Abstract: An adsorbent, which can be produced by a method in which a particle size, a pore size, a specific surface area or the like can be easily controlled, and is suitable for isolation of biomolecules. The adsorbent contains aggregates of calcium phosphate-based particles, and has an average pore size of 15 to 36 nanometers and a specific surface area of 40 to 90 m2/mL when measurement is carried out by mercury porosimetry.

Abstract: A machine tool includes a spindle equipped with a workpiece gripping portion arranged so as to face an operator side, the spindle being configured to rotatably drive a workpiece gripped by the workpiece gripping portion, and a tool mount equipped with a rotary member supporting a plurality of tools in a rotatably indexable manner about an axis parallel to an axis of the spindle. The tool mount is arranged at a tool mount installation portion formed to be positioned on the operator side in a manner such that the rotary member faces a workpiece gripping portion side.

Abstract: The present invention provides a porous cellulose gel having a high mechanical strength capable of being operated at a higher flow rate, and a method for producing the same. To a suspension liquid of cellulose particles, a crosslinking agent in an amount of from 4 to 12 times the amount of the cellulose monomer in terms of moles and an alkali in an amount of from 0.1 to 1.5 times the amount of the crosslinking agent in terms of moles are added continuously dropwise or added dividedly over a prescribed period of time, whereby flow rate characteristics of a resulting porous cellulose gel can be enhanced. According to the invention, the production efficiency of a polymer substance, such as a nucleic acid and a protein can be enhanced.

Abstract: A chip discharging device of a machine tool is equipped with a chip discharging member for discharging chips generated by machine processing to a workpiece to an outside of the machine tool, and a chip shooter for introducing the chips to the chip discharging member. The chip shooter connects an introducing opening for introducing the generated chips and a discharging opening for discharging the chips toward the chip discharging member by a guide wall surface. The guide wall surface includes a vertical wall surface and a plurality of inclined wall surfaces inclined with respect to the vertical wall surface. At least a boundary parts between the inclined wall surfaces and a boundary part between the inclined wall surface and the vertical wall surface are formed by a flat surface or a curved surface.

Abstract: A method for preparing a chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using the chromatography medium are provided. The chromatography medium is obtained by forming a sulfated polysaccharide bound with porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: A Chromatography medium having the properties of high virus adsorption and high fluidity, and a method for producing a virus vaccine using these are provided. The Chromatography medium is formed by binding a sulfated polysaccharide to porous particles having an exclusion limit molecular weight of 6000 Da or less when pure water is used as mobile phase and standard polyethylene glycol is used and an average particle size in the range of 30-200 ?m.

Abstract: A chromatography media having excellent salt tolerance, adsorption characteristics and so forth is provided. The chromatography media contains a base media involving porous particles and polyamine bonded with the base media, in which 20 to 40% of amino groups in the polyamine is modified with a hydrophobic group.

Abstract: In a lathe equipped with a spindle for rotatably driving a work and a tool rest having a turret (rotary member) rotatably supporting a plurality of tools in an indexable manner about a horizontal axis, the tool rest is detachably installed on a tool rest installation portion formed so as to be positioned on an operator side so that the tools of the turret face the work side gripped by the spindle in an attachable and detachable manner.

Abstract: A machine tool includes a spindle equipped with a workpiece gripping portion arranged so as to face an operator side, the spindle being configured to rotatably drive a workpiece gripped by the workpiece gripping portion, and a tool mount equipped with a rotary member supporting a plurality of tools in a rotatably indexable manner about an axis parallel to an axis of the spindle. The tool mount is arranged at a tool mount installation portion formed to be positioned on the operator side in a manner such that the rotary member faces a workpiece gripping portion side.

Abstract: A chip discharging device of a machine tool is equipped with a chip discharging member for discharging chips generated by machine processing to a workpiece to an outside of the machine tool, and a chip shooter for introducing the chips to the chip discharging member. The chip shooter connects an introducing opening for introducing the generated chips and a discharging opening for discharging the chips toward the chip discharging member by a guide wall surface. The guide wall surface includes a vertical wall surface and a plurality of inclined wall surfaces inclined with respect to the vertical wall surface. At least a boundary parts between the inclined wall surfaces and a boundary part between the inclined wall surface and the vertical wall surface are formed by a flat surface or a curved surface.

Abstract: A cation exchange chromatography media for purifying of the antibody comprises a base media involving porous particles and a polymer containing, in the range of 30 to 100 mol % based on the total monomer, at least one kind of strong cation exchange monomer unit represented by formula (1) or formula (2), and ion exchange capacity of the cation exchange chromatography media is from 60 to 300 ?mol/mL: (wherein, R1, R2 and R3 are each independently a hydrogen atom or methyl, A1 and A2 are —R4—SO3M, here, R4 is alkylene having 2 to 4 carbons, and M is a hydrogen atom, Na or K.).

