Abstract: A microfluidic flow restrictor that uses micron-sized beads to impede flow is described. The flow rate can be adjusted by adding or removing the beads using injection needles through self-sealing ports, one injection needle injecting or aspirating beads and another injection needle pushing or pulling fluid from outside of a bead trap within the flow restrictor. In alternative embodiments, the beads or other filler material can be trapped in a manifold bead trap such that they block a subset of fluid channels of the flow restrictor, allowing fluid to flow freely through the rest of the fluid channels. The flow restrictor can be integrated with a contact lens or implantable medical device for use in dispensing liquid therapeutic agents at flow rates of microliters per minute or moving body fluids at a controlled rate from one part of the body to another.

Abstract: A computing device includes a cooling device and a cooling activity monitor configured to assess a cooling activity of the cooling device. A cooling activity reporter is configured to, based at least in part on the cooling activity of the cooling device crossing a predefined cooling activity threshold, communicate a cooling activity indication to a resource manager of the computing device.

Abstract: A method comprises initiating a gaming session for a grid-based game, tracking a number of consecutive losing plays of the grid-based game during the gaming session, and providing a player of the grid-based game with an option to reuse a wild symbol that appears in one play of the number of consecutive losing plays in a next play when the number of consecutive losing plays exceeds a threshold. The method further comprises receiving first input from the player to reuse the wild symbol in the next play, generating, in response to the first input, a sequence of symbols comprising the wild symbol, and causing a display to display the sequence of symbols populated in the array of cells.

Abstract: A switching device is disclosed. In an embodiment a switching device includes at least one stationary contact and a movable contact in a switching chamber configured to contain a gas containing H2, wherein the movable contact is movable by a magnetic armature with a shaft, wherein the shaft projects through an opening in a yoke which is part of a magnetic circuit, and wherein a liner composed of a plastic is arranged in the opening of the yoke, the liner configured to guide the shaft.

Abstract: An implantable device includes a flexible cable, a circuit chip, a fluid adhesion layer, and a vapor deposited layer. The flexible cable includes a lead-in part, a stimulation part and a connection part connected between the lead-in part and the stimulation part. The circuit chip is fixed to a surface of one side of the lead-in part, and is electrically connected to the lead-in part. The fluid adhesion layer is adhered to an outer side of the circuit chip and an outer side of the lead-in part. The vapor deposited layer (4) is directly deposited on an outer side of the fluid adhesion layer.

Abstract: According to examples, an apparatus may include a processor and a memory on which is stored machine-readable instructions that when executed by the processor, may cause the processor to identify configuration information to be used by an on-premise access management service to provide authentication services to applications by users. The processor may also transform the identified configuration information into a transformed set of configuration information to be used by a cloud-based access management service to provide authentication services to the applications by users. In addition, the processor may store the transformed set of configuration information for use by the cloud-based access management service to provide authentication services to the applications by users to migrate authentication of the users from the on-premise access management service to the cloud-based access management service.

Abstract: A microfluidic flow restrictor that uses micron-sized beads to impede flow is described. The flow rate can be adjusted by adding or removing the beads using injection needles through self-sealing ports, one injection needle injecting or aspirating beads and another injection needle pushing or pulling fluid from outside of a bead trap within the flow restrictor. In alternative embodiments, the beads or other filler material can be trapped in a manifold bead trap such that they block a subset of fluid channels of the flow restrictor, allowing fluid to flow freely through the rest of the fluid channels. The flow restrictor can be integrated with a contact lens or implantable medical device for use in dispensing liquid therapeutic agents at flow rates of microliters per minute or moving body fluids at a controlled rate from one part of the body to another.

Abstract: Gaming systems and methods that replicate a symbol driven event obtained at one gaming device at one or more other gaming devices.

Abstract: A cell cultivation apparatus for cultivating microorganisms and growing cells at high density is provided. The apparatus includes a membrane comprising multiple surface features on a first side of the membrane for cell placement. The surface features comprising one or more compartments within which a cell can be located. The membrane includes a material that is at least partially permeable to gas. A second side of the membrane defines a gas region. The second side of the membrane is separated from the first side of the membrane by the membrane. The apparatus further includes a media region for receiving media. The compartments are configured to at least partially reduce media flow shear forces on one or more cells in the compartments. The surface features may be ridges, protrusions, fins, wells, and/or posts.

