Patents by Inventor YiHong Li

YiHong Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047344
    Abstract: Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, or a stereoisomer thereof; and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 18, 2021
    Applicant: AMGEN INC.
    Inventors: Gwenaella RESCOURIO, Ana GONZALEZ BUENROSTRO, Sean P. BROWN, Mike LIZARZABURU, Julio MEDINA, Salman Yojiro JABRI, Daqing SUN, Scott Preston SIMONOVICH, Xuelei YAN, Yihong LI, Yosup REW
  • Patent number: 10910877
    Abstract: Methods and devices for increasing power delivery efficiency of wireless power transfer systems are disclosed. A wireless power transfer system may include a power transmitter system and a power receiver system. The power transmitter system may comprise a power amplifier, a power transmitter, a controller, and a sensing circuit. The power amplifier may be configured to receive an input power. The power transmitter system may include a transmitter-side coil configured to wirelessly couple to a receiver-side coil of the power receiver system. The controller may be configured to set a voltage and a frequency of the power transmitter system based on output power information of the power receiver system to increase wireless power delivery efficiency of the wireless power transfer system. The sensing circuit may be configured to determine the output power information of the power receiver system.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: February 2, 2021
    Assignee: SHENZHEN YICHONG WIRELESS POWER TECHNOLOGY CO. LTD
    Inventors: Siming Pan, Tun Li, Dawei He, Yihong Dai, Jingdong Sun
  • Publication number: 20210025103
    Abstract: A method and apparatus for breaking a unit dose package in a chamber within a post located in a basket of a laundry washing machine. The method includes filling the basket and the chamber, increasing a rotation speed of the basket and/or the post to raise the water level in the basket and lower the water level in the chamber to cause a unit dose package within the chamber to move downwards; reducing the rotation speed to lower the water level in the basket and raise the water level in chamber to cause the unit dose package within the chamber to move upwards; and repeating the steps of increasing and reducing the rotational speed to cause the unit dose package to break open and at least partially dissolve. A laundry washing machine configured to perform this process is also provided.
    Type: Application
    Filed: July 25, 2019
    Publication date: January 28, 2021
    Inventors: Yihong Li, Anthony Lufkin, Allison White, Terry Anderson
  • Publication number: 20210014174
    Abstract: A method, a device, and a system for transmitting a multicast packet are provided. The method includes: when a device that is in a source subnet and that is connected to a core network receives a multicast packet of a target multicast group, determining addresses of devices that are in a plurality of destination subnets corresponding to the target multicast group and that are connected to the core network, replicating the multicast packet, to obtain a plurality of multicast packets whose quantity is equal to a quantity of the plurality of destination subnets, separately adding outer encapsulation to each multicast packet, and forwarding the multicast packet to which the outer encapsulation is added, where a destination address in the outer encapsulation is an address of a device that is in each destination subnet and that is connected to the core network.
    Type: Application
    Filed: September 25, 2020
    Publication date: January 14, 2021
    Inventors: Nu Xia, Jian Chen, Xia Zhu, Jun Zhou, Yihong Huang, Ji Li, Naiwen Wei
  • Patent number: 10879736
    Abstract: Methods, systems, and devices for wirelessly providing power to devices using a non-resonant power receiver are disclosed. A transmitter-side inductor may be inductively coupled to a receiver-side inductor. The transmitter-side inductor and one or more transmitter-side matching capacitors may be included in a power transmitter. The receiver-side inductor may be included in a power receiver. The power receiver may not include a receiver-side matching capacitor. Power from the power transmitter may be provided to the power receiver via the inductive coupling between the transmitter-side inductor and the receiver-side inductor. The power receiver may provide a reflected impedance including a real part and an imaginary part to the power transmitter. The transmitter-side matching capacitor(s) may compensate for the imaginary part of the reflected impedance.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: December 29, 2020
    Assignee: SHENZHEN YICHONG WIRELESS POWER TECHNOLOGY CO. LTD
    Inventors: Tun Li, Dawei He, Siming Pan, Yihong Dai, Jingdong Sun
  • Publication number: 20200379779
