Patents by Inventor Yu-Chin Lai

Yu-Chin Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090156745
    Abstract: A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising one or more hydrophilic polymers having one or more non-ethylenically-unsaturated carboxylic acid terminated groups.
    Type: Application
    Filed: December 8, 2008
    Publication date: June 18, 2009
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20090142485
    Abstract: A process for treating a silicone hydrogel biomedical device, especially an ophthalmic lens such as a contact lens, involves: immersing the silicone hydrogel biomedical device with a mixture of an organic solvent and a hydrophilic, polymeric material, for a sufficient time that the device is swollen in volume by at least 30%; and removing the organic solvent from the device while retaining at least a portion of the hydrophilic polymeric material therein.
    Type: Application
    Filed: November 18, 2008
    Publication date: June 4, 2009
    Inventors: Yu-Chin Lai, Edmond T. Quinn, Weihong Lang, Daniel M. Ammon, JR., Jay F. Kunzler
  • Publication number: 20090142508
    Abstract: A process for treating a medical device involves: (a) treating a silicon-containing biomedical device with an organic solvent that swells the device, and treating the device with a hydrophilic, monomeric material; and (b) exposing the biomedical device and the hydrophilic, monomeric material to heat or light radiation to polymerize the hydrophilic, monomeric material.
    Type: Application
    Filed: November 14, 2008
    Publication date: June 4, 2009
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20090108479
    Abstract: A method of preparing a biomedical device is disclosed. The method involves the steps: (a) cast molding at least one biomedical device formed from a monomer mixture comprising at least one silicone-containing monomer and at least one hydrophilic monomer in a mold assembly, the mold assembly comprising at least one anterior mold part made of a first plastic material and one posterior mold part made of a second plastic material, wherein the first plastic material is more polar relative to the second plastic material; and (b) contacting a surface of the biomedical device with a solution comprising a proton-donating wetting agent, whereby the wetting agent forms a complex with the hydrophilic monomer on the surface of the biomedical device.
    Type: Application
    Filed: October 26, 2007
    Publication date: April 30, 2009
    Applicant: Bausch & Lomb Incorporated
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20090111942
    Abstract: Disclosed are methods for making a surface modified biomedical device involving (a) exposing a biomedical device having a plurality of biomedical device surface functional groups to one or more ethylenically unsaturated-containing organic compounds having a reactive group that is co-reactive to the biomedical device surface functional groups of the biomedical device; and (b) graft polymerizing a hydrophilic reactive monomer having a complementary reactive functionality with the ethylenically unsaturated functionalities of the ethylenically unsaturated-containing organic compounds on or near the surface of the biomedical device thus forming a biocompatible surface on the biomedical device. The methods disclosed are two-step methods and do not include any additional surface treatment steps.
    Type: Application
    Filed: October 25, 2007
    Publication date: April 30, 2009
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Weihong Lang, Yu-Chin Lai, Daniel J. Hook
  • Publication number: 20090103045
    Abstract: A silicone hydrogel comprising monomeric units of one or more amino monomers, wherein the amino monomers are of formula IA, IB, IIA or IIB and monomeric units of one or more silicone monomers wherein R1, R2 and R3 are independently selected from hydrogen, C1-C6 alkyl or CH2OH; R4 is a C1-C10 alkyl optionally substituted with hydroxyl or carboxylic acid; E is a polymerizable group; X is an anion suitable for quaternary nitrogen; and n is 0, 1, 2, or 3 and m is an integer from 1 to 8.
    Type: Application
    Filed: October 1, 2008
    Publication date: April 23, 2009
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20090092655
    Abstract: Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to surface modifying polymers.
    Type: Application
    Filed: September 30, 2008
    Publication date: April 9, 2009
    Inventors: Weihong Lang, Yu-Chin Lai
  • Patent number: 7482416
    Abstract: Provided are a novel class of fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: January 27, 2009
    Assignee: Bausch & Lomb Incorporated
    Inventors: Yu-Chin Lai, Edmond T. Quinn
  • Publication number: 20090012249
    Abstract: Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 8, 2009
    Inventor: Yu-Chin Lai
  • Publication number: 20090012250
    Abstract: Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having polymerizable functionality that is complimentary to polymerizable hydrophilic polymers.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 8, 2009
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20080314767
    Abstract: Disclosed are ophthalmic solutions such as packaging solutions for storing ophthalmic devices and lens care solutions for cleaning, disinfecting, rinsing and/or storing ophthalmic devices. The ophthalmic solutions contain at least a polymerization product obtained from a monomeric mixture comprising (a) a monomer bearing a center of permanent positive charge and (b) a non-ionic ethylenically unsaturated monomer, wherein the solution has an osmolality of at least about 200 mOsm/kg, and a pH of about 4 to about 9.
