Abstract: A machine translation system can improve results of machine translations by employing preferred translations, such as human translated phrases. In some implementations, the machine translation system can use the preferred translations as heavily weighted training data when building a machine translation engine. In some implementations, the machine translation system can use the preferred translations as an alternate to a result that would have otherwise been produced by a machine translation engine. While it is infeasible to obtain human translations for all translation phrases, preferred translations can be used for problem phrases for which machine translation engines often produce poor translations. The machine translation system can identify problem phrases by assigning a quality score to each translation in a set of translations.

Abstract: The present invention provides N6-substituted adenosine derivatives and N6-substituted adenine derivatives, manufacturing methods thereof, a pharmaceutical composition comprising the said compounds above, and uses of these compounds in manufacturing medicaments and health-care products for treating insomnia, convulsion, epilepsy, and Parkinson's diseases, and preventing and treating dementia.

Abstract: Systems, methods, and non-transitory computer readable media are configured to receive a uniform resource locator. A time and one or more features associated with the uniform resource locator can be provided to a first machine learning model. A prediction relating to a quantity of views the uniform resource locator achieves by the time can be received from the first machine learning model.

Abstract: An ultrasonic humidifier having stackable and detachable water reservoirs for easy expansion of its water storage capacity. A user can build the ultrasonic humidifier with a number of desired units of the stackable and detachable water reservoirs vertically to suit the usage and to accommodate the space in which the humidifier is used in. Each unit of the stackable and detachable water reservoirs has its own individual floater and draining device to control the replenishment of water to the unit it is attached to. The ultrasonic humidifier having stackable and detachable water reservoirs allows user to refill individual water reservoir unit separately.

Abstract: In one aspect, embodiments of the present disclosure can comprise a non-contact signal detection system for detecting movement associated with a subject. The system can comprise a carrier source configured to generate a first carrier signal in phase coherence with a second carrier signal. Additionally, the system may incorporate a phase-locked loop including noise pre-cancellation system for suppressing the noise associated with a beat signal and a controlled oscillation system. The noise pre-cancellation system can be configured to phase-lock the beat signal to a first reference signal in order to stabilize the phase of the beat signal and pre-cancel the noise associated with the beat signal. The controlled oscillation system can include a propagation pathway on which a transmission signal is phase-modulated with a vibratory signal of the subject. Once acquired, the vibratory signal can have suppressed noise.

Abstract: Technology is discussed herein for identifying comparatively trending topics between groups of posts. Groups of posts can be selected based on parameters such as author age, location, gender, etc., or based on information about content items such as when they were posted or what keywords they contain. Topics, as one or more groups of words, can each be given a rank score for each group based on the topic's frequency within each group. A difference score for selected topics can be computed based on a difference between the rank score for the selected topic in each of the groups. When the difference score for a selected topic is above a specified threshold, that selected topic can be identified as a comparatively trending topic.

Abstract: Methods and apparatus to form fully self-aligned vias are described. First conductive lines are recessed in a first insulating layer on a substrate. A first metal film is formed in the recessed first conductive lines and pillars are formed from the first metal film. Some of the pillars are selectively removed and a second insulating layer is deposited around the remaining pillar. The remaining pillars are removed to form vias in the second insulating layer. A third insulating layer is deposited in the vias and an overburden is formed on the second insulating layer. Portions of the overburden are selectively etched from the second insulating layer to expose the second insulating layer and the filled vias and leaving portions of the third insulating layer on the second insulating layer. The third insulating layer is etched from the filled vias to form a via opening to the first conductive line.

Abstract: Compounds of Formula I: or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein R1, R2, Q1, Q2, and Q3, are described in this disclosure, compositions thereof, and methods and uses thereof.

Abstract: Disclosed are compounds of Formula I(b): or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, wherein Ring A, Ring HD, J, each T, R3, R4, R5, each R7, and m are as described in any of the embodiments described in this disclosure; compositions thereof; and uses thereof.

Abstract: The present invention features compounds having soluble epoxide hydrolase inhibitory activity. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing various medical conditions, such as cardiovascular diseases, respiratory diseases, inflammation, and diabetes.

Abstract: The invention provides, inter alia, compositions useful for, e.g., raising an immune response to HIV-1, and associated methods of raising an immune response to HIV in a mammalian subject. In some embodiments, the compositions are bivalent immunogenic compositions comprising two (or, in some embodiments more than two) human immunodeficiency virus (HIV) clade C envelope gp120 polypeptide antigens, together with a liposome-based adjuvant, such as the adjuvant known as AS01.