    Abstract: This application provides a program operating method and a related apparatus. The method includes obtaining first operating data of the program from a server, the first operating data comprising at least an instruction for starting the program; executing the first operating data, and displaying a first page of the program according to the first operating data; determining, in response to a second triggering instruction of a control in the first page, a second page identifier corresponding to the control; obtaining second operating data from the server according to the second page identifier if operating data corresponding to the second page identifier is not in the first operating data, the second operating data comprising the operating data corresponding to the second page identifier; and executing the second operating data, and displaying a second page according to the second operating data, the second operating data comprising portions of the program.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Inventors: Zhaopeng LIANG, Shangtao LIANG, Shun LI, Xing LIN, Chao LIN, Canhui HUANG, Xuyu GUI, Haojun HU, Yihong YANG, Weibang LUO, Yaxuan LI, Zhe CHENG, Qingjie LIN, Yu WU, Taotao XIAO
  • Publication number: 20200379307
    Abstract: The present disclosure provides an array substrate, a manufacturing method of an array substrate, and a display device. The array substrate includes: a base substrate; a first signal line, extending in a first direction and located on the base substrate; a second signal line, extending in a second direction and located on a side of the first signal line away from the base substrate and insulated with the first signal line, the first direction and the second direction crossing with each other. A side of the first signal line facing the second signal line is provided with a groove, the groove is located at a crossing region between the first signal line and the second signal line, in the crossing region, an otherographic projection of the second signal line on the base substrate completely falls into an orthographic projection of the groove on the base substrate.
    Type: Application
    Filed: January 25, 2018
    Publication date: December 3, 2020
    Inventors: Guolin ZHANG, Jiuyang CHENG, Jiahong ZOU, Wenhao XIAO, Junliang LI, Yihong MA
  • Publication number: 20200362048
    Abstract: The present invention provides a BCMA-targeted chimeric antigen receptor (CAR) as well as a preparation method therefor and an application thereof. Specifically, the present invention provides the BCMA-targeted CAR, which comprises a BCMA-targeted scFv, a hinge region, a transmembrane region, and an intracellular signal structure domain. The present invention provides a nucleic acid molecule for coding the CAR and a corresponding expression vector as well as CAR-T cells and application thereof. The CAR of the present invention targets BCMA-positive cells, and can be used for treating BCMA-positive B-cell lymphoma, multiple myeloma and plasma cell leukemia.
    Type: Application
    Filed: May 22, 2020
    Publication date: November 19, 2020
    Applicant: CELLULAR BIOMEDICINE GROUP HK LIMITED
    Inventors: Yutian WEI, Lin ZHU, Yanfeng LI, Yihong YAO, Xin YAO, Jiaqi HUANG, Li ZHANG, Shigui ZHU, Xiaoteng LV
  • Publication number: 20200087828
    Abstract: A method for controlling a laundry washing machine. The method includes: performing a tub loading process comprising operating supply valve(s) to provide a first volume of water through a detergent supply system and into a tub to fill the tub with wash liquid; performing a washing process comprising rotating a drum to agitate laundry in in the presence of the wash liquid; performing a static rinsing process comprising operating a pump to remove any free volume of wash liquid from the tub without rotating the drum; and performing one or more rinsing processes comprising: operating the supply valve(s) to provide a volume of clean rinse water to the tub, operating the pump to remove the rinse water from the drum, and operating the motor to spin the drum at high speed to extract rinse water from the laundry, while continuing to operate the pump.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Allison White, Martino Bondi, Yihong Li, Elisa Stabon, Alberto Lucchetta
  • Publication number: 20200087837
    Abstract: A laundry washing machine having: a casing, a washing tub located within the casing, a drum mounted within the washing tub and configured to rotate relative to the casing, a door attached to the casing and being openable to provide access to the drum, an additive loading and supply system configured to receive loose detergent, one or more valves configured to selectively provide water to the additive loading and supply system, a tub supply pipe fluidly connecting the additive loading and supply system to the drum, a receptacle configured to receive a unit dose package comprising a water soluble pouch containing a dose of cleaning product, and means for breaking the unit dose package outside the additive loading and supply system.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Helena Romito, Allison White, Yihong Li, Oscar Madalena
  • Publication number: 20200087839