Abstract: Manufacturing techniques for fabricating a polymer or other substrate optimized for growing cells is described, which takes the form of a micro-thin bag with gas permeable sides. Sides of the bag can be held at a fixed distance from one another with a multitude of tiny micropillars or other spacers extending between them, keeping the bag at a predetermined thickness and preventing the bag from collapsing and the sides from sticking together. In other embodiments, the sides may be held apart by gas pressure alone. A 0.01 ?m to 1000 ?m parylene or other biocompatible coating over the bag outsides controls the permeability of the bag material and provides a bio-safe area for cell growth. An alternate configuration uses open-cell foam with skins coated with a biocompatible coating. Tubes going into multiple bags can be connected to a manifold that delivers gaseous oxygen or removes carbon dioxide and other waste gases.

Abstract: Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.

Abstract: Techniques are described for a non-invasive detection of a health condition of an organ. In an example, the electrical conductivity of the organ reflects the organ's health of. An inductive damping sensor can be used to detect the organ's electrical conductivity and, thus, its health. The inductive damping sensor can be placed in proximity of the organ such as the organ is within the magnetic field generated based on a coil of the inductive damping sensor. The conductivity of the organ impacts the inductance and the resistance of the coil. Hence, the inductance and/or resistance of the coil can be measured, where the measurements can be associated with the health of the organ.

Abstract: An electronic gaming machine (EGM) is provided. The EGM includes a processor circuit and a memory device which stores a plurality of instructions, which when executed by the processor circuit, cause the processor circuit to perform operations. Operations include causing a display device to display multiple game symbols arranged in a symbol selection zone of the display, causing the display device to display multiple value symbols that are assignable to a game symbol based on an input from a user that moves one of the value symbols to be on a selected game symbol. Operations include causing the display device to display multiple symbol display positions with less than all of the game symbols and, responsive to one of the symbol display positions including the selected game symbol, cause the display device to display an award value to be credited to the user.

Abstract: A method comprises initiating a gaming session for a grid-based game, tracking a number of consecutive losing plays of the grid-based game during the gaming session, and providing a player of the grid-based game with an option to reuse a wild symbol that appears in one play of the number of consecutive losing plays in a next play when the number of consecutive losing plays exceeds a threshold. The method further comprises receiving first input from the player to reuse the wild symbol in the next play, generating, in response to the first input, a sequence of symbols comprising the wild symbol, and causing a display to display the sequence of symbols populated in the array of cells.

Abstract: The present disclosure relates generally to systems and methods for providing sliding symbol operations in grid-base games. The sliding symbol operations allow a player of the gaming device to move, by sliding or dragging, a particular symbol from one cell to another in an array of cells between plays of the grid-based game. Movement of the particular symbol from one cell to another allows a player to control their chances of winning and alter the proposed payouts for winning sequences of symbols for at least one subsequent play of the grid-based game.

Abstract: A polymer or other substrate optimized for growing cells is described, which takes the form of a micro-thin bag with gas permeable sides. Sides of the bag can be held at a fixed distance from one another with a multitude of tiny micropillars or other spacers extending between them, keeping the bag at a predetermined thickness and preventing the bag from collapsing and the sides from sticking together. In other embodiments, the sides may be held apart by gas pressure alone. A 0.01 ?m to 1000 ?m parylene or other biocompatible coating over the bag outsides controls the permeability of the bag material and provides a bio-safe area for cell growth. An alternate configuration uses open-cell foam with skins coated with a biocompatible coating. Tubes going into multiple bags can be connected to a manifold that delivers gaseous oxygen or removes carbon dioxide and other waste gases.

Abstract: Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.

Abstract: Medical diagnostic devices and related methods of use are described in which a sensor coil may be connected with a resistive, inductive, and capacitive (RCL) circuit including a power meter and a frequency counter, and the sensor may be positioned on a chest of a subject. The sensor apparatus may apply an alternating current through the sensor coil. The sensor apparatus may measure parallel resistance values in the sensor coil using the power meter for a time interval while the subject inhales and exhales. The sensor apparatus may record the parallel resistance values. The sensor apparatus may determine a first change in the parallel resistance values by measuring a difference between a crest and a trough of the parallel resistance values, wherein the crest of the parallel resistance value corresponds to the inhale and the trough of the parallel resistance value corresponds to the exhale of the subject's breath.

Abstract: Thin parylene C membranes having smooth front sides and ultrathin regions (e.g., 0.01 ?m to 5 ?m thick) interspersed with thicker regions are disclosed. The back sides of the membranes can be rough compared with the smooth front sides. The membranes can be used in vitro to grow monolayers of cells in a laboratory or in vivo as surgically implantable growth layers, such as to replace the Bruch's membrane in the eye. The thin regions of parylene are semipermeable to allow for proteins in serum to pass through, and the thick regions give mechanical support for handling by a surgeon. The smooth front side allows for monolayer cell growth, and the rough back side helps prevents cells from attaching there.