Abstract: A polyisocyanate composition is produced by reaction of bis(isocyanatomethyl)cyclohexane with trimethylolpropane, and contains a trimethylolpropane-monomolecular-body obtained by reaction of three molecules of bis(isocyanatomethyl)cyclohexane with one molecule of trimethylolpropane, and a trimethylolpropane-bimolecular-body obtained by reaction of five molecules of bis(isocyanatomethyl)cyclohexane with two molecules of trimethylolpropane; and the molar ratio of trimethylolpropane-monomolecular-body relative to trimethylolpropane-bimolecular-body (trimethylolpropane-monomolecular-body/trimethylolpropane-bimolecular-body) contained in the polyisocyanate composition is 1.5 or more and 4.5 or less.

Abstract: The present invention provides a chromatography packing material having improved flow rate characteristics and adsorption characteristics. In particular, the present invention provides a chromatography packing material suitable for separation and purification of immunoglobulin in the manufacture of antibody preparations. A porous cellulose gel, which is made by adding polysaccharides having a limiting viscosity of 0.21 to 0.90 dL/g to porous cellulose particles, the dry weight per unit volume of the porous cellulose gel being 1.06 to 1.40 times the dry weight per unit volume of the porous cellulose particles, is used. By adding a predetermined amount of polysaccharides having a predetermined limiting viscosity to porous cellulose particles, flow rate characteristics and adsorption characteristics can be improved.

Abstract: The present invention provides a porous cellulose gel having a high mechanical strength capable of being operated at a higher flow rate, and a method for producing the same. To a suspension liquid of cellulose particles, a crosslinking agent in an amount of from 4 to 12 times the amount of the cellulose monomer in terms of moles and an alkali in an amount of from 0.1 to 1.5 times the amount of the crosslinking agent in terms of moles are added continuously dropwise or added dividedly over a prescribed period of time, whereby flow rate characteristics of a resulting porous cellulose gel can be enhanced. According to the invention, the production efficiency of a polymer substance, such as a nucleic acid and a protein can be enhanced.

Abstract: The present invention provides a porous cellulose gel having a high mechanical strength capable of being operated at a higher flow rate, and a method for producing the same. To a suspension liquid of cellulose particles, a crosslinking agent in an amount of from 4 to 12 times the amount of the cellulose monomer in terms of moles and an alkali in an amount of from 0.1 to 1.5 times the amount of the crosslinking agent in terms of moles are added continuously dropwise or added dividedly over a prescribed period of time, whereby flow rate characteristics of a resulting porous cellulose gel can be enhanced. According to the invention, the production efficiency of a polymer substance, such as a nucleic acid and a protein can be enhanced.

Abstract: Disclosed is a composition comprising a therapeutically effective amount of (a) at least one compound from the group of 5-fluorouracil, 5-fluorodeoxyuridine, capecitabine or a prodrug of such compounds; and (b) 5-hydroxymethyl-2?-deoxyuridine, or a prodrug of such compound, as well as kits comprising such composition and methods of use thereof for treating neoplasia.

Abstract: The control apparatus according to the invention includes a keypad detachable from the control apparatus and including a communication device that facilitates communicating with a personal computer such that the keypad detached from the control apparatus is connected to the personal computer for setting the operations of the control apparatus and, then, the keypad is attached to the control apparatus to make the control apparatus conduct the control operations based on the setting contents set in the keypad. The control apparatus according to the invention facilitates setting the operations thereof in any place different from the place, therein the control apparatus is installed, and reducing the electric power fed to the control apparatus during the setting operation.

Abstract: In a structure for mounting an electric vacuum pump 1 to a vehicle body frame 3 via a bracket 2, the bracket 2 includes a wobble suppression portion 2F that is formed so as to surround a portion of the electric vacuum pump 1 at a position vertically apart from a pump mounting portion 2B, and a wobble prevention mount 5 that suppresses wobbling of the electric vacuum pump 1 in abutment against the electric vacuum pump 1 is mounted to the wobble suppression portion 2F.

Abstract: An inverter device is provided that can measure a decrease in cooling capacity caused by a finite service life of a cooling fan or clogging of a cooling fin, without being affected by an ambient temperature or a load state. A thermal time constant is calculated in a thermal time constant calculation circuit from a temperature detection value from a temperature detection circuit and a time signal from a timer on the basis of an operation/stop command for the inverter device. The calculated value of the thermal time constant calculated in the thermal time constant calculation circuit is compared by a comparator with a reference value of the thermal time constant that is stored in advance in a memory. Whether the cooling capacity has decreased is determined based on the comparison results.

Abstract: The present invention provides a chromatography packing material having improved flow rate characteristics and adsorption characteristics. In particular, the present invention provides a chromatography packing material suitable for separation and purification of immunoglobulin in the manufacture of antibody preparations. A porous cellulose gel, which is made by adding polysaccharides having a limiting viscosity of 0.21 to 0.90 dL/g to porous cellulose particles, the dry weight per unit volume of the porous cellulose gel being 1.06 to 1.40 times the dry weight per unit volume of the porous cellulose particles, is used. By adding a predetermined amount of polysaccharides having a predetermined limiting viscosity to porous cellulose particles, flow rate characteristics and adsorption characteristics can be improved.