Abstract: An electronic device and a driving method of a display panel are provided. The electronic device includes a display panel and a driver. The driver is configured to convert a first image signal into a second image signal, output the second image signal to the display panel, and enable the display panel to display an image frame according to the second image signal. Converting the first image signal into the second image signal includes duplicating the first image signal by n times according to a first direction, and simultaneously scanning m adjacent scan lines to simultaneously drive m adjacent pixel units. The first image signal has a first image resolution of A×B, and the second image signal has a second image resolution of m×n×A×B, where m is a positive integer greater than or equal to 2, n is a positive number, and A and B are positive integers.

Abstract: Provided are an earth satellite attitude data fusion system and method, applicable to an earth satellite space environment to estimate attitude data of a satellite. When the earth satellite attitude data fusion system of the present invention is used to perform the earth satellite attitude data fusion method, the first step is to perform a body rates/quaternion attitude data processing operation. Then, the next step is to perform an attitude/rates data fusion processing operation, wherein an attitude data fusion algorithm module receives a first IAE result data from a first EKF, and a second IAE result data from a second EKF, and performs an attitude/rates data fusion algorithm in a subsystem level to evaluate an attitude estimation IAE performance based on the first IAE result data, and the second IAE result data.

Abstract: A plasmid vector for expressing mRNA in vitro, a construction method and an application thereof are provided. The plasmid vector includes a poly(adenyl deoxyribonucleotide) (poly(dA)) fragment formed by more than 30 adenyl deoxyribonucleotides at the 3?-end tail of a gene to be inserted for expression. The plasmid vector for expressing mRNA in vitro in the present invention can express a target protein gene and a poly(A) formed by 60 adenyl ribonucleotides, and the expressed mRNA directly possesses the poly(A) without additional tailing operation. In addition, the mRNA transcribed in vitro shows stronger mRNA stability and higher protein expression ability after being transfected into cells.

Abstract: A delivery system for mRNA nucleic acid drugs, a preparation method and an application thereof are provided. The delivery system includes lipid nanoparticles for loading one or more kinds of mRNA molecules, wherein the lipid nanoparticles are prepared from raw materials including an ionizable cationic lipid, a phospholipid auxiliary lipid, cholesterol, and a polyethylene glycol-derivatized phospholipid. In the mRNA nucleic acid drug targeted intracellular delivery system based on the non-viral carrier of the present invention, the mRNA is concentrated and loaded by the electrostatic interaction between the ionizable cationic lipid and the mRNA. Phospholipid auxiliary lipid component-mediated pH sensitivity and late endosomal escape enable mRNA nucleic acid drugs to be efficiently delivered to target cells and then released into the cytoplasm of the target cells for exerting a pharmacodynamic effect.

Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.

Abstract: A three-dimensional printing apparatus having electrostatic auxiliary, including a printing platform, a feeding device, a nozzle, and a high voltage power supply, is provided. The feeding device and the nozzle are disposed above the printing platform. The nozzle is connected to the feeding device and is located between the feeding device and the printing platform. A distance between the nozzle and the printing platform is less than or equal to 1 cm. The high voltage power supply has an output end electrically connected to the nozzle and a ground end electrically connected to the printing platform.

Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.

Abstract: A microelectromechanical gyroscope system is provided. The system includes a first substrate, a second substrate, and a third substrate. The substrates respectively have a first fixing, a second fixing, and a third fixing surfaces. The system further includes a first sensing, a second sensing and a third sensing module boards respectively fixed to the fixing surfaces. Each sensing module board has several microelectromechanical gyroscopes. A signal processing control board is electrically connected to the first sensing module board, the second sensing module board, and the third sensing module board. Wherein the first substrate, the second substrate, and the third substrate are perpendicular to each other. With the above structure, on each system coordinate axis of the microelectromechanical gyroscope system, at least one gyroscope is aligned with it for data acquisition and measurement. Accordingly, the measurement accuracy of the system is improved.

Abstract: A cell recovery method including the following steps is provided. A cell culture carrier module is provided. The cell culture carrier module includes at least one cell culture carrier. The cell culture carrier is compressed into a first structure. Cell culture is performed by using the cell culture carrier exhibiting the first structure. The cell culture carrier is stretched from the first structure to a second structure. The first structure and the second structure are different structures. Cell recovery is performed by using the cell culture carrier exhibiting the second structure.

Abstract: A tumor neoantigen prediction platform and an application thereof in a neoantigen vaccine development system are provided. The present invention selects 55 HLA-A and HLA-B subtypes with a high proportion of Chinese population from a common database, then establishes a method for constructing cell lines expressing associated HLA subtypes, and subsequently analyzes the resulting HLA subtype cell line binding proteomes by protein mass spectrometry at an attomolar (10?18 molar) level; through very high-precision mass spectrometry of protein profiling presented on the surface of a single cell, the present invention builds a high-frequency HLA-binding polypeptide database for Chinese population; subsequently, a tumor neoantigen prediction algorithm is optimized by a prediction platform including the HLA-binding polypeptide database, thereby significantly improving the tumor neoantigen prediction accuracy.

