring due to the binding of an electrically charged methylation detecting molecule and the target oligonucleotide molecule; wherein the electrically charged methylation detecting molecule has affinity to a methylated cytosine nucleotide. The invention improves the detection sensitivity and accuracy of the oligonucleotide methylation detection.
    Type: Application
    Filed: July 14, 2016
    Publication date: January 19, 2017
    Inventors: Hardy Wai-Hong CHAN, Yuh-Shyong YANG, Wen-Yih CHEN, Chang-Wei FU
  • Publication number: 20170015699
    Abstract: The present invention relates to a detection unit comprising a solid surface and a partially neutral single-stranded oligonucleotide comprising a first portion. The first portion is attached to the solid surface; the length of the first portion is about 50% of the total length of the partially neutral single-stranded oligonucleotide; and the first portion comprises at least one neutral nucleotide and at least one unmodified nucleotide. The invention improves the detection sensitivity and accuracy of the detection of biomolecules.
    Type: Application
    Filed: July 14, 2016
    Publication date: January 19, 2017
    Inventors: Hardy Wai-Hong CHAN, Yuh-Shyong YANG, Wen-Yih CHEN
  • Publication number: 20160346348
    Abstract: The present invention relates to a method for alleviating pain in a subject in need thereof, which comprises administering an effective amount of piscidin (PCD) peptide and a pharmaceutically acceptable carrier to the subject.
    Type: Application
    Filed: May 28, 2015
    Publication date: December 1, 2016
    Applicants: NATIONAL SUN YAT-SEN UNIVERSITY, ACADEMIA SINICA
    Inventors: Zhi-Hong Wen, Jyh-Yih Chen
  • Patent number: 9481905
    Abstract: A method of using Neutrilized DNA (N-DNA) as a surface probe for a high throughput detection platform is disclosed. FET and SPRi are used as high throughput detection platforms to demonstrate that the N-DNA surface probe produces good results and enhances detection sensitivity. The N-DNA modifies the charged oxygen ions (O?) on the phosphate backbone through methylation, ethylation, propylation, or alkylation, so that the backbone is not charged after this modification to increase the hybridization efficiency, sensitivity and to make the signal more clear.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: November 1, 2016
    Assignee: Orizhan Bioscience Limited
    Inventors: Wen-Yih Chen, Yuh-Shyong Yang, Hardy Wai-Hong Chan
  • Publication number: 20160310564
    Abstract: The preset invention relates to a new method for enhancing wound healing comprising administering a subject in need thereof with a therapeutically effective amount of a tilapia piscidin (TP), which is selected from the group consisting of TP1, TP2, TP3, TP4, TP5 and combination thereof. A composition or pharmaceutical composition comprising the TP are also provided.
    Type: Application
    Filed: April 25, 2016
    Publication date: October 27, 2016
    Inventors: Jyh-Yih CHEN, Chang-Jer WU
  • Publication number: 20160303190
    Abstract: The preset invention relates to a new method or composition for treating a gastric ulcer, preventing or treating an infection of H. pylori, particularly multidrug resistant H. pylori, using an antimicrobial peptide, a functional derivate, fragment or variant thereof, wherein the antimicrobial peptide is selected from the group consisting of Epi-1, TPs and combination thereof.
    Type: Application
    Filed: April 14, 2016
    Publication date: October 20, 2016
    Inventors: Jyh-Yih CHEN, Chang-Jer WU
  • Publication number: 20160193602
    Abstract: An oriented loading system is provided. The oriented loading system includes a substrate, a plurality of wells formed in the substrate, each well having a bottom and sidewalls, a plurality of particles loaded in the wells, wherein the particle comprises a core structure and an inner layer comprising magnetic material partially covering the core structure such that a part of the core structure uncovered by the inner layer is exposed, and a metal layer comprising magnetic material deposited partially in the sidewalls of the wells, wherein the inner layer is attracted by the metal layer such that the exposed core structure is oriented towards the bottom of the well or the inner layer is oriented towards the bottom of the well.
    Type: Application
    Filed: January 6, 2016
    Publication date: July 7, 2016
    Applicant: PERSONAL GENOMICS, INC.
