Patents by Inventor Yoshiaki Igarashi

Yoshiaki Igarashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11135234
    Abstract: A compound represented by the following general formula (I) or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutical composition thereof, and the use thereof to prevent or treat infectious diseases and a method to prevent or treat infectious diseases using those regimen are disclosed. The compound represented by formula (I) has an antibacterial activity against both gram-positive and gram-negative bacteria, and is useful in the prevention or treatment of infectious diseases caused by these bacteria.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: October 5, 2021
    Assignees: MICROBIAL CHEMISTRY RESEARCH FOUNDATION, MEIJI SEIKA PHARMA CO., LTD.
    Inventors: Yoshiaki Takahashi, Eijiro Umemura, Takashi Ida, Masayuki Igarashi
  • Patent number: 9512781
    Abstract: In a cooling structure for a recovery-type air-cooled gas turbine combustor having a recovery-type air-cooling structure that bleeds, upstream of the combustor, and pressurizes compressed air supplied from a compressor, that uses the bled and pressurized air to cool a wall, and that recovers and reuses the bled and pressurized air as combustion air for burning fuel in the combustor together with a main flow of the compressed air, wall cooling in which cooling air is supplied to cooling air passages formed in the wall of the combustor to perform cooling involves a downstream wall region, closer to a turbine, that is cooled using the bled and pressurized air as the cooling air and an upstream wall region, closer to a burner, that is cooled using, as the cooling air, bled compressed air bled from a main flow of the compressed air through a housing inner space.
    Type: Grant
    Filed: August 10, 2011
    Date of Patent: December 6, 2016
    Assignees: MITSUBISHI HITACHI POWER SYSTEMS, LTD., TOHOKU ELECTRIC POWER CO., INC.
    Inventors: Satoshi Mizukami, Tatsuo Ishiguro, Junichiro Masada, Kazumasa Takata, Shunsuke Torii, Yuya Fukunaga, Tetsu Konishi, Yoshiaki Nishimura, Yoshiaki Igarashi, Shinya Ishikawa
  • Patent number: 8809362
    Abstract: To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. The marker for determining sensitivity to an anti-cancer agent is formed of one or more substances selected from the group consisting of a substance or a fragment thereof detected as an anion at m/z of 149.05 to 149.06, a substance or a fragment thereof detected as an anion at m/z of 152.99 to 153.00, a substance or a fragment thereof detected as a cation at m/z of 724.34 to 724.35, the peaks being determined by means of a mass spectrometer, glycerol 3-phosphate, dihydrobiopterin, GABA, lactic acid, asparagine, aspartic acid, 2-methylbutyroylcarnitine, 1-methyladenosine, and glutathione, and a substance involved in a metabolic pathway of any of these substances.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: August 19, 2014
    Assignees: Keio University, Kabushiki Kaisha Yakult Honsha
    Inventors: Yusuke Tanigawara, Tetsuya Suzuki, Akito Nishimuta, Shinji Sugimoto, Yoshiaki Igarashi
  • Publication number: 20130098063
    Abstract: In a cooling structure for a recovery-type air-cooled gas turbine combustor having a recovery-type air-cooling structure that bleeds, upstream of the combustor, and pressurizes compressed air supplied from a compressor, that uses the bled and pressurized air to cool a wall, and that recovers and reuses the bled and pressurized air as combustion air for burning fuel in the combustor together with a main flow of the compressed air, wall cooling in which cooling air is supplied to cooling air passages formed in the wall of the combustor to perform cooling involves a downstream wall region, closer to a turbine, that is cooled using the bled and pressurized air as the cooling air and an upstream wall region, closer to a burner, that is cooled using, as the cooling air, bled compressed air bled from a main flow of the compressed air through a housing inner space.
