Abstract: The present application provides a medicament having an anti-inflammatory bowel disease function, and a preparation method therefor and an application thereof. The medicament has a structure as represented in formula I or formula II. The medicament and a pharmaceutically acceptable salt, a solvate, a prodrug, a tautomer, a stereoisomer, or a pharmaceutical composition thereof provided by the present application have a good effect on inflammatory bowel diseases, can be used for preparing medicaments for treating the inflammatory bowel diseases, and have important clinical significance and wide application prospects.

Abstract: Embodiments of the invention are intended to evaluate the performance of a planning module of the ADV in terms of decision consistency in addition to other metrics, such as comfort, latency, controllability, and safety. In one embodiment, an exemplary method includes receiving, at an autonomous driving simulation platform, a record file recorded by the ADV that was automatically driving on a road segment; simulating operations of a dynamic model of the ADV in the autonomous driving simulation platform during one or more driving scenarios on the road segment based on the record file. The method further includes performing a comparison between each planned trajectory generated by a planning module of the dynamic model after an initial period of time with each trajectory stored in a buffer; and modifying a performance score generated by a planning performance profiler in the autonomous driving simulation platform based on a result of the comparison.

Abstract: Systems, methods, and media for factoring localization uncertainty of an ADV into its planning and control process to increase the safety of the ADV. The uncertainty of the localization can be caused by sensor inaccuracy, map matching algorithm inaccuracy, and/or speed uncertainty. The localization uncertainty can have negative impact on trajectory planning and vehicle control. Embodiments described herein are intended to increase the safety of the ADV by considering localization uncertainty in trajectory planning and vehicle control. An exemplary method includes determining a confidence region for an ADV that is automatically driving on a road segment based on localization uncertainty and speed uncertainty; determining that an object is within the confidence region, and a probability of collision with the ADV based on a distance of the object to the ADV; and planning a trajectory based on the probability of collision, and controlling the ADV based on the probability of collision.

Abstract: In one embodiment, an exemplary method includes receiving, at a simulation platform, a record file recorded by a manually-driving ADV on a road segment, the simulation platform including a first encoder, a second encoder, and a performance evaluator; simulating automatic driving operations of a dynamic model of the ADV on the road segment based on the record file, the dynamic model including an autonomous driving module to be evaluated. The method further includes: for each trajectory generated by the autonomous driving module during the simulation: extracting a corresponding trajectory associated with the manually-driving ADV from the record file, encoding the trajectory into a first semantic map and the corresponding trajectory into a second semantic map, and generating a similarity score based on the first semantic map and the second semantic map. The method also includes generating an overall performance score based on each similarity score.

Abstract: One or more outputs from a planning module of an ADV are received. Data of a driving environment of the ADV is received. A performance of the planning module is evaluated by determining a score of the performance of the planning module based on the data of the driving environment and the one or more outputs from the planning module. Whether the one or more outputs from the planning module violates at least one of a set of safety rules is determined. The score is determined being larger than a predetermined threshold in response to determining that the one or more outputs from the planning module violate at least one of the set of safety rules. Otherwise, the score is determined based on a machine learning model. The planning module is modified by tuning a set of parameters of the planning module based on the score.

Abstract: According to various embodiments, systems, methods, and media for evaluating an open space planner in an autonomous vehicle are disclosed. In one embodiment, an exemplary method includes receiving, at a profiling application, a record file recorded by the ADV while driving in an open space using the open space planner, and a configuration file specifying parameters of the ADV; extracting planning messages and prediction messages from the record file, each extracted message being associated with the open space planner. The method further includes generating features from the planning message and the prediction messages in view of the specified parameters of the ADV; and calculating statistical metrics from the features. The statistical metrics are then provided to an automatic tuning framework for tuning the open space planner.

Abstract: An improved methods and systems for detecting defect(s) on a mask are disclosed. An improved method comprises inspecting an exposed wafer after the wafer was exposed, by a lithography system using a mask, with a selected process condition that is determined based on a mask defect printability under the selected process condition; and identifying, based on the inspection, a wafer defect that is caused by a defect on the mask to enable identification of the defect on the mask.

Abstract: In one embodiment, an exemplary method includes the operations of receiving, at a profiling application, a record file recorded by the ADV for a driving scenario in an area, and a high definition map matching the area; extracting planning messages and perception messages from the record file; and aligning the planning message and the perception messages based on their timestamps. The method further includes calculating an individual performance score for each planning cycle of the ADV for the driving scenario based on the planning messages; calculating a weight for each planning cycle based on the perception messages and the high definition map; and then calculating a weighted score for the driving scenario based on individual performance scores and their corresponding weights.

Abstract: The invention discloses a micro-interface strengthening reaction system for preparing poly-?-olefin, which includes: a first polymerization reactor and a second polymerization reactor that are connected with each other in sequence, wherein a first micro-interface generator is disposed outside the first polymerization reactor, and a second micro-interface generator is disposed inside the second polymerization reactor. A bottom of the second polymerization reactor is provided with a discharge port, and the discharge port is connected with a hydrogen halide removal tower. By disposing the first micro-interface generator in the first polymerization reactor while disposing the second micro-interface generator in the second polymerization reactor, on the one hand it increases the mass transfer area between the gas phase and the liquid phase material, improves reaction efficiency and reduces energy consumption, and on the other hand it results in a higher evenness of the poly-?-olefin and improved product quality.

Abstract: Systems and methods are disclosed for performing combined grant-free and grant-based UL resource allocation. In a particular embodiment, a network entity sends a first type of UL transmission resource assignment selected from two types of UL transmission resource assignment mechanisms to a UE for grant-free transmission and a second type of UL transmission resource assignment from two types of UL transmission resource assignment mechanism to a UE for grant based transmission. The network entity then receives a first data transmission from the UE for grant free transmission using an assigned transmission resource and a second data transmission from the UE for grant based transmission using an assigned transmission resources. Other embodiments pertain to changing the resource allocation scheme from grant free to grant based for a UE, or vice versa. Examples reasons for doing so may include HARQ re-transmissions.

