Abstract: A method of forming a structure having a coating layer includes the following steps: providing a substrate; coating a fluid on the surface of the substrate, where the fluid includes a carrier and a plurality of silicon-containing nanoparticles; and performing a heating process to remove the carrier and convert the silicon-containing nanoparticles into a silicon-containing layer, a silicide layer, or a stack layer including the silicide layer and the silicon-containing layer.

Abstract: A method for deploying product applications within virtual machines onto on-premises and public cloud infrastructures. Specifically, the disclosed method proposes a migration scheme of virtual machine images (configured at least with product applications and guest operating systems) from an on-premises infrastructure to a public cloud infrastructure. Further, the migration scheme considers two workflows—a normal workflow contingent on the public cloud infrastructure having up-to-date support for the guest operating systems; and an exception workflow contingent on the public cloud infrastructure lacking up-to-date support for the guest operating systems.

Abstract: Methods, apparatuses and systems for providing a switching component are disclosed herein. An example switching component may comprise: A switching component comprising: a housing; a carrier body disposed within the housing; a first pair of contact pads disposed on a first surface of the carrier body; and a second pair of contact pads disposed on a second surface of the carrier body, wherein each pair of contact pads is configured to independently make contact with adjacent bridge contact pads in order to actuate an electrical bridge in response to movement of the carrier body.

Abstract: Methods, apparatuses and systems for providing a switching component are disclosed herein. An example switching component may include: a housing, a moveable carrier disposed within the housing, a set of moveable contacts, wherein a central body of the set of moveable contacts is disposed flush between a first surface of the moveable carrier and a second surface of the moveable carrier, and a set of stationary contacts adjacent the set of moveable contacts, wherein the set of moveable contacts is configured to move with a degree of freedom to make contact with the set of stationary contacts in order to actuate an electrical bridge in response to movement of the moveable carrier.

Abstract: A composite for generating hydrogen includes several core-shell structures, each of which include a silicon-containing core and a shell covering the surface of the silicon-containing core. The shell includes a hydrophilic layer covering the surface of the silicon-containing core and an alkali material covering the hydrophilic layer.

Abstract: A composite material for electrode includes electrode composite particles, each of which includes a core and a shell. Each core includes carbon matrix, multiple active nanoparticles and multiple graphite particles. The active nanoparticles and the graphite particles are randomly dispersed in the carbon matrix. Each shell covers the surface of each core, and the Mohs hardness of the shell is greater than 2.

Abstract: Disclosed herein are systems and methods for detecting and mitigating inappropriate behavior. The systems and methods may include receiving data. Using the data a harassment score and/or classification for a behavior may be determined. Using the harassment score and/or classification, a determination may be made as to when the harassment score and/or classification for the behavior exceeds a threshold. When the threshold is exceeded, a protection system and/or action engine may be activated to mitigate the inappropriate behavior.

Abstract: The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.

Abstract: A composite for generating hydrogen includes several core-shell structures, each of which include a silicon-containing core and a shell covering the surface of the silicon-containing core. The shell includes a hydrophilic layer covering the surface of the silicon-containing core and an alkali material covering the hydrophilic layer.

Abstract: A process for modifying glycoproteins is provided. The invention also provides a process for producing glycoprotein-payload conjugates, as well as the conjugates produced thereby.

Abstract: A composite particle for electrode includes a carbon matrix, a plurality of active nanoparticles and a plurality of graphite particles. The active nanoparticles are randomly dispersed in the carbon matrix. Each of the active nanoparticles includes an active material and a protective layer. The protective layer covers the active material, and the protective layer is an oxide, a carbide or a nitride of the active material. The graphite particles are randomly dispersed in the carbon matrix. A volume fraction of the protective layer in each of the active nanoparticles is smaller than 23.0%.

Abstract: An immunoconjugate includes an anti-Globo H antibody, or a binding fragment thereof, and a therapeutic agent or a label, having the formula: Ab?(L?D)m, wherein Ab is the anti-Globo H antibody or the binding fragment thereof, L is a linker or a direct bond, D is the therapeutic agent or the label, and m is an integer from 1 to 8. The antibody may be a monoclonal antibody, which may be a humanized antibody. A method for treating a cancer includes administering to a subject in need of such treatment a pharmaceutically effective amount of an immunoconjugate containing an antibody against Globo H, or a binding fragment thereof, and a therapeutic agent covalently conjugated with the antibody.

Abstract: The present invention relates to benzoxazole derivatives having the following Formula (I): The compounds of the present invention are found to possess the ability to decrease PD-L1 level, suggesting that the compounds of the invention can be used in cancer immunotherapy and treatment or prevention of sepsis or septic shock.

Abstract: The present invention relates to a miniature finger gyro boomerang, comprising a main body casing, a propeller being arranged in the main body casing, and a shaft being arranged in the center of the propeller. Both ends of the shaft are penetrated with a finger pressing top bracket and a finger pressing bottom bracket, and the finger pressing top bracket and the finger pressing bottom bracket are respectively disposed on the top and the bottom sides of the main body casing. A drive component, a main control board and a power supply are provided in the main body casing, the power supply is electrically connected to the main control board, the main control board is electrically connected to the drive component, a motor cover of the drive component is linked with the main body casing, and the driving motor shaft is drivingly connected to the propeller.

Abstract: A composite particle for electrode includes a carbon matrix, a plurality of active nanoparticles and a plurality of graphite particles. The active nanoparticles are randomly dispersed in the carbon matrix. Each of the active nanoparticles includes an active material and a protective layer. The protective layer covers the active material, and the protective layer is an oxide, a carbide or a nitride of the active material. The graphite particles are randomly dispersed in the carbon matrix. A volume fraction of the protective layer in each of the active nanoparticles is smaller than 23.0%.

Abstract: A process for modifying glycoproteins is provided. The invention also provides a process for producing glycoprotein payload conjugates, as well as the conjugates produced thereby.

Abstract: The present invention illustrates a conductive composite material, and a negative electrode materials and a secondary battery containing the same. The conductive composite material includes a core, an inner coating layer and an outer coating layer. The core is made of a first material selected from a group consisting of WA element, metal, metal compound or alloy. The inner coating layer is existed on the core and made of oxide, nitride or carbide of the first material. The outer coating layer is existed on the inner coating layer and made of a carbon material and a second material containing halogen or VA element.