    Type: Application
    Filed: August 10, 2011
    Publication date: April 25, 2013
    Applicants: TOHOKU ELECTRIC POWER CO., LTD., MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventors: Satoshi Mizukami, Tatsuo Ishiguro, Junichiro Masada, Kazumasa Takata, Shunsuke Torii, Yuya Fukunaga, Tetsu Konishi, Yoshiaki Nishimura, Yoshiaki Igarashi, Shinya Ishikawa
  • Publication number: 20120220618
    Abstract: To provide a marker for determining sensitivity of a patient to an anti-cancer agent, and novel cancer therapeutic means employing the marker. The marker for determining sensitivity to an anti-cancer agent is formed of one or more substances selected from the group consisting of a substance or a fragment thereof detected as an anion at m/z of 149.05 to 149.06, a substance or a fragment thereof detected as an anion at m/z of 152.99 to 153.00, a substance or a fragment thereof detected as a cation at m/z of 724.34 to 724.35, the peaks being determined by means of a mass spectrometer, glycerol 3-phosphate, dihydrobiopterin, GABA, lactic acid, asparagine, aspartic acid, 2-methylbutyroylcarnitine, 1-methyladenosine, and glutathione, and a substance involved in a metabolic pathway of any of these substances.
    Type: Application
    Filed: October 29, 2010
    Publication date: August 30, 2012
    Applicants: Kabushiki Kaisha Yakult Honsha, Keio University
    Inventors: Yusuke Tanigawara, Tetsuya Suzuki, Akito Nishimuta, Shinji Sugimoto, Yoshiaki Igarashi
  • Patent number: 7887751
    Abstract: A reagent cassette used in an automatic analyzer for a clinical examination room, which provides an analysis environment enabling an operator to select reagent bottles with proper capacities depending on the number of tests to be performed in each different type of facility and to properly set reagents with ease. In the automatic analyzer comprising a sample pipetting section, a reagent pipetting section, a reaction cuvette, etc., one component in a sample is analyzed by using the reagent cassette in which one or a plurality of reagent bottles containing two or more types of reagents are combined together. The reagent cassette is provided with a reagent identifier including information regarding the presence or absence of a reagent opening of the reagent bottle for each of a plurality of positions of the openings.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: February 15, 2011
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Tomonori Mimura, Masaaki Hanawa, Masaharu Nishida, Yoshiaki Igarashi, Yoshimitsu Takagi
  • Publication number: 20100249089
    Abstract: The present invention relates to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. The invention provides an acrylonitrile derivative represented by formula (1): (wherein A represents an optionally substituted 3- to 8-membered heterocyclic ring) or a salt thereof.
    Type: Application
    Filed: December 2, 2008
    Publication date: September 30, 2010
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Ryuta Yamazaki, Hiroshi Hatano, Takashi Yaegashi, Yoshiaki Igarashi, Oh Yoshida, Yoshikazu Sugimoto
  • Patent number: 7579736
    Abstract: A three-phase DC brushless motor and coil winding method provide a coil winding enabling consistent starting with PWM sensorless driving by suppressing the DC offset component of the induced voltage resulting from an imbalance in the motor coil windings. The method of winding the armature winding of the three-phase DC brushless motor renders the difference in mutual inductance substantially zero.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: August 25, 2009
    Assignee: Panasonic Corporation
    Inventors: Hideki Nishino, Kiyotaka Tanimoto, Taishii Iwanaga, Shinichi Kuroshima, Yoshiaki Igarashi
  • Patent number: 7365506
    Abstract: A motor driving part has half bridge circuits in which a high potential side drive transistor and a low potential side drive transistor are connected in series to each other, and a connection point therebetween serves as a stator winding driving terminal of each phase of a motor. A rotor position detector detects a rotor position of the motor and outputs a rotor position signal. The current phase detector detects the phase of a phase current flowing in the stator winding driving terminal. A voltage signal generator controls and generates a voltage profile signal such that a first phase difference that is a difference between the phase of the phase current and the phase of the rotor position signal is kept to a predetermined electrical angle. A driving signal generator generates a PWM signal that drives the drive transistor of each phase depending on the voltage profile signal.
