Patents by Inventor Yoshiyuki Fukase

Yoshiyuki Fukase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMIDE COMPOUND
    Publication number: 20170107240
    Abstract: The present invention relates to compound (I) or a salt thereof which has a ROR?t inhibitory action. In the formula (I), each symbol is as defined in the specification.
    Type: Application
    Filed: July 2, 2014
    Publication date: April 20, 2017
    Inventors: Satoshi Yamamoto, Junya Shirai, Mitsunori Kono, Yoshihide Tomata, Ayumu Sato, Atsuko Ochida, Yoshiyuki Fukase, Shoji Fukumoto, Tsuneo Oda, Hidekazu Tokuhara, Naoki Ishii, Yusuke Sasaki
  • HETEROCYCLIC COMPOUND
    Publication number: 20170050974
    Abstract: The present invention relates to compound (I) or a salt thereof which has a ROR?t inhibitory action. wherein each symbol is as defined in the specification.
    Type: Application
    Filed: July 2, 2014
    Publication date: February 23, 2017
    Inventors: Satoshi Yamamoto, Junya Shirai, Hiroyuki Watanabe, Shoji Fukumoto, Tsuneo Oda, Hidekazu Tokuhara, Yoshihide Tomata, Naoki Ishii, Michiko Tawada, Mitsunori Kono, Atsuko Ochida, Takashi Imada, Yoshiyuki Fukase, Tomoya Yukawa
  • Heterocyclic compound
    Patent number: 9573903
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: February 21, 2017
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Yamamoto, Junya Shirai, Tsuneo Oda, Mitsunori Kono, Atsuko Ochida, Takashi Imada, Hidekazu Tokuhara, Yoshihide Tomata, Naoki Ishii, Michiko Tawada, Yoshiyuki Fukase, Tomoya Yukawa, Shoji Fukumoto
  • HETEROCYCLIC COMPOUND
    Publication number: 20160229814
    Abstract: The present invention provides a heterocyclic compound having an ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein Ar is a the partial structure (1) to the partial structure (5), Q is a bivalent group selected from the group consisting of (Ia)-(If), and B is a ring optionally having substituent(s), or a salt thereof.
    Type: Application
    Filed: March 13, 2014
    Publication date: August 11, 2016
    Inventors: Satoshi Yamamoto, Junya Shirai, Yoshiyuki Fukase, Ayumu Sato, Mitsunori Kouno, Yoshihide Tomata, Atsuko Ochida, Kazuko Yonemori, Tsuneo Oda, Takashi Imada, Tomoya Yukawa
  • HETEROCYCLIC COMPOUND
    Publication number: 20160176872
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Satoshi YAMAMOTO, Junya SHIRAI, Tsuneo ODA, Mitsunori KONO, Atsuko OCHIDA, Takashi IMADA, Hidekazu TOKUHARA, Yoshihide TOMATA, Naoki ISHII, Michiko TAWADA, Yoshiyuki FUKASE, Tomoya YUKAWA, Shoji FUKUMOTO
  • HETEROCYCLIC COMPOUND
    Publication number: 20160176873
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Satoshi YAMAMOTO, Junya SHIRAI, Tsuneo ODA, Mitsunori KONO, Atsuko OCHIDA, Takashi IMADA, Hidekazu TOKUHARA, Yoshihide TOMATA, Naoki ISHII, Michiko TAWADA, Yoshiyuki FUKASE, Tomoya YUKAWA, Shoji FUKUMOTO
  • HETEROCYCLIC COMPOUND
    Publication number: 20160176822
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Application
    Filed: February 26, 2016
    Publication date: June 23, 2016
    Inventors: Satoshi YAMAMOTO, Junya SHIRAI, Tsuneo ODA, Mitsunori KONO, Atsuko OCHIDA, Takashi IMADA, Hidekazu TOKUHARA, Yoshihide TOMATA, Naoki ISHII, Michiko TAWADA, Yoshiyuki FUKASE, Tomoya YUKAWA, Shoji FUKUMOTO
  • Heterocyclic compound
    Patent number: 9365520
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: June 14, 2016
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Yamamoto, Junya Shirai, Tsuneo Oda, Mitsunori Kono, Atsuko Ochida, Takashi Imada, Hidekazu Tokuhara, Yoshihide Tomata, Naoki Ishii, Michiko Tawada, Yoshiyuki Fukase, Tomoya Yukawa, Shoji Fukumoto
  • HETEROCYCLIC COMPOUND AND USE THEREOF
    Publication number: 20160046601
    Abstract: Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Application
    Filed: October 28, 2015
    Publication date: February 18, 2016
    Inventors: Takanobu KUROITA, Yasuhiro IMAEDA, Kouichi IWANAGA, Naohiro TAYA, Hidekazu TOKUHARA, Yoshiyuki FUKASE
  • HETEROCYCLIC COMPOUND
    Publication number: 20160002169
    Abstract: The present invention provides a heterocyclic compound having a ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
    Type: Application
    Filed: June 30, 2015
    Publication date: January 7, 2016
    Inventors: Satoshi YAMAMOTO, Junya SHIRAI, Tsuneo ODA, Mitsunori KONO, Atsuko OCHIDA, Takashi IMADA, Hidekazu TOKUHARA, Yoshihide TOMATA, Naoki ISHII, Michiko TAWADA, Yoshiyuki FUKASE, Tomoya YUKAWA, Shoji FUKUMOTO
  • Heterocyclic compound
    Patent number: 9156837
