Patents by Inventor Yong Hua Zhu

Yong Hua Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9364578
    Abstract: This invention relates to deployable hemostatic materials comprising chitosan fibers. The hemostatic materials are suitable for use in sealing or controlling active bleeding from artery and vein lacerations and punctures, and for controlling oozing from tissue.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: June 14, 2016
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Chang Zheng Yang, Wolff M. Kirsch
  • Patent number: 9364205
    Abstract: A method and apparatus for closing a vascular wound includes an apparatus that can be threaded over a guidewire into place at or adjacent the wound. The apparatus includes a chamber that encloses a hemostatic material therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: June 14, 2016
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 9320505
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. The vascular puncture wound is sealed by natural blood clot formation.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: April 26, 2016
    Assignee: Loma Linda University
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Publication number: 20160058904
    Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.
    Type: Application
    Filed: November 5, 2015
    Publication date: March 3, 2016
    Inventors: Wolff M. Kirsch, Yong Hua Zhu, Samuel Hudson
  • Publication number: 20160030025
    Abstract: A method and apparatus for closing a vascular wound includes an apparatus that can be threaded over a guidewire into place at or adjacent the wound. The apparatus includes a chamber that encloses a hemostatic material therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. A blocking member distal of the hemostatic material functions as a barrier to prevent the hemostatic material from entering the wound. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.
    Type: Application
    Filed: October 15, 2015
    Publication date: February 4, 2016
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Publication number: 20150320422
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.
    Type: Application
    Filed: July 20, 2015
    Publication date: November 12, 2015
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 9179902
    Abstract: A method and apparatus for closing a vascular wound includes an apparatus that can be threaded over a guidewire into place at or adjacent the wound. The apparatus includes a chamber that encloses a hemostatic material therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. A blocking member distal of the hemostatic material functions as a barrier to prevent the hemostatic material from entering the wound. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: November 10, 2015
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 9101731
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.
    Type: Grant
    Filed: June 20, 2013
    Date of Patent: August 11, 2015
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 9027560
    Abstract: A breathing gas delivery system and method provides a flow of breathing gas to a patient. The gas flow is purposely interrupted for the patient's exhale phase in order to minimize irritation and injury to nasal tissues due to constant, uninterrupted flows. Embodiments include an oscillating ball valve that interrupts oxygen supply during the patient's exhale phase, cannula tips that are shaped to minimize trauma, and a sleep apnea treatment system that interrupts breathing gas supply during the patient's exhale phase.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: May 12, 2015
    Assignees: Loma Linda University, Faculty Physicians and Surgeons of LLUSM
    Inventors: Albert W. Farnsworth, Wolff M. Kirsch, Yong Hua Zhu
  • Publication number: 20150086419
    Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.
    Type: Application
    Filed: December 4, 2014
    Publication date: March 26, 2015
    Inventors: Wolff M. Kirsch, Yong Hua Zhu, Samuel Hudson
  • Publication number: 20140180335
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. The vascular puncture wound is sealed by natural blood clot formation.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Publication number: 20140178446
    Abstract: This invention relates to deployable hemostatic materials comprising chitosan fibers. The hemostatic materials are suitable for use in sealing or controlling active bleeding from artery and vein lacerations and punctures, and for controlling oozing from tissue.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Chang Zheng Yang, Wolff M. Kirsch
  • Patent number: 8703176
    Abstract: This invention relates to deployable hemostatic materials comprising chitosan fibers. The hemostatic materials are suitable for use in sealing or controlling active bleeding from artery and vein lacerations and punctures, and for controlling oozing from tissue.
    Type: Grant
    Filed: February 18, 2005
    Date of Patent: April 22, 2014
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Chang Zheng Yang, Wolff M. Kirsch
  • Patent number: 8702750
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. The vascular puncture wound is sealed by natural blood clot formation.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: April 22, 2014
    Assignee: Loma Linda University
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Publication number: 20140093421
    Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.
    Type: Application
    Filed: December 4, 2013
    Publication date: April 3, 2014
    Applicant: Loma Linda University Medical Center
    Inventors: Wolff M. Kirsch, Yong Hua Zhu, Samuel Hudson
  • Publication number: 20140058443
    Abstract: A method and apparatus for closing a vascular wound includes an apparatus that can be threaded over a guidewire into place at or adjacent the wound. The apparatus includes a chamber that encloses a hemostatic material therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. A blocking member distal of the hemostatic material functions as a barrier to prevent the hemostatic material from entering the wound. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.
    Type: Application
    Filed: October 31, 2013
    Publication date: February 27, 2014
    Applicant: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 8623274
    Abstract: A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile. A single or multiple such treatments may be employed. For example, the chitosan textile may be irradiated under nitrogen using ?-irradiation, treated under a nitrogen plasma, or both.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: January 7, 2014
    Assignee: Loma Linda University Medical Center
    Inventors: Wolff M. Kirsch, Yong Hua Zhu, Samuel Hudson
  • Patent number: 8617253
    Abstract: A method and apparatus for closing a vascular wound includes an apparatus that can be threaded over a guidewire into place at or adjacent the wound. The apparatus includes a chamber that encloses a hemostatic material therein. When the apparatus is positioned adjacent the wound as desired, the hemostatic material is deployed from the chamber. A blocking member distal of the hemostatic material functions as a barrier to prevent the hemostatic material from entering the wound. Blood contacts the hemostatic material, and blood clotting preferably is facilitated by a hemostatic agent within the material. Thus, the vascular puncture wound is sealed by blood clot formation.
    Type: Grant
    Filed: December 1, 2011
    Date of Patent: December 31, 2013
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Publication number: 20130281785
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.
    Type: Application
    Filed: June 20, 2013
    Publication date: October 24, 2013
    Inventors: Yong Hua Zhu, Wolff M. Kirsch
  • Patent number: 8491628
    Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: July 23, 2013
    Assignee: Loma Linda University Medical Center
    Inventors: Yong Hua Zhu, Wolff M Kirsch