Patents by Inventor Yingzhi Bi

Yingzhi Bi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7173042
    Abstract: Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: February 6, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yingzhi Bi, Guixue Yu, David P. Rotella, John E. Macor
  • Publication number: 20050197367
    Abstract: The present invention relates to bicyclic compounds according to formula I, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of androgen receptor-associated conditions, such as age-related diseases, for example sarcopenia, wherein R1, R2, R2? R5, G, n and W are defined herein.
    Type: Application
    Filed: March 2, 2005
    Publication date: September 8, 2005
    Inventors: James Li, Lawrence Hamann, David Augeri, Yingzhi Bi
  • Publication number: 20050187267
    Abstract: Compounds are provided which are useful in the treatment of androgen receptor-associated conditions, such as age-related diseases, which compounds have the structure wherein R1 is hydrogen (H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, arylalkyl or substituted arylalkyl, CO2R4a, CONR4aR4b, and CH2OR4a; R2 is hydrogen (H), OR3, SR3, halo, NHR3, NHCOR4c1, NHCO2R4c1, NHCONR4cR4d and NHSO2R4c; R3 in each functional group is hydrogen (H), alkyl or substituted alkyl, CHF2, CF3 and CON4e; R4, R4a, R4b, R4c, R4c1, R4d, R4e, R4f, R4g, or R4h in each functional group are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, cycloalkyl or substituted cycloalkyl, arylalkyl or substituted arylalkyl, aryl or substituted aryl, or heteroaryl or substituted heteroaryl; R5 and R5? are the same or different and are hydrogen(H), alkyl or substituted alkyl, alkenyl or substituted alkenyl, alkynyl or substituted alkynyl, c
    Type: Application
    Filed: February 1, 2005
    Publication date: August 25, 2005
    Inventors: Lawrence Hamann, Yingzhi Bi, Mark Manfredi, Alexandra Nirschl, James Sutton
  • Publication number: 20050153968
    Abstract: The present invention relates to novel compounds useful in the treatment of androgen receptor associated conditions, such as age-related diseases, pharmaceutical compositions containing at least one of the compounds of the present invention and methods of treating a patient in need of therapy for an androgen receptor associated condition by administering a therapeutically effective amount of at least compound of the present invention.
    Type: Application
    Filed: November 9, 2004
    Publication date: July 14, 2005
    Inventors: Yingzhi Bi, Lawrence Hamann, Mark Manfredi, Ligaya Simpkins
  • Publication number: 20050113358
    Abstract: Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5.
    Type: Application
    Filed: December 21, 2004
    Publication date: May 26, 2005
    Inventors: Yingzhi Bi, Guixue Yu, David Rotella, John Macor
  • Patent number: 6835737
    Abstract: Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: December 28, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yingzhi Bi, Guixue Yu, David P. Rotella, John E. Macor
  • Publication number: 20040181064
    Abstract: The invention provides compounds according to formula I 1
    Type: Application
    Filed: February 17, 2004
    Publication date: September 16, 2004
    Inventors: Chong-Qing Sun, Lawrence Hamann, David Augeri, Yingzhi Bi, Jeffrey Robl, Yan-Ting Huang, Tammy Wang, Alexandra Holubec, Ligaya Simpkins, James C. Sutton, James J. Li
  • Publication number: 20040019063
    Abstract: The invention provides for a pharmaceutical composition capable of modulating the androgen receptor comprising a compound of formula I 1
    Type: Application
    Filed: May 15, 2003
    Publication date: January 29, 2004
    Inventors: Chongqing Sun, Lawrence Hamann, David Augeri, Yingzhi Bi, Jeffrey Robl, Yanting Huang, Tammy Wang, Alexandra Holubec, Ligaya Simpkins
  • Publication number: 20030225128
    Abstract: Compounds of the formula (I) 1
    Type: Application
    Filed: April 14, 2003
    Publication date: December 4, 2003
    Inventors: Yingzhi Bi, Guixue Yu, David P. Rotella, John E. Macor
  • Patent number: 6642244
    Abstract: Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5.
    Type: Grant
    Filed: March 16, 2001
    Date of Patent: November 4, 2003
    Assignee: Bristol-Myers Squibb Co.
    Inventors: John E. Macor, Yingzhi Bi
  • Patent number: 6576644
    Abstract: Compounds of the formula (I) are useful as inhibitors of cGMP PDE especially Type 5.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: June 10, 2003
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Yingzhi Bi, Guixue Yu, David P. Rotella, John E. Macor
  • Publication number: 20020177587
    Abstract: 1
    Type: Application
    Filed: August 20, 2001
    Publication date: November 28, 2002
    Inventors: Yingzhi Bi, Guixue Yu, David P. Rotella, John E. Macor
  • Publication number: 20020133008
    Abstract: Compounds of the formula (I) 1
    Type: Application
    Filed: March 16, 2001
    Publication date: September 19, 2002
    Inventors: John E. Macor, Yingzhi Bi