Abstract: A series of solid-state lithium ion composite electrolytes is described. The composite materials have lithium ions in an anionic framework wherein the anionic framework has lithium ion vacancies or interstitial Li+ sites. The anionic framework lattice is isostructural to a Laves Mg2Cu lattice and the lithium ion (Li+) conductivity of the solid state lithium ion electrolyte is at least 10?4 S/cm. The activation energy for lithium ion migration in the solid state lithium ion electrolyte is 0.36 sV or less. Composites of specific formulae are provided.

Abstract: A medical device including an array of microneedles and a coating disposed on or within the microneedles and a method of making such a device are disclosed. The coating includes a peptide therapeutic agent and an amino acid. A method of stabilizing a peptide therapeutic agent with an amino acid on an array of microneedles is also disclosed. In some cases, the peptide therapeutic agent and the amino acid either both have a net positive charge or both have a net negative charge. In some cases, the peptide therapeutic agent is histidine.

Abstract: A series of solid-state lithium ion composite electrolytes is described. The composite materials have lithium ions in an anionic framework wherein the anionic framework has lithium ion vacancies or interstitial Li+ sites. The anionic framework lattice is isostructural to a Laves Mg2Cu lattice and the lithium ion (Li+) conductivity of the solid state lithium ion electrolyte is at least 10?4 S/cm. The activation energy for lithium ion migration in the solid state lithium ion electrolyte is 0.36 sV or less. Composites of specific formulae are provided.

Abstract: Disclosed are compounds having a compound of Formula I: or a pharmaceutically acceptable salt, a solvate, a tautomer, an isomer or a deuterated analog thereof, compositions thereof, and uses thereof.

Abstract: Technology is discussed herein for identifying trending actions within a group of posts matching a query. A group of posts can be selected based on specified actions, action targets, or parameters such as author age, location, gender, when the posts were posted or what keywords they contain. Selected posts can be divided into sentences and a dependency structure can be created for each sentence classifying portions of the sentence as actions or action targets. Statistics can be generated for each sentence or post indicating whether it matches the actions, action targets, or other parameters specified in the query. Based on these statistics, additional information can be gathered to respond to questions posed in the query.

Abstract: A medical device, comprising: an array of microneedles, and a coating disposed on the microneedles, wherein the coating comprises: a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination thereof; wherein the local anesthetic is present in an amount of at least 1 wt-% based upon total weight of solids in the coating, and wherein the local anesthetic and dose-extending component are in a non-eutectic weight ratio; a medical device, comprising an array of dissolvable microneedles, the microneedles comprising: a dissolvable matrix material; at least 1 wt-% of a local anesthetic selected from the group consisting of lidocaine, prilocaine, and a combination thereof; and a local anesthetic dose-extending component selected from the group consisting of tetracaine, ropivacaine, bupivacaine, procaine and a combination th

Abstract: Systems and methods for generating or enhancing representations of an interior space using data collected by a device, such as a mobile device, capable of simultaneous localization and mapping. An electronic device, such as a mobile device, can be configured to collect data using a variety of sensors as the device is carried or transported through a space. The collected data can be processed and analyzed to generate geometry data providing a three-dimensional representation of the space and objects in the space in near real time as the device is carried through the space. The geometry data can be used for a variety of purposes, including generating and/or enhancing models and other representations of an interior space, and/or assisting with navigation through the interior space.

Abstract: The present disclosure provides a smart walking recommendation apparatus and a corresponding method, the apparatus includes an information obtaining module configured to obtain destination information and appointed arrival time information, a positioning module configured to obtain a start position of a user, a central processing module configured to calculate a distance from the start position to a destination based on the start position and the destination information, and determine whether to recommended walking based on the distance from the start position to the destination, an empirical speed, and the appointed arrival time information, and an output module configured output a walking recommendation to the user in response to determining to recommend walking.

Abstract: The present disclosure provides an automatic tracking shopping cart. The automatic tracking shopping cart comprises an automatic tracking device. The automatic tracking device is fixed to a body of the shopping cart, operative to control movement of the shopping cart for tracking a target object. The automatic tracking device comprises: an image collection unit configured to collect a color image and a depth image of a field of image; a processing unit configured to identify the target object based on the collected color image and depth image, and determine a motion parameter of the shopping cart based on a position and/or movement of the target object; and a shopping cart driving unit configured to drive the shopping cart to move based on the determined motion parameter. A method for automatically controlling movement of a shopping cart to track a target object is also provided.