Abstract: The invention relates to a method for preparing taurine, methyltaurate and methyltaurine by using ethylene oxide, including: preparing taurine by an ethylene oxide process, and obtaining a taurine mother liquor; mixing the taurine mother liquor with methylamine, adding an alkaline catalyst, and carrying out an amination reaction to obtain a reaction solution; evaporating ammonia and methylamine from the reaction solution to obtain a methyltaurate solution; preparing a methyltaurine solution by using the methyltaurate solution; and concentrating and crystallizing the methyltaurine solution to obtain methyltaurine. The method of the invention avoids the problem of recycling a mother liquor in the existing taurine production to reduce the generation possibility of impurities, and meanwhile, can achieve quantitative conversion to methyltaurate and methyltaurine by controlling a molar ratio of raw materials to the catalyst in the reaction.

Abstract: An electronic equipment accessory includes an accessory body and a holder assembly connected to the accessory body. The holder assembly includes a support member and a base. The base is rotatably connected to the accessory body. The support member is rotatable relative to the base between an extended position and a folded position. At the extended position, an included angle is formed between the support member and the base to thereby allow the accessory body to be supported on a support surface. The support member is rotatable relative to the base in one direction and the base is rotatable relative to the accessory body in another direction, thus the support member of the electronic equipment accessory can be adjusted with respect to the accessory body in multiple directions to thereby allow the electronic equipment accessory to support electronic equipment on a support surface at multiple different directions or tilted angles.

Abstract: A cordycepin-based derived compound with an anti-tumor effect, and a structure of the compound is as shown in formula I; a cordycepin derivative and a pharmaceutical composition thereof provided by the invention have a good anti-tumor proliferation effect; compared with a parent drug, the cordycepin derivative has better affinity to cell membranes, so that a half-life period of in-vivo metabolism of the drug is longer, and in-vivo remaining time of the drug is longer; compared with other nucleoside anti-tumor drugs, the cordycepin derivative and the pharmaceutical composition thereof provided by the invention have wider types and action ranges of tumors, have excellent inhibition effects on a gastric cancer, a pancreatic cancer, a liver cancer, a small cell lung cancer, a colorectal cancer, melanoma, an ovarian cancer and the like, and have lower side effects and better curative effects.

Abstract: The present invention provides a lipid nanoparticle comprising a fentanyl hapten, and a T helper peptide and/or an adjuvant, wherein the fentanyl hapten is conjugated to the outer surface of the lipid nanoparticle, and wherein the T helper peptide and/or the adjuvant is/are encapsulated within the lipid nanoparticle. The invention further provides a pharmaceutical composition comprising the lipid nanoparticle and uses thereof for inducing an immune response against fentanyl and the prevention or treatment of a fentanyl abuse disorder or a fentanyl addiction or a fentanyl overdose in a subject. Further provided herein is a method for preparing the lipid nanoparticle of the invention.

Abstract: Embodiments of the present disclosure relate to the field of charging piles, and disclose a charging gun returning control method and device for a charging pile, a charging pile, and a medium, wherein the method includes: acquiring a signal intensity change generated between a charging gun and a gun seat when the charging pile is in a non-charging state; determining that a current operation is a gun unplugging operation when it is detected that the signal intensity change is less than a gun unplugging change threshold; and determining that the current operation is a gun plugging operation when it is detected that the signal intensity change is greater than a gun plugging change threshold; where the gun unplugging change threshold and the gun plugging change threshold are mutually opposite numbers.

Abstract: A hierarchical control system for torque distribution of hub motor-driven electric vehicles constructs a hierarchical controller with upper and lower layers. An upper layer torque distribution controller's drive torque distribution control strategy is determined through a fuzzy control module. A lower layer torque distribution controller receives the torque, yaw velocity, and side-slip angle from the upper layer torque distribution controller and performs drive torque distribution control based on the motor efficiency map or tire slip rate by using the torque, yaw velocity, side-slip angle and actual values of vehicle feedback to obtain a generalized torque output to a wheel hub motor model for calculating to obtain a target torque and inputting it into a 7-degree-of-freedom vehicle model. The 7-degree-of-freedom vehicle model feeds back vehicle states to the upper layer torque distribution controller to form a closed-loop control, achieving energy-saving control and improving handling stability and safety.

Abstract: A method includes: controlling a prefunded account of an issuer system by a transaction processing system; receiving first transaction requests associated with first transactions initiated by first payment devices issued by the issuer system; for each first transaction: determining that the issuer system issued a corresponding first payment device; determining an accumulated authorization amount; determining that the accumulated authorization amount does not satisfy a threshold based on the prefunded amount; and generating and communicating an authorization request associated with the corresponding first transaction to the issuer system; receiving a second transaction request associated with a second transaction initiated by a second payment device issued by the issuer system; in response to receiving the second transaction request, determining that the issuer system issued the second payment device; determining an updated accumulated authorization amount; determining that the updated accumulated authorizatio

Abstract: A rehabilitation device is adapted for wrist rehabilitation, and includes two magnetic actuators and a movable frame unit. Each of the magnetic actuator includes a motor, a rotating shaft, a rotating member, and two magnetic coupling subunits that are respectively connected to the motor and the rotating shaft. Each of the magnetic coupling subunits includes a magnetic ring that has a plurality of N pole portions and a plurality of S pole portions alternately arranged about a center of the magnetic ring. For each of the magnetic actuators, when one of the magnetic coupling subunits that is connected to the motor is driven by the motor to rotate, the other one of the magnetic coupling subunits that is connected to the rotating shaft is urged to rotate by attraction between the magnetic rings of the magnetic coupling subunits such that the rotating shaft and the rotating member rotate.