    Inventors: Ching-Wei TSAI, Hsin-Yi HSIEH, Yu-Hsuan PENG, Wen-Yih CHEN, Chun-Jen HUANG
  • Patent number: 9346022
    Abstract: The present invention provides an antibiofouling composition, an antibiofouling membrane and a method for forming the same. The antibiofouling composition comprises a copolymer and at least one solvent. The copolymer comprises at least one hydrophobic segment and at least one antibiofouling segment where the hydrophobic segment comprises a plurality of hydrophobic moieties and the antibiofouling segment comprises a plurality of antibiofouling moieties. The molar ratio of the total of hydrophobic moieties to the total of the antibiofouling moieties is 0.5˜6.0.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: May 24, 2016
    Assignee: CHUNG YUAN CHRISTIAN UNIVERSITY
    Inventors: Yung Chang, Ruoh-chyu Ruaan, Yen-Che Chiag, Wen-Yih Chen
  • Publication number: 20160113252
    Abstract: The preset invention relates to a promoter to target a fluorescent protein to the muscles of fish, such as A. nigrofasciatus, for ornamental purposes, which is a Mlc3 (myosin, light polypeptide 3, skeletal muscle) promoter. The Mlc3 promoter has the nucleotides of tilapia (Oreochromis niloticus) myosin light chain 3 (Mlc3) promoter region, which is potential to be a tilapia Mlc3 promoter to enhance protein expression in muscle of fish, particularly for the generation of ornamental fish.
    Type: Application
    Filed: October 22, 2015
    Publication date: April 28, 2016
    Applicants: ACADEMIA SINICA
    Inventors: Yu-Ho LIN, Jyh-Yih CHEN
  • Patent number: 9312357
    Abstract: A semiconductor device and a method for manufacturing the same. The method includes steps hereinafter. A substrate is provided with a first dielectric layer thereon. The first dielectric layer is provided with a trench. Then, a metal layer is formed to fill the trench and to cover the surface of the first dielectric layer. The metal layer is partially removed so that a remaining portion of the metal layer covers the first dielectric layer. A treatment process is performed to transform the remaining portion of the metal layer into a passivation layer on the top portion and a gate metal layer on the bottom portion. A chemical-mechanical polishing process is performed until the first dielectric layer is exposed so that a remaining portion of the passivation layer remains in the trench.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: April 12, 2016
    Assignee: United Microelectronics Corporation
    Inventors: Shih-Chang Tsai, Tzu-Chin Tseng, Hsiao-Ting Lin, Chang-Yih Chen, Sam Lai
  • Publication number: 20160093712
    Abstract: A semiconductor device and a method for manufacturing the same. The method includes steps hereinafter. A substrate is provided with a first dielectric layer thereon. The first dielectric layer is provided with a trench. Then, a metal layer is formed to fill the trench and to cover the surface of the first dielectric layer. The metal layer is partially removed so that a remaining portion of the metal layer covers the first dielectric layer. A treatment process is performed to transform the remaining portion of the metal layer into a passivation layer on the top portion and a gate metal layer on the bottom portion. A chemical-mechanical polishing process is performed until the first dielectric layer is exposed so that a remaining portion of the passivation layer remains in the trench.
    Type: Application
    Filed: October 16, 2014
    Publication date: March 31, 2016
    Inventors: SHIH-CHANG TSAI, TZU-CHIN TSENG, HSIAO-TING LIN, CHANG-YIH CHEN, SAM LAI
  • Publication number: 20160082146
    Abstract: The preset invention relates to a new method for wound healing, particularly in burns, comprising Epinecidin-1 (Epi-1) or Pardaxin (GE33), optionally in the incorporation into collagen.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 24, 2016
    Applicant: ACADEMIA SINICA
    Inventors: Jyh-Yih CHEN, Chang-Jer WU, Han-Ning HUANG
  • Publication number: 20160046665
    Abstract: This invention discloses a peptide ligand with antibody selectivity and the application thereof. The peptide ligand with antibody selectivity comprises peptide ligand consisted of a sequence with 4 to 6 amino acids. The peptide ligand with antibody selectivity is able to bind with the hydrophobic region at the bottom of antibody's Fc region through non-covalent bonding. The mentioned peptide ligand with antibody selectivity can be applied to biochip for antibody oriented immobilization, and the biochip can provide high recognition efficiency to antigen. Besides, the mentioned peptide ligand with antibody selectivity can be applied as antibody purification material for purifying antibody with respective peptide ligand with antibody selectivity.
    Type: Application
    Filed: February 17, 2015
    Publication date: February 18, 2016
    Inventors: Ruoh-Chyu Ruaan, Ching-Wei Tsai, Siang-Long Jheng, Wei-Chih Tseng, Wen-Yih Chen
  • Publication number: 20150339599
    Abstract: The invention discloses system and method for electronic ticket peer-to-peer (P2P) secure transfer on mobile devices by NFC Technology, which supports mobile devices with NFC such as cell phone, and tablet. Electronic Ticket P2P Secure transfers on mobile devices by NFC. The system and method comprises two mobile devices with NFC technology, each of which comprises a secure element, an electronic ticket platform sub-system and a check-tickets reader sub-system.
    Type: Application
    Filed: May 25, 2015
    Publication date: November 26, 2015
    Inventors: Wei-Hsun LEE, Wei-Jeng WU, Yu-Sin LEE, Chuen-Yih CHEN, Dung-Ying LIN