Abstract: A nucleic acid extraction method includes the following steps. Firstly, a mixture of a sample and a lysis buffer is provided. The pH of the lysis buffer is lower than 7. Then, the mixture of the sample and the lysis buffer is transferred to a nucleic acid catching chamber containing chitosan coating material, so that nucleic acid of the sample is bound to the chitosan coating material. Then, the chitosan coating material is washed with at least one wash buffer, thereby removing residual protein and cell debris. Then, the chitosan coating material is eluted with an elution buffer while heating the chitosan coating material, so that the nucleic acid is separated from the chitosan coating material. The pH of the elution buffer is higher than 7.

Abstract: A method, and associated computer system and computer program product. A change of runtime code is detected by one or more processors of the computer system. The change is detected in a debugging session on a first machine. The runtime code is obtained from source code that is developed on a second machine that is different from the first machine. In response to the change being detected, a portion of the source code associated with the detected change is determined, by the one or more processors, based on a profile. The profile indicates a mapping between the source code and the runtime code. The portion of the source code is caused, by the one or more processors, to be updated based on the detected change in the runtime code.

Abstract: The invention relates to the technical field of data hiding, in particular to a data hiding method and a data hiding system. An image is used as a data carrier; after secret data is converted into a bit sequence by a sending end, the values of each bit in the bit sequence are hidden in the image; the image hidden with the secret data is obtained and is sent to a receiving end; and the receiving end can extract the hidden secret data from the image according to a corresponding secret key. During data hiding, each square image block can hide two-bit data through inverse number odd-even properties of a pixel gray value sequence of two diagonal lines of each square image block, so that the volume of data hidden in the image is twice of the number of the image blocks split by the image.

Abstract: A time information coding method is provided, to solve the problem of coded values low calculation efficiency, which is resulted by adopting the existing time information coding schemes. The method comprises: determining time information to be coded; coding the time information to be coded to a first integer with a specified number of bits under a first time scale; coding the first integer into a second integer with a specified number of bits under a second time scale, the second integer being as a coded value under the second time scale of the time information to be coded. A time information coding device, a searching method for coded values, a decoding method and device are also provided.

Abstract: The invention provides a method, apparatus, device and storage medium for predicting a protein binding site. The method comprises the steps of: receiving a protein sequence to be predicted, dividing the protein sequence by using a preset sliding window and sliding step to obtain a plurality of amino acid sub-sequences, building word vectors for the protein sequence according to the amino acid sub-sequences, extracting document features from word elements, building document feature vectors for the protein sequence according to the extracted document features, extracting protein chain biological features from the amino acid sub-sequences, building biological feature vectors for the protein sequence according to the extracted biological features, classifying the amino acid sub-sequences expressed with the document feature vectors and the biological feature vectors by using a preset amino acid residue classification model to obtain amino acid residue types for the protein sequence.

Abstract: The disclosure discloses an array substrate, a method for fabricating the same, a liquid crystal display panel, and a display device, where the array substrate includes: a base substrate; a convex component located on the base substrate; a reflection layer overlying the convex component; a thin film transistor located above a film layer at which the reflection layer is located; a pixel electrode located above a film layer at which the thin film transistor is located; and a planarization layer located between the pixel electrode and the reflection layer.

Abstract: A device for preparation of a composite for on-site pipeline reinforcement includes: a temperature control stirring unit, an infiltration unit, and a vacuum unit, which are communicated in sequence, the infiltration unit includes a spindle, reinforced fiber cloth, a flow-guiding net, and a vacuum bag film sleeved outside the spindle, the reinforced fiber cloth and the flow-guiding net, the spindle is stopped by two baffles, an adhesive feeding joint and an adhesive discharging joint are disposed at two ends of the spindle, respectively, each of the adhesive feeding joint and the adhesive discharging joint includes an inner joint and an outer joint, an outer wall of the inner joint and an outer side of the baffle are covered by a flow-leading net, and the flow-guiding net covered on the outer side of the baffle extends from an edge of the baffle into the adhesive storing compartment of the baffle.

Abstract: An anti-counterfeiting pattern having an optically variable structure, comprising lithographic lines and gravure blind embossed relief lines printed on a carrier. The lithographic lines are a set of lithographic curve lines having a curvature, the widths of the lithographic curve lines changing from thick to thin, or thin to thick. The gravure blind embossed relief lines are a set of curve lines corresponding to the lithographic lines, and having the same curvature. The relief lines are overprinted on the lithographic lines with a width variation identical to that of said lithographic lines. Accurate overprinting of the two printing types forms a curved relief structure wherein the width of the lines changes continuously. When a printed product is rotated and observed, a continuously variable optical effect will be seen, which is visual, readily to identify, anti-copying and difficult to forgery.