Abstract: A method and a platform for detecting an immunogenicity of a tumor neoantigen are provided. Specifically, the detection method includes the following steps: culturing human peripheral blood monocytes ex vivo for 13 days, adding an antigenic peptide fragment of human influenza virus and stimulating and activating cytokines, antigenic peptides, and immunoadjuvants during the 13 days, and finally conducting enzyme-linked immunospot (ELISPOT) chromogenic reaction and instrument-based scanning, counting, and analysis to detect the immunogenicity of tumor neoantigen. An application of the detection method and platform in biomedicine is provided. Compared with the prior art, the detection method and platform have advantages and characteristics of a short detection period, high convenience, low consumption of experimental cells, and low detection cost. Therefore, the detection method and platform can be used for ex vivo high-throughput assay for the immunogenicity of the tumor neoantigen.

Abstract: Provided are an earth satellite attitude data fusion system and method, applicable to an earth satellite space environment to estimate attitude data of a satellite. When the earth satellite attitude data fusion system of the present invention is used to perform the earth satellite attitude data fusion method, the first step is to perform a body rates/quaternion attitude data processing operation. Then, the next step is to perform an attitude/rates data fusion processing operation, wherein an attitude data fusion algorithm module receives a first IAE result data from a first EKF, and a second IAE result data from a second EKF, and performs an attitude/rates data fusion algorithm in a subsystem level to evaluate an attitude estimation IAE performance based on the first IAE result data, and the second IAE result data.

Abstract: A cell culture carrier module and a cell culture system having the same are provided. A cell tank and a culture medium module respectively communicate with the carrier module. The carrier module includes a reactor, a first fixer, a second fixer and a plurality of cell culture carriers. The reactor has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the reactor and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. Two ends of each cell culture carrier are fixed to the first fixer and the second fixer, respectively. The cell culture carriers are in an untwisted state or a twisted state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.

Abstract: A video transmission system is disclosed. The video transmission system comprises a multi-drop bus, a first source driving chip, a second source driving chip and a timing controller. The first source driving chip comprises a first source driving circuit and a first terminal circuit. The first terminal circuit is coupled to the multi-drop bus and the first source driving circuit for providing a first terminal resistor. The second source driving chip comprises a second source driving circuit and a second terminal circuit. The second terminal circuit is coupled to the multi-drop bus and the second source driving circuit for providing a second terminal resistor. The timing controller is coupled to the first source driving chip and the second source driving chip via the multi-drop bus.

Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.

Abstract: An eye wearing device is provided, including a body, at least one reservoir and at least one microchannel. The body has a first surface, a second surface, a center, a first outer edge of the first surface and a second outer edge of the second surface. The reservoir is disposed in the body to load the drug. The microchannel is disposed near the first outer edge of the first surface and the second outer edge of the second surface. One end of the microchannel is connected to the reservoir for filling the drug into the reservoir. The other end of the microchannel is an opening facing an edge of the eye wearing device for contacting the cornea and/or the sclera, and the opening is connected to the first outer edge of the first surface and the second outer edge of the second surface.

Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.

Abstract: A high electron mobility transistor (HEMT) device and a manufacturing method thereof are provided. The HEMT device includes a channel layer, a barrier layer, a first gate electrode, a first drain electrode and a first source electrode. The channel layer is disposed on a substrate. A surface of a portion of the channel layer within a first region of the HEMT device includes a polar plane and a non-polar plane. The barrier layer is conformally disposed on the channel layer. The first gate electrode is disposed on the barrier layer, and located within the first region. The first drain electrode and the first source electrode are disposed within the first region, and located at opposite sides of the first gate electrode.

Abstract: A method for manufacturing an electrode including the following steps is provided. A conductive layer is formed on a base material. A radio frequency physical vapor deposition (RF PVD) transition metal compound layer is formed on the conductive layer by using a RF PVD. A sacrificial layer is formed on the RF PVD transition metal compound layer. A planarization process is performed to remove the sacrificial layer and a portion of the RF PVD transition metal compound layer.

Abstract: A high electron mobility transistor (HEMT) device including a substrate, a first channel layer, a second channel layer, a cap layer, a first metal nitride layer, a gate, a source, and a drain is provided. The first channel layer is disposed on the substrate. The second channel layer is disposed on the first channel layer. The cap layer is disposed on the second channel layer and exposes a portion of the second channel layer. The first metal nitride layer is disposed on the cap layer. The gate is disposed on the first metal nitride layer. The width of the first metal nitride layer is greater than or equal to the width of the gate. The source and the drain are disposed on the second channel layer at two sides of the gate.