Abstract: A display panel and a manufacturing method thereof are provided. The display panel includes a substrate, a gate layer including a plurality of gate units disposed over the substrate, a first insulating layer disposed on the gate layer, and a metal shielding layer disposed on the first insulating layer. The metal shielding layer includes metal shielding units corresponding to the gate units. By setting the metal shielding layer, an electric shielding principle is used to reduce an influence of an alternating current signal between the gate units and improve display performance.

Abstract: A composite ozone catalyst, a preparation method and use thereof. The composite ozone catalyst of the present invention includes a co-carrier mixed with biochar and a silica-alumina-based material, and a metal element and a nitrogen element supported on the co-carrier. The preparation method includes mixing the biochar and the silica-alumina-based material powder and then placing the same in a metal precursor solution for impregnation, adding a polyvinyl pyrrolidone solution to the impregnated material, wet granulating to form a spherical material, and calcining the spherical material to obtain the composite ozone catalyst. The composite ozone catalyst has low production cost, simple preparation processes, good catalytic performance, and strong stability, which can meet the high-efficiency and low-consumption requirements of ozone catalytic oxidation in the advanced treatment of industrial wastewater.

Abstract: Provided is a method for preparing a hard carbon anode of a lithium/sodium ion battery by biochar, which includes the following steps: S1 biochar pretreatment, S2, preparing a precursor material and S3 pyrolysis carbonization, by a modification of the biochar, setting carbonization temperature and carbonization time, and controlling a cooling rate, so that the obtained biochar generates amorphous carbon after carbonization with low graphitization degree, few surface defects, larger charge-discharge specific capacity, and stable performance in the cycle charging and discharging process; at the same time, the process of the application is relatively simple, and a special complex process is reduced; the present method is suitable for a large-scale industrial production without special adjustment or control of a morphology; and the product performance is relatively good and thus has certain competitive advantages.

Abstract: Disclosed are methods of isolating T cells having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation, the method comprising: identifying one or more genes in the nucleic acid of a cancer cell of a patient, each gene containing a cancer-specific mutation that encodes a mutated amino acid sequence; inducing autologous APCs of the patient to present the mutated amino acid sequence; co-culturing autologous T cells of the patient with the autologous APCs that present the mutated amino acid sequence; and selecting the autologous T cells. Also disclosed are related methods of preparing a population of cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer.

Abstract: The present disclosure provides a liquid loading device for loading liquid into a product. The product includes a cavity and a liquid inlet communicated with the cavity. The liquid loading device includes a loading module to load liquid into the cavity through the liquid inlet. A sensor senses a pressure in the cavity and generates at least one pressure value. A controller is coupled to the sensor and the loading module, and controls the loading module to operate based on related data. In addition, the present disclosure also provides a liquid loading method.

Abstract: Disclosed are an automobile diagnosis device, system and method. The automobile diagnosis device includes: a diagnosis protocol transceiver configured to fault code data of an automobile to be diagnosed; a communication module; a master controller electrically connected to the diagnosis protocol transceiver and the communication module; a multimeter circuit electrically connected to the master controller and configured to send multimeter data to the master controller; an oscilloscope circuit electrically connected to the communication module and configured to send oscilloscope data to the host computer by means of the communication module; a signal generating circuit electrically connected to the master controller and configured to generate an analog waveform signal in response to a driving signal of the master controller. The adaptability of the automobile diagnosis device is improved.

Abstract: A method of multi-material 3D printing is performed by an apparatus comprising at least one printhead device; a build platform; a light source; and a computing unit comprising a non-transitory computer-readable medium encoded with program instructions for controlling the at least one printhead device; the build platform; and the light source to perform the method of multi-material 3D printing. In various embodiments, each printhead device comprises a coating section, a curing section, a cleaning section, and optionally, a post-curing section. Each printhead device is configured to perform each of these steps, with the multiple printheads engaged in fabricating a multi-material part layer-by-layer.

Abstract: Disclosed are a method for generating a high-precision road map, a high-precision road map generation device, equipment and a storage medium. The method includes: based on a constant temperature control system, collecting a plurality of road information to be processed by different sensors, so that the different sensors can all operate at a suitable temperature and are not affected by the environment; performing feature extraction on the plurality of the road information to be processed, and obtaining road feature information; and connecting a mileage meter by a vehicle controller area network port or a related domain controller to obtain mileage information of the vehicle and posture control information of the vehicle, and predicting the posture of the vehicle to provide auxiliary information for an inertial system, and finally generating a high-precision road map according to the road feature information, vehicle body posture control information of a vehicle and mileage information.

Abstract: Disclosed herein are methods of regional gene-therapy with growth-factor transduced cells, in bone graft scenarios. In embodiments, the methods comprise use of 3D printed scaffolds.

Abstract: A mobile phone transfers a picture to the tablet. After the mobile phone detects a sliding operation of a finger of a user, the tablet displays, on a screen, an animation in which the picture is transferred in a sliding direction of the finger of the user.

Abstract: A multi-chip package including a first integrated circuit and a second integrated circuit. The first integrated circuit includes a first side having a first conductive layer, a second side having a second conductive layer, and an edge, the first conductive layer coupled to the second conductive layer at a location adjacent to the edge. The second integrated circuit is coupled to the second conductive layer of the first integrated circuit.