    Type: Grant
    Filed: June 13, 2005
    Date of Patent: April 29, 2008
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Yasunori Yamamoto, Hideaki Mori, Yoshiaki Igarashi
  • Patent number: 7298106
    Abstract: A rotor position sensorless multiphase motor driving device includes a rotor; a plurality of phase windings; a common terminal to which one terminal of terminals at both ends of each winding is star connected; an upper-side drive transistor and a lower-side drive transistor connected to the other terminal of the winding; a commutation control unit operable to select two terminals other than the common terminal of the windings, and to turn on the corresponding pair of upper-side drive transistor and the lower-side drive transistor; a rotor position search pulse applying unit operable to apply a search pulse to the selected two terminals; and a comparing unit operable to detect a rotor position based on a response signal generated between the terminal which was unselected and the common terminal according to the search pulse application.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: November 20, 2007
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Yasunori Yamamoto, Hideaki Mori, Shinichi Kuroshima, Yoshiaki Igarashi
  • Publication number: 20070018599
    Abstract: A rotor position sensorless multiphase motor driving device includes a rotor; a plurality of phase windings; a common terminal to which one terminal of terminals at both ends of each winding is star connected; an upper-side drive transistor and a lower-side drive transistor connected to the other terminal of the winding; a commutation control unit operable to select two terminals other than the common terminal of the windings, and to turn on the corresponding pair of upper-side drive transistor and the lower-side drive transistor; a rotor position search pulse applying unit operable to apply a search pulse to the selected two terminals; and a comparing unit operable to detect a rotor position based on a response signal generated between the terminal which was unselected and the common terminal according to the search pulse application.
    Type: Application
    Filed: July 21, 2006
    Publication date: January 25, 2007
    Inventors: Yasunori Yamamoto, Hideaki Mori, Shinichi Kuroshima, Yoshiaki Igarashi
  • Patent number: 7122980
    Abstract: A motor driving apparatus includes a comparator, a threshold controller, a position determining unit, a phase-switching controller, and a current output unit. While the rotor is stopped, the phase-switching controller supplies a predetermined phase of winding with a current pulse having a predetermined pulse width so as not to cause the rotor to react and operate, in order to determine the initial position of the rotor. The position determining unit determines an initial position of the rotor based on the result of comparison between the induced voltage generated in a non-conduction phase by the current pulse and the threshold. The phase-switching controller performs energization or commutation according to the determined initial position of the rotor to start up the motor.
    Type: Grant
    Filed: October 3, 2005
    Date of Patent: October 17, 2006
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Shinichi Kuroshima, Yoshiaki Igarashi, Hideaki Mori
  • Publication number: 20060214529
    Abstract: A three-phase DC brushless motor and coil winding method provide a coil winding enabling consistent starting with PWM sensorless driving by suppressing the DC offset component of the induced voltage resulting from an imbalance in the motor coil windings. The method of winding the armature winding of the three-phase DC brushless motor renders the difference in mutual inductance substantially zero.
    Type: Application
    Filed: March 21, 2006
    Publication date: September 28, 2006
    Inventors: Hideki Nishino, Kiyotaka Tanimoto, Taishi Iwanaga, Shinichi Kuroshima, Yoshiaki Igarashi
  • Publication number: 20060076911
    Abstract: A motor driving apparatus includes a comparator, a threshold controller, a position determining unit, a phase-switching controller, and a current output unit. While the rotor is stopped, the phase-switching controller supplies a predetermined phase of winding with a current pulse having a predetermined pulse width so as not to cause the rotor to react and operate, in order to determine the initial position of the rotor. The position determining unit determines an initial position of the rotor based on the result of comparison between the induced voltage generated in a non-conduction phase by the current pulse and the threshold. The phase-switching controller performs energization or commutation according to the determined initial position of the rotor to start up the motor.
    Type: Application
    Filed: October 3, 2005
    Publication date: April 13, 2006
    Inventors: Shinichi Kuroshima, Yoshiaki Igarashi, Hideaki Mori
  • Publication number: 20050275362
    Abstract: A motor driving device that is low in cost and capable to control the phase of a motor with high efficiency and with accuracy. A motor driving device includes a motor driving part, a rotor position detector, a current phase detector, a voltage signal generator, and a driving signal generator. The motor driving part has a plurality of half bridge circuits in which a high potential side drive transistor and a low potential side drive transistor are connected in series to each other, and a connection point therebetween serves as a stator winding driving terminal of each phase of a motor. The rotor position detector detects a rotor position of the motor and outputting a rotor position signal. The current phase detector detects the phase of a phase current flowing in the stator winding driving terminal.