    Type: Application
    Filed: June 22, 2007
    Publication date: December 25, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Yu-Chin Lai, Weihong Lang
  • Publication number: 20080312397
    Abstract: Prepolymers comprising at least one block of Formula II and terminated with a polymerizable ethylenically unsaturated radical are useful in hydrogel materials are disclosed: wherein n, R, R1, R2 and X+ are as defined herein.
    Type: Application
    Filed: June 14, 2007
    Publication date: December 18, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Yu-Chin Lai, Weihong Lang, Edmond T. Quinn
  • Publication number: 20080299176
    Abstract: A drug delivery device for placement in the eye includes a drug core comprising a hydrophobic pharmaceutically active agent, and a holder that holds the drug core. The holder is made of a material impermeable to passage of the active agent and includes an opening for passage of the pharmaceutically agent therethrough to eye tissue. The device includes polyurethane-siloxane-containing copolymers crosslinked with hydrophilic monomers.
    Type: Application
    Filed: May 30, 2007
    Publication date: December 4, 2008
    Inventors: Yu-Chin Lai, Ruiwen Shi, O. William Lever, JR., Dominic V. Ruscio, Yan Huang
  • Patent number: 7423074
    Abstract: A polysiloxane copolymer that is useful for forming biomedical devices comprises blocks (I) and (II) and is terminated at each end with an ethylenically unsaturated radical: (*Dii*Diol*Dii*PS)x ??(I) (*Dii*PS)y ??(II) wherein: each Dii is independently a diradical residue of a diisocyanate; each Diol is independently a diradical residue of a diol having 1 to 10 carbon atoms; each PS is independently a diradical residue of a polysiloxane-containing diol or diamine; each * is independently —NH—CO—NH—, —NH—COO— or —OCO—NH—: x represents the number of blocks (I) and is at least 2, and y represents the number of blocks (II) and is at least 1.
    Type: Grant
    Filed: December 2, 2005
    Date of Patent: September 9, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: Yu-Chin Lai, Weihong Lang, Edmond T. Quinn
  • Publication number: 20080197324
    Abstract: An ophthalmic composition comprising a copolymer and one or more cationic antimicrobial components. The copolymer comprises monomeric units of one or more polymerizable alcohols or polymerizable polyols, and monomeric units of one or more polymerizable carboxylic acids. Also, the composition has an osmolality from 200 mOsmol/kg to 400 mOsmol/kg.
    Type: Application
    Filed: May 22, 2007
    Publication date: August 21, 2008
    Inventors: Fang Zhao, Vicki L. Barniak, Weihong Lang, Kimberly Millard, Yu-Chin Lai
  • Patent number: 7411029
    Abstract: Provided are a novel class of fumaric- and itaconic-containing prepolymers and compositions comprising the prepolymers used in the manufacture of medical devices.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: August 12, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: Yu-Chin Lai, Edmond T. Quinn
  • Patent number: 7399795
    Abstract: Provided are surface modified contact lenses formed from one or more fumaric- or itaconic-containing prepolymers having reactive functionality that is complimentary to reactive hydrophilic polymers.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: July 15, 2008
    Assignee: Bausch & Lomb Incorporated
    Inventors: Yu-Chin Lai, Edmond T. Quinn
  • Publication number: 20080143955
    Abstract: A silicone contact lens has a silicate coating on at least one of the contact lens surfaces. The silicate coating is anchored to the bulk silicone contact lens material with a non-silicone polymer layer.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Ravi Sharma, Robert M. Braun, Jay F. Kunzler, Yu-Chin Lai, Daniel M. Ammon
  • Publication number: 20080141628
    Abstract: The present invention is directed to new and improved packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear. In particular, the present invention is directed to a packaging system for storing an ophthalmic device in an aqueous packaging solution comprising hyaluronic acid or a salt thereof. Such solutions are retained on the surface of an unused lens for extended periods of time, resulting in surface modification that persists in the eye, which may provide significant improvement in the wetting properties of fresh contact lenses used for the first time and, moreover, even several hours after lens insertion, thereby preventing dryness and improving lubricity.
    Type: Application
    Filed: December 15, 2006
    Publication date: June 19, 2008
    Applicant: BAUSCH & LOMB INCORPORATED
    Inventors: Weihong Lang, Yu-Chin Lai
  • Patent number: D585439
    Type: Grant
    Filed: April 15, 2008
    Date of Patent: January 27, 2009
    Assignee: Cooler Master Co., Ltd.
    Inventors: Chang Chia Ching, Yang Fan Li, Yu-chin Lai