Patents by Inventor Ying-Fei Wei

Ying-Fei Wei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 44 human secreted proteins
    Publication number: 20050153335
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 3, 2004
    Publication date: July 14, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • 44 human secreted proteins
    Publication number: 20050079537
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: December 3, 2004
    Publication date: April 14, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • Methods for diagnosing cancer and determining a susceptibility for developing cancer
    Publication number: 20050074755
    Abstract: A human mutY polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating diseases associated with a mutation in this gene. Diagnostic assays for identifying mutations in nucleic acid sequence endcoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, area also disclosed.
    Type: Application
    Filed: February 12, 2003
    Publication date: April 7, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventor: Ying-Fei Wei
  • 83 human secreted proteins
    Publication number: 20050037467
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: September 9, 2004
    Publication date: February 17, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven Ruben, Ping Feng, David LaFleur, Paul Moore, Yanggu Shi, Hla Kyaw, Yi Li, ZhiZhen Zeng, Kenneth Carter, Gregory Endress, Ying-Fei Wei, Ping Fan, Craig Rosen
  • 44 Human secreted proteins
    Publication number: 20050009085
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: August 16, 2004
    Publication date: January 13, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: David LaFleur, Steven Ruben, Craig Rosen, Paul Moore, Yanggu Shi, Hla Kyaw, Ying-Fei Wei
  • Transforming growth factor alpha Hlll
    Publication number: 20040229787
    Abstract: The present invention discloses transforming growth factor alpha HIII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptide and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
    Type: Application
    Filed: November 21, 2003
    Publication date: November 18, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventor: Ying-Fei Wei
  • 125 human secreted proteins
    Publication number: 20040185440
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 28, 2001
    Publication date: September 23, 2004
    Inventors: Ping Feng, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Henrik S. Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter
  • Transforming growth factor alpha HII
    Publication number: 20040146510
    Abstract: The present invention discloses transforming growth factor alpha HII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders, and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
    Type: Application
    Filed: August 21, 2003
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Ying-Fei Wei, Paul S. Meissner, Jian Ni
  • 94 human secreted proteins
    Publication number: 20040146930
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • 95 human secreted proteins
    Publication number: 20040048304
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: September 3, 2003
    Publication date: March 11, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Guo-Liang Yu, Paul Young, Ping Feng, Daniel R. Soppet, Ying-Fei Wei, Gregory A. Endress, Roxanne Duan, Hla Kyaw, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore
  • 125 human secreted proteins
    Publication number: 20040038277
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 18, 2003
    Publication date: February 26, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Ping Feng, Steven M. Ruben, Reinhard Ebner, Henrik Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter, Charles E. Birse
  • 98 human secreted proteins
    Publication number: 20040034196
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 27, 2003
    Publication date: February 19, 2004
    Inventors: George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, D. Roxanne Duan, Paul A. Moore, Yanggu Shi, David W. LaFleur, Ying-Fei Wei
  • 29 human secreted proteins
    Publication number: 20040023260
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: February 27, 2003
    Publication date: February 5, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Ping Fan, Hla Kyaw, Ying-Fei Wei
  • 28 human secreted proteins
    Publication number: 20030225009
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 30, 2002
    Publication date: December 4, 2003
    Inventors: Craig A. Rosen, Steven M. Ruben, Yi Li, ZhiZhen Zeng, Hla Kyaw, Carrie L. Fischer, Haodong Li, Daniel R. Soppet, Reiner L. Gentz, Ying-Fei Wei, Paul A. Moore, Paul E. Young, John M. Greene, Ann M. Ferrie, Gregg A. Hastings
  • Human DNA Ligase III
    Publication number: 20030211582
    Abstract: A human DNA Ligase III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment of disorders associated with a defect in DNA Ligase III. Antagonists against such polypeptides and their use as a therapeutic to destroy unwanted cells are also disclosed. Diagnostic assays to detect mutant DNA Ligase III genes are also disclosed.
    Type: Application
    Filed: June 19, 2003
    Publication date: November 13, 2003
    Inventors: Ying-Fei Wei, Guo-Liang Yu, William A. Haseltine
  • 125 human secreted proteins
    Publication number: 20030211472
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 28, 2001
    Publication date: November 13, 2003
    Inventors: Ping Feng, Steven M. Ruben, Craig A. Rosen, Reinhard Ebner, Henrik S. Olsen, Jian Ni, Ying-Fei Wei, Daniel R. Soppet, Paul A. Moore, Hla Kyaw, David W. LaFleur, Yanggu Shi, Fouad Janat, Gregory A. Endress, Kenneth C. Carter
  • Transforming growth factor alpha hii
    Patent number: 6642006
    Abstract: The present invention discloses transforming growth factor alpha HII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating would healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders, and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
    Type: Grant
    Filed: January 11, 1999
    Date of Patent: November 4, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Ying-Fei Wei, Paul S. Meissner, Jian Ni
  • 83 human secreted proteins
    Publication number: 20030199683
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 30, 2001
    Publication date: October 23, 2003
    Inventors: Steven M. Ruben, Ping Feng, David W. LaFleur, Paul A. Moore, Yanggu Shi, Hla Kyaw, Yi Li, Zhizhen Zeng, Kenneth C. Carter, Gregory A. Endress, Ying-Fei Wei, Ping Fan, Craig A. Rosen
  • Antibodies to secreted protein HCEJQ69
    Patent number: 6627741
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: September 30, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • 207 human secreted proteins
    Publication number: 20030181692
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 22, 2001
    Publication date: September 25, 2003
    Inventors: Jian Ni, Reinhard Ebner, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Yanggu Shi, Kimberly A. Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie L. Fischer, Ann M. Ferrie, Ping Fan, Ping Feng, Gregory A. Endress, Patrick J. Dillon, Kenneth C. Carter, Laurie A. Brewer, Guo-Liang Yu, Zhizhen Zeng, John M. Greene