    Type: Application
    Filed: June 13, 2005
    Publication date: December 15, 2005
    Inventors: Yasunori Yamamoto, Hideaki Mori, Yoshiaki Igarashi
  • Publication number: 20050142040
    Abstract: A reagent container used for automatic analysis in an automatic analyzer, which enables reagents to be set with ease and which can increase flexibility in selecting combinations of the reagents. In an automatic analyzer for analyzing components of a biological sample by using two or more kinds of reagents, reagent containers containing the two or more kinds of reagents are jointed into one reagent cassette with the aid of a recess and a projection provided in and on the reagent containers, a reagent holder, bonding, tape binding, etc. Thus, a plurality of reagents used for one analysis item are combined with each other in one cassette corresponding to one analysis item. A reagent container for use in automatic analysis, which is easy to handle and highly flexible in setting of reagents, can be provided.
    Type: Application
    Filed: December 3, 2004
    Publication date: June 30, 2005
    Inventors: Masaaki Hanawa, Isao Yamazaki, Hitoshi Tokieda, Tomonori Mimura, Tadashi Oishi, Yoshiaki Igarashi, Masaharu Nishida, Takeshi Sato
  • Publication number: 20050084886
    Abstract: The present invention absorbs and captures nucleic components from various specimens by a single stationary phase and finally recovers the nucleic components by eluting the captured nucleic components from the stationary phase. This invention enables recovery of nucleic components without reducing the concentrations of nucleic acids and detection of specific nucleic components such as specific viruses.
    Type: Application
    Filed: October 5, 2004
    Publication date: April 21, 2005
    Inventors: Yoshiaki Igarashi, Toshinari Sakurai, Toshiaki Yokobayashi
  • Publication number: 20050084426
    Abstract: A reagent cassette used in an automatic analyzer for a clinical examination room, which provides an analysis environment enabling an operator to select reagent bottles with proper capacities depending on the number of tests to be performed in each different type of facility and to properly set reagents with ease. In the automatic analyzer comprising a sample pipetting section, a reagent pipetting section, a reaction cuvette, etc., one component in a sample is analyzed by using the reagent cassette in which one or a plurality of reagent bottles containing two or more types of reagents are combined together. The reagent cassette is provided with a reagent identifier including information regarding the presence or absence of a reagent opening of the reagent bottle for each of a plurality of positions of the openings.
    Type: Application
    Filed: October 14, 2004
    Publication date: April 21, 2005
    Inventors: Tomonori Mimura, Masaaki Hanawa, Masaharu Nishida, Yoshiaki Igarashi, Yoshimitsu Takagi
  • Patent number: 6815215
    Abstract: The present invention absorbs and captures nucleic components from various specimens by a single stationary phase and finally recovers the nucleic components by eluting the captured nucleic components from the stationary phase. This invention enables recovery of nucleic components without reducing the concentrations of nucleic acids and detection of specific nucleic components such as specific viruses.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: November 9, 2004
    Assignee: Hitachi, Ltd.
    Inventors: Yoshiaki Igarashi, Toshinari Sakurai, Toshiaki Yokobayashi
  • Patent number: 6676968
    Abstract: A medicinal composition containing one or more compounds selected from the compounds represented by the following formula (I), salts of these compounds, solvates of these compounds and solvates of these salts and being capable of reducing the contact of the compounds with the components in the bile or pancreatic juice.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: January 13, 2004
    Assignee: Teijin Limited
    Inventors: Kiyoyuki Sakon, Masahiko Narasaki, Kentaro Fujinaga, Yoji Yamamoto, Hiroaki Mitsuhashi, Kazuoki Tsuruta, Hirofumi Tanabe, Yoshiaki Igarashi