Abstract: Provided are a compound represented by formula (III) or pharmaceutically acceptable salts, solvates, active metabolites, polymorphs, esters, tautomers or prodrugs thereof, pharmaceutical compositions containing the compound represented by formula (III), and the application of the pharmaceutical compositions as selective inreversible inhibitor of Bruton's tyrosine kinase for the prevention and treatment of inflammation, autoimmune diseases (such as rheumatoid arthritis) associated with aberrant B cell proliferation and cancers.

Abstract: A protective cover for a portable electronic device, which is configured for supporting the device and for storing an earphone and cable, includes a casing body, a winding portion, a limiting plate, and a support plate. The device is received in a receiving portion in the casing body and the winding portion protrudes out of one side of the casing body spaced apart from the receiving portion, the winding portion being able to accept the cable of the earphone wound onto it. The limiting plate covers one side of the winding portion spaced apart from the casing body and defining an opening. The support plate covers the opening of the limiting plate and is rotatably coupled to the limiting plate. A ring-shaped accommodating space is defined between the limiting plate and the casing body for receiving the cable of the earphone wound onto the winding portion.

Abstract: The present disclosure describes a dockbar implementation method, device and system, which belong to the field of communications. The method includes: acquiring an interface operation instruction for an application program inside a dockbar; generating a dockbar interface refresh data according to the interface operation instruction; and refreshing an interface of the dockbar according to the dockbar interface refresh data. The device includes an application layer and a logic layer. The present disclosure can realize the dynamicity of the dockbar and improve the flexibility of the dockbar.

Abstract: An electronic device enclosure includes a chassis, a bracket, a shaft and a supporting member. The bracket is rotatably connected to the chassis through the shaft. The supporting member is sheathed with the shaft. Two opposite ends of the supporting member are respectively fixed to the chassis and the bracket. When the bracket rotates in a first direction relative to the chassis, the supporting member is elastically deformable to support the bracket preventing the bracket from rotating towards a second direction relative to the chassis. And the first direction is opposite to the second direction.

Abstract: The invention provides a compound represented by formula (I) which may modulate a kinase, and a pharmaceutical composition thereof, as well as the method for preventing or treating a protein kinase mediated disease or condition.

Abstract: A nonvolatile memory is organized into blocks as erase units and physical pages as read/write units. A host addresses data by logical pages, which are storable in corresponding physical pages. Groups of logical pages may be further aggregated into logical groups as addressing units. The memory writes host data in either first or second write streams, writing to respective blocks either logical-group by logical-group or logical-page by logical-page in order to reduce the size of logical-to-physical-address maps that are cached in a controller random-access memory (RAM). A group-level map may be used to track logical groups. A page-level map may be used to track logical pages. Only one block at a time needs be open in the second stream to accept logical pages from multiple logical groups that are active. Garbage collection is performed on the blocks from each write stream independently without data copying between the two streams.

Abstract: Systems and methods for improving NAND flash memory yields by identifying memory blocks with benign word line defects. Memory blocks including word line defects may be classified as incomplete memory blocks and may be used for storing data fragments. A data fragment may correspond with data written into memory cells associated with one or more contiguous word lines within a memory block that does not include a bad word line. In some cases, firmware associated with a NAND flash memory device may identify one or more data fragments based on the location of bad word lines within a memory block. A word line defect may be considered a benign defect if the defect does not prevent memory cells connected to other word lines within a memory block from being programmed and/or read reliably.

Abstract: An implementation of a system disclosed herein provides an apparatus, comprising a system on chip, wherein the system on chip is configured to receive a sleep command from a host and in response to the sleep command, calculate a primary checksum of a block of data from a low latency memory such as a tightly coupled memory (TCM), copy the primary checksum and the block of data into a volatile storage media, preserve interface variables of the system on chip in the volatile storage media, operate the volatile storage media in a self-refresh mode, and shut down power to other components on the system on chip.

Abstract: The present invention relates to a quinazoline derivative shown in formula (I) and a preparation method therefor, a pharmaceutical composition comprising the compound shown in formula (I), and an application of the compound in preparing drugs for curing and preventing tumors.

Abstract: The invention provides novel ethylene derivatives represented by Formula I, which may be used as selective estrogen receptor modulators (SERMs) and useful in the prophylaxis and/or treatment of estrogen-dependent conditions or conditions.

Abstract: Disclosed are a 2-aminopyridine derivative having protein kinase inhibition activity, preparation method and pharmaceutical composition thereof. Also disclosed are uses of the compound and the pharmaceutical composition thereof in the preparation of drugs for treating and/or preventing protein kinase-related diseases.

