Publication number: 20140011881
Abstract: This present disclosure relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present disclosure provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.
Type:
Application
Filed:
September 10, 2013
Publication date:
January 9, 2014
Applicant:
Amorepacific Corporation
Inventors:
Song Seok SHIN, Jin Kwan KIM, Sun-Young KIM, Ki-Wha LEE, Byoung young WOO, Joo-Hyun MOH, Yeon Su JEONG, Kyung Min LIM, Jin Kyu CHOI, Hyun-Ju KOH, Young-Ho PARK