    Abstract: A laundry washing machine and a method for operating the washing machine offer ways to load a unit dose package into a compartment of the washing machine. A control unit controls the washing machine to add water to a compartment having a unit dose package. The tub is then filled with hot or cold water depending on the temperature of the water in the tub, or whether a sanitizing cycle of a washing program has been selected.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Allison White, Yihong Li, Oscar Madalena
  • Publication number: 20200087838
    Abstract: A laundry washing machine having a casing, a washing tub within the casing, a drum within the washing tub, a door to provide access to the drum, an additive loading and supply system configured to receive one or more cleaning products, a soaking chamber configured to receive and hold a unit dose package and at least a first volume of liquid, a tub supply pipe connecting the soaking chamber to the washing tub and/or drum, valves to dispense water into the soaking chamber, and a control unit operatively connected to the valves. The control unit has instructions that, when executed: cause the valves to supply the first volume of liquid to the soaking chamber, allow the first volume of liquid to reside in the soaking chamber for a predetermined amount of time, and subsequently release the first quantity of liquid from the soaking chamber to the tub supply pipe.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Allison White, Yihong Li, Oscar Madalena
  • Publication number: 20200087835
    Abstract: A laundry washing machine having a casing, a washing tub located within the casing, a drum mounted within the washing tub and configured to rotate relative to the casing, a door attached to the casing and being openable to provide access to the drum, a receptacle configured to receive a unit dose package comprising a water soluble pouch containing a dose of cleaning product, a tub supply pipe fluidly connecting the receptacle to washing tub, and means for mechanically breaking the unit dose package.
    Type: Application
    Filed: September 14, 2018
    Publication date: March 19, 2020
    Inventors: Allison White, Yihong Li, Oscar Madalena
  • Patent number: 10560382
    Abstract: A data transmission method and an apparatus are provided. The data transmission method in the present invention includes: determining, by a first device and according to data stream information, whether a data transfer protocol TCP parameter in a data stream corresponding to the data stream information needs to be modified, where the data stream information includes at least one of the following information: information about the first device, information about a second device, service information, or network status information; if determining that the TCP parameter needs to be modified, modifying, by the first device, the TCP parameter, to obtain a modified TCP parameter; and generating, by the first device, a modification result of the TCP parameter.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: February 11, 2020
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Jin Li, Feng Li, Yihong Huang
  • Patent number: 10538890
    Abstract: A hydraulic ship lift, including: a mechanical synchronizing system; a stabilizing and equalizing hydraulic driving system; and a self-feedback stabilizing system. The stabilizing and equalizing hydraulic driving system includes first resistance equalizing members arranged at corners of branch water pipes or/and second resistance equalizing members arranged at bifurcated pipes, circular forced ventilating mechanisms arranged at front of water delivery valves of a water delivery main pipe, and pressure-stabilizing and vibration-reducing boxes arranged behind the water delivery valves. The self-feedback stabilizing system includes a plurality of guide wheels; each guide wheel of the self-feedback stabilizing system is fixed on a ship reception chamber through a supporting mechanism.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 21, 2020
    Assignees: HUANENG LANCANG RIVER HYDROPOWER INC., POWER CHINA KUNMING ENGINEERING CORPORATION LIMITED, NANJING HYDRAULIC RESEARCH INSTITUTE, CHINA INSTITUTE OF WATER RESOURCES AND HYDROPOWER RESEARCH
    Inventors: Hongqi Ma, Yaan Hu, Zongliang Zhang, Xianghua Yuan, Zejiang Xiang, Yongping Al, Yimin Chuan, Guanqun Nan, Rui Zou, Zhaoxin Chen, Xiaolin Hu, Hongtao Zhang, Haibin Xiao, Qun Huang, Keheng Zhou, Xuexing Cao, Zichong Li, Renchao Ma, Yinan Cao, Yun Ling, Sisi Xie, Junyang Yu, Zhonghua Li, Yun Li, Guoxiang Xuan, Xin Wang, Xiujun Yan, Shu Xue, Chao Guo, Yue Huang, Yihong Wu, Rui Zhang, Dong Zhang, Jinxiong Zhang, Wenyuan Zhang, Hongwei Zhang, Jianbiao Gao
  • Publication number: 20200002400
    Abstract: Provided are a chimeric antigen receptor targeting CD20 antigen and a preparation method thereof. The extracellular antigen binding domain of the chimeric antigen receptor includes an antibody heavy chain variable region shown in SEQ ID NO: 7 or 9 or 33 and an antibody light chain variable region shown in SEQ ID NO: 11 or 13 or 35, and is capable of killing tumor cells.
