Abstract: A laundry washing machine and a method for operating the washing machine offer ways to load a unit dose package into a compartment of the washing machine. A control unit controls the washing machine to add water to a compartment having a unit dose package. The tub is then filled with hot or cold water depending on the temperature of the water in the tub, or whether a sanitizing cycle of a washing program has been selected.

Abstract: Provided herein are compounds identified as inhibitors of HDAC6 activity having the formula: or a pharmaceutically acceptable salt thereof, that can be used to treat various diseases and disorders.

Abstract: A system and method for monitoring medication intake uses vibration signals generated by a kinetic augmentation attachment. The attachment includes a base coupled to a medication container, a spring, and a weight, which produces distinct vibration signatures when the container is placed on a surface. A vibration sensor detects these signals, and a computing device processes them to extract features of the attachment and identify the medication container. The system does not require batteries, enabling long-term, maintenance-free monitoring. The method includes processing vibration signals using frequency analysis and machine learning to recognize different medication containers based on their kinetic signatures.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: A laundry washing machine and a method for operating the washing machine offer ways to load a unit dose package into a compartment of the washing machine. A control unit controls the washing machine to add water to a compartment having a unit dose package. The tub is then filled with hot or cold water depending on the temperature of the water in the tub, or whether a sanitizing cycle of a washing program has been selected.

Abstract: A method and apparatus for breaking a unit dose package in a chamber within a post located in a basket of a laundry washing machine. The method includes filling the basket and the chamber, increasing a rotation speed of the basket and/or the post to raise the water level in the basket and lower the water level in the chamber to cause a unit dose package within the chamber to move downwards; reducing the rotation speed to lower the water level in the basket and raise the water level in chamber to cause the unit dose package within the chamber to move upwards; and repeating the steps of increasing and reducing the rotational speed to cause the unit dose package to break open and at least partially dissolve. A laundry washing machine configured to perform this process is also provided.

Abstract: A laundry washing machine having: a casing; a washing tub in the casing; a rotatable drum mounted within the washing tub; a door to provide access to the drum; a receptacle having a volume configured to receive a unit dose package comprising a water soluble pouch containing a dose of cleaning product; a tub supply pipe connecting the receptacle to the washing tub; one or more protrusions movably mounted to the casing to move between a first position in which the one or more protrusions are not located within the volume configured to receive the unit dose package, and a second position in which the one or more protrusions are located within the volume configured to receive the unit dose package; and a motor configured to move the one or more protrusions from the first position to the second position. Methods for operating a laundry washing machine are also provided.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds.

Abstract: A composition and method for durable odor control on a textile are provided. The composition contains benzoic acid; a salt of benzoic acid; non-benzoic acid, a salt of non-benzoic acid, or a combination thereof. The composition may further contain an optional binder. Methods of application of the composition include padding and exhaustion.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: A method and apparatus for breaking a unit dose package in a chamber within a post located in a basket of a laundry washing machine. The method includes filling the basket and the chamber, increasing a rotation speed of the basket and/or the post to raise the water level in the basket and lower the water level in the chamber to cause a unit dose package within the chamber to move downwards; reducing the rotation speed to lower the water level in the basket and raise the water level in chamber to cause the unit dose package within the chamber to move upwards; and repeating the steps of increasing and reducing the rotational speed to cause the unit dose package to break open and at least partially dissolve. A laundry washing machine configured to perform this process is also provided.

Abstract: A method for reducing microbial growth and odor on a textile material are provided. The method comprises applying a composition to a textile material. The composition consists of a salt of benzoic acid; a non-benzoic acid consisting of sorbic acid, citric acid, lactic acid, acetic acid, L-glutamic acid, trisodium citrate, potassium sorbate, and combinations thereof. The composition has a weight ratio of salt of benzoic acid to non-benzoic acid ranging from 1:3 to 10:1 and the composition reduces microbial growth on the textile after laundering.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: Antimicrobial and/or anti-odor textile coating composition that reduce and/or prevent bacterial growth and/or control odor(s) on a textile material treated for a prolonged time period including up to, for example, fifty wash cycles. The textile coating compositions may include benzoic acid and at least one of terephthalic acid, and/or a quat silane.

Abstract: The present invention provides MDM2 inhibitor compounds of Formula I, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.

Abstract: A laundry washing machine having: a casing; a washing tub in the casing; a rotatable drum mounted within the washing tub; a door to provide access to the drum; a receptacle having a volume configured to receive a unit dose package comprising a water soluble pouch containing a dose of cleaning product; a tub supply pipe connecting the receptacle to the washing tub; one or more protrusions movably mounted to the casing to move between a first position in which the one or more protrusions are not located within the volume configured to receive the unit dose package, and a second position in which the one or more protrusions are located within the volume configured to receive the unit dose package; and a motor configured to move the one or more protrusions from the first position to the second position. Methods for operating a laundry washing machine are also provided.

Abstract: A laundry washing machine and a method for operating the washing machine offer ways to load a unit dose package into a compartment of the washing machine. A control unit controls the washing machine to add water to a compartment having a unit dose package. The tub is then filled with hot or cold water depending on the temperature of the water in the tub, or whether a sanitizing cycle of a washing program has been selected.