Abstract: The present disclosure relates to an eyewear phototherapy device for providing skin cosmetology to the skin surrounding the eyes. The device includes a main spectacle frame having a left supporting member and right supporting member, each including at least one housing assembly extending outward from the each supporting member and facing towards the inner portion of the supporting member. Each of the housing assemblies includes an LED light board, attached to the inner side of the respective housing assembly, which is adapted to emit light energy, a transparent silicone cover attached on the LED light board for protecting direct contact between the LED light board and human skin, a protective element which is adapted to spread the LED emissions around a human eye and provide protection to the human eye from the LED emissions.

Abstract: Cathepsin B plays a crucial role in promoting cancer cells invasion and metastasis. Through structure-guided rational design, Applicants have generated monoclonal antibodies specifically inhibiting human cathepsin B proteolytic activity. These novel antibody inhibitors provide potential potent anti-metastasis therapeutics with excellent safety profiles.

Abstract: A three-dimensional reconstruction method for coronary vessels includes: pretreating a coronary angiography (CAG) image, extracting a vessel edge profile and two-dimensional guide wires, and dividing inner and outer membranes for intravascular ultrasound (IVUS) images; translating the two-dimensional guide wires located in a first angiography plane and a second angiography plane in the CAG image to the same starting point; building perpendicularly intersected curved surfaces; setting an intersecting line as a three-dimensional guide wire; arranging the IVUS images per frame at equal intervals along the three-dimensional guide wire; rotating the IVUS images to positions perpendicular to tangent vectors in corresponding positions; rotating the IVUS images in a vertical plane of the tangent vectors; back projecting the IVUS images to the CAG image; determining optimal orientation angles according to distances from the back projections and the vessel edge profile to the three-dimensional guide wire; and finally r

Abstract: A die-die inspection image can be aligned using a method or system configured to receive a reference image and a test image, determine a global offset and rotation angle from local sections on the reference image and test image, and perform a rough alignment de-skew of the test image prior to performing a fine alignment.

Abstract: The present disclosure describes methods, systems, and articles of manufacture for performing a defect inspection of a die image using adaptive care areas (ACAs). The use of ACAs solve the problem of handling rotations of components that require rotating care areas; handling the situation where each care area requires its own rotation, translation, or affine transformation; and the situation of decoupling intensity differences caused by defects or process variation from intensity differences caused by size variations.

Abstract: Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into the CDR3H. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a stalk domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said stalk domain of the CDR3H. Also described herein are methods and compositions comprising the immunoglobulin constructs described herein for treatment and prevention of a disease or condition in a subject.

Abstract: A cleaning mechanism for clearing a cleaning roller of a cleaner. The cleaning mechanism includes: a cleaning roller for cleaning ground, a clearing component operating to clearing the cleaning roller, and a power unit. The clearing component includes a rotation body and a plurality of clearing elements disposed on the rotation body for clearing a surface of the cleaning roller. The power unit operates to drive the rotation body and the clearing elements to rotate along with the cleaning roller in the same direction. During the rotation of the cleaning roller, the trash is cleared by the clearing elements.

Abstract: Polymers, monomers, chromophoric polymer dots and related methods are provided. Highly fluorescent chromophoric polymer dots with narrow-band emissions are provided. Methods for synthesizing the chromophoric polymers, preparation methods for forming the chromophoric polymer dots, and biological applications using the unique properties of narrow-band emissions are also provided.

Abstract: The present disclosure provides a photoetching mask plate, a method for manufacturing the photoetching mask plate, and a photoetching method using the photoetching mask plate. The photoetching mask plate includes a base substrate, a mask pattern arranged on a surface of the base substrate, and a conductive connection pattern arranged on the surface of the base substrate. The conductive connection pattern is configured to electrically connect separate portions of the mask pattern to each other.

Abstract: A mounting clip that can be used to mount a heat exchanger to a housing, for example, in a HVAC system is disclosed. The mounting clip may include a receiver portion configured to receive, for example, an end portion of the heat exchanger. The mounting clip may also include a clip portion configured to secure the mounting clip to the housing. The mounting clip can be used to mount the heat exchanger to the housing relatively easily, reducing the manufacturing cost and time of the HVAC system.

Abstract: In an approach for generating a file, a computer provides a selection window associated with a second file, wherein the selection window is at least partially transparent and at least partially overlays an opened first file. The computer identifies content within the opened first file that is overlaid by the provided selection window associated with the second file. The computer transfers a copy of the identified content within the opened first file that is overlaid by the provided selection window associated with the second file, wherein the opened first file does not incorporate changes that are made within the second file.

Abstract: A connection device with floatable self-adjusting contacts includes a first main body, a plurality of first and second contact point groups, a second main body, and a plurality of conducting boards (pin boards). The first and second contact groups are respectively disposed on the first and second bodies. The floating board is disposed on the second main body in a floating manner. The conducting board has an insulated main body and a plurality of conducting pins which are disposed on the insulated main body in a floating manner. The conducting pin has a first conducting portion contacting the first contact point, and a second conduct portion contacting the second contact point. The first and second conduct portions respectively have an arc-shaped periphery and an elastic arm. The conducting pins can respectively self-adjust to achieve an optimal downward contacting pressure.