Abstract: A patch applicator has an elongate body with an inner lumen and an outer lumen arranged concentrically. A patch is also provided. In operation, a source of vacuum draws a vacuum through the inner lumen. The inner lumen is applied to a patch to releasably hold the patch. The patch is advanced within the patient until it is placed on top of and over a wound in tissue. Flowable adhesive is injected through the outer lumen onto the patch and tissue surrounding the patch. The patch applicator holds the patch in place, allowing the adhesive to at least partially set. The applicator is then removed from the patch. Thus, an adhesive patch is attached to close an opening in tissue.

Abstract: An improved device and method are provided for securing the urethra to the bladder in surgery. A trocar is provided for insertion into the urethra. The trocar is removably secured to the urethra for advancement of the proximal end toward the bladder. A sheath is inserted and secured to the bladder in order to assist in the advance of the bladder toward the urethra. The improved system permits medical personnel to clamp the urethra and bladder without the need for insertion of time consuming and laborious sutures. A method of securing the urethra and bladder using the disclosed apparatus is also provided.

Abstract: The present invention provides medicament-containing cyanoacrylate adhesive formulations for sealing wounds.

Abstract: An apparatus for facilitating the locating, everting, and closing an opening in a blood vessel. The apparatus can include a closure instrument having an elongated member defining a longitudinal axis and proximal and distal ends. The elongated member has a vacuum lumen extending at least a portion of the length thereof for conveying a vacuum and terminating in a vacuum port adjacent the distal end of the elongated member. The distal end of the elongated member is dimensioned to be positioned proximal a vessel opening in a blood vessel whereby vessel edge portions defining the vessel opening are at least drawn toward the vacuum port in response to a vacuum conveyed through the vacuum lumen. At least one surgical clip is mounted adjacent the distal end of the elongated member and is adapted to be formed to an at least partially formed condition thereof.

Abstract: An improved device and method are provided for securing the urethra to the bladder in surgery.

Abstract: A triceps for anastomosis, the triceps having two outer legs on opposing sides of a middle leg. A latch is located on one outer leg and the middle leg to hold the respective legs in a clamped position. An alignment post extends through the middle leg and cooperates with holes in the outer legs to allow the post to enter the holes and ensure alignment of the legs in use. The post has an enlarged base portion that does not pass through the hole and thereby limits movement of the outer legs relative to the inner legs and thereby limits clamping pressure at the free ends of the legs. The free ends of the legs have various cooperating shapes to facilitate everting and aligning tubular vessels and body tissue for anastomosis.

Abstract: An improved device and method are provided for securing the urethra to the bladder in surgery. A trocar is provided for insertion into the urethra. The trocar is removably secured to the urethra for advancement of the proximal end toward the bladder. A sheath is inserted and secured to the bladder in order to assist in the advance of the bladder toward the urethra. The improved system permits medical personnel to clamp the urethra and bladder without the need for insertion of time consuming and laborious sutures. A method of securing the urethra and bladder using the disclosed apparatus is also provided.

Abstract: A system which facilitates the closure of puncture wounds in the vasculature of a patient by helping locate and isolate the site of the puncture wound in the patient. A tube or catheter having an indicator hole for aspirating blood assists in locating the exact site of the wound. A retractor moves the surrounding tissue laterally forming an access path to the wound, and acts as a guide for the wound closure device. The retractor and accessories are preferably used in combination with a surgical clip applicator which delivers clips to the site of the wound, but can also be used with other methods of wound closure such as suturing and stapling.

Abstract: A method and apparatus for closing a vascular wound includes a guidewire and/or other surgical implement extending from the wound. A hemostatic material is advanced over the surgical implement and into contact with an area of the blood vessel surrounding the wound. The surgical implement is removed. Blood soaks the hemostatic material, and blood clotting is facilitated by the hemostatic agent within the material. A sealing layer of adhesive can be applied to the hemostatic material, confining the blood flow to the material. Thus, the vascular puncture wound is sealed by natural blood clot formation.

Abstract: A patch applicator has an elongate body with an inner lumen and an outer lumen arranged concentrically. First and second connectors are provided and correspond to the inner and outer lumens, respectively. A patch is also provided. In operation, a source of vacuum is connected to the first connector and draws a vacuum through the inner lumen. The inner lumen is then applied to a patch to releasably hold the patch. The patch is advanced within the patient until it is placed on top of and over a wound in tissue. The source of vacuum is then transferred to the second connector and pulls a vacuum through the outer lumen to clear bodily fluid from a field around the wound. After the field is cleared, the source of vacuum is removed and replaced by a source of flowable adhesive. Adhesive is injected through the outer lumen onto the patch and tissue surrounding the patch. The patch applicator holds the patch in place, allowing the adhesive to set.