Abstract: Various embodiments may relate to a circuit device and an electronic apparatus. The circuit device may include a main circuit unit, an energy store and output unit and a valley detection unit. The main circuit unit transfers energy to the energy store and output unit according to a detected voltage of the valley detection unit. Furthermore, the circuit device described above also includes a malfunction processing unit for preventing the main circuit unit from transferring energy to the energy store and output unit by adjusting the detected voltage of the valley detection unit in the case that the energy store and output unit has an output malfunction. Hereby, elements in the circuit device may be prevented from being damaged by the output malfunction. Moreover, the circuit device has a simple structure and is cost effective.

Abstract: A storage module and method for configuring the storage module with memory operation parameters are provided. In one embodiment, a storage module is provided comprising a memory and a controller. The controller is configured to receive a selection of one of a plurality of sets of memory operation parameters stored in the storage module and perform at least one of a read operation and a write operation on the memory in accordance with the selected set of memory operation parameters.

Abstract: The invention provides novel poly-substituted 5-membered heterocyclic compounds represented by Formula (IV), or a pharmaceutically acceptable salt, solvate, metabolites, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as selective irreversible bruton's tyrosine kinase (Btk) inhibitors and is further useful to treat inflammatory, auto immune diseases associated with aberrant B-cell proliferation such as RA (rheumatoid arthritis) and cancers. This invention also provided the preparation of a medicament using of Formula (IV), and methods of preventing or treating diseases associated with excessive Btk activity in mammals, especially humans.

Abstract: A nonvolatile memory is organized into blocks as erase units and physical pages as read/write units. A host addresses data by logical pages, which are storable in corresponding physical pages. Groups of logical pages are further aggregated into ogical groups as addressing units. The memory writes host data in either first or second write streams, writing to respective blocks either logical-group by logical-group or logical-page by logical-page in order to reduce the size of logical-to-physical-address maps that are cached in a controller RAM. Only one block at a time needs be open in the second stream to accept logical pages from multiple logical groups that are active. Garbage collection is performed on the blocks from each write stream independently without data copying between the two streams.

Abstract: Provided are method, device and computer storage medium for controlling desktop. The method includes: creating a first interface as a sub-window of a desktop container according to a creating instruction; and embedding the first interface created as the sub-window into the desktop container. The device includes: a sub-window creating module, configured to create a first interface as the sub-window of a desktop container according to a creating instruction; and an interface processing module, configured to embed the first interface created as the sub-window into the desktop container and display full-screen. The present disclosure is adopted to simplify operations among multiple interfaces in the desktop.

Abstract: A positioning system having a flat base comprising (i) a X-axis assembly having a X-axis linear actuator means arranged orthogonal to the Y-axis; (ii) a Y-axis assembly having a pair of Y-axis linear actuator means mounted onto the flat base forming a H-configuration; (iii) a Z-axis assembly having an aerostatic bearing mechanism that floats on thin film of externally pressurized air on top of the flat base; and a ?-axis actuator anchored from the X-axis to drive the Z-axis assembly which carries a workpiece, wherein the Z-axis assembly is rotated with the rotary axis for the ?-axis perpendicular to the flat base.

Abstract: Described are a method and a system for implementing function extension of an open platform. In the system, services that can be provided by an open platform are encapsulated and an operation interface is provided, so that plug-ins uniformly inherit the operation interface and transmit control parameters through the interface into a service entry to obtain the services. Therefore, the open platform has a simple framework and low coupling degree. Since the plug-ins are uniformly managed by a plug-in manager, the manageability and dynamic extensibility of the open platform are enhanced.

Abstract: The invention provides novel ethylene derivatives represented by Formula I, which may be used as selective estrogen receptor modulators (SERMs) and useful in the prophylaxis and/or treatment of estrogen-dependent conditions or conditions.

Abstract: Methods for improving NAND flash memory yields by identifying memory blocks with benign word line defects are described. Memory blocks including word line defects may be classified as incomplete memory blocks and may be used for storing data fragments. A data fragment may correspond with data written into memory cells associated with one or more contiguous word lines within a memory block that does not include a bad word line. In some cases, firmware associated with a NAND flash memory device may identify one or more data fragments based on the location of bad word lines within a memory block. A word line defect may be considered a benign defect if the defect does not prevent memory cells connected to other word lines within a memory block from being programmed and/or read reliably.