    Abstract: A heterocyclic compound having an ROR?t inhibitory activity, which is a compound of formula (I) or a salt thereof is provided. The compound has ring A, which is an optionally substituted cyclic group and is bound to a pyrazole ring though Q. Q is a bond, optionally substituted C1-10 alkylene, optionally substituted C2-10 alkenylene, or optionally substituted C2-10 alkynylene. R1 is a substituent. Ring B is a thiazole ring, an isothiazole ring or a dihydrothiazole ring, each of which is optionally further substituted by a substituent in addition to R2.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: October 13, 2015
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Yamamoto, Junya Shirai, Atsuko Ochida, Yoshiyuki Fukase, Yoshihide Tomata, Ayumu Sato, Shotaro Miura, Kazuko Yonemori, Ryokichi Koyama
  • Condensed heterocyclic compound
    Patent number: 9120776
    Abstract: The present invention provides a fused heterocyclic compound having an ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I?): wherein each symbol is as defined in the specification, provided that 2-(2-((4-cyanophenyl)amino)-2-oxoethoxy)-N-(9-ethyl-9H-carbazol-3-yl)acetamide and N-(4-cyanophenyl)-N?-(9-ethyl-9H-carbazol-3-yl)-3-methylpentanediamide are excluded, or a thereof.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: September 1, 2015
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Yamamoto, Junya Shirai, Yoshiyuki Fukase, Yoshihide Tomata, Ayumu Sato, Atsuko Ochida, Kazuko Yonemori, Hideyuki Nakagawa
  • HETEROCYCLIC COMPOUND AND USE THEREOF
    Publication number: 20150191486
    Abstract: Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Application
    Filed: March 23, 2015
    Publication date: July 9, 2015
    Inventors: Takanobu KUROITA, Yasuhiro IMAEDA, Kouichi IWANAGA, Naohiro TAYA, Hidekazu TOKUHARA, YOSHIYUKI FUKASE
  • CONDENSED HETEROCYCLIC COMPOUND
    Publication number: 20140228409
    Abstract: The present invention provides a fused heterocyclic compound having an ROR?t inhibitory action. The present invention relates to a compound represented by the formula (I?): wherein each symbol is as defined in the specification, provided that 2-(2-((4-cyanophenyl)amino)-2-oxoethoxy)-N-(9-ethyl-9H-carbazol-3-yl)acetamide and N-(4-cyanophenyl)-N?-(9-ethyl-9H-carbazol-3-yl)-3-methylpentanediamide are excluded, or a salt thereof.
    Type: Application
    Filed: September 21, 2012
    Publication date: August 14, 2014
    Inventors: Satoshi Yamamoto, Junya Shirai, Yoshiyuki Fukase, Yoshihide Tomata, Ayumu Sato, Atsuko Ochida, Kazuko Yonemori, Hideyuki Nakagawa
  • HETEROCYCLIC COMPOUND
    Publication number: 20140163001
    Abstract: Provided is a heterocyclic compound having an ROR?t inhibitory activity.
    Type: Application
    Filed: July 27, 2012
    Publication date: June 12, 2014
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Satoshi Yamamoto, Junya Shirai, Atsuko Ochida, Yoshiyuki Fukase, Yoshihide Tomata, Ayumu Sato, Shotaro Miura, Kazuko Yonemori, Ryokichi Koyama
  • Heterocyclic compound and use thereof
    Patent number: 8466282
    Abstract: Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: June 18, 2013
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Takanobu Kuroita, Yasuhiro Imaeda, Kouichi Iwanaga, Naohiro Taya, Hidekazu Tokuhara, Yoshiyuki Fukase
  • Amide compounds and use of the same
    Patent number: 8329691
    Abstract: A renin inhibitor comprising a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof. The compound of the present invention has a superior renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: December 11, 2012
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yasuhiro Imaeda, Takanobu Kuroita, Yoshiyuki Fukase, Shinkichi Suzuki, Michiko Tawada
  • HETEROCYCLIC COMPOUND AND USE THEREOF
    Publication number: 20120264733
    Abstract: Compounds represented by the formulas wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 18, 2012
    Inventors: Takanobu KUROITA, Yasuhiro Imaeda, Kouichi Iwanaga, Naohiro Taya, Hidekazu Tokuhara, Yoshiyuki Fukase
  • HETEROCYCLIC COMPOUND AND USE THEREOF
    Publication number: 20110178057
    Abstract: Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a pro-drug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Application
    Filed: June 17, 2009
    Publication date: July 21, 2011
    Inventors: Takanobu Kuroita, Yasuhiro Imaeda, Kouichi Iwanaga, Naohiro Taya, Hidekazu Tokuhara, Yoshiyuki Fukase
  • AMIDE COMPOUNDS AND USE OF THE SAME
    Publication number: 20100324010
    Abstract: A renin inhibitor comprising a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof. The compound of the present invention has a superior renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
    Type: Application
    Filed: October 14, 2008
    Publication date: December 23, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Yasuhiro Imaeda, Takanobu Kuroita, Yoshiyuki Fukase, Shinkichi Suzuki, Michiko Amano