    Type: Application
    Filed: February 8, 2018
    Publication date: January 2, 2020
    Applicants: CELLULAR BIOMEDICINE GROUP (SHANGHAI) LTD., CELLULAR BIOMEDICINE GROUP (WUXI) LTD.
    Inventors: Yihong YAO, Jiaqi HUANG, Shigui ZHU, Wei ZHU, Xin YAO, Zhiyuan LI, Li ZHANG, Lin ZHU, Anyun MA, Yutian WEI, Yanfeng LI, Qingxia WANG, Jiaping HE
  • Publication number: 20190062276
    Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.
    Type: Application
    Filed: March 21, 2018
    Publication date: February 28, 2019
    Inventors: Michael D. Bartberger, Ana Gonzalez Buenrostro, Hilary Plake Beck, Xiaoqi Chen, Richard Victor Connors, Jeffrey Deignan, Jason A. Duquette, John Eksterowicz, Benjamin Fisher, Brian M. Fox, Jiasheng Fu, Zice Fu, Felix Gonzalez Lopez De Turiso, Michael W. Gribble, JR., Darin J. Gustin, Julie A. Heath, Xin Huang, XianYun Jiao, Michael G. Johnson, Frank Kayser, David John Kopecky, SuJen Lai, Yihong Li, Zhihong Li, Jiwen Liu, Jonathan D. Low, Brian S. Lucas, Zhihua Ma, Lawrence R. McGee, Joel McIntosh, Dustin L. McMinn, Julio C. Medina, Jeffrey Thomas Mihalic, Steven H. Olson, Yosup Rew, Philip M. Roveto, Daqing Sun, Xiaodong Wang, Yingcai Wang, Xuelei Yan, Ming Yu, Jiang Zhu
  • Patent number: 9758495
    Abstract: The present invention provides MDM2 inhibitor compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor of Formula (I).
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 12, 2017
    Assignee: Amgen Inc.
    Inventors: Ana Gonzalez Buenrostro, Yihong Li, Julio C. Medina, Steven H. Olson
  • Publication number: 20170252468
    Abstract: The present invention discloses a technique of preparation of composite nanodots, and their use in the field of photoacoustic imaging, wherein, the main components of the composition are carbon nanodots, and supporting component is methylene blue, and the composition has favourable biocompatibility characteristics with the average grain size of 150-300 nanometers, and the average zeta potential of ?15 to 5 millivolts. The above said techniques for preparation of composite nanodots are safe, quick and simple, low cost, and easy to perform for industrialized production. Composite carbon nanodots have good biocompatibility and safety, high photoacoustic imaging sensitivity, and it is promising in gaining wider use in the fields of biomedical imaging, targeting diagnosis and therapy, drug screening and optimization, and in vivo labelling and tracing, and has potential value in personalized medicine.
    Type: Application
    Filed: March 1, 2016
    Publication date: September 7, 2017
    Inventors: Zhe Liu, Qien Xu, Yuanhui Song, Yihong Li
  • Publication number: 20170216461
    Abstract: The present invention discloses a preparation technique of composite nanodots based on carbon nanodots, and their use in the field of fluorescent imaging, wherein, the main components of the composition are carbon nanodots, which are material with superior biocompatibility characteristics, and supporting component is methylene blue, and particle diameter range is 100-500 nanometers, and the zeta potential is ?35 to 10 millivolts. The above said techniques for preparation of composite nanodots are safe, quick and simple, low cost, and easy to perform for industrialized production. Composite carbon nanodots have good biocompatibility and safety, high fluorescence imaging sensitivity, and they are promising in gaining wider use in the fields of biomedical imaging, targeting diagnosis and therapy, drug screening and optimization, and in vivo labelling and tracing, and have potential value in personalized medicine.
    Type: Application
    Filed: February 1, 2016
    Publication date: August 3, 2017
    Inventors: Zhe Liu, Qien Xu, Yuanhui Song, Yihong Li