Abstract: An apparatus for facilitating the locating, everting, and closing of an opening in a blood vessel. The apparatus can include a closure instrument having an elongated member defining a longitudinal axis and proximal and distal ends. The elongated member has a vacuum lumen extending at least a portion of the length thereof for conveying a vacuum and terminating in a vacuum port adjacent the distal end of the elongated member. The distal end of the elongated member is dimensioned to be positioned proximal a vessel opening in a blood vessel whereby vessel edge portions defining the vessel opening are at least partially drawn toward the vacuum port in response to a vacuum conveyed through the vacuum lumen. At least one surgical clip is mounted adjacent the distal end of the elongated member and is adapted to be formed to an at least partially formed condition thereof.

Abstract: An apparatus for facilitating the locating, everting, and closing of an opening in a blood vessel. The apparatus can include a closure instrument having an elongated member defining a longitudinal axis and proximal and distal ends. The elongated member has a vacuum lumen extending at least a portion of the length thereof for conveying a vacuum and terminating in a vacuum port adjacent the distal end of the elongated member. The distal end of the elongated member is dimensioned to be positioned proximal a vessel opening in a blood vessel whereby vessel edge portions defining the vessel opening are at least partially drawn toward the vacuum port in response to a vacuum conveyed through the vacuum lumen. At least one surgical clip is mounted adjacent the distal end of the elongated member and is adapted to be formed to an at least partially formed condition thereof.

Abstract: A medical anastomosis sling for use in the repair or regeneration of nerves. Nerve ends are placed in a breathable semiporous membrane having sets of elongate and wide tabs which are secured and sealed around the ends via circumferential fasteners and surgical clips for securing and sealing the sling in position without the necessity of suturing the device for optimal anastomosis.

Abstract: A device which facilitates the closure of puncture wounds in the vasculature of a patient is used in conjunction with a guidewire, and helps locate and isolate the site of the puncture wound in the patient. The retractor moves the surrounding tissue laterally when positioned in the patient, and acts as a guide for the physician in locating the exact site of the wound. A double-sleeved balloon can be used in conjunction with the retractor to move the tissues laterally and form a tunnel from the surface of the patient's body to the puncture site. The retractor is preferably used in combination with a surgical clip applicator which delivers clips to the site of the wound, but can also be used with other methods of wound closure such as suturing and stapling.

Abstract: A tissue everting apparatus includes at least one elongated frame, at least one actuator slidably mounted to the frame and longitudinally movable between proximal and distal positions, a tissue everting bulbous tip, and at least two prongs which are laterally movable between open and closed positions. The bulbous tissue everting tip is positioned, for example, in the lumen of a vascular segment to evert the edge and the prong is closed to capture the everted edge of the vascular segment. The edge of a second vascular segment is everted and captured in a similar manner with the edges being brought together to form a flange-like structure to which one or more surgical clips may be applied to fasten the segments together.

Abstract: A needle for everting body tissue is a linear member having a back portion, an arcuate tissue penetrating portion, and a generally U-shaped tissue everting portion therebetween. The U-shaped tissue everting portion includes a base and first and second tissue abutment arms, the back portion preferably being collinear with the first arm and oriented at an angle with respect to the base. The needle can be incorporated into an instrument for use in endoscopic procedures. In such instruments the needle can be attached in a fixed position with respect to the instrument, or retractable within a tubular sleeve.

Abstract: A dental apparatus, including an instrument having an optical fiber for delivering UV light, an optical viewing fiber and an irregular surface located on the exterior surface at the distal end of the instrument to provide tactile feedback. The instrument preferably additionally comprises an irrigation channel, a suction channel, and abrasives on the distal end of the device. Other aspects of the invention include inventive dental procedures, facilitated by the apparatus, including the cleaning of teeth, periodontic and endodontic procedures, and bleaching discolored teeth.

Abstract: A membrane endoscopic retractor is disclosed for retracting organs and tissue inside the body using only small tools extending through short incisions in the body. The membrane retractor generally comprises a membrane for supporting tissue and organs and two or more probes for supporting the membrane. The probes are endoscopic devices which allow the user to place and manipulate the membrane inside a body by stretching and supporting the membrane between and along various points. The membrane is rollably arranged inside a housing on one probe so as to easily be inserted into the body and then extended therefrom by a second probe. A third probe may be used to provide additional support to the membrane between the first and second probes. The entire retraction procedure inside the body is manipulatable from control ends of the probes which are located outside of the body.