Patents by Inventor Yoshiyuki Fukase

Yoshiyuki Fukase has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazole derivative and use thereof
    Patent number: 7803822
    Abstract: The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula —NHCOR4, —NHSO2R5, —NHCON(R6a)(R6b), —NHCOOR7 or —CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: September 28, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kubo, Mamoru Tobisu, Eiji Honda, Takahiko Taniguchi, Yoshiyuki Fukase, Masaki Kawamura, Masaharu Nakayama
  • Substituted imidazole compound and use thereof
    Publication number: 20090227560
    Abstract: The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof. The compound of the present invention has a superior renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension, and the like.
    Type: Application
    Filed: July 11, 2008
    Publication date: September 10, 2009
    Inventors: Takanobu Kuroita, Tsuneo Oda, Yasutomi Asano, Naohiro Taya, Kouichi Iwanaga, Hidekazu Tokuhara, Yoshiyuki Fukase
  • Substituted imidazole compound and use thereof
    Publication number: 20090156612
    Abstract: The present invention relates to a compound represented by the formula: wherein each symbol is as defined in the description, or a salt thereof or a prodrug thereof. The compound of the present invention has a superior renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension, and the like.
    Type: Application
    Filed: April 23, 2008
    Publication date: June 18, 2009
    Inventors: Takanobu Kuroita, Tsuneo Oda, Yasutomi Asano, Naohiro Taya, Kouichi Iwanaga, Hidekazu Tokuhara, Yoshiyuki Fukase
  • Triazole Derivative and Use Thereof
    Publication number: 20090105253
    Abstract: The present invention relates to a thrombin receptor antagonist containing a compound represented by the formula (I) wherein R1a, R1b and R2 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, or an optionally substituted alkoxy, R3 is a group represented by the formula —NHCOR4, —NHSO2R5, —NHCON(R6a)(R6b), —NHCOOR7 or —CONHR8 wherein R4, R5, R6a, R6b, R7 and R8 are each a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group and the like), ring A is monocyclic aromatic ring optionally further having substituent(s), R1a and R1b are optionally bonded to each other to form an optionally substituted nitrogen-containing non-aromatic heterocycle, or a salt thereof or a prodrug thereof.
    Type: Application
    Filed: April 6, 2006
    Publication date: April 23, 2009
    Inventors: Keiji Kubo, Mamoru Tobisu, Eiji Honda, Takahiko Taniguchi, Yoshiyuki Fukase, Masaki Kawamura, Masaharu Nakayama