Abstract: The present disclosure provides the use of a recombinant human secretory DDRGK1. Experiments demonstrate that the recombinant human secretory DDRGK1 prepared by the present disclosure can be used in the preparation of biological medicines for treating intervertebral disc degeneration, fractures or bone defects. The recombinant human secretory DDRGK1 of the present disclosure provides a promising direction for the treatment of bone related diseases and has obtained firm scientific evidence, thereby expanding the further application of recombinant human secretory DDRGK1 in clinical practice.

Abstract: A method for calibrating a process model and training an inverse process model of a patterning process. The training method includes obtaining a first patterning device pattern from simulation of an inverse lithographic process that predicts a patterning device pattern based on a wafer target layout, receiving wafer data corresponding to a wafer exposed using the first patterning device pattern, and training an inverse process model configured to predict a second patterning device pattern using the wafer data related to the exposed wafer and the first patterning device pattern.

Abstract: Methods and systems are provided that facilitate sidelink (SL) retransmission scheduled by the network if a SL transmission of a transport block (TB) is unsuccessful. Signalling is used by the network to send a configured grant of transmission resources available for SL transmissions by the UE that repeat on a periodic basis within each of period. The UE makes SL transmissions during one of the periods by transmitting one or more SL transmissions of at least one transport block using the configured resources. The network can schedule a retransmission by transmitting a downlink control information (DCI) to schedule a SL retransmission of one of the transmitted TB. The UE transmits a SL transmission containing a retransmission of the transport block using resources specified in the DCI. The UE transmits a sidelink control information associated with each SL transmission, containing a HARQ process ID for the SL transmission.

Abstract: Methods and systems are provided for signaling for semi-static configuration in grant free uplink transmissions. Radio resource control (RRC) signaling is used to provide information from a base station to a user equipment (UE) that configure the grant free transmission resource to be used by the UE. In some implementations, the RRC signaling may be used in conjunction with system information that is transmitted to all UEs and/or Downlink Control Information (DCI) that the UE needs to access subsequent to the RRC signaling. In some implementations, the DCI includes an activation or deactivation indicator that the UE monitors to determine when the UE is allowed to transmit to the BS or should stop transmitting. Implementations allow for grant free transmission resources to be configured on an individual user based and a group basis.

Abstract: A method for calibrating a process model and training an inverse process model of a patterning process. The training method includes obtaining a first patterning device pattern from simulation of an inverse lithographic process that predicts a patterning device pattern based on a wafer target layout, receiving wafer data corresponding to a wafer exposed using the first patterning device pattern, and training an inverse process model configured to predict a second patterning device pattern using the wafer data related to the exposed wafer and the first patterning device pattern.

Abstract: A double-disc structure for self-biased circulators monolithically integrated on semiconductors is provided. A self-based circulator is attractive due to the great reduction in its size and weight compared to conventional circulators which have bulk permanent magnets. The development of miniaturized self-biased circulators enables monolithic integration of such circulators directly into monolithic integrated circuits (e.g., monolithic microwave integrated circuits (MMICs)) on a single chip and opens the door to full-duplex communication in radio frequency (RF) bands higher than Ka band, without suffering from the additional losses through connectors. This disclosure demonstrates a new double-disc structure by using two self-biased discs in a circulator device, which greatly improve its insertion loss, isolation, bandwidth, and power handling capability.

Abstract: A method for training a machine learning model to generate a predicted measured image, the method including obtaining (a) an input target image associated with a reference design pattern, and (b) a reference measured image associated with a specified design pattern printed on a substrate, wherein the input target image and the reference measured image are non-aligned images; and training, by a hardware computer system and using the input target image, the machine learning model to generate a predicted measured image.

Abstract: A treatment system and method for cephalosporin wastewater are disclosed. The treatment system includes: a flocculation and sedimentation device, an alkali reaction tank, a PAC reaction tank, a PAM reaction tank, a wastewater heat exchanger, a wastewater heater and an oxidation reactor that are connected with each other in sequence, wherein the wastewater heat exchanger is provided with a material inlet, a material outlet, a heat source inlet and a heat source outlet. An oxidized water from the oxidation reactor enters the wastewater heat exchanger from the heat source inlet, the heat source outlet is connected with a product canister, the product canister is connected with a membrane filtration device to realize concentration treatment of a landfill leachate, the material inlet is connected with the PAM reaction tank, and the material outlet is connected with the wastewater heater.

Abstract: A strengthening oxidation system of the external micro-interfacial unit for producing PTA with PX is provided, including: a reactor, a circulating heat exchange device and a micro-interfacial unit. The reactor includes an outer casing and an inner cylinder disposed concentrically inside the outer casing. The circulating heat exchange device is disposed at an exterior of the reactor, and is connected with the outer casing and the inner cylinder respectively, for regulating reaction temperatures of the first reaction zone, the second reaction zone and the third reaction zone inside the reactor in a reaction process of producing PTA with PX.

Abstract: With sidelink reservation signals sent together with the sidelink data, there is the possibility of interference with other sidelink signals. In order to address this, systems and methods are provided in which a first UE transmits a reservation signal to indicate at least one time-frequency resource for transmitting sidelink data. Following this, the first UE transmits at least one sidelink data transmission to a second UE using the at least one time-frequency resource indicated by the reservation signal. The reservation signal is transmitted before the at least one sidelink data transmission signal so that a third UE may detect the reservation signal and use the reservation signal to avoid using the at least one time-frequency resource indicated in the reservation signal.